BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0003.p (2437 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0641_7 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 447 e-124 BS_pksK_2 [Q] COG3321 Polyketide synthase modules and related pr... 427 e-118 RSp0641_6 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 412 e-114 all1649 [Q] COG3321 Polyketide synthase modules and related prot... 401 e-111 BS_ppsA_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 399 e-110 >RSp0641_7 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 447 bits (1149), Expect = e-124, Method: Compositional matrix adjust. Identities = 0/882 (0%), Positives = 0/882 (0%), Gaps = 52/882 (5%) Query: 1564 LSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVN 1623 + + + Sbjct: 7 PHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTE 66 Query: 1624 GIPKQFVV-PDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN-LFRAELHRYEE 1681 ++ + P E L Sbjct: 67 TYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYL 126 Query: 1682 SDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIG 1741 Y ++ G + + + V E + Sbjct: 127 DLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGV 186 Query: 1742 SGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNR 1801 +++ + + L ++ G L K Sbjct: 187 MRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYL 246 Query: 1802 SSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELS 1861 + F + S E+ ++ + + + V + + Sbjct: 247 NGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVAS-T 305 Query: 1862 SFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDNDRM 1921 Sbjct: 306 - 364 Query: 1922 SLYDLSCICKMDGGQ--------IEVR---------LEYKTSLFTEETIQNYACYLTHLI 1964 Sbjct: 365 - 423 Query: 1965 NQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVV 2024 Sbjct: 424 483 Query: 2025 FEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPL 2084 Sbjct: 484 543 Query: 2085 DPDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSC 2144 Sbjct: 544 ---------- 593 Query: 2145 YKYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGP 2204 Sbjct: 594 ---------- 643 Query: 2205 QHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPV 2264 Sbjct: 644 703 Query: 2265 LMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEAT 2324 Sbjct: 704 ------ 757 Query: 2325 IWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFR 2384 Sbjct: 758 - 816 Query: 2385 DEETTAGVFRTHPFTD---QIVYHTGDIGKYGMGGQLEYIAR 2423 Sbjct: 817 858 >BS_pksK_2 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1575 Score = 427 bits (1097), Expect = e-118, Method: Compositional matrix adjust. Identities = 290/939 (30%), Positives = 479/939 (51%), Gaps = 94/939 (10%) Query: 47 IAIIGIACRFPFADTLEQYWDNLLNGINGITDFPLKRRKDIDPLLQKVMETPVY--GKGS 104 +AIIGI+C FP A +++W+NL +G I F + + + +++ E Y K S Sbjct: 2 VAIIGISCEFPGAKNHDEFWENLRDGKESIAFFNKEELQRFG-ISKEIAENADYVPAKAS 60 Query: 105 YLEQVDSFDAEYFRLSPKEAEFMDPHQRLMLEVAAEAIEDAGYMGEKIYGTQTGVFIGRD 164 ++ D FD +F++SPK+AEFMDP R++L + +AIEDAGY +I QT VF+ Sbjct: 61 -IDGKDRFDPSFFQISPKDAEFMDPQLRMLLTHSWKAIEDAGYAARQI--PQTSVFMSAS 117 Query: 165 HHSSGLYQQFIDSSNE-------------LAMTGNLPSFISGRIAFFFNLTGPNQVIDTA 211 ++S Y+ + S LA +G +P+ IS ++ L GP+ + Sbjct: 118 NNS---YRALLPSDTTESLETPDGYVSWVLAQSGTIPTMISHKLG----LRGPSYFVHAN 170 Query: 212 CSSGLVALHQGCESLRHKECTMAIVGGISLNLLPLANSSFKIVE------NNDGKVRPFD 265 CSS L+ LH +SL E A+VGG +L+ S+ V ++DG ++ FD Sbjct: 171 CSSSLIGLHSAYKSLLSGESDYALVGGATLH----TESNIGYVHQPGLNFSSDGHIKAFD 226 Query: 266 KNATGTTWGEGLSAIMIKPLREALKDKDRIYSVVKGSGVNSDGASNY-ITAPNPEAQERL 324 +A G GEG++ +++K +A+KD D IY++++G GVN+DGA AP+ + Q + Sbjct: 227 ASADGMIGGEGVAVVLLKKAADAVKDGDHIYALLRGIGVNNDGADKVGFYAPSVKGQADV 286 Query: 325 LIDVWTKAGVHPETISYIETHGTGTVIGDPIEVKAMKQAFDQYTNKKQFCGLGSVKSNIG 384 + V + V PE+I Y+E HGTGT +GDPIE+ A+ + QYTNK QFCG+GSVK+NIG Sbjct: 287 VQQVMNQTKVQPESICYVEAHGTGTKLGDPIELAALTNVYRQYTNKTQFCGIGSVKTNIG 346 Query: 385 HLVGASGMASLIKVILSMKHRQLVPTIHFEEPNPYIPFSQSPFYMVDKPLAWEAAQGPRR 444 HL A+G+A IKV++S+ H++L P+++++EPNP + SPFY+VD+ R Sbjct: 347 HLDTAAGLAGCIKVVMSLYHQELAPSVNYKEPNPNTDLASSPFYVVDQKKTLSREIKTHR 406 Query: 445 AGISSFGFSGMNCHVLLEEWQQEDQQTVREEPEQPRIFPVSAKTKSGLLELLQRYSQ-FL 503 A +SSFG G N H + E+++++ + + + I P+SAK K E LQ Y++ L Sbjct: 407 AALSSFGLGGTNTHAIFEQFKRDSD---KGKIDGTCIVPISAKNK----ERLQEYAEDIL 459 Query: 504 QTHQRADFQN-----LVYTAQLGREHFAHRLAIIAKDASELWRKIAAVLLNDVDQLPESI 558 +R F+N YT Q+GRE HR+ IA +EL +++ D + + Sbjct: 460 AYLERRGFENSQLPDFAYTLQVGREAMEHRVVFIADHVNELKQRL-------TDFINGNT 512 Query: 559 GYYGYFPIRQKAKNNMAQQD-LSEAKTRAAYDKARRLVRQIAENPAQAAEGSLEELAQLY 617 G F Q +K+N + L+E + A L+R+ A+G + +LA+++ Sbjct: 513 AIEGCF---QGSKHNAREVSWLTEDEDSA------ELIRK------WMAKGKVNKLAEMW 557 Query: 618 VQGTRVDWNALWTGQAVQTARLPVYPFTKTRHWPAP------APTEGAFPGVPG--PLLG 669 +G +DW L+ G+ LP YPF K R+WP+ A G G+ PLL Sbjct: 558 SKGAHIDWMQLYKGERPNRMSLPTYPFAKERYWPSQDDRKPVAQISGNQTGIGSIHPLLH 617 Query: 670 ECTVKTAGMRIYAATLSGKEHWLLQEHRILGNGVWPGVAYLEMAKAASGYFFAGE----- 724 + T + + +++ +G E + L++H + G V PGVAYLEMA AA E Sbjct: 618 QNTSDFSEQK-FSSVFTGDE-FFLRDHVVRGKPVLPGVAYLEMAYAAINQAAGSEIGQDV 675 Query: 725 NVVLRQVTLQNMLICPPDETRVVHTIIREEQDHAAFTIASMKEGGHTENWIIHAQGEIYP 784 + L ++ +V ++ EE F I S +E G ++ +IH+QG Sbjct: 676 RIRLNHTVWVQPVVVDRHSAQVDISLFPEEDGKITFDIYSTQEDG--DDPVIHSQGSAEL 733 Query: 785 QAEPKMPVIALEPLIQVMNEESV---ELFTPILTAGIQYGPSWKCIRRFYQNESAAVLHI 841 + + PV L + + + + + + + G+ +GP+++ I+ + + Sbjct: 734 ASAAETPVADLTEMSRRCGKGKMSPDQFYEEGRSRGMFHGPAFQGIKNVNIGNREVLAQL 793 Query: 842 GSTDGASA-REPFSLHPALMDTALSFWHLLRQREEAADLPAFPFYYESIRIFGVMPASFF 900 + S E F LHP++MD+AL + +E PF E + + +S + Sbjct: 794 QLPEIVSGTNEQFVLHPSIMDSALQTATICIMQELTDQKLILPFALEELEVIKGCSSSMW 853 Query: 901 SYVRKRETHGDHRETASYDISLIDEAGNVFAEVENYTLK 939 +Y R ++ DI +IDE+G V ++ ++ + Sbjct: 854 AYARLSDSDHSGGVVQKADIDVIDESGTVCVRIKGFSTR 892 Score = 115 bits (287), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 80/327 (24%), Positives = 144/327 (44%), Gaps = 29/327 (8%) Query: 1241 LEEIERSGSQVMICPCDISDGQQLKHCLMQLREAYGPVKXXXXXXXXXXSGYLFTKDWSD 1300 LE + G++V+ D+SD ++H L +++E YG + ++ K + Sbjct: 1133 LEALRSIGAEVVYREADVSDQHAVRHLLEEIKERYGTLNGIIHGAGSSKDRFIIHKTNEE 1192 Query: 1301 FTRVTAPKIEGTYLLYSLLQEQP-DFFVLFSSIATLEGSPGQGDYAAGNGYLDGFAHFLR 1359 F V PK+ G + ++ P DFF+ FSS++ G+ GQ DYAA N ++D FA + R Sbjct: 1193 FQEVLQPKVSGLLHVDECSKDFPLDFFIFFSSVSGCLGNAGQADYAAANSFMDAFAEYRR 1252 Query: 1360 ------RKGVRGLTLNWAAWEETGMAL----DNGALGSKIYRPLKTGTAVHAFSRALQLE 1409 ++ ++ NW WEE GM + + L + P+ T + + AF + + + Sbjct: 1253 SLAASKKRFGSTISFNWPLWEEGGMQVGAEDEKRMLKTTGMVPMPTDSGLKAFYQGIVSD 1312 Query: 1410 EPRVIIADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVI 1469 +P+V + + +L ++ + + D R+ Q R + A A+I GA++ Sbjct: 1313 KPQVFVMEGQLQKMKQKLLSAGSKAKRNDQRKADQDQGQTRKLEA-----ALIQMVGAIL 1367 Query: 1470 SEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYP 1529 +D++ E G DS+ T N +N + +L+ FEY Sbjct: 1368 K-------------VNTDDIDVNTELSEYGFDSVTFTVFTNKINEKFQLELTPTIFFEYG 1414 Query: 1530 TVSGLAAYLEQSLPSRNEATAKAAGSE 1556 +V LA Y+ + A A G + Sbjct: 1415 SVQSLAEYVVAAYQGEWNQDATAKGKD 1441 >RSp0641_6 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 412 bits (1060), Expect = e-114, Method: Compositional matrix adjust. Identities = 0/879 (0%), Positives = 0/879 (0%), Gaps = 57/879 (6%) Query: 1564 LSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTIIKNVN 1623 + + + Sbjct: 7 PHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTE 66 Query: 1624 GIPKQFVV-PDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN-LFRAELHRYEE 1681 ++ + P E L Sbjct: 67 TYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYL 126 Query: 1682 SDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLWIG 1741 Y ++ G + + + V E + Sbjct: 127 DLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGV 186 Query: 1742 SGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAKNR 1801 +++ + + L ++ G L K Sbjct: 187 MRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYL 246 Query: 1802 SSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRELS 1861 + F + S E+ ++ + + + V + + Sbjct: 247 NGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVAS-T 305 Query: 1862 SFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDNDRM 1921 Sbjct: 306 --- 362 Query: 1922 SLYDLS--------CICKMD--------GGQIEVRLEYKTSLFTEETIQNYACYLTHLIN 1965 Sbjct: 363 422 Query: 1966 QVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVF 2025 Sbjct: 423 - 481 Query: 2026 EGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLD 2085 Sbjct: 482 541 Query: 2086 PDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCY 2145 Sbjct: 542 ------ 595 Query: 2146 KYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQ 2205 Sbjct: 596 ----------- 644 Query: 2206 HHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVL 2265 Sbjct: 645 704 Query: 2266 MNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATI 2325 Sbjct: 705 ------------- 751 Query: 2326 WATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRD 2385 Sbjct: 752 --- 808 Query: 2386 EETTAGVFRTHPFT-DQIVYHTGDIGKYGMGGQLEYIAR 2423 Sbjct: 809 847 >all1649 [Q] COG3321 Polyketide synthase modules and related proteins Length = 1570 Score = 401 bits (1031), Expect = e-111, Method: Compositional matrix adjust. Identities = 211/520 (40%), Positives = 320/520 (61%), Gaps = 20/520 (3%) Query: 45 DDIAIIGIACRFPFADTLEQYWDNLLNGINGITDFPLKRRKDIDPLLQKVMETPVYGK-- 102 + IAIIGI CRFP AD+ + +W L NG++ IT+ P +R +ID + ETP GK Sbjct: 2 EPIAIIGIGCRFPGADSPQAFWQLLSNGVDAITEIPAERW-NIDEFYDRNPETP--GKMN 58 Query: 103 ---GSYLEQVDSFDAEYFRLSPKEAEFMDPHQRLMLEVAAEAIEDAGYMGEKIYGTQTGV 159 G +L QVD FD +F +SP+EA MDP QRL+LEVA EA+EDAG + E++ G++TGV Sbjct: 59 ARYGGFLSQVDRFDPHFFGISPREALLMDPQQRLLLEVAWEALEDAGIVREQLTGSKTGV 118 Query: 160 FIG-RDHHSSGLYQQFIDSSNELAMTGNLPSFISGRIAFFFNLTGPNQVIDTACSSGLVA 218 F+G + S ++ +F + +TGN + +GR+++ FNL GP+ +DTACSS LVA Sbjct: 119 FVGISTNDYSRIHPEFDSNPQGYDLTGNCINIAAGRLSYLFNLRGPSLAVDTACSSSLVA 178 Query: 219 LHQGCESLRHKECTMAIVGGISLNLLPLANSSFKIVE--NNDGKVRPFDKNATGTTWGEG 276 +H C+S+ ++E +MAI G++L L P+ N + ++ + DG+ + FD++A G EG Sbjct: 179 VHLACQSIWNQESSMAIASGVNLVLSPIGNIALSKLKALSPDGRCKTFDESANGYVRSEG 238 Query: 277 LSAIMIKPLREALKDKDRIYSVVKGSGVNSDGASNYITAPNPEAQERLLIDVWTKAGVHP 336 I++KP+ +AL D D IY+V++GS +N DG S +T P AQE L+ +A V P Sbjct: 239 AGCIILKPIAQALADHDPIYAVIRGSAINHDGRSKGLTVPYGPAQESLIRQALQQAQVQP 298 Query: 337 ETISYIETHGTGTVIGDPIEVKAMKQAFDQYTNKKQFCGLGSVKSNIGHLVGASGMASLI 396 + ISY+E HGTGT +GDPIE A+ + + C +G+VKSNIGHL A+G+AS+I Sbjct: 299 KEISYVELHGTGTPLGDPIEAMAIGAVLGEGRDAAHPCLVGAVKSNIGHLEAAAGIASII 358 Query: 397 KVILSMKHRQLVPTIHFEEPNPYIPFSQSPFYMVDKPLAWEAAQGPRRAGISSFGFSGMN 456 K+ L++K++Q+ P++HF +PNPYIPF Q P + + W ++ +AG+SSFGFSG N Sbjct: 359 KMALALKYQQIPPSLHFHQPNPYIPFDQLPLRVQTSLIPWPKSKYGAKAGVSSFGFSGTN 418 Query: 457 CHVLLE---EWQQEDQQTVREEPEQPRIFPVSAKTKSGLLELLQRYSQFLQTHQRAD--F 511 HV+LE + +QQT + P + P+SA T + + L Y + + Sbjct: 419 AHVILEGVSSFNSPEQQTCKF----PHLLPLSAHTPAAVQTLALGYQDLINAQKLTPEFV 474 Query: 512 QNLVYTAQLGREHFAHRLAIIAKDASELWRKIAAVLLNDV 551 QNL Y+A + R H ++R A++ +L + A+ D+ Sbjct: 475 QNLCYSASVRRTHQSYRSAVVVNSPEDLPSCLQALATADI 514 Score = 114 bits (284), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 87/316 (27%), Positives = 142/316 (44%), Gaps = 19/316 (6%) Query: 1234 TSRKIELLEEIERSGSQVMICPCDISDGQQLKHCLMQLREAYGPVKXXXXXXXXXXSGYL 1293 + K + + +E G+ V + D+SD QQ+ Q++ ++ + Sbjct: 1207 SEEKQQKIRALENQGATVKVVAADVSDYQQMSQLFAQIQLNSPKLRGIIHAAGVLNDCSI 1266 Query: 1294 FTKDWSDFTRVTAPKIEGTYLLYSLLQEQP-DFFVLFSSIATLEGSPGQGDYAAGNGYLD 1352 D FT+V PK+ G + L+ L Q+ DFFV FSS++ L GS GQ YAA N +LD Sbjct: 1267 AQMDSETFTKVFQPKVTGAWNLHQLTQDLSLDFFVCFSSMSALLGSRGQLHYAAANSFLD 1326 Query: 1353 GFAHFLRRKGVRGLTLNWAAWEETGMALDNGALGSKIY--RPLKTGTAVHAFSRALQLEE 1410 G + + G+ GL++NW W E GMA +G K PL+ A+ L Sbjct: 1327 GLVYHRQSLGLPGLSINWGPWAEGGMATQGYEVGLKRMGIEPLEPTAALQVLGGLLGSAS 1386 Query: 1411 PRVIIADIRLDQLDESVTGK--------LPLQLSPDLRRTGNRFAQPRPVAAAADTIAII 1462 + ++A I + V K L Q S D G F Q A A++ Sbjct: 1387 MQTMVAAINWSAFGKIVAAKGRVAFLEALLTQESKD-GSNGENFRQKLSAAPLHRRPALL 1445 Query: 1463 GHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSI 1522 ++++Q VAQ+ + G ++ + F+++G DS+M+ Q + L L L Sbjct: 1446 ------TTQVQQEVAQVLGHS-GSYVPEVEQGFFDMGMDSLMSVQFRHSLEALLAVSLPS 1498 Query: 1523 AEIFEYPTVSGLAAYL 1538 +FE P++ + +YL Sbjct: 1499 TLVFECPSIGDVVSYL 1514 Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 72/300 (24%), Positives = 136/300 (45%), Gaps = 25/300 (8%) Query: 875 EAADLPAFPFYYESIRIFGVMP--------ASFFSYVRKRETHGDHRETASYDISLIDEA 926 + DLP +P+ ES + P +S + + +T +E +++ L EA Sbjct: 860 QMVDLPLYPWQRESYWVSESQPQFQKALPASSLLNLLVAGKTEQLTQELSNHH-QLSPEA 918 Query: 927 GNVFAEVENYTLKKVSPALISKDLF---YRINWVKSPRP-DGGSRIGGTVLLFGNDCRAT 982 ++ S A I++DL YRI W SP D + L+F ++ Sbjct: 919 KQFIPQLLQLLATGKSTAKITQDLSNARYRIEWQLSPLTVDNKTSEAERWLIFSDNQGLG 978 Query: 983 REFIRHMEAGDVELIQVVQGEAYRKEKDSRYVVG-NAAADYIQLFADLQGRNVSRMIHGY 1041 +E + + I V GE+Y K S Y + + AAD+ QL AD+ ++++++ + Sbjct: 979 QELAAVV---NDSCILVSSGESYEKLSSSHYQINPHQAADFQQLLADI-SEPITKVVYLW 1034 Query: 1042 ALDEDSGADSLSSLQAVQEKSVQSLFFIIKALVQAKYKEQIELVLLGKQGYEVTGGEKEL 1101 +LD S +L+ Q + L ++++AL + K +L + +Q VT ++ Sbjct: 1035 SLD------SSINLENSQPQCYSHLLYLVQALAKISSKIAPQLWIGTQQAQAVTPSCHQI 1088 Query: 1102 EPCYAAFYNLGKVADTEYPNLKCRSIDLGDE-TEWGAVLEEIFGERTANQVAYRENKRFI 1160 + +G+V EYP L ID G++ A++ E+ + ++VA+R+ KR++ Sbjct: 1089 NVAQTPLWGMGQVIALEYPQLWGGLIDFGNQDVAATAIIAEMTAKTGEDRVAFRDGKRYV 1148 >BS_ppsA_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 792 Score = 399 bits (1025), Expect = e-110, Method: Compositional matrix adjust. Identities = 0/883 (0%), Positives = 0/883 (0%), Gaps = 55/883 (6%) Query: 1562 YDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLRTII-K 1620 L +++ L + + ++V + L Sbjct: 7 SPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLDQSGVN 66 Query: 1621 NVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN-LFRAELHRY 1679 D + + + Sbjct: 67 QRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQ------PELENAIREAYAQLSADDE 120 Query: 1680 EESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQEKLW 1739 S + + D G L + + Sbjct: 121 NASFAVRSSATAEDMPDASFAGQQETFLNVQGFDA------VLVAVKHVFASLFNDRAIS 174 Query: 1740 IGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRLLAK 1799 + + Q + +L + G ++ ++ Sbjct: 175 YRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQG 234 Query: 1800 NRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVDFRE 1859 + + + + + QE + + R F Sbjct: 235 AVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHGKQVKIEDVPQEQRDIFSL 294 Query: 1860 LSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQDND 1919 + L + + K Y P + Sbjct: 295 TNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQARPETVRSRGQVMERYTLHS 354 Query: 1920 -------------RMSLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYACYLTHLINQ 1966 R+ + I + + + T+ + + ++ Sbjct: 355 QGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPDWEPIMKKASAIVTN 414 Query: 1967 VIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPD-QVCRLFEAQVEQNPDQTAVVF 2025 L + + N + + + Sbjct: 415 RGGRTCHAAIIARELGIPAVVGCGDATERMKDGENVTVSCAEGDTGYVYAELLEFSVKSS 474 Query: 2026 EGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLD 2085 E + L + N + GV L R +I ++G+ Sbjct: 475 SVETMPDLPLKVMMNVGNPDR-AFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQ 533 Query: 2086 PDFPPERIAYMIRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCY 2145 I M++ L I + A Sbjct: 534 EPQLQNEIREMMKGFDSPRE------------FYVGRLTEGI----ATLGAAFYPKRVIV 577 Query: 2146 KYSDIRKQPVARIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQ 2205 + SD + A + E G G + V S + + ++ + Sbjct: 578 RLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFALECEAVKRVRNDMG 637 Query: 2206 HHMML-VTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPV 2264 + + + + + L + + F Sbjct: 638 LTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDG 697 Query: 2265 LMNQFLFGLSSQDEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRA-KLYNLYGPTEA 2323 + V+ + + + + + A K G Sbjct: 698 FSIGSNDMTQLALGL----DRDSGVVSELFDERNDAVKALLSMAIRAAKKQGKYVGICGQ 753 Query: 2324 TIWATYYEAA--SDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPG 2381 AA + + Sbjct: 754 GPSDHEDFAAWLMEEGIDS- 812 Query: 2382 YFRDEETTAGVFRTHPF-TDQIVYHTGDIGKYGMGGQLEYIAR 2423 Sbjct: 813 855 Score = 73.6 bits (179), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 0/450 (0%), Positives = 0/450 (0%), Gaps = 54/450 (12%) Query: 1431 LPLQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMD 1490 Sbjct: 936 ---------- 985 Query: 1491 ISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATA 1550 Sbjct: 986 ---- 1041 Query: 1551 KAAGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQI----REAIDLAVLQQGLD 1606 Sbjct: 1042 ----------- 1090 Query: 1607 ILTRRHSSLRTII-KNVNGIPKQFV--VPDKSHV---IHFTDYAQEPHXXXXXXXXXXXX 1660 Sbjct: 1091 1150 Query: 1661 NT---TAFELEQN-LFRAELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRS 1716 Sbjct: 1151 - 1209 Query: 1717 KRPIQLAPIALQPVDWVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDR-PHSI 1775 Sbjct: 1210 -- 1267 Query: 1776 AYDGSYIKFTVSEEVTGQLRLLAKNRSST----LYMTVLAIYFLFLKKLSQEEDIIVGFP 1831 Sbjct: 1268 --- 1324 Query: 1832 VSGREQQ----EWENIIGLFMNMVCIRVDF 1857 Sbjct: 1325 1354 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 180,181,317 Number of extensions: 7761571 Number of successful extensions: 18823 Number of sequences better than 1.0e-05: 252 Number of HSP's gapped: 18049 Number of HSP's successfully gapped: 311 Length of query: 2437 Length of database: 38,378,431 Length adjustment: 123 Effective length of query: 2314 Effective length of database: 24,192,349 Effective search space: 55981095586 Effective search space used: 55981095586 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 124 (52.4 bits)