BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0476.0040.p (497 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC3339 [R] COG0488 ATPase components of ABC transporters with d... 481 e-135 BS_yfmM [R] COG0488 ATPase components of ABC transporters with d... 473 e-133 SP0770 [R] COG0488 ATPase components of ABC transporters with du... 445 e-125 SPy1206 [R] COG0488 ATPase components of ABC transporters with d... 431 e-120 L101706 [R] COG0488 ATPase components of ABC transporters with d... 406 e-113 >CAC3339 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 518 Score = 481 bits (1238), Expect = e-135, Method: Compositional matrix adjust. Identities = 237/448 (52%), Positives = 308/448 (68%), Gaps = 1/448 (0%) Query: 1 MSLLTVEDVSHNFGDRQLFKNVSFRLLAGEHVGLVGANGVGKSTLMNILTGKLLKDSGRV 60 MS+L V++V+H FGDR +F++VSFRLL GEHVGLVGANG GKST M+I+TGKL+ D G + Sbjct: 1 MSILNVKNVNHGFGDRAIFEDVSFRLLKGEHVGLVGANGEGKSTFMSIITGKLMPDEGTI 60 Query: 61 EWTPKVRYGYLDQHTLLTPGKTIRDVLKDAFLPLLELENEMMAITGKMGEADPXXXXXXX 120 EW+ VR GY+DQH L GKTI+DVLKDAF L ++E MM IT KM EA Sbjct: 61 EWSNNVRVGYMDQHASLQKGKTIKDVLKDAFKYLFDMEANMMEITDKMAEASEDELQKLL 120 Query: 121 XXXXXXXXXXDIGDFYLIDVKVEEMGNGLGLSAIGLDRDVSTLSGGQRTXXXXXXXXXXX 180 D DFY+IDVK+EE+ GLG++ IGLD+DV+ LSGGQRT Sbjct: 121 DEMGTIQDTLDNNDFYVIDVKIEEVAKGLGITDIGLDKDVADLSGGQRTKVLLAKLLLQK 180 Query: 181 XXXXXXDEPTNYLDVEHFDWLTNYLKQYPYAFILISHDTEFMNKVVGVVYHLEFAKLTRY 240 DEPTNYLD H +WL YL + AFILISHD F+N V+ V+YH++ KLTRY Sbjct: 181 PDILLLDEPTNYLDEVHIEWLKRYLNDFENAFILISHDIPFLNSVINVIYHIDNRKLTRY 240 Query: 241 TANYERFLEMADMNKIQHIDAYEKQQEFIKKQEDFIQRNKARASTSGRAKSREKQLDRME 300 +Y+ F+ + + NK Q AYE+QQ+ I K +DF+ RNKAR +T+G A++R+KQLD+M+ Sbjct: 241 AGDYDNFMRVYEANKKQVEAAYERQQQEIAKLKDFVARNKARVATTGMARARQKQLDKMD 300 Query: 301 RIDRPEEAAKPSFSFKESRASGKTVFEGLDFEIGYDRPLLPKLNMTIERGEKIAIVGCNG 360 I++ +E KP F+FK +R SGK +FE D +GYD PL LN+T+ERG+KIA+VG NG Sbjct: 301 IIEKTQEKPKPEFNFKTARTSGKLIFETKDLVVGYDSPLSKPLNLTMERGQKIALVGANG 360 Query: 361 IGKSTLLKTILGVIPAYSGKTYLGDYLNAAYFQQEVKAAN-LTPIDDVWNEFSSLNQHEV 419 +GK+TLLK++LG I SG LGDY YF+QE+K AN T I++VW EF + Q+EV Sbjct: 361 LGKTTLLKSLLGKIKPISGDVELGDYQYIGYFEQEIKEANDKTCIEEVWEEFPAYTQYEV 420 Query: 420 RAHLARCGLKNEHITRPLSMLSGGEQAK 447 RA LA+CGL +HI + +LSGGEQAK Sbjct: 421 RAALAKCGLTTKHIESKVMVLSGGEQAK 448 >BS_yfmM [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 518 Score = 473 bits (1218), Expect = e-133, Method: Compositional matrix adjust. Identities = 238/448 (53%), Positives = 304/448 (67%), Gaps = 1/448 (0%) Query: 1 MSLLTVEDVSHNFGDRQLFKNVSFRLLAGEHVGLVGANGVGKSTLMNILTGKLLKDSGRV 60 MS+L+V+D+SH FGDR +F NVSFRLL GEHVGL+GANG GKST MNI+TGKL D G+V Sbjct: 1 MSILSVKDLSHGFGDRAIFNNVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLEPDEGKV 60 Query: 61 EWTPKVRYGYLDQHTLLTPGKTIRDVLKDAFLPLLELENEMMAITGKMGEADPXXXXXXX 120 EW+ VR GYLDQHT+L GK+IRDVLKDAF L +E EM I KMGEADP Sbjct: 61 EWSKNVRVGYLDQHTVLEKGKSIRDVLKDAFHYLFAMEEEMNEIYNKMGEADPDELEKLL 120 Query: 121 XXXXXXXXXXDIGDFYLIDVKVEEMGNGLGLSAIGLDRDVSTLSGGQRTXXXXXXXXXXX 180 DFY+ID KVEE+ GLGLS IGL+RDV+ LSGGQRT Sbjct: 121 EEVGVIQDALTNNDFYVIDSKVEEIARGLGLSDIGLERDVTDLSGGQRTKVLLAKLLLEK 180 Query: 181 XXXXXXDEPTNYLDVEHFDWLTNYLKQYPYAFILISHDTEFMNKVVGVVYHLEFAKLTRY 240 DEPTNYLD +H +WL YL++Y AFILISHD F+N V+ ++YH+E +LTRY Sbjct: 181 PEILLLDEPTNYLDEQHIEWLKRYLQEYENAFILISHDIPFLNSVINLIYHVENQELTRY 240 Query: 241 TANYERFLEMADMNKIQHIDAYEKQQEFIKKQEDFIQRNKARASTSGRAKSREKQLDRME 300 +Y +F+E+ ++ K Q AY+KQQ+ + + +DF+ RNKAR ST A SR+K+LD+M+ Sbjct: 241 VGDYHQFMEVYEVKKQQLEAAYKKQQQEVAELKDFVARNKARVSTRNMAMSRQKKLDKMD 300 Query: 301 RIDRPEEAAKPSFSFKESRASGKTVFEGLDFEIGYDRPLLPKLNMTIERGEKIAIVGCNG 360 I+ E KP F FK +R SGK +FE D IGYD PL LN+ +ERG+KIA+ G NG Sbjct: 301 MIELAAEKPKPEFHFKPARTSGKLIFETKDLVIGYDSPLSRPLNLRMERGQKIALYGANG 360 Query: 361 IGKSTLLKTILGVIPAYSGKTYLGDYLNAAYFQQEVKAA-NLTPIDDVWNEFSSLNQHEV 419 IGK+TLLK++LG I G G+++ YF+QEVK N T I++VW+EF S Q+E+ Sbjct: 361 IGKTTLLKSLLGEIQPLEGSVERGEHIYTGYFEQEVKETNNNTCIEEVWSEFPSYTQYEI 420 Query: 420 RAHLARCGLKNEHITRPLSMLSGGEQAK 447 RA A+CGL +HI +S+LSGGE+AK Sbjct: 421 RAAPAKCGLTTKHIESRVSVLSGGEKAK 448 >SP0770 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 513 Score = 445 bits (1144), Expect = e-125, Method: Compositional matrix adjust. Identities = 221/448 (49%), Positives = 297/448 (66%), Gaps = 2/448 (0%) Query: 1 MSLLTVEDVSHNFGDRQLFKNVSFRLLAGEHVGLVGANGVGKSTLMNILTGKLLKDSGRV 60 MS+L V+++SH FGDR +F++VSFRLL GEH+GLVGANG GKST M+I+TGK+L D G+V Sbjct: 1 MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKSTFMSIVTGKMLPDEGKV 60 Query: 61 EWTPKVRYGYLDQHTLLTPGKTIRDVLKDAFLPLLELENEMMAITGKMGEADPXXXXXXX 120 EW+ V GYLDQH++L +++RDVL+ AF L + E + + KM E D Sbjct: 61 EWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARINDLYMKMAE-DGADVDALM 119 Query: 121 XXXXXXXXXXDIGDFYLIDVKVEEMGNGLGLSAIGLDRDVSTLSGGQRTXXXXXXXXXXX 180 + DFY +D K++E+ LG+ G+D DV++LSGGQRT Sbjct: 120 EEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVTSLSGGQRTKVLLAKLLLEK 179 Query: 181 XXXXXXDEPTNYLDVEHFDWLTNYLKQYPYAFILISHDTEFMNKVVGVVYHLEFAKLTRY 240 DEPTNYLD EH DWL YL+ Y AF+LISHD F+N V+ +VYH+E +LTRY Sbjct: 180 PDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDIPFLNDVINIVYHVENQQLTRY 239 Query: 241 TANYERFLEMADMNKIQHIDAYEKQQEFIKKQEDFIQRNKARASTSGRAKSREKQLDRME 300 + +Y +F E+ M K Q AYE+QQ+ I +DF+ RNKAR +T A SR+K+LD+M+ Sbjct: 240 SGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVARNKARVATRNMAMSRQKKLDKMD 299 Query: 301 RIDRPEEAAKPSFSFKESRASGKTVFEGLDFEIGYDRPLLPKLNMTIERGEKIAIVGCNG 360 I+ E KPSF FK +R G+ +F+ + +IGYDRPL LN+T ER +K+AI+G NG Sbjct: 300 IIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGYDRPLTKPLNLTFERNQKVAIIGANG 359 Query: 361 IGKSTLLKTILGVIPAYSGKTYLGDYLNAAYFQQEVKAAN-LTPIDDVWNEFSSLNQHEV 419 IGK+TLLK++LG+I +G+ GDYL YF+QEV+ N TP++ VWN F +LNQ EV Sbjct: 360 IGKTTLLKSLLGIISPIAGEVERGDYLELGYFEQEVEGGNRQTPLEAVWNAFPALNQAEV 419 Query: 420 RAHLARCGLKNEHITRPLSMLSGGEQAK 447 RA LARCGL +HI + +LSGGEQAK Sbjct: 420 RAALARCGLTTKHIESQIQVLSGGEQAK 447 >SPy1206 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 521 Score = 431 bits (1107), Expect = e-120, Method: Compositional matrix adjust. Identities = 218/449 (48%), Positives = 290/449 (64%), Gaps = 3/449 (0%) Query: 1 MSLLTVEDVSHNFGDRQLFKNVSFRLLAGEHVGLVGANGVGKSTLMNILTGKLLKDSGRV 60 MS+L V+ +SH FGDR +F+NVSFRLL GEH+GLVGANG GKST M+I+TG L D G+V Sbjct: 8 MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKSTFMSIVTGHLQPDEGKV 67 Query: 61 EWTPKVRYGYLDQHTLLTPGKTIRDVLKDAFLPLLELENEMMAITGKMGEADPXXXXXXX 120 EW+ V GYLDQHT+L G+T+RDVL+ AF L + EN + I M + D Sbjct: 68 EWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRINEIYASMAD-DKADIAVLM 126 Query: 121 XXXXXXXXXXDIGDFYLIDVKVEEMGNGLGLSAIGLDRDVSTLSGGQRTXXXXXXXXXXX 180 + DFY +D K++E+ LG+ G++ DV++LSGGQRT Sbjct: 127 EEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVTSLSGGQRTKVLLAKLLLEK 186 Query: 181 XXXXXXDEPTNYLDVEHFDWLTNYLKQYPYAFILISHDTEFMNKVVGVVYHLEFAKLTRY 240 DEPTN+LD EH +WL YL+ Y AF+LISHD F+N V+ +VYH+E L RY Sbjct: 187 PDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDISFLNDVINIVYHVENQSLVRY 246 Query: 241 TANYERFLEMADMNKIQHIDAYEKQQEFIKKQEDFIQRNKARASTSGRAKSREKQLDRME 300 T +Y +F + +M + Q AYE+QQ+ I +DF+ RNKAR +T A SR+K+LD+M+ Sbjct: 247 TGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVNRNKARVATRNMAMSRQKKLDKMD 306 Query: 301 RIDRPEEAAKPSFSFKESRASGKTVFEGLDFEIGYDRPLLPK-LNMTIERGEKIAIVGCN 359 I+ E KP+F FK++R + +F+ + IGYD PL + LN+T ER +KIAIVG N Sbjct: 307 IIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGYDYPLTKEPLNITFERNQKIAIVGAN 366 Query: 360 GIGKSTLLKTILGVIPAYSGKTYLGDYLNAAYFQQEVKAAN-LTPIDDVWNEFSSLNQHE 418 GIGKSTLLK++LGVI G GD+L YF+QEV N TP++ VW+ F +LNQ E Sbjct: 367 GIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYFEQEVTGVNRQTPLEVVWDAFPALNQAE 426 Query: 419 VRAHLARCGLKNEHITRPLSMLSGGEQAK 447 VRA LARCGL ++HI + +LSGGEQAK Sbjct: 427 VRAALARCGLTSKHIESQIQVLSGGEQAK 455 >L101706 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 517 Score = 406 bits (1043), Expect = e-113, Method: Compositional matrix adjust. Identities = 211/448 (47%), Positives = 282/448 (62%), Gaps = 2/448 (0%) Query: 1 MSLLTVEDVSHNFGDRQLFKNVSFRLLAGEHVGLVGANGVGKSTLMNILTGKLLKDSGRV 60 MS+L V+++SH FGDR +F++VSFRLL GEH+G VGANG GKST MNI+TG L+ D G+V Sbjct: 1 MSILNVKNLSHGFGDRAIFEDVSFRLLKGEHIGFVGANGEGKSTFMNIITGTLVPDEGKV 60 Query: 61 EWTPKVRYGYLDQHTLLTPGKTIRDVLKDAFLPLLELENEMMAITGKMGEADPXXXXXXX 120 W+ K R GY+DQH +L GKT R+ L +AF L ++E ++ KM E Sbjct: 61 IWSKKHRVGYMDQHAVLGKGKTTREALAEAFQYLFDIEAQINDTYMKMAEMSEDEMNAAL 120 Query: 121 XXXXXXXXXXDIGDFYLIDVKVEEMGNGLGLSAIGLDRDVSTLSGGQRTXXXXXXXXXXX 180 D DFYLID KVEE GLGL+ + LD+DV+ LSGGQRT Sbjct: 121 ENVGELQEELDNSDFYLIDAKVEETARGLGLTPL-LDKDVAELSGGQRTKILLGKLLLEK 179 Query: 181 XXXXXXDEPTNYLDVEHFDWLTNYLKQYPYAFILISHDTEFMNKVVGVVYHLEFAKLTRY 240 DEPTNYLD EH WL NYLK Y AFILISHD FM++VV ++YH+ +TRY Sbjct: 180 PDILLLDEPTNYLDEEHILWLKNYLKNYENAFILISHDVPFMDEVVNIIYHVHGLGITRY 239 Query: 241 TANYERFLEMADMNKIQHIDAYEKQQEFIKKQEDFIQRNKARASTSGRAKSREKQLDRME 300 + Y F + + K Q + Q K +DFI R KA +TSG+AK+REK+L +ME Sbjct: 240 SMGYAEFERVFEEKKAQLESLHNAQVAEQAKLKDFIARKKANVATSGQAKAREKKLAKME 299 Query: 301 RIDRPEEAAKPSFSFKESRASGKTVFEGLDFEIGYDRPLLPKLNMTIERGEKIAIVGCNG 360 ++ E KP F FK SR + VFE D IGY+ PL ++N+ +E G+KIA +G NG Sbjct: 300 IVETISEKPKPHFDFKFSRKPSRLVFEAKDLVIGYNEPLSSEINLKVESGQKIAFIGSNG 359 Query: 361 IGKSTLLKTILGVIPAYSGKTYLGDYLNAAYFQQEVK-AANLTPIDDVWNEFSSLNQHEV 419 IGKSTLLK+++G+IP+ G+ G++ + AY++QE+K + T +DD+W+E+ S NQ E+ Sbjct: 360 IGKSTLLKSLMGLIPSLDGEVEKGNFQDIAYYEQEIKNPSQKTVLDDLWDEYPSWNQAEL 419 Query: 420 RAHLARCGLKNEHITRPLSMLSGGEQAK 447 R LAR GL + I + +LSGGEQAK Sbjct: 420 RGALARVGLTAKQIESRVYVLSGGEQAK 447 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 34,181,279 Number of extensions: 1305763 Number of successful extensions: 30607 Number of sequences better than 1.0e-05: 234 Number of HSP's gapped: 30150 Number of HSP's successfully gapped: 347 Length of query: 497 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 386 Effective length of database: 25,576,357 Effective search space: 9872473802 Effective search space used: 9872473802 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)