BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0476.0042.p (257 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ECs0609 [TK] COG0745 Response regulators consisting of a CheY-li... 110 2e-24 BMEI1329 [TK] COG0745 Response regulators consisting of a CheY-l... 108 1e-23 sll0396 [TK] COG0745 Response regulators consisting of a CheY-li... 104 2e-22 CC2757 [TK] COG0745 Response regulators consisting of a CheY-lik... 102 5e-22 Rv0903c [TK] COG0745 Response regulators consisting of a CheY-li... 99 6e-21 >ECs0609 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 60/169 (35%), Positives = 85/169 (50%), Gaps = 1/169 (0%) Query: 81 GWSLVSDLREQGKRLTVMVLSDGRYXXXXXXXXXXXXNEYMVKPVHTGEFKCRVDNLMXX 140 GW +V LR K + +++L+ ++Y+VKP E RV L+ Sbjct: 59 GWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 Query: 141 XXXXXXXXXXXKVDGLVLDPTRRLVQRDGNELKMTPKEFDLLYYLAMHLGEVCPREEILK 200 D L++D R V R G + +T KEF LL + H GEV PR I Sbjct: 119 GAAVIIESQFQVAD-LMVDLVSRKVTRSGTRITLTSKEFTLLEFFLRHQGEVLPRSLIAS 177 Query: 201 QVWDYHFHPDTNVVDVYIRHIRLKVDKGHKNKLIHTVRGIGYVLRAPEG 249 QVWD +F DTN +DV ++ +R K+D + KLI TVRG+GY+L P+G Sbjct: 178 QVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDG 226 >BMEI1329 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 61/173 (35%), Positives = 89/173 (51%), Gaps = 1/173 (0%) Query: 81 GWSLVSDLREQGKRLTVMVLSDGRYXXXXXXXXXXXXNEYMVKPVHTGEFKCRVDNLMXX 140 G S+V+ LR +G V++LS ++Y+ KP E RV+ ++ Sbjct: 59 GLSVVAGLRAKGMETPVLILSALGEVDDRVTGLRAGGDDYLTKPYAFSELLARVE-VLQR 117 Query: 141 XXXXXXXXXXXKVDGLVLDPTRRLVQRDGNELKMTPKEFDLLYYLAMHLGEVCPREEILK 200 +V L LD +R ++ + P+EF LL YL H G+V R +L+ Sbjct: 118 RSSPREADTIYRVGDLELDRLTHTARRQSVDITLQPREFRLLEYLMRHAGQVVTRTMLLE 177 Query: 201 QVWDYHFHPDTNVVDVYIRHIRLKVDKGHKNKLIHTVRGIGYVLRAPEGAPHA 253 VWDYHF P TNV+DV+I +R K++KG L+HTVRG GY+L+A G A Sbjct: 178 NVWDYHFDPQTNVIDVHISRLRSKIEKGFDEPLLHTVRGAGYMLKAGRGKQSA 230 >sll0396 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 224 Score = 104 bits (259), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 59/180 (32%), Positives = 97/180 (53%), Gaps = 3/180 (1%) Query: 66 PALLIADLNHAAAWAGWSLVSDLREQGKRLTVMVLSDGRYXXXXXXXXXXXXNEYMVKPV 125 P L+I + +G L LRE G R+ +++++ ++Y+VKP Sbjct: 47 PDLIIVN-GALPGMSGLELCRRLREMGSRIPIILITAKDDVEERVMGLDAGADDYIVKPF 105 Query: 126 HTGEFKCRVDNLMXXXXXXXXXXXXXKVDGLVLDPTRRLVQRDGNELKMTPKEFDLLYYL 185 ++ EF R+ + + L + + R +QR + +T KEF+LL YL Sbjct: 106 NSDEFFARIR--VQLRRTHTTSDEVLQFADLRFNRSTREIQRGDRLIDLTAKEFELLDYL 163 Query: 186 AMHLGEVCPREEILKQVWDYHFHPDTNVVDVYIRHIRLKVDKGHKNKLIHTVRGIGYVLR 245 H +V RE+IL++VW Y F D+N+++VYIR++RLK++ + +LI TVRG+GYVLR Sbjct: 164 LSHARQVLTREQILERVWGYDFMGDSNIIEVYIRYLRLKLEAAGEPRLIQTVRGVGYVLR 223 >CC2757 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 223 Score = 102 bits (255), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 57/164 (34%), Positives = 84/164 (51%), Gaps = 1/164 (0%) Query: 81 GWSLVSDLREQGKRLTVMVLSDGRYXXXXXXXXXXXXNEYMVKPVHTGEFKCRVDNLMXX 140 G ++V LR +G + V+ LS ++Y+VKP E RV+ L Sbjct: 59 GVTVVETLRREGDQTPVLFLSALGEVNDRVVGLKAGADDYLVKPYAFPELMARVEAL-SR 117 Query: 141 XXXXXXXXXXXKVDGLVLDPTRRLVQRDGNELKMTPKEFDLLYYLAMHLGEVCPREEILK 200 KV L ++ R V R G E+ + P+EF LL ++ H G+ R +L+ Sbjct: 118 RRETGAVATTLKVGELEMNLINRTVHRQGKEIDLQPREFQLLEFMMRHAGQSVTRTMLLE 177 Query: 201 QVWDYHFHPDTNVVDVYIRHIRLKVDKGHKNKLIHTVRGIGYVL 244 +VW+YHF P TNV+DV+I +R K+DKG ++ TVRG GY L Sbjct: 178 KVWEYHFDPQTNVIDVHISRLRSKIDKGFDRAMLQTVRGAGYRL 221 >Rv0903c [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 236 Score = 99.0 bits (245), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 66/211 (31%), Positives = 99/211 (46%), Gaps = 2/211 (0%) Query: 36 KLQQALQELGVQTAIXXXXXXXXXXXXXVEPALLIADLNHAAAWAGWSLVSDLREQGKRL 95 L++ L+ G + A P ++ D+N G S+V+ LR + Sbjct: 25 SLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPV-LDGVSVVTALRAMDNDV 83 Query: 96 TVMVLSDGRYXXXXXXXXXXXXNEYMVKPVHTGEFKCRVDNLMXXXXXXXXXXXXXKVDG 155 V VLS ++Y+VKP E RV L+ G Sbjct: 84 PVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVG 143 Query: 156 -LVLDPTRRLVQRDGNELKMTPKEFDLLYYLAMHLGEVCPREEILKQVWDYHFHPDTNVV 214 L +D R + +G ++ +T +EFDLL LA H V R ++L+ VW Y F DTNVV Sbjct: 144 PLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVV 203 Query: 215 DVYIRHIRLKVDKGHKNKLIHTVRGIGYVLR 245 DV+I ++R K++ G +L+HTVRG+G+VLR Sbjct: 204 DVFIGYLRRKLEAGGGPRLLHTVRGVGFVLR 234 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.139 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,262,167 Number of extensions: 551514 Number of successful extensions: 2841 Number of sequences better than 1.0e-05: 176 Number of HSP's gapped: 2802 Number of HSP's successfully gapped: 176 Length of query: 257 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 153 Effective length of database: 26,383,695 Effective search space: 4036705335 Effective search space used: 4036705335 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 114 (48.5 bits)