BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0475.0005.p (238 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC3502 [K] COG2188 Transcriptional regulators 147 1e-35 STM3602 [K] COG2188 Transcriptional regulators 145 4e-35 BS_yurK [K] COG2188 Transcriptional regulators 145 7e-35 ZyhfR [K] COG2188 Transcriptional regulators 137 2e-32 ECs4225 [K] COG2188 Transcriptional regulators 137 2e-32 >CAC3502 [K] COG2188 Transcriptional regulators Length = 237 Score = 147 bits (372), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 87/239 (36%), Positives = 143/239 (59%), Gaps = 6/239 (2%) Query: 2 LNSEQVEPLYIQLKKAVQAAIANGSFNPGDKIPTEIELSATYNVSRITVRKAIEELVSEG 61 LN+ PLY QL+K +Q I +G G ++PTE ELS YNVSR+TVRKA+ EL G Sbjct: 3 LNNTIATPLYKQLEKKLQQEIDSGKRPAGSRLPTENELSKAYNVSRVTVRKALAELSESG 62 Query: 62 YLTKRQGKGTFVNAHKIGRKIEH-IISFTAACRANGLSSHSVITERKKIKADQETAERLQ 120 YL ++ GKGTFV K+ R I + ++ F+ C+ + I + + ++ +++ Sbjct: 63 YLERKSGKGTFVAEKKLERGITNGVLGFSEMCKMMNAIPGAKIIKIALEEPSEKDIQKMS 122 Query: 121 IQQGEPVLYIQRKRYAGERPLMLENNYYPFERFSFLMEESL-EGSVYELLRDRYQIDPNQ 179 + + E VL ++R RYA +P++LE N +P E FSFL EE+L + S+Y++L +++ I + Sbjct: 123 LNKDEKVLVLERVRYANGKPVLLELNKFP-ESFSFLFEENLTDASLYDIL-EQHNIILDH 180 Query: 180 PGETVXXXXTLADEQQAKLLEIPIGQPLFYMNTIIYDQHSKPVHVGKQYIIGDRYQFTL 238 +T+ AD ++AK L I G PL +N+II++ + ++ +Q IGD++ F + Sbjct: 181 SRKTL--DIVFADTKEAKTLGISRGYPLLRINSIIHNADNTITNLCQQLCIGDKFTFII 237 >STM3602 [K] COG2188 Transcriptional regulators Length = 239 Score = 145 bits (367), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 86/237 (36%), Positives = 132/237 (55%), Gaps = 4/237 (1%) Query: 3 NSEQVEPLYIQLKKAVQAAIANGSFNPGDKIPTEIELSATYNVSRITVRKAIEELVSEGY 62 +S+ +PLY QL+ A++ AIA G + PG +IPTE ELS + VSR+TVRKA++ L E Sbjct: 6 DSKSAKPLYKQLEAALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENL 65 Query: 63 LTKRQGKGTFVNAHKIGRKIEHIISFTAACRANGLSSHSVITERKKIKADQETAERLQIQ 122 LT+ GKGTFV+ K R + I+SF+ C++ G S + D ET L + Sbjct: 66 LTRVSGKGTFVSGEKFQRSMTGIMSFSELCQSQGRRPGSRTIKSVFESVDDETKALLNMN 125 Query: 123 QGEPVLYIQRKRYAGERPLMLENNYYPFERFSFLMEESLEG-SVYELLRDRYQIDPNQPG 181 GE + I+R RYA + + LE + P RF+FL++E L S+YE LR++Y + Sbjct: 126 DGEKAVVIERIRYADDVAVSLETVHLP-PRFAFLLDEDLNNHSLYECLREKYHLWFTHSR 184 Query: 182 ETVXXXXTLADEQQAKLLEIPIGQPLFYMNTIIYDQHSKPVHVGKQYIIGDRYQFTL 238 + + A + A L + G PL + + + D + V +Q I+GD+ +FT+ Sbjct: 185 KMI--ELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239 >BS_yurK [K] COG2188 Transcriptional regulators Length = 242 Score = 145 bits (365), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 134/239 (56%), Gaps = 3/239 (1%) Query: 1 MLNSEQVEPLYIQLKKAVQAAIANGSFNPGDKIPTEIELSATYNVSRITVRKAIEELVSE 60 MLN+ PLYIQLK+ + I G ++P K+PTE EL YNVSRITVRKAI +LV E Sbjct: 1 MLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELCTKYNVSRITVRKAILDLVEE 60 Query: 61 GYLTKRQGKGTFVNAHKIGRKIEHIISFTAACRANGLSSHSVITERKKIKADQETAERLQ 120 GYL ++QGKGTFV + K+ R++ + ++ + G + I A + AE+LQ Sbjct: 61 GYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPKHHVLSHDIIPASKPIAEKLQ 120 Query: 121 IQQGEPVLYIQRKRYAGERPLMLENNYYPFERFSFLMEESLEG-SVYELLRDRYQIDPNQ 179 IQ PV+ ++R Y ++PL E +YP + F + +G S++++L+ +Y++ P Sbjct: 121 IQPESPVVELKRILYNDDQPLTFEVTHYPLDLFPGIDTFIADGVSMHDILKQQYKVVPTH 180 Query: 180 PGETVXXXXTLADEQQAKLLEIPIGQPLFYMNTIIYDQHSKPVHVGKQYIIGDRYQFTL 238 T A ++++K L+ IG LF ++ + + +P++ + +R FT+ Sbjct: 181 --NTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQPIYCSLFLMHTNRVTFTI 237 >ZyhfR [K] COG2188 Transcriptional regulators Length = 265 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 128/230 (55%), Gaps = 4/230 (1%) Query: 10 LYIQLKKAVQAAIANGSFNPGDKIPTEIELSATYNVSRITVRKAIEELVSEGYLTKRQGK 69 LY +++ + IA G + G +IPTE EL YNVSRIT+RKAI +LV++G L + QGK Sbjct: 34 LYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGK 93 Query: 70 GTFVNAHKIGRKIEHIISFTAACRANGLSSHSVITERKKIKADQETAERLQIQQGEPVLY 129 GTFV + K+ + + FT + G ++ + E++++ A E+L I V + Sbjct: 94 GTFVQSQKVENALLTVSGFTDFGVSQGKATKEKVIEQERVSA-APFCEKLNIPGNSEVFH 152 Query: 130 IQRKRYAGERPLMLENNYYPFERFSFLMEESLEG-SVYELLRDRYQIDPNQPGETVXXXX 188 + R Y + PL +++++ P R+ E +EG S Y+L ++R+ +T+ Sbjct: 153 LCRVMYLDKEPLFIDSSWIPLSRYPDFDEIYVEGSSTYQLFQERFDTRVVSDKKTIDIFA 212 Query: 189 TLADEQQAKLLEIPIGQPLFYMNTIIYDQHSKPVHVGKQYIIGDRYQFTL 238 A QAK L+ +G+PLF ++ I +DQ+ KPVHV + + +R T+ Sbjct: 213 --ATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTI 260 >ECs4225 [K] COG2188 Transcriptional regulators Length = 265 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 78/230 (33%), Positives = 128/230 (55%), Gaps = 4/230 (1%) Query: 10 LYIQLKKAVQAAIANGSFNPGDKIPTEIELSATYNVSRITVRKAIEELVSEGYLTKRQGK 69 LY +++ + IA G + G +IPTE EL YNVSRIT+RKAI +LV++G L + QGK Sbjct: 34 LYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGK 93 Query: 70 GTFVNAHKIGRKIEHIISFTAACRANGLSSHSVITERKKIKADQETAERLQIQQGEPVLY 129 GTFV + K+ + + FT + G ++ + E+++I A E+L I V + Sbjct: 94 GTFVQSQKVENALLTVSGFTDFGVSQGKATKEKVIEQERISA-APFCEKLNIPGNSEVFH 152 Query: 130 IQRKRYAGERPLMLENNYYPFERFSFLMEESLEG-SVYELLRDRYQIDPNQPGETVXXXX 188 + R Y + PL +++++ P R+ E +EG S Y+L ++R+ +T+ Sbjct: 153 LCRVMYLDKEPLFIDSSWIPLSRYPDFDEIYVEGSSTYQLFQERFDTRVVSDKKTIDIFA 212 Query: 189 TLADEQQAKLLEIPIGQPLFYMNTIIYDQHSKPVHVGKQYIIGDRYQFTL 238 A QAK L+ +G+PLF ++ I +DQ+ KPVHV + + +R T+ Sbjct: 213 --ATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTI 260 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.135 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,441,188 Number of extensions: 655540 Number of successful extensions: 1799 Number of sequences better than 1.0e-05: 159 Number of HSP's gapped: 1704 Number of HSP's successfully gapped: 159 Length of query: 238 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 135 Effective length of database: 26,499,029 Effective search space: 3577368915 Effective search space used: 3577368915 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 114 (48.5 bits)