BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0450.0030.p (226 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_resD [TK] COG0745 Response regulators consisting of a CheY-li... 191 6e-49 lin2062 [TK] COG0745 Response regulators consisting of a CheY-li... 189 3e-48 SP1227 [TK] COG0745 Response regulators consisting of a CheY-lik... 182 4e-46 SA1323 [TK] COG0745 Response regulators consisting of a CheY-lik... 181 6e-46 BS_phoP [TK] COG0745 Response regulators consisting of a CheY-li... 177 1e-44 >BS_resD [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 240 Score = 191 bits (486), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 104/231 (45%), Positives = 150/231 (64%), Gaps = 11/231 (4%) Query: 3 KVLVVDDDANIRELVRLYLEDEGIEVVQKGNGAEALEYAENYPPDLVVLDIMMPGMDGWA 62 K+LVVDD+A IR L+R+YLE E + + NG EA+ DL++LD+MMPG DG Sbjct: 8 KILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIAKGLEANYDLILLDLMMPGTDGIE 67 Query: 63 LCARLRELGDMPVLMITAKGEPADRIKGFKLGTDDYLVKPFDPMELALRVKALLKR---- 118 +C ++RE P++M+TAKGE A+R++GF+ GTDDY+VKPF P E+ LRVKALL+R Sbjct: 68 VCRQIREKKATPIIMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLRRASQT 127 Query: 119 -YRIAYSQT---IRLGDLRLDRKSYQVVNKDGLELTLPMKEFELLYKLGSYPGQLFTRNH 174 Y A + T + L +D +++ V DG E++L K +ELLY L P +++ R Sbjct: 128 SYFNANTPTKNVLVFSHLSIDHDAHR-VTADGTEVSLTPKVYELLYFLAKTPDKVYDREK 186 Query: 175 LIAEIWGIDYEGDERTVDVHIKRLRERF--AGHESDFRIVTLRGLGYRLEV 223 L+ E+W ++ GD RTVD H+KRLRE+ E+ +IVT+ G+GY+ EV Sbjct: 187 LLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPEAAKKIVTVWGVGYKFEV 237 >lin2062 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 238 Score = 189 bits (480), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 101/234 (43%), Positives = 151/234 (64%), Gaps = 11/234 (4%) Query: 3 KVLVVDDDANIRELVRLYLEDEGIEVVQKGNGAEALEYAENYPPDLVVLDIMMPGMDGWA 62 +VLVVDD+ IR L+++YLE E + + +G +AL A N ++++LD+MMPG DG Sbjct: 6 RVLVVDDEDRIRRLLKMYLERENYRIEEASDGDQALNMALNNNYEVILLDLMMPGKDGIE 65 Query: 63 LCARLRELGDMPVLMITAKGEPADRIKGFKLGTDDYLVKPFDPMELALRVKALLKRYRIA 122 +C LRE PV+M+TAKGE A+R++GF++G DDY+VKPF P E+ LRVKA+L+R + + Sbjct: 66 VCRELREYKSTPVVMLTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKAVLRRAKQS 125 Query: 123 YSQT--------IRLGDLRLDRKSYQVVNKDGLELTLPMKEFELLYKLGSYPGQLFTRNH 174 + I L++D ++++V+ DG E+ L KE++LLY L P ++F R Sbjct: 126 SEEAAGGTPGDIITFPHLKIDNEAHRVI-VDGKEIGLTPKEYDLLYYLAKSPDKVFDRES 184 Query: 175 LIAEIWGIDYEGDERTVDVHIKRLRERFAGHESDFR--IVTLRGLGYRLEVYRD 226 L+ E+W ++ GD RT+D H+KRLRE+ D IVT+ GLGY+ EV D Sbjct: 185 LLKEVWRYEFFGDLRTIDTHVKRLREKLHDVSEDAARMIVTVWGLGYKFEVPED 238 >SP1227 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 234 Score = 182 bits (462), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 100/229 (43%), Positives = 142/229 (62%), Gaps = 11/229 (4%) Query: 1 MPKVLVVDDDANIRELVRLYLEDEGIEVVQKGNGAEALEYAENYPPDLVVLDIMMPGMDG 60 M K+L+VDD+ I ++++ + EG EVV NG EALE E PD+++LD+M+P +DG Sbjct: 1 MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDG 60 Query: 61 WALCARLRELGDMPVLMITAKGEPADRIKGFKLGTDDYLVKPFDPMELALRVKALLKRYR 120 + +R+ +P+LM++AK D++ G +LG DDY+ KPF EL RVKALL+R + Sbjct: 61 LEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQ 120 Query: 121 I---------AYSQTIRLGDLRLDRKSYQVVNKDGLELTLPMKEFELLYKLGSYPGQLFT 171 + Q I++GDL + +Y V K G EL L +EFELLY L S+ GQ+ T Sbjct: 121 PMPVDGQEADSKPQPIQIGDLEIVPDAY-VAKKYGEELDLTHREFELLYHLASHTGQVIT 179 Query: 172 RNHLIAEIWGIDYEGDERTVDVHIKRLRERFAGHESDFR-IVTLRGLGY 219 R HL+ +WG DY GD RTVDV ++RLRE+ S I+T RG+GY Sbjct: 180 REHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGY 228 >SA1323 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 241 Score = 181 bits (460), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 95/231 (41%), Positives = 141/231 (61%), Gaps = 11/231 (4%) Query: 3 KVLVVDDDANIRELVRLYLEDEGIEVVQKGNGAEALEYAENYPPDLVVLDIMMPGMDGWA 62 ++L+VDD+ IR L+++YLE E E+ + NG EA E A ++LD+M+P MDG Sbjct: 4 EILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMDGIQ 63 Query: 63 LCARLRELGDMPVLMITAKGEPADRIKGFKLGTDDYLVKPFDPMELALRVKALLKRYRIA 122 + +LRE P++M+TAKGE +R++GF+ G DDY+VKPF P E+ LRVKALL+R + Sbjct: 64 VATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRTQST 123 Query: 123 YSQ--------TIRLGDLRLDRKSYQVVNKDGLELTLPMKEFELLYKLGSYPGQLFTRNH 174 + I L +D +++V+ D E+ L KE+ELL L P ++F R Sbjct: 124 TVEQSEPHARDVIEFKHLEIDNDAHRVL-ADNQEVNLTPKEYELLIYLAKTPNKVFDREQ 182 Query: 175 LIAEIWGIDYEGDERTVDVHIKRLRERF--AGHESDFRIVTLRGLGYRLEV 223 L+ E+W ++ GD RTVD H+KRLRE+ E+ I T+ G+GY+ EV Sbjct: 183 LLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEV 233 >BS_phoP [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 223 Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 0/232 (0%), Positives = 0/232 (0%), Gaps = 13/232 (5%) Query: 3 KVLVVDDDANIRELVRLYLEDEGIEVVQKGNGAEALEYAENYPPDLVVLDIMMPGMDGWA 62 V+ + V++ ++ + A+ +V L + Sbjct: 4 LVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLSLI 63 Query: 63 LCARLRELGDM-PVLMITAKGEPADRIKGFKLGTDDYLVKPFDPMELALRVKALLKRYRI 121 R ++ VL + + + + ++ Sbjct: 64 RRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLA 123 Query: 122 AYSQT----------IRLGDLRLDRKSYQVVNKDGLELTLPMKEFELLYKLGSYPGQLFT 171 + + L K E + + Sbjct: 124 SQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIM-ETLIRNNGKVVSKDSLMLQLYPDA 182 Query: 172 RNHLIAEIWGIDYEGDERTVDVHIKRLRERFAGH-ESDFRIVTLRGLGYRLE 222 I + ++ + + + G Sbjct: 183 ELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQG 234 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.144 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,971,015 Number of extensions: 766219 Number of successful extensions: 3666 Number of sequences better than 1.0e-05: 563 Number of HSP's gapped: 3050 Number of HSP's successfully gapped: 566 Length of query: 226 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 123 Effective length of database: 26,499,029 Effective search space: 3259380567 Effective search space used: 3259380567 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 114 (48.5 bits)