BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0479.0011.p (536 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yunI [TQ] COG2508 Regulator of polyketide synthase expression 157 4e-38 BH0757 [TQ] COG2508 Regulator of polyketide synthase expression 100 1e-20 CAC1426 [TQ] COG2508 Regulator of polyketide synthase expression 81 4e-15 CAC3236 [TQ] COG2508 Regulator of polyketide synthase expression 56 1e-07 BH1994_2 [TQ] COG2508 Regulator of polyketide synthase expression 56 2e-07 >BS_yunI [TQ] COG2508 Regulator of polyketide synthase expression Length = 531 Score = 157 bits (397), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 146/555 (26%), Positives = 254/555 (45%), Gaps = 61/555 (10%) Query: 15 LTVEEALSVYPLSEAKLIAGSKGKHRVIKSVNVMDAPDISDWIKEGEMLLTTAYLIKDSL 74 + + + + + A LIAG G R ++ VN+MDAPDI D++ + E+L+TTAY +KD Sbjct: 1 MNILDVMKIPAFENANLIAGKAGGEREVQHVNMMDAPDIVDFLHKNELLVTTAYHLKDHP 60 Query: 75 EDASALLQTLNRRGSAGLGIKLGRFWDAVPEKLIAEAEKMNFPLIELPFQFTFSDQMNGL 134 S L++ + +RG AGLGIK R+ + +P+++I A+ FP+IELP D +N Sbjct: 61 HQLSELIRQMAKRGCAGLGIKTKRYLEDIPKEIIELADSYAFPIIELPEHIRLGDIVNAT 120 Query: 135 FRAELTRSTSVLQSIMEKQRKLMRFALRSGRSRPLFESVSEVIETPLAVVSARGDVVFNN 194 L ++ LQ + +K + + L + VS++++ P+ ++ ++ + Sbjct: 121 LSHILDMRSNELQQAIYAHKKFTNHIMSGKGLQSLLKKVSDILQLPVLLLDQHAKMLSAS 180 Query: 195 SDNAV-PQLLEGWPWQSRNQRF----RIGDKIGFR-LPLLQGGKCSGYLLYCSI-----D 243 +V + L+G F I D+ + LP+ K GYLL + Sbjct: 181 HQISVETEKLKGTLNTVSGPFFTCFSTISDQKTYSVLPIYNHEKNCGYLLIPDMVQAGDK 240 Query: 244 PLLLPVEESLFIQGAELISYHL--HSGYEDYFEHAGHREFSGLLRLCLNGGMPCAEMAQA 301 L+L +E Q A +IS+ L + + + A + F+ + + E+ Sbjct: 241 GLILTIE-----QAANVISFELLKENALKQFSRRARNEFFNNFIERTFSSD---DEIKNR 292 Query: 302 ASKLEVGLLQAPFQLMLTDTVASGDARQTELHRLKE---------EYLEHPLLRDLNGIH 352 A + ++ Q +A R E E E+LE L H Sbjct: 293 AKEFKLRWDQKYM------CIAGKLDRNDESISFTENQLASDSVFEFLEGELSAFPFPPH 346 Query: 353 VMM--NEGLVSLYPAEPYSP---------EQFRELVNACFG-NLKFDKGYYPRAALSSAK 400 M N G++ + + +S EQF+ V+A F + F +S+ Sbjct: 347 FFMKGNVGIILIEATDSWSEMHASVISFLEQFQTQVSAQFKRTVSF--------GISNIC 398 Query: 401 VKPEGLKEAFAEIKECM--GMFQHWGAHGNVVHYRQLELNLLLGRIPAETMEKYCSSSLR 458 K + +AF E + + G A V H + ++ LL +P E ++K+ +S+L+ Sbjct: 399 QKLIDVPDAFTEASDALQSGHLSRSTAFIQVYHAK--DVPELLRLLPVEDLKKFYNSTLQ 456 Query: 459 GLQSREPDYVREMLHTLEVYLENDGHVNETAKKLFIHRNTATYRIEKLSELLDVDFKKIN 518 L ++ + + +LHTL VYLE ++ETAK+L++HRNT YR+EK ELL K Sbjct: 457 SLAEKQQED-QSLLHTLSVYLETHCQISETAKRLYVHRNTVIYRLEKCEELLGKSLKDPE 515 Query: 519 DLMRLKLVFIFRKML 533 MRL+L ++++ Sbjct: 516 TTMRLRLALRMQRLI 530 >BH0757 [TQ] COG2508 Regulator of polyketide synthase expression Length = 557 Score = 99.8 bits (247), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 57/179 (31%), Positives = 101/179 (56%) Query: 13 MNLTVEEALSVYPLSEAKLIAGSKGKHRVIKSVNVMDAPDISDWIKEGEMLLTTAYLIKD 72 M + V + L + EAK++AG G I+SVN+MDAPDI ++ ++LLTTAY +K+ Sbjct: 4 MAMRVIDVLDLPTFQEAKVVAGENGVSNTIQSVNLMDAPDIVHFLTTDQLLLTTAYSLKN 63 Query: 73 SLEDASALLQTLNRRGSAGLGIKLGRFWDAVPEKLIAEAEKMNFPLIELPFQFTFSDQMN 132 + L++ + +G AGLG+K RF D +P+ ++AEA ++ FP+IELP +++ +N Sbjct: 64 NPNALIELVRHMAEQGCAGLGLKTKRFIDTIPDDVLAEANRLGFPIIELPLRYSLGAMLN 123 Query: 133 GLFRAELTRSTSVLQSIMEKQRKLMRFALRSGRSRPLFESVSEVIETPLAVVSARGDVV 191 L T+ L + R+ L + E ++ ++E P+ +++ R D++ Sbjct: 124 ESLGFILKERTNELNYALTLHREFTNMILSGKGFSQIIEKLAAILEAPVILLNERLDIM 182 Score = 71.2 bits (173), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 35/102 (34%), Positives = 62/102 (60%) Query: 432 YRQLELNLLLGRIPAETMEKYCSSSLRGLQSREPDYVREMLHTLEVYLENDGHVNETAKK 491 YR E+ L IP + ++++ SSL+ L E +++L TL+ +L + ++ETAK Sbjct: 453 YRIKEMTELFKSIPQQKLKEFYQSSLKDLAFPETKEKQDLLETLDSFLNHHCQISETAKS 512 Query: 492 LFIHRNTATYRIEKLSELLDVDFKKINDLMRLKLVFIFRKML 533 +FIHRNT YRI+K E+L +D K ++ ++L++ + +L Sbjct: 513 MFIHRNTVIYRIKKCEEILGIDLKGGHETLQLRMALFMKPLL 554 >CAC1426 [TQ] COG2508 Regulator of polyketide synthase expression Length = 397 Score = 80.9 bits (198), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 36/122 (29%), Positives = 72/122 (59%) Query: 16 TVEEALSVYPLSEAKLIAGSKGKHRVIKSVNVMDAPDISDWIKEGEMLLTTAYLIKDSLE 75 T + L + L + K++AG KG +R+I V V++ P+ S W+K GE++L + IK+++ Sbjct: 4 TCKSVLKLPYLEKIKVVAGEKGLNRIITWVQVVEYPEYSKWLKGGELILISGIAIKNNIN 63 Query: 76 DASALLQTLNRRGSAGLGIKLGRFWDAVPEKLIAEAEKMNFPLIELPFQFTFSDQMNGLF 135 ++ +N R +G+ I +G + +P+++I +++FP+ E+PF+ F D + Sbjct: 64 SLVNFIRDINSRSLSGIVISIGPYIKEIPKEVIEIGNQLDFPIFEIPFEVKFIDVSQSIC 123 Query: 136 RA 137 +A Sbjct: 124 KA 125 Score = 66.6 bits (161), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 38/132 (28%), Positives = 67/132 (50%), Gaps = 1/132 (0%) Query: 406 LKEAFAEIKECMGMFQHWGAHGNVVHYRQLELNLLLGRIPA-ETMEKYCSSSLRGLQSRE 464 K + +E C+ + + + V+ Y +L + L ++ E M+K+ L+ L + Sbjct: 263 FKISVSEAHRCLKVLKLNNDNNTVISYDELGIYKLFFQMDNLEEMKKFYLDVLKKLIDYD 322 Query: 465 PDYVREMLHTLEVYLENDGHVNETAKKLFIHRNTATYRIEKLSELLDVDFKKINDLMRLK 524 E+++TLE+Y++ ++N TA+KLFIHRNT YRI ++ E+ K +N L Sbjct: 323 SKNTTELMNTLEMYIKESTNINRTAEKLFIHRNTLKYRIRRIEEITKCSLKDVNVLFNFD 382 Query: 525 LVFIFRKMLERE 536 +K L E Sbjct: 383 TALKIKKFLTME 394 >CAC3236 [TQ] COG2508 Regulator of polyketide synthase expression Length = 312 Score = 56.2 bits (134), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 69/132 (52%), Gaps = 16/132 (12%) Query: 391 YPRAALSSAKVKPEG--LKEAFAEIKECMGMFQHWGAHGNVVHYRQLELNLLLGRIPAET 448 + + +S +++ + LK+A+ E + +F+ + V+ Y +L L E Sbjct: 171 FCKCVVSFSEISKDNFNLKQAYDNAIEALVLFRRFSLKEEVIDYNKLFL---------ER 221 Query: 449 MEKYCSSSLRG-----LQSREPDYVREMLHTLEVYLENDGHVNETAKKLFIHRNTATYRI 503 M Y ++L+ + + + EML+T++ +++N +++ TAK+LFIHRNT YRI Sbjct: 222 MAYYMDNNLKKKIMYKFKDKFDELDSEMLNTIDEFVKNGLNISNTAKRLFIHRNTLIYRI 281 Query: 504 EKLSELLDVDFK 515 +KL + D K Sbjct: 282 DKLKKETGFDIK 293 >BH1994_2 [TQ] COG2508 Regulator of polyketide synthase expression Length = 313 Score = 55.8 bits (133), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/95 (35%), Positives = 53/95 (55%), Gaps = 10/95 (10%) Query: 441 LGRIPAETM--EKYCSSSLRGLQSREPDYVREMLHTLEVYLENDGHVNETAKKLFIHRNT 498 L PA ++ +K+ L+ Q R D + +TL VYL +G + ET+ +L+IHR++ Sbjct: 220 LKNTPATSLFIDKHLQPLLQYSQGRSTD----LFYTLRVYLNQNGSIKETSDELYIHRSS 275 Query: 499 ATYRIEKLSELLDVDFK----KINDLMRLKLVFIF 529 YR+EK+ LLDVD + N +M KL +F Sbjct: 276 LLYRLEKIETLLDVDLNDSEHRFNLMMAFKLYDLF 310 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,244,755 Number of extensions: 1576153 Number of successful extensions: 2804 Number of sequences better than 1.0e-05: 8 Number of HSP's gapped: 2805 Number of HSP's successfully gapped: 11 Length of query: 536 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 425 Effective length of database: 25,576,357 Effective search space: 10869951725 Effective search space used: 10869951725 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)