BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0472.0022.p (232 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin1414 [TK] COG0745 Response regulators consisting of a CheY-li... 218 8e-57 L0131 [TK] COG0745 Response regulators consisting of a CheY-like... 214 7e-56 ML0131 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr... 214 7e-56 BS_ykoG [TK] COG0745 Response regulators consisting of a CheY-li... 183 2e-46 DR0743 [TK] COG0745 Response regulators consisting of a CheY-lik... 177 1e-44 >lin1414 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 226 Score = 218 bits (554), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 120/225 (53%), Positives = 155/225 (68%), Gaps = 3/225 (1%) Query: 10 MNRILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNG 69 MNRIL++EDEKNLARFIELELQH +Y + D WD NG Sbjct: 1 MNRILIVEDEKNLARFIELELQHENYETAVANDGRAGLELALNEEWDAILLDLMLPHLNG 60 Query: 70 IELCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRTG 129 +E+CRR+RQ KQTP+I+ITARD + D+++GLD GADDYI KPFAIEELLAR+RSLLRR Sbjct: 61 VEVCRRVRQVKQTPIIMITARDSVIDRVSGLDHGADDYIVKPFAIEELLARLRSLLRRVE 120 Query: 130 SLCQGQ---LLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLME 186 + Q L ++L ++ R + + E ++LTKRE+++LL LM+N+ V+TRE L+ Sbjct: 121 NAEQSAKQTTLQYRNLIVEKENRIVKRDEEIIDLTKREYELLLTLMENVNIVLTREVLLN 180 Query: 187 SVWGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIR 231 VWGYETEV+ VVDVY+ YLR KID P E S +QT+RG GYV+R Sbjct: 181 KVWGYETEVETNVVDVYVRYLRNKIDHPDEESYIQTVRGTGYVMR 225 >L0131 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 230 Score = 214 bits (546), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 107/224 (47%), Positives = 148/224 (66%), Gaps = 3/224 (1%) Query: 12 RILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNGIE 71 +IL+IEDEKNLARF+ LEL+H Y+ + + +D +G E Sbjct: 5 KILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFE 64 Query: 72 LCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRT--- 128 + RRLR+EK TP+I++TARD D++ GLD GADDYI KPFAIEELLAR+R+ RR Sbjct: 65 VARRLRKEKDTPIIMMTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHG 124 Query: 129 GSLCQGQLLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLMESV 188 ++ + + +DL +D RT+ + + ++LT+RE+D+LL LMQN+G V+TRE L+ V Sbjct: 125 HAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRREYDLLLTLMQNVGDVVTREHLVSQV 184 Query: 189 WGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIRK 232 WGYE + VVDVYI YLR KID G+ S +QT+RGLGYV+R+ Sbjct: 185 WGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRE 228 >ML0131 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Length = 346 Score = 214 bits (546), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 10/224 (4%), Positives = 27/224 (12%), Gaps = 3/224 (1%) Query: 12 RILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNGIE 71 RI E + + + Sbjct: 5 RIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGL 64 Query: 72 LCRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRT--- 128 + ++ + + + + L+R Sbjct: 65 TETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTD 124 Query: 129 GSLCQGQLLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLMESV 188 + D L + + Sbjct: 125 YLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAF 184 Query: 189 WGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIRK 232 D+ + S L + Sbjct: 185 GVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGV 228 >BS_ykoG [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 228 Score = 183 bits (464), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 92/223 (41%), Positives = 146/223 (65%), Gaps = 3/223 (1%) Query: 12 RILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNGIE 71 IL++EDE+ +AR ++LEL++ YSVT+ + + +G+E Sbjct: 5 HILIVEDEEKIARVLQLELEYEGYSVTIKHNGTEGLDAAAEGGYSLVLLDVMLPGLSGLE 64 Query: 72 LCRRLRQ-EKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRTGS 130 + RRLR+ + QTPVI++TARD + DK+ GLD GA+DY+ KPF IEELLAR+R+ LR+ G+ Sbjct: 65 VLRRLRKTDSQTPVILLTARDSIPDKVTGLDIGANDYVTKPFEIEELLARIRAALRQNGT 124 Query: 131 LCQ--GQLLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLMESV 188 + G L DL+++ R + + + +ELT REFD+L+ ++++ +V+TRE+++ SV Sbjct: 125 KTEDIGTFLTYDDLRVNEKTREVRRGDKEVELTPREFDLLVYMLKHPQQVLTREQILSSV 184 Query: 189 WGYETEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIR 231 WG++ D VVDVYI Y+R K+D P E ++ T+RG+GY I+ Sbjct: 185 WGFDYIGDTNVVDVYIRYIRKKLDYPYEKQLIHTIRGVGYAIK 227 >DR0743 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 225 Score = 177 bits (450), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 95/220 (43%), Positives = 140/220 (63%), Gaps = 2/220 (0%) Query: 13 ILLIEDEKNLARFIELELQHVSYSVTLVQDXXXXXXXXXXXXWDXXXXXXXXXXXNGIEL 72 +L+IEDEK++ARFIELEL Y+ + D D +G+E+ Sbjct: 7 VLVIEDEKDIARFIELELAAEGYATEVAFDGVTGLSKFREVNPDLVILDLMLPVLDGLEV 66 Query: 73 CRRLRQEKQTPVIIITARDGLSDKINGLDSGADDYIAKPFAIEELLARMRSLLRRTGSLC 132 RR+R+ TP+II+TA+DG+ DK+ GLDSGADDY+ KPF+IEELLAR+R+ LRR Sbjct: 67 ARRIRKTSNTPIIILTAKDGIQDKVEGLDSGADDYLIKPFSIEELLARVRAHLRRVNPAV 126 Query: 133 QGQLLVCQDLQLDPLGRTLTKSGEALELTKREFDILLVLMQNMGRVMTREKLMESVWGYE 192 G++ V DL ++ GR + + G +EL+ +EF++L +L +N G+V +R ++ E VW E Sbjct: 127 TGEVRVA-DLVMNLDGREIFRGGRRVELSAKEFELLELLARNPGKVFSRFEIEEKVWP-E 184 Query: 193 TEVDMKVVDVYISYLRGKIDTPGEPSIVQTLRGLGYVIRK 232 VVDVYI YLR K++ GE ++ T+RG+GYV+R+ Sbjct: 185 YTGGSNVVDVYIGYLRRKLEEGGERRLIHTVRGVGYVLRE 224 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.140 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,675,540 Number of extensions: 511189 Number of successful extensions: 1983 Number of sequences better than 1.0e-05: 264 Number of HSP's gapped: 1626 Number of HSP's successfully gapped: 264 Length of query: 232 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 129 Effective length of database: 26,499,029 Effective search space: 3418374741 Effective search space used: 3418374741 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 114 (48.5 bits)