BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0471.0013.p (344 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0451 [T] COG0642 Signal transduction histidine kinase 153 3e-37 SA1322 [T] COG0642 Signal transduction histidine kinase 114 2e-25 MA1957_2 [T] COG0642 Signal transduction histidine kinase 113 3e-25 all0542_3 [T] COG0642 Signal transduction histidine kinase 113 4e-25 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 110 3e-24 >CAC0451 [T] COG0642 Signal transduction histidine kinase Length = 416 Score = 153 bits (387), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 91/274 (33%), Positives = 147/274 (53%), Gaps = 4/274 (1%) Query: 72 MDSVDEMVDRAIHGRE--KMTHFDETSLSSLEHKLWRYIEINKTNEQNLETEKNTIKELI 129 ++ V E + I+G ++ + E L L R I + NL+ EK +K ++ Sbjct: 138 INEVHEGAQKIINGNYSLRLNDYREGELGKLSASFNRMSSIIENTLNNLKEEKIFLKNMM 197 Query: 130 SDISHQTKTPLSSIMMYSQLLAETPELSGNTR-LLLNEIESQSEKLEWLITSLVKLSRLE 188 DISHQ KTPLSS+ ++++LL +T L+E + Q +K+EWLI +L+K++RL+ Sbjct: 198 QDISHQLKTPLSSLKIFNELLLNQNIKDEDTMDEFLHESKKQLDKMEWLIINLLKMARLD 257 Query: 189 AGMITLQSTSGPVIETITRAVSHIYTRAEHKGIDLQIECDPLTRARHDHKWTSEALFNLL 248 AG I ++ + ET+ ++S + K + +E +HD KW EA N++ Sbjct: 258 AGAIDFKNEKRSIEETVCESISLLKPMYTLKNQKVSVESTDKAYFKHDKKWLLEAFSNII 317 Query: 249 ENAVKYTKAGGTIRISAESNEMFTRIDVSDTGIGIQRDELEHIFKRFYRGCSARDYEGIG 308 +N +++T G I+I + + ++ + D G GI +D+L HIF+RFY+G + G Sbjct: 318 KNCIEHTGDNGEIKIHVYRSPIMVKVTIEDNGSGISKDDLPHIFERFYKGKGVYNKSSTG 377 Query: 309 IGLYLTQKIISIQGGFITAASEAGKGTKLT-VFL 341 IGL + + II QGGFIT S GT VFL Sbjct: 378 IGLSMAKSIIENQGGFITVKSAVSAGTIFNIVFL 411 >SA1322 [T] COG0642 Signal transduction histidine kinase Length = 588 Score = 114 bits (285), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 70/238 (29%), Positives = 128/238 (53%), Gaps = 14/238 (5%) Query: 113 TNEQNLETEKNTIKELISDISHQTKTPLSSIMMYSQ-----LLAETPELSGNTRLLLNEI 167 TNE NL+ K K+ I+++SH+ +TP+S + Y++ ++ E E+ + ++L+E Sbjct: 356 TNEHNLDQMK---KDFIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAVVLDE- 411 Query: 168 ESQSEKLEWLITSLVKLSRLEAGMITLQSTSGPVIETITRAVSHIYTRAEHKGIDLQIEC 227 S++L L+ L+ ++R++A +++ P+ + + +A+ G+++ Sbjct: 412 ---SKRLNRLVNELLNVARMDAEGLSVNKEVQPIAALLDKMKIKYRQQADDLGLNMTFNY 468 Query: 228 DPLTRARHDHKWTSEALFNLLENAVKYTKAGGTIRISAESNEMFTRIDVSDTGIGIQRDE 287 +D + L NL++NA +YTK G I I+ + NE + + DTG GI + Sbjct: 469 CKKRVWSYDMDRMDQVLTNLIDNASRYTKPGDEIAITCDENESEDILYIKDTGTGIAPEH 528 Query: 288 LEHIFKRFYRGCSARD--YEGIGIGLYLTQKIISIQGGFITAASEAGKGTKLTVFLPQ 343 L+ +F RFY+ +AR +G G+GL++ + II GG I SE GKGT + LP+ Sbjct: 529 LQQVFDRFYKVDAARTRGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLPK 586 >MA1957_2 [T] COG0642 Signal transduction histidine kinase Length = 270 Score = 113 bits (283), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 74/222 (33%), Positives = 120/222 (54%), Gaps = 7/222 (3%) Query: 127 ELISDISHQTKTPLSSIMMYSQLLAE--TPELSGNTRLLLNEIESQSEKLEWLITSLVKL 184 E I+ +SH+ KTPL+SI+ +S LL E + +LS +N I + L I ++ L Sbjct: 22 EFIATVSHELKTPLNSIIGFSDLLLEDSSGKLSERQARYINNISISGKHLLQFIDDILDL 81 Query: 185 SRLEAGMITLQSTSGPVIETITRAVSHIY-TRAEHKGIDLQIECDPLTRARH-DHKWTSE 242 S++EAG L+ + + I + + ++ R K + L E D ++ + D + Sbjct: 82 SKIEAGKTFLEPENFEFTK-IFKDIEKVFRPRVSGKKLSLNFEVDSGIKSFYADKMMFKQ 140 Query: 243 ALFNLLENAVKYTKAGGTIRISAESNEMFTRIDVSDTGIGIQRDELEHIFKRFYRGCS-- 300 L+NL+ NAVK+T G+I +SA RI V DTGIGI R++++ F+ F + S Sbjct: 141 ILYNLISNAVKFTPEEGSITVSAAKIGNMVRICVKDTGIGISREDMDSFFQPFKQPDSFF 200 Query: 301 ARDYEGIGIGLYLTQKIISIQGGFITAASEAGKGTKLTVFLP 342 R YE G+GL+L ++ + + GG I A S G+G+ + LP Sbjct: 201 KRRYERTGLGLFLVKRFVEMHGGNIQAESVPGEGSSFIIELP 242 >all0542_3 [T] COG0642 Signal transduction histidine kinase Length = 227 Score = 113 bits (282), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 79/221 (35%), Positives = 116/221 (52%), Gaps = 6/221 (2%) Query: 127 ELISDISHQTKTPLSSIMMYSQLLAE--TPELSGNTRLLLNEIESQSEKLEWLITSLVKL 184 E ++ +SH+ +TPL++IM SQLL + L+ + +N I S E L LI ++ L Sbjct: 4 EFLATMSHELRTPLNAIMGLSQLLQQEIVGSLNEKQQEYINCIYSSGEHLLALINDILDL 63 Query: 185 SRLEAGMITLQSTSGPVIETITRAVSHIYTRAEHKGIDLQIECDPLTR-ARHDHKWTSEA 243 S++EAG L VI+ + + RA KG+ L E DP D + + Sbjct: 64 SKVEAGKEELFLIPLLVIDVCNDVLLTVRDRAISKGLKLTQEIDPEANICIADDRRIKQM 123 Query: 244 LFNLLENAVKYTKAGGTIRISAESNEMFTRIDVSDTGIGIQRDELEHIFKRFYRGCS--A 301 L NLL NA+K+T G I E I +SDTGIGI ++ +F+ F + S Sbjct: 124 LLNLLTNAIKFTSVGEVSLIVKRVPEGINFI-ISDTGIGIDSNQFPLLFEPFKQLDSRLN 182 Query: 302 RDYEGIGIGLYLTQKIISIQGGFITAASEAGKGTKLTVFLP 342 R YEG G+GL LT+K+ + GG +T S G G++ T+FLP Sbjct: 183 RQYEGTGLGLALTRKLARLHGGDVTVTSTVGVGSQFTLFLP 223 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 110 bits (275), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 12/221 (5%), Positives = 31/221 (14%), Gaps = 6/221 (2%) Query: 126 KELISDISHQTKTPLSSIMMYSQ-LLAETPELSGNTRLLLNEIESQSEKLEWLITSLVKL 184 + ++ TP + L N + + + Sbjct: 52 RLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRSGAESLPDAV 111 Query: 185 SRLEAGMITLQSTSGPVIETITRAVSHIYTRAEHKGIDLQIEC--DPLTRARHDHKWTSE 242 R + + Sbjct: 112 VLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKT-RDFSRPLNLVLN 170 Query: 243 ALFNLLENAVKYTKAGGTIRISAESNEMFTRIDVSDTGIGIQRDELEHIFKRFYR--GCS 300 +L + YT + + + + + + + Sbjct: 171 TGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMN 230 Query: 301 ARDYEGIGIGLYLTQKIISIQGGFITAASEAGKGTKLTVFL 341 + EG L Q Sbjct: 231 EQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPT 271 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.133 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,709,598 Number of extensions: 883679 Number of successful extensions: 2675 Number of sequences better than 1.0e-05: 243 Number of HSP's gapped: 2255 Number of HSP's successfully gapped: 243 Length of query: 344 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 237 Effective length of database: 26,037,693 Effective search space: 6170933241 Effective search space used: 6170933241 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)