BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0476.0012.p (429 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0527 [E] COG0624 Acetylornithine deacetylase/Succinyl-diamino... 278 8e-75 lin1334 [R] COG2262 GTPases 262 9e-70 lin0756 [R] COG2262 GTPases 244 2e-64 AGc2676 [R] COG2262 GTPases 174 2e-43 VNG1275Gm [R] COG2262 GTPases 170 5e-42 >STM0527 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Length = 204 Score = 278 bits (712), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 0/384 (0%), Positives = 0/384 (0%), Gaps = 9/384 (2%) Query: 36 SLQELVQLAETAGVIVLDVLRQNKETPDSKWFIGKGKVEELRMAADGLGANTAIFDQELS 95 S E V+ + +A L + D + + A + A S Sbjct: 15 SHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQS 74 Query: 96 GAQVRNLEEALDLKIIDRTQLILDIFAGRAKTREGIIQVELAQLSYLLPRLSGHGKNLSR 155 Q+ +++ + + + +E + + G ++ + Sbjct: 75 DEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNSIGQ 134 Query: 156 LXXXXXXXXXXESKLETDRRHIRDRISELKRQLDEVVKTRELHRERRRKSGAVQVALVGY 215 R + EL R+ + + + ++ ++ Sbjct: 135 DRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDIRESVAEL 194 Query: 216 TNAGKSTLLKQLTDADVYIENQLFATLDPTSRVLQLPAGKEVVLTDTVGFIQNLPHDLVA 275 Sbjct: 195 254 Query: 276 SFRATLEEVNEANLVLHVVDASSPMREEQMEVVQSILQDLGAAGKPQIVLFNKSDICRPE 335 Sbjct: 255 314 Query: 336 QLQMLP-SGPGFLKISA---FNPDDLT-RITEMIADELAGDTLTFRIPGDR-GDLSSLLY 389 Sbjct: 315 -- 372 Query: 390 RVGEVLEQNVEDNDVLYQVRLNKE 413 Sbjct: 373 - 395 >lin1334 [R] COG2262 GTPases Length = 407 Score = 262 bits (669), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 145/320 (45%), Positives = 202/320 (63%), Gaps = 3/320 (0%) Query: 36 SLQELVQLAETAGVIVLDVLRQNKETPDSKWFIGKGKVEELRMAADGLGANTAIFDQELS 95 S+ EL LA+TA V+D L Q E FIG GK+ EL + A+ IF+ ELS Sbjct: 24 SMSELHSLAKTANGEVMDELIQKLERVSQTSFIGSGKLMELSELVEMHEADVVIFNSELS 83 Query: 96 GAQVRNLEEALDLKIIDRTQLILDIFAGRAKTREGIIQVELAQLSYLLPRLSGHGKNLSR 155 QVRN+ + +D +IIDRTQLILDIFA RAK++EG +QV AQ YLLPRLSG G +LS+ Sbjct: 84 ATQVRNISKIVDARIIDRTQLILDIFAMRAKSKEGKLQVAYAQYKYLLPRLSGQGASLSK 143 Query: 156 LXXXXXXXXXXESKLETDRRHIRDRISELKRQLDEVVKTRELHRERRRKSGAVQVALVGY 215 L ESKLE D+RHIR+++ ++K QL V + R+ +RR + L+GY Sbjct: 144 LGGGIGSRGPGESKLEMDKRHIREKMHDIKAQLTHVERHRKRIIDRRNTQSVFRFGLIGY 203 Query: 216 TNAGKSTLLKQLTDADVYIENQLFATLDPTSRVLQLPAGKEVVLTDTVGFIQNLPHDLVA 275 TNAGKST+ +LT+ E++LFATLDPT+R ++ G + +LTDTVGFIQ+LP L+A Sbjct: 204 TNAGKSTIFNRLTNETTLEEDKLFATLDPTTRKIRFEGGFQALLTDTVGFIQDLPTTLIA 263 Query: 276 SFRATLEEVNEANLVLHVVDASSPMREEQMEVVQSILQDLGAAGKPQIVLFNKSDICRPE 335 +FR+TLEE ++++HVVDAS P + V ++L++L + P ++++NK D P Sbjct: 264 AFRSTLEETANVDVLIHVVDASDPDYLQHETTVINLLEELEMSHLPTLIVYNKMDKA-PS 322 Query: 336 QLQMLPSGPGFLKISAFNPD 355 +P P L ISA + D Sbjct: 323 TF--VPDRPEHLLISALDQD 340 >lin0756 [R] COG2262 GTPases Length = 418 Score = 244 bits (622), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 161/424 (37%), Positives = 250/424 (58%), Gaps = 20/424 (4%) Query: 14 DRAILVSLVTDKIKRTGVDPELSLQELVQLAETAGVIVLDVLRQNKETPDSKWFIGKGKV 73 ++ +L+ V+ K K D + S++EL LA + V+ LRQN + + ++GKGKV Sbjct: 2 EKNVLIVGVSQKQK----DFDYSMEELANLAAANNMEVVGELRQNIDRENRATYVGKGKV 57 Query: 74 EELRMAADGLGANTAIFDQELSGAQVRNLEEALDLKIIDRTQLILDIFAGRAKTREGIIQ 133 +E++ A+ A IF+ ELS +Q+RNLEEAL+L+++DRT LIL IFA RAKT+E +Q Sbjct: 58 DEIKGLAEMQDARLIIFNDELSPSQIRNLEEALELEVMDRTGLILAIFANRAKTKEAQLQ 117 Query: 134 VELAQLSYLLPRLSGHGKNLSRLXXX--XXXXXXXESKLETDRRHIRDRISELKRQLDEV 191 V++A+L Y LPR+ G G+++ + E K+ETDRR I+ +I L+++LD + Sbjct: 118 VQIAKLQYELPRIFGQGEDMDQQSGKGGLSNRGSGEKKIETDRRTIKHQIRHLQKELDML 177 Query: 192 VKTRELHRERRRKSGAVQVALVGYTNAGKSTLLKQL-------TDADVYIENQLFATLDP 244 V RE+ R +R+K+ V+LVGYTNAGKST + L D V+ ++ LFATL+ Sbjct: 178 VDDREVRRRKRKKNEIPVVSLVGYTNAGKSTTMNGLVRAYSETADKQVFEKDMLFATLET 237 Query: 245 TSRVLQLPAGKEVVLTDTVGFIQNLPHDLVASFRATLEEVNEANLVLHVVDASSPMREEQ 304 + R + LP K+ +LTDTVGF+ LPH LV +FR+TLEE +A+L++HVVD S P + Sbjct: 238 SVREIVLPDNKQFLLTDTVGFVSKLPHQLVKAFRSTLEEARDADLLIHVVDYSDPHYKTM 297 Query: 305 MEVVQSILQDLGAAGKPQIVLFNKSDICRPEQLQMLPS-GPGFLKISAFNPDDLTRITEM 363 M+ + L+ +G P I +NK+D+ E + P + SA + L +TE+ Sbjct: 298 MKTTEETLKAVGVEDVPVIYAYNKADLIEGE---IYPKQTENTIVFSAREEESLEFLTEV 354 Query: 364 IADEL--AGDTLTFRIPGDRGDLSSLLYRVGEVLEQNVEDNDVLYQVRLNKEDYGKWS-Y 420 I EL + + TF IP + G++ + L +VL +N ++ D K + Y Sbjct: 355 IRKELFASYEKATFLIPFEAGNVVAYLNDHADVLATEYLENGTEIVAEISPADLQKLAEY 414 Query: 421 KLAE 424 ++AE Sbjct: 415 QVAE 418 >AGc2676 [R] COG2262 GTPases Length = 218 Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 16/212 (7%), Positives = 39/212 (18%), Gaps = 8/212 (3%) Query: 167 ESKLETDRRHIRDRISELKRQLDEVVKTRELHRERRRKSGAVQVALVGYTNAGKSTLLKQ 226 R + + + L R A+ + + Sbjct: 6 GRDNPNRIIRSRQSMKQELILASSSASRQMLMRNAGLTFSAIPADIDERALDEQLERDGA 65 Query: 227 LTDADVYIENQLFATLDPTSRVLQLPAGKEVVLTDTVGFIQNLPHDLVASFRATLEEVNE 286 + + A L G + + + A+ Sbjct: 66 SPEEVALELARAKALAVSALHPEALVLGCDQTMALGTRVYHKPKNMAEAATHLLSLSGKV 125 Query: 287 ANLVLHVVDASSPMREEQMEVVQSILQDLG----AAGKPQIVLFNKSDICRPEQ----LQ 338 L V + Q + + Q V Q Sbjct: 126 HRLNSAAVLVHNGKVVWQTVSSAELAVRTLSAEFVSRHLQRVGEKALSSVGAYQLEREGI 185 Query: 339 MLPSGPGFLKISAFNPDDLTRITEMIADELAG 370 L + + L ++++ ++ Sbjct: 186 QLFTSIEGDYFTILGLPLLPLLSKLRDMDVID 217 >VNG1275Gm [R] COG2262 GTPases Length = 435 Score = 170 bits (430), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 126/317 (39%), Positives = 179/317 (56%), Gaps = 27/317 (8%) Query: 33 PELSLQELVQLAETAGVIVLDVLRQNKETPDSKWFIGKGKVEELRMAADGLGANTAIFDQ 92 PE + E+ L + AG ++ + Q++ T D +G GKV EL A+ +FD Sbjct: 20 PETA--EIRDLVQAAGYELVGEVTQSR-TADPALQLGAGKVTELAERVARTDADRVVFDN 76 Query: 93 ELSGAQVRNLEEAL--DLKIIDRTQLILDIFAGRAKTREGIIQVELAQLSYLLPRLSGHG 150 L Q NL + L +++DR +LILDIF RA TR+ +QVELA+L Y LPR Sbjct: 77 RLGPYQTFNLGQELPDGTEVVDRFRLILDIFGQRANTRKAQLQVELAELRYELPRAEAK- 135 Query: 151 KNLSRLXXXXXXXXXXESKLETDRRHIRDRISELKRQLDEVVKTRELHRERRRKSGAVQV 210 +L++ E E+ + I+ RIS ++ +L + KT + RE RR+SG V Sbjct: 136 TSLAKRNERPGFMGLGEYD-ESREQDIKARISRIRDELSNIEKTEQQRRETRRESGFDLV 194 Query: 211 ALVGYTNAGKSTLLKQLT-------------DADVYIENQ--LFATLDPTSRVLQLPAGK 255 AL GYTNAGKSTLL++L D D E+Q LF TL T+R ++L A + Sbjct: 195 ALAGYTNAGKSTLLRRLAADVAVDENDDRHPDLDTTAESQDDLFTTLGTTTRRMEL-ARR 253 Query: 256 EVVLTDTVGFIQNLPHDLVASFRATLEEVNEANLVLHVVDASSPMR--EEQMEVVQSILQ 313 +V+LTDTVGFI +LPH LV SF++TLE V +A+LVL VVDAS P+ +E++ L Sbjct: 254 DVLLTDTVGFISDLPHWLVESFKSTLESVYQADLVLLVVDASEPLADIQEKLATSHDTLY 313 Query: 314 DLGAAGKPQIVLFNKSD 330 + A P + +FNK+D Sbjct: 314 ERNEA--PIVTVFNKTD 328 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.135 0.367 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 29,048,759 Number of extensions: 1201940 Number of successful extensions: 14133 Number of sequences better than 1.0e-05: 8 Number of HSP's gapped: 14135 Number of HSP's successfully gapped: 8 Length of query: 429 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 320 Effective length of database: 25,807,025 Effective search space: 8258248000 Effective search space used: 8258248000 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 117 (49.7 bits)