BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0448.0003.p (180 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0723 [K] COG1309 Transcriptional regulator 74 2e-13 SP2234 [K] COG1309 Transcriptional regulator 67 2e-11 CAC0724 [K] COG1309 Transcriptional regulator 62 5e-10 L103086 [K] COG1309 Transcriptional regulator 61 8e-10 BH0719 [K] COG1309 Transcriptional regulator 60 2e-09 >CAC0723 [K] COG1309 Transcriptional regulator Length = 185 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 14/159 (8%) Query: 24 LTNTLLVLLRDKPISDISISELCEGAGVGRVSFYRNYTEKEDILKAYIDLLFQSFMDEYH 83 +T +L LL +KP I+I+E+ A +GR +FYRN+ KED+L YI + +DEY Sbjct: 18 ITEAMLKLLAEKPYEKITITEIAYTAQLGRRTFYRNFASKEDVLDMYI----KGLIDEYI 73 Query: 84 NYSEGIERPLSDLIRALFTHIEDHLDFYRLLNERGLVYLLK---DVVVEICGLKPESSKI 140 N + + + + FT HLDF L+ + L++LL + + + + +KI Sbjct: 74 NLLKNEYLTIHNGAKVYFTFWSKHLDFLILMEKNNLLHLLLQRFNQYLPMIHKEVNENKI 133 Query: 141 EAYSKAFVAYTLY----GWVEV---WFQRGMKESATEMA 172 E ++ + Y L+ G+ + W Q G KE+ +MA Sbjct: 134 EKFNDRMLEYVLFFSAGGFWNILVKWLQDGAKETPDDMA 172 >SP2234 [K] COG1309 Transcriptional regulator Length = 180 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 18/182 (9%) Query: 11 MSNQGRNAYVTERLTNTLLVLLRDKPISDISISELCEGAGVGRVSFYRNYTEKEDILKAY 70 M + + N ++ LL ++P IS +L E AG+ R SFY +Y +K D+++ Y Sbjct: 1 MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRSSFYTHYKDKYDMIEHY 60 Query: 71 IDLLFQSFMDEYHNYSEGIERPLSDLIRALFTHIEDHLDFYRLLNERGL----------- 119 LF +F + ++ D I +F ++E LL+E G Sbjct: 61 QSKLFHTFEYIFQKHAHHKR----DAILEVFEYLESEPLLAALLSENGTKEIQNFLRNKL 116 Query: 120 -VYLLKDVVVEICGLKPESSKIEAYSKAFVAYTLYGWVEVWFQRGMKESATEMAD-MFKN 177 + L D+ L ++++E YS ++ + L+G + W G KES+ E+ D + K Sbjct: 117 HIMLSTDLQKRFMQLNLNTTELE-YSSIYLTHALFGVCQTWIAHGKKESSQEITDFLMKM 175 Query: 178 LG 179 LG Sbjct: 176 LG 177 >CAC0724 [K] COG1309 Transcriptional regulator Length = 185 Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 31/177 (17%) Query: 24 LTNTLLVLLRDKPISDISISELCEGAGVGRVSFYRNYTEKEDILKAYIDLLFQSFMDEYH 83 L LL L+R+KP S IS+ E+ + A + R +FYRN+ KED+L Y + LF+ Sbjct: 16 LVQALLDLMREKPYSSISVKEIADRAQLSRRTFYRNFKIKEDLLSEYFNYLFE------- 68 Query: 84 NYSEGIER----PLSDLIRALFTHIEDHLDFYRLLNERGLVYLLKDVVVEICGLKPESSK 139 +Y+E ++ ++D++ F H++ +LL + L YL ++ + P +K Sbjct: 69 DYTESLKELTVLSINDVLITYFEFWNKHINELKLLKQNHLFYL---IMEQANSFIPNINK 125 Query: 140 I-------------EAYSKAFVAYTLYGWVEVWFQRGMKESATEMADM----FKNLG 179 E Y + L+ + W R ++S EMA + F+N Sbjct: 126 FENVKWHDYDNHTEEEYIGLYSIGGLWNVLSNWIDRTDRQSPQEMAQIIIKAFRNFS 182 >L103086 [K] COG1309 Transcriptional regulator Length = 177 Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 19/177 (10%) Query: 11 MSNQGRNAYVTERLTNTLLVLLRDKPISDISISELCEGAGVGRVSFYRNYTEKEDILKAY 70 MSN R +L + ++ LL +K IS +EL + A V R SFY +Y +K D+++AY Sbjct: 1 MSNDSRKDRTKLQLRDAMIQLLGEKSFDQISTTELVKLAKVSRSSFYTHYQDKYDMIEAY 60 Query: 71 IDLLFQSFMDEYHNYSEGIERPLSDLIRALFTHIEDHLDFYRLLNERG-------LVYLL 123 LF++ + + I + + F ++ + + LL+E G ++ L Sbjct: 61 QRRLFETIQYVFEKNNGNIHATMLE----TFEFLKGNQIYAALLSENGSKEIHQFMLQKL 116 Query: 124 KDVVVEICGLKPESSKI------EAYSKAFVAYTLYGWVEVWFQRGMKESATEMADM 174 K+++ P+S + E Y+ + A ++G + W +R KE+ T++A++ Sbjct: 117 KELIQ--SSFFPQSKHLKLGKLGEIYATTYYANAIFGTTQSWIRRKQKETPTQIANL 171 >BH0719 [K] COG1309 Transcriptional regulator Length = 188 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 44/174 (25%), Positives = 85/174 (48%), Gaps = 11/174 (6%) Query: 16 RNAYVTERLTNTLLVLLRDKPISDISISELCEGAGVGRVSFYRNYTEKEDILKAYIDLLF 75 R Y L +L+ L+++KP+S+I+I E+C+ A + R +FY +YT+ D+L D + Sbjct: 8 RKKYTRMLLKESLMKLMQEKPLSNITIKEICDLADINRSTFYSHYTDLYDLLYQIEDEII 67 Query: 76 QSFMDEYHNYSEGIERPLSDLIRALFTHIEDHLDFYR-LLNERG-------LVYLLKDVV 127 + + +Y+ + + L +I ++ + + L +E G ++ L D V Sbjct: 68 KDLSEALSSYNYTKDEEALQMTENLLVYIANNRESCQTLFSEYGDPSFQKKVMMLAHDHV 127 Query: 128 VE--ICGLKPESSKIEAYSKAFVAYTLYGWVEVWFQRGMKESATEMADMFKNLG 179 ++ + G K I Y ++ V+ W + G+K+S EMA++ LG Sbjct: 128 IKTPLVG-KHTKPDISEYVSLYIVNGSIHIVQSWLKNGLKQSPKEMAELIIKLG 180 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 12,969,531 Number of extensions: 469388 Number of successful extensions: 1021 Number of sequences better than 1.0e-05: 9 Number of HSP's gapped: 1020 Number of HSP's successfully gapped: 9 Length of query: 180 Length of database: 38,378,431 Length adjustment: 100 Effective length of query: 80 Effective length of database: 26,845,031 Effective search space: 2147602480 Effective search space used: 2147602480 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 112 (47.8 bits)