BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0450.0020.p (266 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0941 [V] COG1132 ABC-type multidrug transport system, ATPase a... 281 5e-76 SA1683 [V] COG1132 ABC-type multidrug transport system, ATPase a... 270 2e-72 BS_ygaD [V] COG1132 ABC-type multidrug transport system, ATPase ... 269 3e-72 CAC1613 [V] COG1132 ABC-type multidrug transport system, ATPase ... 243 3e-64 DR2379 [V] COG1132 ABC-type multidrug transport system, ATPase a... 240 2e-63 >BH0941 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 584 Score = 281 bits (720), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 143/265 (53%), Positives = 173/265 (65%) Query: 1 MELLNEPYDIIDEXXXXXXXXXXXXIEFQKVWFKYNDENDWVLKNIELSISPGQTVAFVX 60 E ++E YDI+D+ + F V F Y E LK++ + G+TVAFV Sbjct: 320 FEFIDEKYDIVDKEGAVKLEEVHGDVTFDHVSFSYEKEETPALKDVHFHVKRGETVAFVG 379 Query: 61 XXXXXXXXXXXXXPRFYDITEGSLRMDGHDVRTLTQESLRRAVGMVLQDNFLFSGSVRDN 120 PRFYD++ G + +DGHD+R SLR +GMVLQ+N LFS SVR N Sbjct: 380 MSGGGKSTLISLIPRFYDVSSGRILIDGHDIRDYQVRSLRDQIGMVLQENILFSDSVRMN 439 Query: 121 ILFGXXXXXXXXXXXXXXXXXXHDFIMQLPDGYDTEVGERGVKLSGGQKQRVAIARVFLK 180 IL G HDFIM LP+GYDTEVGERGVKLSGGQKQRVAIARVFLK Sbjct: 440 ILMGKPDATEEEVIAAAKAANAHDFIMNLPNGYDTEVGERGVKLSGGQKQRVAIARVFLK 499 Query: 181 DPKVLILDEATSALDLESEHLIQQALQSLASERTTLIVAHRLSTITHADQIVVLEHGEIT 240 +P +LI DEATSALDLESEH IQ+A++ LA RTT IVAHRLSTITHAD+I+V+E+GEI Sbjct: 500 NPPILIFDEATSALDLESEHYIQEAMEKLAKNRTTFIVAHRLSTITHADRIIVVENGEIV 559 Query: 241 ERGTHEELMALDGSYARLFNVQRLD 265 E GTH+ELM+ +G Y +LF VQ LD Sbjct: 560 ESGTHDELMSCNGVYKKLFEVQNLD 584 >SA1683 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 578 Score = 270 bits (689), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 137/264 (51%), Positives = 174/264 (65%) Query: 1 MELLNEPYDIIDEXXXXXXXXXXXXIEFQKVWFKYNDENDWVLKNIELSISPGQTVAFVX 60 +L++E YDI + I+ V F+YND +LK+I LSI G+TVAFV Sbjct: 315 FQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVG 374 Query: 61 XXXXXXXXXXXXXPRFYDITEGSLRMDGHDVRTLTQESLRRAVGMVLQDNFLFSGSVRDN 120 PRFYD+T G + +DGH+++ SLR +G+V QDN LFS +V++N Sbjct: 375 MSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKEN 434 Query: 121 ILFGXXXXXXXXXXXXXXXXXXHDFIMQLPDGYDTEVGERGVKLSGGQKQRVAIARVFLK 180 IL G HDFIM LP GYDTEVGERGVKLSGGQKQR++IAR+FL Sbjct: 435 ILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLN 494 Query: 181 DPKVLILDEATSALDLESEHLIQQALQSLASERTTLIVAHRLSTITHADQIVVLEHGEIT 240 +P +LILDEATSALDLESE +IQ+AL L+ +RTTLIVAHRLSTITHAD+IVV+E+G I Sbjct: 495 NPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIV 554 Query: 241 ERGTHEELMALDGSYARLFNVQRL 264 E GTH EL+A G+Y L+++Q L Sbjct: 555 ETGTHRELIAKQGAYEHLYSIQNL 578 >BS_ygaD [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 165 Score = 269 bits (687), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 0/264 (0%), Positives = 0/264 (0%) Query: 2 ELLNEPYDIIDEXXXXXXXXXXXXIEFQKVWFKYNDENDWVLKNIELSISPGQTVAFVXX 61 Sbjct: 326 385 Query: 62 XXXXXXXXXXXXPRFYDITEGSLRMDGHDVRTLTQESLRRAVGMVLQDNFLFSGSVRDNI 121 Sbjct: 386 445 Query: 122 LFGXXXXXXXXXXXXXXXXXXHDFIMQLPDGYDTEVGERGVKLSGGQKQRVAIARVFLKD 181 Sbjct: 446 505 Query: 182 PKVLILDEATSALDLESEHLIQQALQSLASERTTLIVAHRLSTITHADQIVVLEHGEITE 241 Sbjct: 506 565 Query: 242 RGTHEELMALDGSYARLFNVQRLD 265 Sbjct: 566 589 >CAC1613 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 579 Score = 243 bits (619), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 119/237 (50%), Positives = 165/237 (69%), Gaps = 1/237 (0%) Query: 26 IEFQKVWFKYNDENDWVLKNIELSISPGQTVAFVXXXXXXXXXXXXXXPRFYDITEGSLR 85 I+F+ V FKY+D ++ V+ N+ ++I G+TVA V PRFYD+T GS+ Sbjct: 338 IKFKDVCFKYDDAHE-VIHNLNINIDAGKTVALVGPSGGGKTTICSLLPRFYDVTSGSIT 396 Query: 86 MDGHDVRTLTQESLRRAVGMVLQDNFLFSGSVRDNILFGXXXXXXXXXXXXXXXXXXHDF 145 +D +D+R +T SLR A+G+V QD ++FSG++RDNI +G HD+ Sbjct: 397 IDDNDIRDVTLNSLRNAIGVVQQDVYIFSGTIRDNIAYGRPEASEEEVIEAAKGANIHDY 456 Query: 146 IMQLPDGYDTEVGERGVKLSGGQKQRVAIARVFLKDPKVLILDEATSALDLESEHLIQQA 205 IM L DGYDT VGERGVKLSGGQKQR++IARVFLK+P +LILDEATSALD ESE IQ++ Sbjct: 457 IMSLEDGYDTFVGERGVKLSGGQKQRISIARVFLKNPPILILDEATSALDNESEKYIQKS 516 Query: 206 LQSLASERTTLIVAHRLSTITHADQIVVLEHGEITERGTHEELMALDGSYARLFNVQ 262 L+ L+S RT++++AHRLSTI +AD+I+V++ I E+G HEEL+ G Y+ +N+Q Sbjct: 517 LEKLSSGRTSIVIAHRLSTIRNADEIIVIKDRGIKEKGNHEELLKKGGVYSYYYNMQ 573 >DR2379 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 588 Score = 240 bits (612), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 124/263 (47%), Positives = 166/263 (63%) Query: 2 ELLNEPYDIIDEXXXXXXXXXXXXIEFQKVWFKYNDENDWVLKNIELSISPGQTVAFVXX 61 E++ DI+D +EFQ V F Y+ + VL+++ L I G+ VA V Sbjct: 326 EMMAVTPDIVDAPGAAELQNVRGEVEFQGVSFGYSPDAPPVLRDLNLKIRAGEFVALVGA 385 Query: 62 XXXXXXXXXXXXPRFYDITEGSLRMDGHDVRTLTQESLRRAVGMVLQDNFLFSGSVRDNI 121 PRFYD++ G + +DGHDV +T SLRR+VG+V QD +LFSG+V +NI Sbjct: 386 SGVGKSTLCALIPRFYDVSAGQVLVDGHDVCGVTLASLRRSVGVVQQDVYLFSGTVMENI 445 Query: 122 LFGXXXXXXXXXXXXXXXXXXHDFIMQLPDGYDTEVGERGVKLSGGQKQRVAIARVFLKD 181 +G HDFI +LP GY T++G+RGVKLSGGQKQR++IARVFLKD Sbjct: 446 RYGRPGATEAEAMDAARQAGAHDFITRLPQGYHTDIGQRGVKLSGGQKQRLSIARVFLKD 505 Query: 182 PKVLILDEATSALDLESEHLIQQALQSLASERTTLIVAHRLSTITHADQIVVLEHGEITE 241 P +LI DEATS+LD ESE L+Q++L+ LA RTTL++AHRLST+ +A +IVVL + E Sbjct: 506 PPILIFDEATSSLDNESERLVQESLERLARRRTTLVIAHRLSTVRNAHRIVVLTENGVAE 565 Query: 242 RGTHEELMALDGSYARLFNVQRL 264 G+H EL+AL G YARL + RL Sbjct: 566 EGSHAELLALGGEYARLQALGRL 588 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,130,313 Number of extensions: 475126 Number of successful extensions: 4583 Number of sequences better than 1.0e-05: 1633 Number of HSP's gapped: 3806 Number of HSP's successfully gapped: 1704 Length of query: 266 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 161 Effective length of database: 26,268,361 Effective search space: 4229206121 Effective search space used: 4229206121 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)