BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0489.0006.p
         (166 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BS_pksL_1 [Q] COG3321 Polyketide synthase modules and related pr...    94   9e-20
all2635 [Q] COG3321 Polyketide synthase modules and related prot...    82   4e-16
BS_pksL_2 [Q] COG3321 Polyketide synthase modules and related pr...    82   4e-16
all1649 [Q] COG3321 Polyketide synthase modules and related prot...    82   4e-16
BS_pksK_3 [Q] COG3321 Polyketide synthase modules and related pr...    82   4e-16

>BS_pksL_1 [Q] COG3321 Polyketide synthase modules and related proteins
          Length = 1814

 Score = 94.0 bits (232), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 49/117 (41%), Positives = 72/117 (61%), Gaps = 14/117 (11%)

Query: 40  DIAVIGMAGRFPGASNVDEYWNNLLYEVDCIGDFPESR--QKGVEGFIQKSVPDSLQKIT 97
           DIA+IG+AGR+P A+N+ E+WNNL    DC+ + PESR   + +EG    S  D      
Sbjct: 324 DIAIIGLAGRYPKAANIHEFWNNLKEGKDCVSEIPESRWDWQRLEGITSPSGKD-----I 378

Query: 98  YEKGGYLEQIDQFDSGYFKISNKESEMMDPIQRLLLTTVMESIEDAXXXXAAAGWSP 154
            + GG+++  D FD  +F+I+ +E+E MDP +RL L T  E+IED       AG++P
Sbjct: 379 SKWGGFIDDPDCFDPQFFRITPREAETMDPQERLFLETCWETIED-------AGYTP 428


>all2635 [Q] COG3321 Polyketide synthase modules and related proteins
          Length = 1565

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 47/130 (36%), Positives = 75/130 (57%), Gaps = 14/130 (10%)

Query: 22  SKVILKEIKQAGVK------KQHKDIAVIGMAGRFPGASNVDEYWNNLLYEVDCIGDFPE 75
           S+ IL  +K+A  K      ++ +++A++GMAGRFPGA NVDE+W+NL   ++ I     
Sbjct: 14  SERILAALKEARTKLEAVELERSEEVAIVGMAGRFPGAKNVDEFWDNLKNGINSIKFLSN 73

Query: 76  SRQKGVEGFIQKSV-PDSLQKITYEKG-GYLEQIDQFDSGYFKISNKESEMMDPIQRLLL 133
                 E  +   V  + L+K  Y +    L  ID+FD+G+F  S +E+E++DP  RL L
Sbjct: 74  ------EDLLANGVKAEDLEKQNYVRAYASLAGIDEFDAGFFGYSPREAEILDPQHRLFL 127

Query: 134 TTVMESIEDA 143
               E++E+A
Sbjct: 128 ECAWEALENA 137


>BS_pksL_2 [Q] COG3321 Polyketide synthase modules and related proteins
          Length = 211

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 9/107 (8%), Positives = 23/107 (21%), Gaps = 6/107 (5%)

Query: 39  KDIAVIGMAGRFPGASNVDEYWNNLLYEVDCIGDFPESRQKGVEGFIQ-KSVPDSLQKIT 97
                + +  R    +       N     + +     S Q       +  +         
Sbjct: 2   NKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYP----V 57

Query: 98  YEK-GGYLEQIDQFDSGYFKISNKESEMMDPIQRLLLTTVMESIEDA 143
                  LE   +    Y K     +   + I +     + +   + 
Sbjct: 58  ANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNGEV 104


>all1649 [Q] COG3321 Polyketide synthase modules and related proteins
          Length = 1570

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 42/103 (40%), Positives = 63/103 (61%), Gaps = 2/103 (1%)

Query: 41  IAVIGMAGRFPGASNVDEYWNNLLYEVDCIGDFPESRQKGVEGFIQKSVPDSLQKITYEK 100
           IA+IG+  RFPGA +   +W  L   VD I + P  R   ++ F  ++ P++  K+    
Sbjct: 4   IAIIGIGCRFPGADSPQAFWQLLSNGVDAITEIPAERWN-IDEFYDRN-PETPGKMNARY 61

Query: 101 GGYLEQIDQFDSGYFKISNKESEMMDPIQRLLLTTVMESIEDA 143
           GG+L Q+D+FD  +F IS +E+ +MDP QRLLL    E++EDA
Sbjct: 62  GGFLSQVDRFDPHFFGISPREALLMDPQQRLLLEVAWEALEDA 104


>BS_pksK_3 [Q] COG3321 Polyketide synthase modules and related proteins
          Length = 1250

 Score = 81.6 bits (200), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 40/104 (38%), Positives = 68/104 (65%), Gaps = 4/104 (3%)

Query: 41  IAVIGMAGRFPGASNVDEYWNNLLYEVDCIGDFPESRQKGVEGFIQKSVPDS-LQKITYE 99
           +A++G++GRFPGA ++DE+W NL    D I + P+ R    E +     PD+ + K   +
Sbjct: 6   VAIVGISGRFPGAMDIDEFWKNLEEGKDSITEVPKDRWDWREHY---GNPDTDVNKTDIK 62

Query: 100 KGGYLEQIDQFDSGYFKISNKESEMMDPIQRLLLTTVMESIEDA 143
            GG+++ + +FD  +F IS +E++ +DP QRLL+T V +++EDA
Sbjct: 63  WGGFIDGVAEFDPLFFGISPREADYVDPQQRLLMTYVWKALEDA 106


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.315    0.134    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 11,001,318
Number of extensions: 460101
Number of successful extensions: 517
Number of sequences better than 1.0e-05: 31
Number of HSP's gapped: 485
Number of HSP's successfully gapped: 31
Length of query: 166
Length of database: 38,378,431
Length adjustment: 98
Effective length of query: 68
Effective length of database: 27,075,699
Effective search space: 1841147532
Effective search space used: 1841147532
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 112 (47.8 bits)