BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0486.0007.p (549 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 180 7e-45 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 177 5e-44 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 145 2e-34 SP0661 [T] COG4753 Response regulator containing CheY-like recei... 125 1e-28 SPy1556 [T] COG4753 Response regulator containing CheY-like rece... 120 6e-27 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 180 bits (456), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 140/563 (24%), Positives = 263/563 (46%), Gaps = 61/563 (10%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 MYK++LA+DE VR G+ + I+WE+ G+EV +A+NG +A + + PD+V+TDI+MP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 MNGLQLAEWIRNRHP-NTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKV 119 +GLQL + + NTK II++GY++F YAQKA++ +++LKP EL L+K+ Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 RSAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRG- 178 + ++ E A + + +L + F+ SL + + E+ +A+ I+ R Sbjct: 121 AATLDQEKATNSD---------QEKVLLDQIFIHSLGENK-KENEVRRWAAKLNINNRHF 170 Query: 179 ---ELFQASVISVDYIREGGGGEAVSSRPVS--LRDTGDRNLQLFAVLNIAEEICQKHSF 233 L + + +S+D G P+ +R+T R I E++ H++ Sbjct: 171 YYYLLLEVNNLSLD----KGFINEQYKEPIRKVIRETVARQAATEEYTAIYEQL--DHAY 224 Query: 234 GKVFIHRDNXXXXXXXXXXXXASITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSL 293 G + G+ + E++R+++Q F + +T G S Sbjct: 225 GLLITSE------------HLKKFNGQIEPLAEKLRKDIQDFTNIPLTVYVGAKTDDLST 272 Query: 294 LSQSFNDALQALDYRLILGNNRVIWIEDVESRVGRMLAYDELTQQ---SLIRTIKLGTLQ 350 + +S+ A +Y+ I V E ES YDEL +L+ ++ Sbjct: 273 IKKSYETANSLRNYKYIFNEKNVFIHEQTESVDT---TYDELNNHLFVTLMEQMEENNSD 329 Query: 351 ELKEVVDELFGGLDAAQVSTQEYQIFLLEIITTILRVAKE---------SGSELNDYPGL 401 + ++D++F + + + + +++ + S + ++ Sbjct: 330 RIVNIIDKIFSEFQTKKFVPSAVKTSVNRCVHKVMQTVQAMEGDTGKIISAQAMTNWESY 389 Query: 402 GFTSLSEIHKFNNMGEAKEWIIGVCSRLMDSIAMERQSSYKQLIDQAKDYIRSHYEESDI 461 T F+ + + + + ++ + R+ + K I + K YI +HY E +I Sbjct: 390 NLT-------FDQLKQVFTKFVLEAAVIIQEL---RKENMKSDIYKVKTYIENHYHE-NI 438 Query: 462 SIGRVCQHLHISTGYFSSIFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGF 521 S+ + +++ Y +FKK + F YLL++R+ AK+LLR T+++ +E+AER+GF Sbjct: 439 SLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGF 498 Query: 522 ADPNYFSFCFRKKYGQSPKEYKN 544 +YF F K +P EY+N Sbjct: 499 GSTDYFVTQFEKINKMTPTEYRN 521 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 177 bits (448), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 142/548 (25%), Positives = 256/548 (46%), Gaps = 34/548 (6%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 M+K+++ +DEE V G+ I W+ G E V +A NGR D + P +V+TDI MP Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 M GL + + +R + +++IL+GY EFE+A+KA++L I +Y+ KP S + VL +V Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 121 SAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRGEL 180 + +E + ++ + L+ ++ P++ +++ SL++ RLR EI E+ + + Sbjct: 121 NKLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNGEIPEEFLAKITKWKDQQ 180 Query: 181 FQASVISVDYIREGGGGEAVSSRPVSLRDTGDRNLQLFAVLNIAEEICQKHSFGKVFIHR 240 A ++ D G + +P D L ++V + E+ + ++ Sbjct: 181 HIACSLTYD------GPQNKELKP------ADWYLFRYSVHKMIREVLNGYPIDFRYLEM 228 Query: 241 DNXXXXXXXXXXXXAS---ITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSLLSQS 297 D S ++ I +++ Q + + T G + LS+S Sbjct: 229 DAYRSALCLHVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLSES 288 Query: 298 FNDALQALDYRLILGNNRVIWIEDVESRVGRMLAYDELTQQSLIRTIKLGTLQELKEVVD 357 F++A LGN ED G + + Q L I+ KEV++ Sbjct: 289 FHEACME-SQSFPLGNP----YED-----GTRATFPMESSQKLYDAIRYADATRAKEVLE 338 Query: 358 ELFGGLDAAQVSTQEYQIFLLEIITTILRVAKESGSELNDYPGLGFTSLSEIHKFNNMGE 417 E G L ST +EI T I + G + + F + K G Sbjct: 339 EAVGVLGEVPYSTLVGYKVGIEIWTIITYSLYDIGILIQEMFDEDFDLAQHLTK---QGN 395 Query: 418 AKEWIIGVCSRLMDSIAMERQS----SYKQLIDQAKDYIRSHYEESDISIGRVCQHLHIS 473 +EWI +C ++ + I +Q +KQLI+Q YI H E +I++ + L+IS Sbjct: 396 WQEWIRFLCEQI-EHICYHQQWDENIKHKQLIEQVMIYIEKHLAE-NITLQDIADELYIS 453 Query: 474 TGYFSSIFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGFADPNYFSFCFRK 533 Y IFKK + +F +Y+ ++R+E AK++++ +E++E++G+ +P YF+ F+K Sbjct: 454 RNYLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKK 513 Query: 534 KYGQSPKE 541 G +P++ Sbjct: 514 YTGYTPRD 521 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 145 bits (366), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 131/552 (23%), Positives = 257/552 (46%), Gaps = 37/552 (6%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 M +++ +DE+ REG+ + ++ +V +A NGR+A + PD+++ DI+MP Sbjct: 1 MINVLIVDDEQIEREGLKLFLK-DRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPG 59 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 ++G+Q + I+ + P T+ I+++ +D FEYA++ ++ + EY+LKP + ++++ L ++ Sbjct: 60 VDGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIV 119 Query: 121 SAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRGEL 180 IE EK + + L + + ++ + + L+ ++ E E+ LR E Sbjct: 120 GEIEQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDYEW----MEWNEWLRTEQ 175 Query: 181 FQASVISVDYIREGGGGEAVSSRPVSLRDTGDRNLQLFAVLNIAEEICQKHSFGKVFIHR 240 + + + ++G + R + LQL K + G H Sbjct: 176 -EGYAVVFSFHQQGKEIRKTEKQQWHARIKKEIGLQL-----------PKSTVGPFIGH- 222 Query: 241 DNXXXXXXXXXXXXASITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSLLSQSFND 300 + + R +++ + + Q V G G + S S+ + Sbjct: 223 -HLPILMLTENENGMTKQEREQVVIQLLHKVKQAVQPAKVKTGVG-GIYRLHFFSTSYRE 280 Query: 301 ALQALDYRLILGNNRV---IWIEDVESRVGRMLAYDELTQQSLIRTIKLGTLQELKEVVD 357 AL ALD +I + + + ++V+ R L + + LI IK G ++ + D Sbjct: 281 ALLALD--IIYDHKQASYYFYDKNVKIRADEQLPIER--ENKLIEAIKSGDGEKALQAFD 336 Query: 358 ELFGG-LDAAQVSTQEYQIFLLEIITTILRVAKESGSELNDYPGLGFTSLSEIHKFNNMG 416 L ++ + + +L ++ + R+ E G L+ F S +H+ G Sbjct: 337 HYVQAILRCSKHPLHDMRKYLQQLFIILGRLLNEMG--LHWETAQDFARFSTVHQVTEHG 394 Query: 417 EAKEWIIGVCSRLMDSIAMERQSSYKQLIDQAKDYIRSHYEESDISIGRVCQHLHISTGY 476 +++ I+ + L + + QS L+ A+DY+ H+ E +++ + +H+ +S Y Sbjct: 395 KSE--ILHIVRTLQEWRTTDEQS----LMLLARDYVHDHFREP-LTLDDLAKHIGLSPYY 447 Query: 477 FSSIFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGFADPNYFSFCFRKKYG 536 S +FK+ +TF Y+ Q+R+E AK+LL T+ EI IG+ DPNYFS F+K G Sbjct: 448 VSKLFKERFDLTFSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTG 507 Query: 537 QSPKEYKNSSRG 548 +SP +Y+ S G Sbjct: 508 KSPSDYRKSING 519 >SP0661 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 245 Score = 125 bits (315), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 55/143 (38%), Positives = 98/143 (68%) Query: 2 YKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPFM 61 Y +++ EDE VR+G+ ++ Y E++ QAENGR+A + I + +PD+++TDI MP + Sbjct: 3 YTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWELIQKQVPDIILTDINMPHL 62 Query: 62 NGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVRS 121 NG+QLA +R +P ++ LTGYD+F+YA A+KL +D+Y+LKPFS Q++ ++L K++ Sbjct: 63 NGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDDYLLKPFSRQDIEEMLGKIKQ 122 Query: 122 AIEAEIAEKENVFVLSEHYRKSL 144 ++ E E++ +L+ + ++ Sbjct: 123 KLDKEEKEEQLQDLLTNRFEGNM 145 Score = 66.2 bits (160), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 38/92 (41%), Positives = 61/92 (66%) Query: 452 IRSHYEESDISIGRVCQHLHISTGYFSSIFKKEMKMTFVSYLLQIRLEAAKELLRSTELK 511 I+SH +S S+ + L S Y SS+ KKE+ + F YL++ R++ AK LL +T+LK Sbjct: 149 IQSHLADSQFSLKSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLK 208 Query: 512 AFEIAERIGFADPNYFSFCFRKKYGQSPKEYK 543 +EIAE++GF D NYF+ F++ G +P+++K Sbjct: 209 IYEIAEKVGFEDMNYFTQRFKQIAGVTPRQFK 240 >SPy1556 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 246 Score = 120 bits (301), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 58/124 (46%), Positives = 86/124 (69%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 MY L++ EDE VR+GI + +D+ Q+ + V++AENG+ A D + D+V+TDI MP Sbjct: 1 MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPK 60 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 +NG+QLAE I+ P T ++ LTGYD+F YA A+KL D+Y+LKPFS ++ D+L K+R Sbjct: 61 LNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLR 120 Query: 121 SAIE 124 +E Sbjct: 121 KKLE 124 Score = 72.8 bits (177), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 42/98 (42%), Positives = 61/98 (62%), Gaps = 3/98 (3%) Query: 452 IRSHYEESDISIGRVCQHLHISTGYFSSIFKKEMKMTFVSYLLQIRLEAAKELLRSTELK 511 I +SD+++ + Q L S Y S + KKE+ M F YL+Q RL+ AK LL ++ LK Sbjct: 150 IHERLADSDLTLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLK 209 Query: 512 AFEIAERIGFADPNYFSFCFRKKYGQSPKEYKNSSRGG 549 +EIAE++GF D NYFS F++ G +P +YK +GG Sbjct: 210 IYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYK---KGG 244 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,421,225 Number of extensions: 1434372 Number of successful extensions: 4926 Number of sequences better than 1.0e-05: 379 Number of HSP's gapped: 5010 Number of HSP's successfully gapped: 391 Length of query: 549 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 438 Effective length of database: 25,576,357 Effective search space: 11202444366 Effective search space used: 11202444366 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)