BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0471.0008.p (315 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1203 [GER] COG0697 Permeases of the drug/metabolite transport... 72 1e-12 STM1990 [GER] COG0697 Permeases of the drug/metabolite transport... 71 2e-12 ZyedA [GER] COG0697 Permeases of the drug/metabolite transporter... 71 2e-12 yedA [GER] COG0697 Permeases of the drug/metabolite transporter ... 71 2e-12 ECs2697 [GER] COG0697 Permeases of the drug/metabolite transport... 71 2e-12 >YPO1203 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Length = 296 Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 44/91 (48%), Positives = 61/91 (67%), Gaps = 3/91 (3%) Query: 190 MSTAAQMLTGGVLLLIFSYFTSDWSKLDIPAISLRSYAALGYLIVFGSIIGYTAYIWLLK 249 MS AAQML GV+LL+ S + + +L P ++ AL YLIVFGS++ +AY++LLK Sbjct: 182 MSGAAQMLVAGVVLLLASTLSGE--ELQQPP-TMSGILALLYLIVFGSMLAISAYMFLLK 238 Query: 250 NADAALVSTYAFVNPVVAVFFGWLLAGEQLT 280 N A+ ++YA+VNPVVAV G AGE L+ Sbjct: 239 NVRPAVATSYAYVNPVVAVLLGIGFAGESLS 269 Score = 53.1 bits (126), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 41/63 (65%) Query: 16 ALVSVYLFWGGTYVGMKVAIETMPPFLMAGIRFFVAGAVLYIISRLSGAKRPAGREWRSS 75 +L ++Y WG TY+ +++ +E+ PP +MAG+R+ +AG +L+ + G P R+W ++ Sbjct: 15 SLFTLYFVWGSTYLVIRIGVESWPPLMMAGLRYLIAGVLLFSFLAIRGHALPTLRQWAAA 74 Query: 76 AIV 78 + + Sbjct: 75 SAI 77 >STM1990 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Length = 306 Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 41/93 (44%), Positives = 63/93 (67%), Gaps = 5/93 (5%) Query: 189 LMSTAAQMLTGGVLLLIFSYFTSDWSKL-DIPAISLRSYAALGYLIVFGSIIGYTAYIWL 247 +M+ A +ML GV+LL ++ + + KL +P +S + A+GYL +FGSII AY++L Sbjct: 178 MMAGAIEMLAAGVVLLCAAFLSGE--KLATLPGLS--GFMAVGYLALFGSIIAINAYMYL 233 Query: 248 LKNADAALVSTYAFVNPVVAVFFGWLLAGEQLT 280 ++N AL ++YA+VNPVVAV G L GE+L+ Sbjct: 234 IRNVSPALATSYAYVNPVVAVLLGTGLGGERLS 266 Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 23/56 (41%), Positives = 35/56 (62%) Query: 16 ALVSVYLFWGGTYVGMKVAIETMPPFLMAGIRFFVAGAVLYIISRLSGAKRPAGRE 71 AL ++Y+ WG TY +++ +E+ PP +MAG+RF AG +L L G K P R+ Sbjct: 12 ALFALYIIWGSTYFVIRIGVESWPPLMMAGVRFLSAGMLLMAFLLLRGEKLPPLRQ 67 >ZyedA [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Length = 306 Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 43/93 (46%), Positives = 61/93 (65%), Gaps = 5/93 (5%) Query: 189 LMSTAAQMLTGGVLLLIFSYFTSDWSKLD-IPAISLRSYAALGYLIVFGSIIGYTAYIWL 247 +M+ A +ML GV+L+I S + KL +P SL + A+GYL +FGSII AY++L Sbjct: 178 MMAGAIEMLAAGVVLMIASMIAGE--KLTALP--SLSGFLAVGYLALFGSIIAINAYMYL 233 Query: 248 LKNADAALVSTYAFVNPVVAVFFGWLLAGEQLT 280 ++N AL ++YA+VNPVVAV G L GE L+ Sbjct: 234 IRNVSPALATSYAYVNPVVAVLLGTGLGGETLS 266 >yedA [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Length = 306 Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 43/93 (46%), Positives = 61/93 (65%), Gaps = 5/93 (5%) Query: 189 LMSTAAQMLTGGVLLLIFSYFTSDWSKLD-IPAISLRSYAALGYLIVFGSIIGYTAYIWL 247 +M+ A +ML GV+L+I S + KL +P SL + A+GYL +FGSII AY++L Sbjct: 178 MMAGAIEMLAAGVVLMIASMIAGE--KLTALP--SLSGFLAVGYLALFGSIIAINAYMYL 233 Query: 248 LKNADAALVSTYAFVNPVVAVFFGWLLAGEQLT 280 ++N AL ++YA+VNPVVAV G L GE L+ Sbjct: 234 IRNVSPALATSYAYVNPVVAVLLGTGLGGETLS 266 >ECs2697 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Length = 306 Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 43/93 (46%), Positives = 61/93 (65%), Gaps = 5/93 (5%) Query: 189 LMSTAAQMLTGGVLLLIFSYFTSDWSKLD-IPAISLRSYAALGYLIVFGSIIGYTAYIWL 247 +M+ A +ML GV+L+I S + KL +P SL + A+GYL +FGSII AY++L Sbjct: 178 MMAGAIEMLAAGVVLMIASMIAGE--KLTALP--SLSGFLAVGYLALFGSIIAINAYMYL 233 Query: 248 LKNADAALVSTYAFVNPVVAVFFGWLLAGEQLT 280 ++N AL ++YA+VNPVVAV G L GE L+ Sbjct: 234 IRNVSPALATSYAYVNPVVAVLLGTGLGGETLS 266 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.325 0.137 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,290,826 Number of extensions: 558943 Number of successful extensions: 1543 Number of sequences better than 1.0e-05: 12 Number of HSP's gapped: 1538 Number of HSP's successfully gapped: 18 Length of query: 315 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 209 Effective length of database: 26,153,027 Effective search space: 5465982643 Effective search space used: 5465982643 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 116 (49.3 bits)