BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0476.0001.p
         (544 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ML0276 [P] COG0607 Rhodanese-related sulfurtransferase                127   5e-29
STM0524 [F] COG2233 Xanthine/uracil permeases                         120   8e-27
TM0524 [QR] COG0500 SAM-dependent methyltransferases                  120   8e-27
BS_ypiP [QR] COG0500 SAM-dependent methyltransferases                 100   1e-20

>ML0276 [P] COG0607 Rhodanese-related sulfurtransferase
          Length = 695

 Score =  127 bits (319), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 61/160 (38%), Positives = 90/160 (56%)

Query: 79  FPELNYIGQHHGTYIIAQNDSGLYLIDQHAAHERVNYEYYYEKFGRPEDASQELLLPITL 138
           FP+L Y+ Q H TY++ Q+  GLYL+DQHAA ER+ YEY+ +K G      Q LL P   
Sbjct: 490 FPQLEYLAQLHATYLLCQSKEGLYLVDQHAAQERIKYEYWKDKIGEVSMEQQILLAPYLF 549

Query: 139 EFTPSESKQLSERLHWFQQAGVYLEHFGGQTFLVRSLPYWFPEGDEKAVIEEMAEWVLSE 198
               ++   L+E+     +AGV+LE +G   F++R  P W  E + +  I EM + +LS 
Sbjct: 550 TLAKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSINEMIDIILSS 609

Query: 199 RSIDLAKLREKSSILCSCKASIKANQKLTEHEVESLLSRL 238
           +   L K R   + + +CK+SIKAN  L      +LL+ L
Sbjct: 610 KEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAEL 649


>STM0524 [F] COG2233 Xanthine/uracil permeases
          Length = 432

 Score =  120 bits (300), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 9/239 (3%), Positives = 27/239 (11%), Gaps = 8/239 (3%)

Query: 285 NMIITTGFDPIPAIEMRAKSLAERTGTIYTPRGKLSMSKMAERYKDGEILVVLQDAVRLI 344
            +I                               L    +                  L 
Sbjct: 3   PVINRESVLSGFQWFFFIFCNTVVVPPTLLSAFHLPADNLLMLT------QYAFLTTALA 56

Query: 345 TPGMPPMEFHPSMGFVRAKRIIRGEPDPMLEAARMVPGDSVLDCTAGLGSDSLLFAVYGG 404
                    H          +  G    +               ++     ++   V   
Sbjct: 57  CLV-QAFCGHRRAIMEGPTGLWWGAILTITLGEASRGTPLNDIASSLSVGIAISAMVTIF 115

Query: 405 EASTVTXXXXXXXXXXXXXXGMSHYISGQEKVNEALRRVRVVHSDHLAYLREQPDNSIDI 464
                                    + G +  +   + +  +                 +
Sbjct: 116 IGI-SGLGHRLARLFTPAVMVFFMLLLGAQLTSIFFKGMLGLPFGIADTSARIKLAPFGL 174

Query: 465 VYFDPMFRVPLTDSAAISPLRQFXXXXXXXXXXXXXXXXXXXKTVLLKEKALSGEFSRL 523
                 F + +         R                          +           
Sbjct: 175 AVAVMCFILAMIIFLQQRISRYALLVGTVVGWGLWRLCFPSSHLPPGELSWRWFPLGSH 233


>TM0524 [QR] COG0500 SAM-dependent methyltransferases
          Length = 254

 Score =  120 bits (300), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 76/239 (31%), Positives = 117/239 (48%), Gaps = 8/239 (3%)

Query: 285 NMIITTGFDPIPAIEMRAKSLAERTGTIYTPRGKLSMSKMAERYKDGEILVVLQDAVRLI 344
           N ++TT   P     M+AK LAE+ GTIY  R +L   K+   Y      VV ++ + + 
Sbjct: 3   NFVVTTSHKPDREQVMKAKELAEKLGTIYVSRRRLKEFKVDFYY------VVEKNRISIK 56

Query: 345 TPGMPPMEFHPSMGFVRAKRIIRGEPDPMLEAARMVPGDSVLDCTAGLGSDSLLFAVYGG 404
            PG     FHPS   +R + I  G+ D ++E+ +    + VLD T GLGS+++L A +  
Sbjct: 57  WPG-GEFFFHPSSAILRMRNIRSGQKDYLIESLQPEGNEIVLDTTFGLGSEAILMAAFLP 115

Query: 405 EASTVTXXXXXXXXXXXXXXGMSHYISGQEKVNEALRRVRVVHSDHLAYLREQPDNSIDI 464
           E   V               GM ++ +    + +AL+R+ + H++   Y+R QPDNS D+
Sbjct: 116 EGK-VIGLEGSIHIYTIVKYGMENFETDIRWLKDALKRIELYHANFKEYIRSQPDNSFDV 174

Query: 465 VYFDPMFRVPLTDSAAISPLRQFXXXXXXXXXXXXXXXXXXXKTVLLKEKALSGEFSRL 523
           VY DPMF  P+ +S+A++PLR F                   K V+LK       F R+
Sbjct: 175 VYCDPMFENPVYESSAMNPLRPFAVYDTVNEEDIEEMLRIAKKKVILKSHVKDSLFKRI 233


>BS_ypiP [QR] COG0500 SAM-dependent methyltransferases
          Length = 172

 Score = 99.8 bits (247), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 51/154 (33%), Positives = 81/154 (52%)

Query: 373 MLEAARMVPGDSVLDCTAGLGSDSLLFAVYGGEASTVTXXXXXXXXXXXXXXGMSHYISG 432
           ML AA +  GD+ LDCT GLGSD+++ ++  GE  +V               G+  + +G
Sbjct: 1   MLRAAGLSEGDTFLDCTLGLGSDAIIASMAVGETGSVVGIEKNHLVSVLVRTGLHSWETG 60

Query: 433 QEKVNEALRRVRVVHSDHLAYLREQPDNSIDIVYFDPMFRVPLTDSAAISPLRQFXXXXX 492
            E++  A+RR++V + D   ++++ PDNS+D+VYFDPMF  P+  S  I+PLR       
Sbjct: 61  IEELQAAMRRIQVKNGDCFEHIKQLPDNSVDVVYFDPMFHEPVETSDGIAPLRDLAEDSV 120

Query: 493 XXXXXXXXXXXXXXKTVLLKEKALSGEFSRLCFS 526
                         K+V+LK+   S  F +  F+
Sbjct: 121 LHEGCINEAVRVARKSVVLKDHWKSPRFEQFGFN 154


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.319    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 37,010,751
Number of extensions: 1556019
Number of successful extensions: 2388
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 2385
Number of HSP's successfully gapped: 4
Length of query: 544
Length of database: 38,378,431
Length adjustment: 111
Effective length of query: 433
Effective length of database: 25,576,357
Effective search space: 11074562581
Effective search space used: 11074562581
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 118 (50.1 bits)