BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0443.0025.p (294 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2917 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and rel... 199 4e-51 sll1383 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and rel... 189 3e-48 BMEI0326 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and re... 166 6e-41 mlr3921 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and rel... 161 1e-39 CC3269 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and rela... 157 1e-38 >all2917 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Length = 346 Score = 199 bits (506), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 11/230 (4%), Positives = 34/230 (14%), Gaps = 10/230 (4%) Query: 55 DLVTEVDKGVEQMIRRLILTHYPDHAILGEESVQPGADALTAALEEGRKHEYLWIVDPID 114 + E + G + + + Sbjct: 41 AQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKH----------GSREKLIIASKVSG 90 Query: 115 GTTNFVHGFPFYCVSIALVVKGELTVGVIYDPIRDEMFVAEKGKGAYMHGIPTSVSAEAD 174 + N G ++ L + + + D Sbjct: 91 PSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTD 150 Query: 175 PGSSLVAMGFPPDRTFAQPANMAGLQQILPQIRGIRAGGSAALHLAYVAAGRVDGYWEVG 234 ++ + Q A + + + Sbjct: 151 SAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSL 210 Query: 235 LSPWDCAAGVLLVLESGGKVTDTLGNPYDIGTRHVVASNGRIHDFLLASL 284 L+ + G ++ + T + Sbjct: 211 LNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFS 260 >sll1383 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Length = 287 Score = 189 bits (481), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 101/244 (41%), Positives = 141/244 (57%), Gaps = 10/244 (4%) Query: 42 GRVKELGSKTSAQDLVTEVDKGVEQMIRRLILTHYPDHAILGEESVQPGADALTAALEEG 101 G+V+++ K A DLVTE D+ E +I +I PDHAIL EES Q G Sbjct: 37 GKVQQIQEKGRAGDLVTEADRQAEAIILEIIKRRCPDHAILAEESGQLGQ---------- 86 Query: 102 RKHEYLWIVDPIDGTTNFVHGFPFYCVSIALVVKGELTVGVIYDPIRDEMFVAEKGKGAY 161 + + W +DP+DGTTNF H +P CVSI L+++ TVGV+Y+P R E+F A GA Sbjct: 87 VDNPFCWAIDPLDGTTNFAHSYPVSCVSIGLLIQDIPTVGVVYNPFRQELFRAATSLGAT 146 Query: 162 MHGIPTSVSAEADPGSSLVAMGFPPDRTFAQPANMAGLQQILPQIRGIRAGGSAALHLAY 221 ++ P VS A SL+ GF DR N + +G+R GSAA+ L Sbjct: 147 LNRRPIQVSTTASLDKSLLVTGFAYDRVKTLDNNYPEFCYLTHLTQGVRRSGSAAIDLID 206 Query: 222 VAAGRVDGYWEVGLSPWDCAAGVLLVLESGGKVTDTLGNPYDIGTRHVVASNGRIHDFLL 281 VA GR+DGYWE G++PWD AAG+++V E+GG V+ +P D+ T ++A+NG+IH L Sbjct: 207 VACGRLDGYWERGINPWDMAAGIVIVREAGGIVSAYDCSPLDLSTGRILATNGKIHQELS 266 Query: 282 ASLG 285 +L Sbjct: 267 QALA 270 >BMEI0326 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Length = 346 Score = 166 bits (419), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 16/230 (6%), Positives = 37/230 (16%), Gaps = 10/230 (4%) Query: 55 DLVTEVDKGVEQMIRRLILTHYPDHAILGEESVQPGADALTAALEEGRKHEYLWIVDPID 114 V +M + + E L I + Sbjct: 40 VAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLA----------KHGSREKLIIASKVS 89 Query: 115 GTTNFVHGFPFYCVSIALVVKGELTVGVIYDPIRDEMFVAEKGKGAYMHGIPTSVSAEAD 174 G + ++ E + D + + + + Sbjct: 90 GPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWT 149 Query: 175 PGSSLVAMGFPPDRTFAQPANMAGLQQILPQIRGIRAGGSAALHLAYVAAGRVDGYWEVG 234 + V++ D + L + V Sbjct: 150 DSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYS 209 Query: 235 LSPWDCAAGVLLVLESGGKVTDTLGNPYDIGTRHVVASNGRIHDFLLASL 284 L G+ V + G + + Sbjct: 210 LLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLF 259 >mlr3921 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Length = 346 Score = 161 bits (408), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 16/230 (6%), Positives = 37/230 (16%), Gaps = 10/230 (4%) Query: 55 DLVTEVDKGVEQMIRRLILTHYPDHAILGEESVQPGADALTAALEEGRKHEYLWIVDPID 114 V +M + + E L I + Sbjct: 40 VAQGINLIDVAEMYPVPPRPETQGLTETYVGN---WL-------AKHGSREKLIIASKVS 89 Query: 115 GTTNFVHGFPFYCVSIALVVKGELTVGVIYDPIRDEMFVAEKGKGAYMHGIPTSVSAEAD 174 G + ++ E + D + + + + Sbjct: 90 GPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWT 149 Query: 175 PGSSLVAMGFPPDRTFAQPANMAGLQQILPQIRGIRAGGSAALHLAYVAAGRVDGYWEVG 234 + V++ D + L + V Sbjct: 150 DSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYS 209 Query: 235 LSPWDCAAGVLLVLESGGKVTDTLGNPYDIGTRHVVASNGRIHDFLLASL 284 L G+ V + G + + Sbjct: 210 LLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLF 259 >CC3269 [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Length = 346 Score = 157 bits (398), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 22/247 (8%), Positives = 50/247 (20%), Gaps = 14/247 (5%) Query: 42 GRVKELG-SKTSAQDLVTEVDKGVEQMIRRLILTHYPDHAILGEESVQPGADALTAALEE 100 G + S D ++D V Q I + + E L E Sbjct: 17 GLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQ----------GLTE 66 Query: 101 GRKHEYLWIVDPIDGTTNFVHGFPFYCVSIALVVKGE-LTVGVIYDPIRDEMFVAEKGKG 159 +L + + + + L I + + D + + Sbjct: 67 TYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYL 126 Query: 160 AYMHGIPT-SVSAEADPGSSLVAMGFPPDRTFAQPANMAGLQQILPQIRGIRAGGSAALH 218 + P +A Q+ + +A Sbjct: 127 DLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGV 186 Query: 219 LAYVAAGRVDGYWEVGLSPWDCAAGVLLVLESGGKVTDTLGNPYD-IGTRHVVASNGRIH 277 + Y+ + + +V+ G G+ Sbjct: 187 MRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYL 246 Query: 278 DFLLASL 284 + + Sbjct: 247 NGAKPAG 253 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.136 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,271,490 Number of extensions: 976835 Number of successful extensions: 1798 Number of sequences better than 1.0e-05: 62 Number of HSP's gapped: 1695 Number of HSP's successfully gapped: 62 Length of query: 294 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 188 Effective length of database: 26,153,027 Effective search space: 4916769076 Effective search space used: 4916769076 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 115 (48.9 bits)