BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0479.0023.p (601 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa1715 [F] COG1001 Adenine deaminase 477 e-134 BH0640 [F] COG1001 Adenine deaminase 290 4e-78 BS_adeC [F] COG1001 Adenine deaminase 281 2e-75 AGc4165 [F] COG1001 Adenine deaminase 270 4e-72 SMc01533 [F] COG1001 Adenine deaminase 270 6e-72 >SMa1715 [F] COG1001 Adenine deaminase Length = 595 Score = 477 bits (1227), Expect = e-134, Method: Compositional matrix adjust. Identities = 269/595 (45%), Positives = 357/595 (60%), Gaps = 7/595 (1%) Query: 6 KPLADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVSHM 65 +P ++ P LV A G PA LV+ G+ VNV SGEI+ G +A+ GGR AYVG D H Sbjct: 3 QPWSEIAPRLVDVAMGRKPADLVVRNGRWVNVYSGEIVPGADIAIVGGRFAYVGPDAGHT 62 Query: 66 IGEGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVFG 125 IGEGT++++AAGRY+ PG+ DGH H+ES +TVTEFARAV+P GTT F D HEIANV G Sbjct: 63 IGEGTKIVDAAGRYLVPGLCDGHMHVESGLVTVTEFARAVIPHGTTTMFVDPHEIANVLG 122 Query: 126 LKGIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALGE 185 + G++LM +E + P+ ++QV SCVPSA P E GA++ +V EA W ++I LGE Sbjct: 123 IAGVKLMNDEAQTLPVNIFVQVPSCVPSA-PGLENAGATLSAADVREALAW-PNIIGLGE 180 Query: 186 VMNFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECVTAED 245 +MNFPGV DSKM+ EI AT AG V GH+ P YAA G DHE T ED Sbjct: 181 MMNFPGVAANDSKMVAEIAATRAAGLTVGGHYASPDLGRAFHAYAAGGPADDHEGTTVED 240 Query: 246 VIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMDFV 305 I RVR GM + +R GSAW DVA + A TE G+DPR +L TDD S +L +GHM+ V Sbjct: 241 AIARVRQGMRSMLRLGSAWFDVAAQVKAITERGIDPRNFVLCTDDSHSGTLVSDGHMNRV 300 Query: 306 VRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMTIA 365 VRHAISQG+KP+TA QMAT+NTA+ FG+ RD+GSI PG AD+I+ +L + + + Sbjct: 301 VRHAISQGLKPITAIQMATLNTAQHFGLERDLGSIAPGRRADLIVTS-DLTALPIEIVFV 359 Query: 366 AGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVIEN 425 G ++AE G++ A + Y YP +V L + DF I A S V RVI VIEN Sbjct: 360 RGRLLAEKGVLVADIPAYDYPASAKNTVKLGKRLAPTDFDICAA-GSSEVEVRVIGVIEN 418 Query: 426 HVETEELILDLPVSEGRLQV--GNGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIAMT 483 T+ L LPV G +Q+ + +C+IA++ERH+ TG +G G+ A+A T Sbjct: 419 QAPTKALQRRLPVECGVVQMDRASDVCQIALVERHRATGGVINAFVSGFGYDTHCAMAST 478 Query: 484 VAHDSHNVLVIGNDDGLMXXXXXXXXXX-XXXXXXXXXXXXXLFPLAIAGLMSVEPFEMX 542 VAHDSH+++V+G + M L L +AGLMS + E+ Sbjct: 479 VAHDSHHMIVVGTNKADMAQAANRLQEVGGGIVLIAGGRELALVELPVAGLMSDQRAEIV 538 Query: 543 XXXXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLVRISPEEGIKLV 597 + GC LN A+M SLLAL VIP LRISD GL+ ++ E +++ Sbjct: 539 AEKASRLVEAMRACGCKLNNAYMQHSLLALVVIPELRISDVGLIDVTRFESTEVI 593 >BH0640 [F] COG1001 Adenine deaminase Length = 585 Score = 290 bits (742), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 205/595 (34%), Positives = 311/595 (52%), Gaps = 38/595 (6%) Query: 8 LADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVSHMIG 67 + D + +A A A L+I G++V+V E EG V + G I + ++ Sbjct: 1 MTDRLERKLAIAANQDKADLLIKNGQIVDVFQLETFEG-DVVIADGEIVAISDPGTY--- 56 Query: 68 EGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVFGLK 127 E ++A G +IAP +DGH HIES+ + +FA+ V+P G T D HEIANV G++ Sbjct: 57 EAHEEVDAKGAFIAPAFIDGHVHIESSMVAPEQFAKVVVPHGVTTVIADPHEIANVAGVQ 116 Query: 128 GIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALGEVM 187 G+ ML+ G PL M V SCVP A P FE +GA + EEVAE + + LGEVM Sbjct: 117 GVEYMLDASEGIPLDVKMMVPSCVP-ATP-FEHSGARLTAEEVAELF-RDPRIFGLGEVM 173 Query: 188 NFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECVTAEDVI 247 ++P V+ D +M+ +++A GR+VDGH D L Y AAG+ DHE VT E+ Sbjct: 174 DYPAVLTRDQEMMAKLKAAHSEGRIVDGHGAG-LDSVALNAYTAAGIGNDHEAVTPEEAK 232 Query: 248 ERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMDFVVR 307 R++ GMY +R G+A D + A T ++ RR L VTDD+ + L +EG +D VR Sbjct: 233 ARLQRGMYLLIREGTAAKDFDALMKAITP--MNSRRALFVTDDKHLDELVEEGSIDHHVR 290 Query: 308 HAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMTIAAG 367 AI GV P+ A QMA++N AE F +A+ G+I PG AD++ ++ +L + + G Sbjct: 291 KAIQIGVNPLQAIQMASLNAAECFKLAKK-GAIAPGFTADLLFIE-DLQSLAITHVFKNG 348 Query: 368 VVVAENGIMTASLAPYAYPGE-VLASVHLP-----QLPVA-----EDFVIRAPIESGSVL 416 VA+NG + + P + +L SV++ QL ++ E +I+ I+ GS++ Sbjct: 349 TCVAKNGKLIVPIRETVQPPQRLLESVNMKLVTKEQLELSLQSDEEAHLIQ--IQPGSIV 406 Query: 417 TRVIRVIENHVETEELILDLPVSEGRLQVGNGLCKIAVLERHKGTGNKSVGVAAGIGFHE 476 T+ IR V ++ + V+ +L K+ V ERH G VG+ G G + Sbjct: 407 TKHIR---EKVAVKDGVFIPSVARDQL-------KLVVAERHHKRGTVGVGIVKGFGLTK 456 Query: 477 PAAIAMTVAHDSHNVLVIG-NDDGLMXXXXXXXXXXXXXXXXXXXXXXXLFPLAIAGLMS 535 AIA TVAHDSHN++ +G ND+ L+ PL I GLMS Sbjct: 457 -GAIATTVAHDSHNIVAVGTNDEDLLAAIKELENIQGGMTIVKDGKVLVSLPLTIGGLMS 515 Query: 536 VEPFEMXXXXXXXXXXXLYDSGCTLNY-AFMTLSLLALAVIPTLRISDKGLVRIS 589 + +++ + G ++ F+TLS LAL VIP ++++D+GL ++ Sbjct: 516 DQSYDVVCEQIKSVDAAIGALGFVGDFNPFLTLSFLALPVIPEIKLTDQGLFDVT 570 >BS_adeC [F] COG1001 Adenine deaminase Length = 577 Score = 281 bits (719), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 207/592 (34%), Positives = 306/592 (51%), Gaps = 27/592 (4%) Query: 11 CVPELVATARGDLPATLVITGGKLVNVCSGE-ILEGMSVAVQGGRIAYVGKDVSHMIGEG 69 V L A+A+ A +VI GK+++V + E I E +A+ G I +G+ EG Sbjct: 6 LVNRLNASAKRQ-KADIVIKNGKIMDVYNQEWIYE--DIAITDGVIVGLGE------YEG 56 Query: 70 TRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVFGLKGI 129 +I+A G+ I PG +DGH HIES+ +T EFA+AVLP G T D HEIANV G KGI Sbjct: 57 ENIIDAEGQMIVPGFIDGHVHIESSMVTPIEFAKAVLPHGVTTVVTDPHEIANVSGEKGI 116 Query: 130 RLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALGEVMNF 189 MLE+ R TPL + + S VP+A FE +GA + ++ Y E+V+ L EVM++ Sbjct: 117 EFMLEQARHTPLNIHFMLPSSVPAAS--FERSGAILKAADLKPFYEE-EEVLGLAEVMDY 173 Query: 190 PGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECVTAEDVIER 249 V + M+ ++ AG+ +DGH + D + +Y A V DHE + E+ ++R Sbjct: 174 VSVQQAEKDMVQKLLDARVAGKRIDGHLAGLSTDL-INIYRTAFVLNDHEVTSKEEALDR 232 Query: 250 VRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMDFVVRHA 309 +R GMY MR GS + + A E P + TDD+ + L EG ++ V+ A Sbjct: 233 IRRGMYVMMREGSVAKNTLNVLPAVNEKNRTP--VFFCTDDKHVDDLLSEGSVNHQVKMA 290 Query: 310 ISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMTIAAGVV 369 I G+ P A+Q+ ++N AE +G+ G+I PG AD++ + +L +V V MT+ G Sbjct: 291 IQAGLNPFLAYQLGSLNAAECYGLDTK-GAIAPGFDADLLFV-SDLENVTVTMTMVKGQT 348 Query: 370 VAENG-IMTASLAPYAYPGE-VLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVIENHV 427 VAE+ + A A P + +L SV L +DF PI+S + VI++I N + Sbjct: 349 VAEDSKAVYQDHASTAAPDQALLDSVKLAAPLNKQDF--HMPIDSEQQIN-VIQIIPNQL 405 Query: 428 ETEELILDLPVS-EGRLQVGNGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIAMTVAH 486 ET + + PV+ E L KIAV+ERHKG +GV G GF + AIA T++H Sbjct: 406 ETRLVQVPAPVAREFEPDTELDLLKIAVVERHKGLKETGLGVVKGFGF-KSGAIATTISH 464 Query: 487 DSHNVLVIG-NDDGLMXXXXXXXXXXXXXXXXXXXXXXXLFPLAIAGLMSVEPFEMXXXX 545 DSHN++ +G ND+ + PL IAGL+S + E Sbjct: 465 DSHNIIAVGTNDEDIAAAVNKLQEIGGGLTIIKNGEELHSVPLPIAGLLSDQSAEQVNQS 524 Query: 546 XXXXXXXLYDSGCTLNYA-FMTLSLLALAVIPTLRISDKGLVRISPEEGIKL 596 L G T + F+TLS LAL VIP ++++ GL + + I L Sbjct: 525 LLTLHDKLSLIGFTGGFNPFLTLSFLALPVIPDIKMTTTGLFDVKSFQHISL 576 >AGc4165 [F] COG1001 Adenine deaminase Length = 133 Score = 270 bits (691), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 0/588 (0%), Positives = 0/588 (0%), Gaps = 29/588 (4%) Query: 5 RKPLADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVSH 64 A ++ A + + + V Sbjct: 9 AYYDAFNRQDMDAFLALLHDEVVHDINQGERQTGKAAFASF-MDHMNRCYRENLTDMV-- 65 Query: 65 MIGEGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVF 124 + E + + N + Sbjct: 66 ---IMASEDGKRASAEFVVNGEYLKTDEGLPEANGQKYVLPAGAFFDLKDGKVSRVTNYY 122 Query: 125 GLKGIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALG 184 Sbjct: 123 --- 179 Query: 185 EVMNFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECVTAE 244 Sbjct: 180 --- 236 Query: 245 DVIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMDF 304 Sbjct: 237 -- 294 Query: 305 VVRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMTI 364 Sbjct: 295 -- 352 Query: 365 AAGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVIE 424 Sbjct: 353 --------- 403 Query: 425 NHVETEELILDLPV--SEGRLQVGNGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIAM 482 Sbjct: 404 - 462 Query: 483 TVAHDSHNVLVIG-NDDGLMXXXXXXXXXXXXXXXXXXXXXXXLFPLAIAGLMSVEPFEM 541 Sbjct: 463 522 Query: 542 XXXXXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLVRIS 589 Sbjct: 523 570 >SMc01533 [F] COG1001 Adenine deaminase Length = 565 Score = 270 bits (689), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 204/588 (34%), Positives = 299/588 (50%), Gaps = 35/588 (5%) Query: 8 LADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVSHMIG 67 +++ + L+ G PA +V+ GG+ ++ +GE++ +A+ G RI D Sbjct: 1 MSEALERLIDQGVGREPADIVLKGGRFFDLVTGELV-ASDIAISGERIVGTCGDY----- 54 Query: 68 EGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVFGLK 127 EG I+ GR + PG +D H HIES+ +T EF R VLPLG T D HEIANV G + Sbjct: 55 EGREEIDVTGRIVVPGFIDTHLHIESSLVTPHEFDRCVLPLGITTVVCDPHEIANVLGTE 114 Query: 128 GIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALGEVM 187 GI+ L+ T + +Q++SCVP+ ET+GA + P + VI L E M Sbjct: 115 GIQYFLDSAMETVMDIRVQLSSCVPAT--HLETSGADL-PVGRLTPFRHHPKVIGLAEFM 171 Query: 188 NFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWR---LPVYAAAGVTGDHECVTAE 244 NFPGVV D L ++ A DGH A R L Y AAG+ DHEC +AE Sbjct: 172 NFPGVVNKDPVCLAKLDA------FQDGHIDGHAPLLRGKELNGYLAAGIRTDHECTSAE 225 Query: 245 DVIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMDF 304 + +E++R GM+ +R GS D+ + TE L P + L TDDR+ + ++GH+D Sbjct: 226 EALEKIRKGMHILVREGSVSKDLQALMPILTER-LSP-YLALCTDDRNPLDIAEQGHLDN 283 Query: 305 VVRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMTI 364 ++R AIS GV+P+ ++ A+I+ A FG+ RD G + PG AD++++D +L + + + Sbjct: 284 MIRTAISAGVEPLAIYRAASISAARAFGL-RDRGLVAPGWRADLVIVD-SLENCKAELVL 341 Query: 365 AAGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVIE 424 +AG V + + A P G L SV ++ A DF + P G T V+ V+ Sbjct: 342 SAGRRVTD--ALFAGRKPVEPVG--LDSVKAREVKAA-DFGL--PYNEGE--TSVLGVLP 392 Query: 425 NHVETEELILDLPVSEGR--LQVGNGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIAM 482 + TE LP R + + + K+AV+ERH GN + G G G + AIA Sbjct: 393 GKIITEHRRYRLPAEGNRTGVDLDRDIIKVAVIERHGVNGNHANGFVQGFGLKK-GAIAS 451 Query: 483 TVAHDSHNVLVIG-NDDGLMXXXXXXXXXXXXXXXXXXXXXXXLFPLAIAGLMSVEPFEM 541 TV HDSHN+ V+G NDD + L +AGLMS+EP+E Sbjct: 452 TVGHDSHNICVVGVNDDDMALAVNRLGEIKGGFVVVHDGKVTGEIALPVAGLMSLEPYER 511 Query: 542 XXXXXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLVRIS 589 + G TL F+ L+ L L VIP L+ISD+GLV + Sbjct: 512 VRDTLHHLRQAAFALGATLEEPFLQLAFLPLPVIPHLKISDRGLVDVD 559 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 42,121,651 Number of extensions: 1793015 Number of successful extensions: 10279 Number of sequences better than 1.0e-05: 12 Number of HSP's gapped: 10236 Number of HSP's successfully gapped: 12 Length of query: 601 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 489 Effective length of database: 25,461,023 Effective search space: 12450440247 Effective search space used: 12450440247 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 119 (50.4 bits)