BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0475.0001.p (224 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-li... 189 4e-48 MT0510 [TK] COG0745 Response regulators consisting of a CheY-lik... 183 2e-46 Rv0491 [TK] COG0745 Response regulators consisting of a CheY-lik... 182 2e-46 ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 179 4e-45 L0125 [TK] COG0745 Response regulators consisting of a CheY-like... 179 4e-45 >Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 189 bits (479), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 100/232 (43%), Positives = 148/232 (63%), Gaps = 12/232 (5%) Query: 1 MPTILVADDDANIRELVSLFLRNDGFQTAEAADGEEALNVYASTQADLVVLDIMMPVMDG 60 M IL+ +D+ ++ + ++ LR +GF T A DG AL ++ + D+V+LD+M+P M G Sbjct: 1 MTRILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSG 60 Query: 61 WTLCKELRRINPDLPLLMLTARGETWEKVKGFELGTDDYLTKPFDPLELTARVRALLKRY 120 +CKELR ++ +P++M+TAR +KV G ELG DDY+TKP+ EL AR+RA+L+R Sbjct: 61 TDVCKELRSVST-VPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRR 119 Query: 121 RIGSA---------QKIQFGNVILDRQTYKVMRGTESLTLPLKEFELLYKLAGTPGQVYT 171 + Q ++ G V +D ++ V G E +++PLKEF+LL L G+V T Sbjct: 120 GVTETEAEELPLDDQILEGGRVRMDVDSHTVTVGGEPVSMPLKEFDLLEYLLRNAGRVLT 179 Query: 172 RGQLIDQIWGIDYAGDDRTIDVHIKRLRERFADTPD--FRIETVRGLGYRLE 221 RGQLID+IWG DY GD +T+DVH+KRLR + + P + TVRGLGY+ E Sbjct: 180 RGQLIDRIWGADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYKFE 231 >MT0510 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 183 bits (464), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 96/228 (42%), Positives = 145/228 (63%), Gaps = 7/228 (3%) Query: 1 MPTILVADDDANIRELVSLFLRNDGFQTAEAADGEEALNVYASTQADLVVLDIMMPVMDG 60 M ++L+ +D+ ++ + ++ LR +GF+ DG AL + AD+V+LD+M+P M G Sbjct: 4 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 63 Query: 61 WTLCKELRRINPDLPLLMLTARGETWEKVKGFELGTDDYLTKPFDPLELTARVRALLKRY 120 +CK+LR +P++M+TAR +KV G ELG DDY+TKP+ EL AR+RA+L+R Sbjct: 64 TDVCKQLR-ARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 122 Query: 121 RIGSAQK----IQFGNVILDRQTYKVMRGTESLTLPLKEFELLYKLAGTPGQVYTRGQLI 176 ++ ++ G V +D + + V +++TLPLKEF+LL L G+V TRGQLI Sbjct: 123 GDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI 182 Query: 177 DQIWGIDYAGDDRTIDVHIKRLRERFADTP--DFRIETVRGLGYRLEA 222 D++WG DY GD +T+DVH+KRLR + P + TVRGLGY+LE Sbjct: 183 DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG 230 >Rv0491 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 182 bits (463), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 96/228 (42%), Positives = 145/228 (63%), Gaps = 7/228 (3%) Query: 1 MPTILVADDDANIRELVSLFLRNDGFQTAEAADGEEALNVYASTQADLVVLDIMMPVMDG 60 M ++L+ +D+ ++ + ++ LR +GF+ DG AL + AD+V+LD+M+P M G Sbjct: 1 MTSVLIVEDEESLADPLAFLLRKEGFEATVVTDGPAALAEFDRAGADIVLLDLMLPGMSG 60 Query: 61 WTLCKELRRINPDLPLLMLTARGETWEKVKGFELGTDDYLTKPFDPLELTARVRALLKRY 120 +CK+LR +P++M+TAR +KV G ELG DDY+TKP+ EL AR+RA+L+R Sbjct: 61 TDVCKQLR-ARSSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG 119 Query: 121 RIGSAQK----IQFGNVILDRQTYKVMRGTESLTLPLKEFELLYKLAGTPGQVYTRGQLI 176 ++ ++ G V +D + + V +++TLPLKEF+LL L G+V TRGQLI Sbjct: 120 GDDDSEMSDGVLESGPVRMDVERHVVSVNGDTITLPLKEFDLLEYLMRNSGRVLTRGQLI 179 Query: 177 DQIWGIDYAGDDRTIDVHIKRLRERFADTP--DFRIETVRGLGYRLEA 222 D++WG DY GD +T+DVH+KRLR + P + TVRGLGY+LE Sbjct: 180 DRVWGADYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLEG 227 >ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Length = 233 Score = 179 bits (453), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 94/229 (41%), Positives = 142/229 (62%), Gaps = 10/229 (4%) Query: 1 MPTILVADDDANIRELVSLFLRNDGFQTAEAADGEEALNVYASTQADLVVLDIMMPVMDG 60 M ILV DD+ I ++V L +GF+ A DGEEAL + Q DL++LD+M+P +DG Sbjct: 1 MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG 60 Query: 61 WTLCKELRRINPDLPLLMLTARGETWEKVKGFELGTDDYLTKPFDPLELTARVRALLKRY 120 + +E+R+ + D P++M++A+ ++KV G ELG DDY+TKPF EL AR++A L+R Sbjct: 61 LDVAREIRKTS-DTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRI 119 Query: 121 RIGSAQ-------KIQFGNVILDRQTYKVMRGTESLTLPLKEFELLYKLAGTPGQVYTRG 173 + A+ ++ GN+ ++ Y + + L L +EFELLY LA G+V TR Sbjct: 120 NVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITRE 179 Query: 174 QLIDQIWGIDYAGDDRTIDVHIKRLRERFADTPDF--RIETVRGLGYRL 220 L++ +WG DY GD RT+DV ++RLRE+ DTP + T RG+GY + Sbjct: 180 NLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYM 228 >L0125 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 233 Score = 179 bits (453), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 94/229 (41%), Positives = 142/229 (62%), Gaps = 10/229 (4%) Query: 1 MPTILVADDDANIRELVSLFLRNDGFQTAEAADGEEALNVYASTQADLVVLDIMMPVMDG 60 M ILV DD+ I ++V L +GF+ A DGEEAL + Q DL++LD+M+P +DG Sbjct: 1 MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG 60 Query: 61 WTLCKELRRINPDLPLLMLTARGETWEKVKGFELGTDDYLTKPFDPLELTARVRALLKRY 120 + +E+R+ + D P++M++A+ ++KV G ELG DDY+TKPF EL AR++A L+R Sbjct: 61 LDVAREIRKTS-DTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRI 119 Query: 121 RIGSAQ-------KIQFGNVILDRQTYKVMRGTESLTLPLKEFELLYKLAGTPGQVYTRG 173 + A+ ++ GN+ ++ Y + + L L +EFELLY LA G+V TR Sbjct: 120 NVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITRE 179 Query: 174 QLIDQIWGIDYAGDDRTIDVHIKRLRERFADTPDF--RIETVRGLGYRL 220 L++ +WG DY GD RT+DV ++RLRE+ DTP + T RG+GY + Sbjct: 180 NLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYM 228 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.140 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,092,738 Number of extensions: 685377 Number of successful extensions: 2406 Number of sequences better than 1.0e-05: 540 Number of HSP's gapped: 1902 Number of HSP's successfully gapped: 543 Length of query: 224 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 121 Effective length of database: 26,499,029 Effective search space: 3206382509 Effective search space used: 3206382509 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 114 (48.5 bits)