BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0459.0002.p (349 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value aq_035_2 [T] COG2199 FOG: GGDEF domain 130 4e-30 aq_265_2 [T] COG2199 FOG: GGDEF domain 122 8e-28 mll9509 [T] COG3706 Response regulator containing a CheY-like re... 114 3e-25 BH2234 [T] COG3706 Response regulator containing a CheY-like rec... 112 1e-24 AGc2387 [T] COG3706 Response regulator containing a CheY-like re... 105 8e-23 >aq_035_2 [T] COG2199 FOG: GGDEF domain Length = 251 Score = 130 bits (326), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 64/169 (37%), Positives = 102/169 (60%), Gaps = 2/169 (1%) Query: 182 QNIIMDRLSKVDPLTELYNHKTFHEYLGWLIEHQQSNPFPMQLAVLDIDNFKKVNDQYGH 241 + + +R++ DPLT LYN + F E + + + + ++DIDNFKK+ND YGH Sbjct: 76 EKTLYERMALTDPLTGLYNRRVFTEMAEKELAKAKRYGYNFSILMIDIDNFKKINDTYGH 135 Query: 242 WVGDIVLRQVAGIVLKHIGADDFAARYGGEEFVVILTAKPLEDSRRIMTQILHGIAALPV 301 VGD+VL++++ I+ +++ D AR+GGEEF+V+L+ L + + Q+ I P+ Sbjct: 136 DVGDLVLKKISEILKRNVRGADLVARFGGEEFIVMLSNTNLNGAVKKAEQLRRMIEQTPI 195 Query: 302 AEMDGNS--VTVSIGMHDYAGTDSKSSTFQQADDALYEAKKTGKNKIVV 348 +G VTVSIG+ Y G +S ++AD ALYEAK+ GKN++ V Sbjct: 196 ELPNGEKLRVTVSIGVSTYRGHESLEELIKEADQALYEAKRKGKNRVEV 244 >aq_265_2 [T] COG2199 FOG: GGDEF domain Length = 168 Score = 122 bits (306), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 64/160 (40%), Positives = 96/160 (60%), Gaps = 3/160 (1%) Query: 191 KVDPLTELYNHKTFHEYLGWLIEHQQSNPFPMQLAVLDIDNFKKVNDQYGHWVGDIVLRQ 250 KVDPLT L N + L ++E P +A++DIDNFKK+ND YGH GD VL++ Sbjct: 8 KVDPLTGLLNRRVLPYILRDVLELSLYTETPFSIAMVDIDNFKKINDTYGHLFGDKVLKE 67 Query: 251 VAGIVLKHIGADDFAARYGGEEFVVILTAKPLEDSRRIMTQILHGIAALPVAEMDGN-SV 309 VA I+ K++ D+ RYGGEEF++++ + L+D+ RI+ +I + P+ V Sbjct: 68 VAKIIKKNLRRSDYVFRYGGEEFLILMPSTELKDAVRILEKIRKEVENTPICWQGKEIRV 127 Query: 310 TVSIGMHD--YAGTDSKSSTFQQADDALYEAKKTGKNKIV 347 T+S+G+ Y G S + AD+ LY AK+TGKN++V Sbjct: 128 TISVGVCSDVYNGLKSPEEYIKCADEKLYLAKRTGKNRVV 167 >mll9509 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Length = 354 Score = 114 bits (284), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 64/178 (35%), Positives = 104/178 (58%), Gaps = 4/178 (2%) Query: 174 KSEQDLRIQNIIMDRLSKVDPLTELYNHKTFHEYLGWLIEHQQSNPFPMQLAVLDIDNFK 233 +S++ L N+ ++RL+++D LT L N + F EYL + P+ L ++D DNFK Sbjct: 173 ESQRQLISANLELERLTRIDGLTGLGNRRYFDEYLAAEWKRAFRAQSPLSLLMIDADNFK 232 Query: 234 KVNDQYGHWVGDIVLRQVAGIVLKHIG-ADDFAARYGGEEFVVILTAKPLEDSRRIMTQI 292 + ND YGH GD VL+Q+A ++ G + D AARYGGEEFV++L LE+S I Q+ Sbjct: 233 RYNDTYGHMAGDEVLKQIARVIHSGSGRSTDLAARYGGEEFVIVLVDTLLEESSAIAEQL 292 Query: 293 LHGIAALPVAEMDGNSVTVSIGMHDYAGTDSKSST--FQQADDALYEAKKTGKNKIVV 348 + G+ L + + VT+S+G+ ++++ AD AL+ AK G+N++ + Sbjct: 293 VQGVRELNIPH-GPDRVTISVGVATTVPNENETPNDFVNAADLALFRAKSEGRNRVAL 349 >BH2234 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Length = 314 Score = 112 bits (280), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 66/187 (35%), Positives = 103/187 (55%), Gaps = 5/187 (2%) Query: 167 QSLESSLK--SEQDLRIQNII--MDRLSKVDPLTELYNHKTFHEYLGWLIEHQQSNPFPM 222 + LE +K EQ+ +++ I +DRLS+VD LT L N + E + I + Sbjct: 125 KRLEQHVKVLEEQNEKLKGKIQKVDRLSRVDFLTNLMNRRDMQEKIRAEINRSIRHGRSF 184 Query: 223 QLAVLDIDNFKKVNDQYGHWVGDIVLRQVAGIVLKHIGADDFAARYGGEEFVVILTAKPL 282 LA++DID FK +ND YGH GD VL+ + + + D+ +R+GGEEF+++ L Sbjct: 185 TLAIVDIDFFKNINDTYGHDCGDHVLKHFVSTLKNSVRSSDYVSRWGGEEFLLLFPETKL 244 Query: 283 EDSRRIMTQILHGIAALPVAEMDGN-SVTVSIGMHDYAGTDSKSSTFQQADDALYEAKKT 341 E+ +R +I I PV + S+T + G+ +Y + + ADDALY+ KKT Sbjct: 245 EEGKRACEKIRQKINESPVIYKGMSISITATFGISEYRPSVRIEELIKAADDALYKGKKT 304 Query: 342 GKNKIVV 348 GKN++VV Sbjct: 305 GKNQVVV 311 >AGc2387 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Length = 218 Score = 105 bits (263), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 0/163 (0%), Positives = 0/163 (0%), Gaps = 4/163 (2%) Query: 189 LSKVDPLTELYNHKTFHEYLGWLIEHQQSNPFPMQLAVLDIDNFKKVNDQYGHWVGDIVL 248 Sbjct: 290 349 Query: 249 RQVAGIVLKHIGADDFAARYGGEEFVVILTAKPLEDSRRIMTQILHGIAALP--VAEMDG 306 Sbjct: 350 409 Query: 307 N-SVTVSIGMHDYAGT-DSKSSTFQQADDALYEAKKTGKNKIV 347 Sbjct: 410 452 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.138 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,737,781 Number of extensions: 838459 Number of successful extensions: 2049 Number of sequences better than 1.0e-05: 139 Number of HSP's gapped: 1936 Number of HSP's successfully gapped: 139 Length of query: 349 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 242 Effective length of database: 26,037,693 Effective search space: 6301121706 Effective search space used: 6301121706 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 116 (49.3 bits)