BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0471.0014.p (246 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0450 [TK] COG0745 Response regulators consisting of a CheY-li... 180 2e-45 CAC0524 [TK] COG0745 Response regulators consisting of a CheY-li... 157 2e-38 BH0820 [TK] COG0745 Response regulators consisting of a CheY-lik... 147 2e-35 BS_ycbL [TK] COG0745 Response regulators consisting of a CheY-li... 145 4e-35 Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-li... 143 2e-34 >CAC0450 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 227 Score = 180 bits (456), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 93/223 (41%), Positives = 137/223 (61%), Gaps = 2/223 (0%) Query: 19 MKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSG 78 M +L+VEDD +L+ GI TL + I A+++ ++ K LPDGSG Sbjct: 1 MAKILLVEDDEALSMGIKYTLLSEKFEVIATSSIEEAKEVFNNEKISLVLMDLMLPDGSG 60 Query: 79 LDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKRTA 138 D C ++R+ S +PIIFLTA D E ++V GF+LG DDYITKPF + L +R+ AVL+R + Sbjct: 61 YDLCRELRKNSDIPIIFLTACDEEVNVVMGFDLGADDYITKPFKIKELISRIKAVLRRCS 120 Query: 139 SRGE-DKITLGPLSFDFGKLEFYKNKEQLILSKTELKLLKILVTNPGTILTREQLIDRIW 197 SR E ++ + D L+ YKN ++++L+ ELKLL + + N G L R ++ R+W Sbjct: 121 SREEVSELKSRDVLIDKRTLKAYKNDKEIVLTHMELKLLILFIENSGQTLKRNLILQRLW 180 Query: 198 TQEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGYMW 240 EFVD+N L+V +KRLR K++++ P YI TV G+GY W Sbjct: 181 DISEEFVDDNTLSVYIKRLREKLKEDSKNP-YIVTVRGIGYRW 222 >CAC0524 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 228 Score = 157 bits (397), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 86/227 (37%), Positives = 122/227 (53%), Gaps = 15/227 (6%) Query: 19 MKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSG 78 MK + +VEDD+++ K + L L + A + A L NK LPDG+G Sbjct: 1 MKHIFLVEDDKAIAKNLTLLLRSEGFTVNHASTRSDAIGALDGNKFDLALIDISLPDGNG 60 Query: 79 LDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKRTA 138 C +I+ VP+IFLTA+ E +VTG +G DDYITKPF L AR+ L+++ Sbjct: 61 FTVCTEIKEKQDVPVIFLTASGDESSVVTGLNMGADDYITKPFRPRELIARIRTALRKSG 120 Query: 139 SRGEDKITLGPLSFDFGKLE-------FYKNKEQLILSKTELKLLKILVTNPGTILTREQ 191 S P SF+ L K ++ LS E +LL + + N +I+TR + Sbjct: 121 S--------SPSSFEICGLHVDTASGIVKKEGREIFLSALEYRLLLVFINNNKSIITRSR 172 Query: 192 LIDRIWTQEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGY 238 L+D +W EFV++N LTV +KRLR KIE+ PA+P+ I TV G GY Sbjct: 173 LLDELWDAAGEFVNDNTLTVYIKRLREKIENNPASPEIILTVRGTGY 219 >BH0820 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 234 Score = 147 bits (370), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 77/228 (33%), Positives = 126/228 (55%), Gaps = 8/228 (3%) Query: 22 LLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSGLDY 81 +L++EDD S+++ + L + A+D A ++ N LP +G+D Sbjct: 6 ILLIEDDVSISEMVKEHLQLEGYHVCCAFDGEEATRLFEQNTYDLVLLDLMLPRRNGIDC 65 Query: 82 CEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKRTASRG 141 + IR S VP++ ++A D + D G G DDYITKPFS++ L ARV A ++RT + Sbjct: 66 LQWIRTKSVVPVLIMSAKDSDVDKALGLGFGADDYITKPFSMIELTARVKAAIRRTVNYA 125 Query: 142 E-------DKITLGPLSFDFGKLEFYKNKEQLILSKTELKLLKILVTNPGTILTREQLID 194 + ++I + L + K E++ L+ E ++LK+ VT+P + T+EQL Sbjct: 126 QASQSAENERIKIHELVVELSSFTVKKKGEEIKLTAKEFQILKLFVTHPKKVFTKEQLYR 185 Query: 195 RIWTQEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGYMWAE 242 +W + + DEN + V ++RLR KIED P+ P+YIKT++G+GY E Sbjct: 186 SVWNDDY-YSDENVINVHIRRLREKIEDTPSKPQYIKTIWGIGYRMGE 232 >BS_ycbL [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 215 Score = 145 bits (367), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 0/226 (0%), Positives = 0/226 (0%), Gaps = 7/226 (3%) Query: 23 LIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSGLDYC 82 + +L + A + + + Sbjct: 1 MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDDSGLTLMQILLTHGHLD 60 Query: 83 EKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKRTASRGE 142 + E + + + + Sbjct: 61 HVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIG 120 Query: 143 DK------ITLGPLSFDFGKLEFYKNKEQLILSKTELKLLKILVTNPGTILTREQLIDRI 196 + + K + L + Sbjct: 121 NVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGRSDFPRGDHNQLISSIKDKLL 180 Query: 197 WTQEAEFVDENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGYMWAE 242 + Sbjct: 181 PLGDD- 225 >Cgl0399 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 232 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 96/232 (41%), Positives = 127/232 (54%), Gaps = 12/232 (5%) Query: 19 MKTLLIVEDDRSLNKGIALTLAQNDLAIQQAYDITSAEQILSSNKXXXXXXXXHLPDGSG 78 M +LIVED+ SL +A L + A D +A S N+ LP SG Sbjct: 1 MTRILIVEDEESLADPLAFLLRKEGFDTIIAGDGPTALVEFSRNEIDIVLLDLMLPGMSG 60 Query: 79 LDYCEKIRRTSQVPIIFLTANDMEPDIVTGFELGGDDYITKPFSLMILRARVMAVLKR-- 136 D C+++R S VP+I +TA D E D V G ELG DDY+TKP+S L AR+ AVL+R Sbjct: 61 TDVCKELRSVSTVPVIMVTARDSEIDKVVGLELGADDYVTKPYSSRELIARIRAVLRRRG 120 Query: 137 -TASRGE-----DKITLGP-LSFDFGKLEFYKNKEQLILSKTELKLLKILVTNPGTILTR 189 T + E D+I G + D E + + E LL+ L+ N G +LTR Sbjct: 121 VTETEAEELPLDDQILEGGRVRMDVDSHTVTVGGEPVSMPLKEFDLLEYLLRNAGRVLTR 180 Query: 190 EQLIDRIWTQEAEFV-DENALTVAVKRLRTKIEDEPAAPKYIKTVYGLGYMW 240 QLIDRIW A++V D L V VKRLR+KIE+EP+ P+Y+ TV GLGY + Sbjct: 181 GQLIDRIWG--ADYVGDTKTLDVHVKRLRSKIEEEPSRPRYLVTVRGLGYKF 230 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,294,089 Number of extensions: 566942 Number of successful extensions: 1932 Number of sequences better than 1.0e-05: 261 Number of HSP's gapped: 1664 Number of HSP's successfully gapped: 261 Length of query: 246 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 142 Effective length of database: 26,383,695 Effective search space: 3746484690 Effective search space used: 3746484690 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)