BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0486.0005.p
         (154 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ZphnO [KR] COG0454 Histone acetyltransferase HPA2 and related ac...    63   2e-10
phnO [KR] COG0454 Histone acetyltransferase HPA2 and related ace...    63   2e-10
ZphnO [KR] COG0454 Histone acetyltransferase HPA2 and related ac...    62   3e-10
all2223 [KR] COG0454 Histone acetyltransferase HPA2 and related ...    51   7e-07
CAC2468 [KR] COG0454 Histone acetyltransferase HPA2 and related ...    49   3e-06

>ZphnO [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 144

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 44/105 (41%), Positives = 62/105 (59%), Gaps = 4/105 (3%)

Query: 49  DPFHCTLVAELDNEVVGMVGLRKVRSYYKQADCITEITALIVAEELRGNGLGKRLVAAAE 108
           DP     +A LD EVVGM+GL  ++ +    + I EI  L+V  + RG  +G +L+A AE
Sbjct: 44  DPNMRYHLALLDGEVVGMIGLH-LQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE 102

Query: 109 EWARQKGCCELFLRSGNRVERAPAHAFYRHIGFEKTAGYRFNKSL 153
           E ARQ G  E+   S N V+R  AH FY   G+E++  +RF K+L
Sbjct: 103 EEARQAG-AEMTELSTN-VKRHDAHRFYLREGYEQSH-FRFTKAL 144


>phnO [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 301

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 7/105 (6%), Positives = 19/105 (18%), Gaps = 4/105 (3%)

Query: 49  DPFHCTLVAELDNEVVGMVGLRKVRSYYKQADCITEITALIVAEELRGNGLGKRLVAAAE 108
                 +  E   + + +     +    K+A       A   +       +         
Sbjct: 44  RHRIVGIHTEGAYQAIYVDTPG-LHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT 102

Query: 109 EWARQKGCCELFLRSGNRVERAPAHAFYRHIGFEKTAGYRFNKSL 153
                    +L       V  A           +    +    + 
Sbjct: 103 PDDEMVL-NKLREGKAP-VILAVNKVDNVQEKADLLP-HLQFLAS 144



 Score = 62.4 bits (150), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 3/105 (2%), Positives = 16/105 (15%), Gaps = 4/105 (3%)

Query: 49  DPFHCTLVAELDNEVVGMVGLRKVRSYYKQADCITEITALIVAEELRGNGLGKRLVAAAE 108
              + T         +         ++    +       +     L    +   +    +
Sbjct: 9   ATQYDTDAVYALICELKQAEFD-HHAFRVGFNANLRDPNMRYHLALLDGEVVGMIGLHLQ 67

Query: 109 EWARQKGCCELFLRSGNRVERAPAHAFYRHIGFEKTAGYRFNKSL 153
                       ++    V                       ++ 
Sbjct: 68  FHLHHVN-WIGEIQELV-VMPQARGLNVGSKLLAWAE-EEARQAG 109


>all2223 [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 153

 Score = 50.8 bits (120), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 35/107 (32%), Positives = 58/107 (54%), Gaps = 16/107 (14%)

Query: 50  PFHCTLVAELDNEVVGMVGLRKV-----RSYYKQA--DCITEITALIVAEELRGNGLGKR 102
           P + T +A L+ + VG   L        R Y+K A  D +T I+++      RG G+G +
Sbjct: 45  PNYHTYIAYLNQQPVGTFSLLYAPTMMHRGYHKFAVLDSVTVISSM------RGEGIGSQ 98

Query: 103 LVAAAEEWARQKGCCELFLRSGNRVERAPAHAFYRHIGFEKTAGYRF 149
           +V AA + +   GC ++ L S   ++R+ AH FY+ +GFE+  G+ F
Sbjct: 99  MVKAALKLSADAGCYKVMLSS--NLKRSRAHQFYQSLGFEQH-GWSF 142


>CAC2468 [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 301

 Score = 48.9 bits (115), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 6/65 (9%), Positives = 15/65 (23%), Gaps = 3/65 (4%)

Query: 85  ITALIVAEELRGNGLGKRLVAAAEEWARQKGCCELFLRSGNRVERAPAHAFYRHIGFEKT 144
           I  L+        G  + ++   E          +  +      +AP       +   + 
Sbjct: 74  INRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREG--KAPVILAVNKVDNVQE 131

Query: 145 A-GYR 148
                
Sbjct: 132 KADLL 136


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.322    0.136    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 10,832,882
Number of extensions: 390332
Number of successful extensions: 811
Number of sequences better than 1.0e-05: 6
Number of HSP's gapped: 816
Number of HSP's successfully gapped: 6
Length of query: 154
Length of database: 38,378,431
Length adjustment: 97
Effective length of query: 57
Effective length of database: 27,191,033
Effective search space: 1549888881
Effective search space used: 1549888881
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 111 (47.4 bits)