BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0443.0016.p
         (247 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH2137 [K] COG1414 Transcriptional regulator                          121   1e-27
Rv2989 [K] COG1414 Transcriptional regulator                          100   2e-21
MT3067 [K] COG1414 Transcriptional regulator                          100   3e-21
BH3725 [K] COG1414 Transcriptional regulator                           91   2e-18
BH1819 [K] COG1414 Transcriptional regulator                           88   1e-17

>BH2137 [K] COG1414 Transcriptional regulator
          Length = 251

 Score =  121 bits (304), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 79/229 (34%), Positives = 121/229 (52%), Gaps = 6/229 (2%)

Query: 8   VRAVERALDIL-LCFTQENDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEATEKYR 66
           V++V+RAL I+ L    +  L +T++A+K+SL KS+ ++LL TL E GF+ ++E T+KYR
Sbjct: 2   VKSVDRALTIISLVSEHKQGLGVTDVAAKLSLTKSSAYKLLATLVEHGFIEQDEETKKYR 61

Query: 67  LGIRIWELSTHLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQSRQAIR 126
           LG R  ELS  L    +      P +E+L     E   L L D  E V I  ++  + +R
Sbjct: 62  LGYRYLELSATLLESIDIRRQARPFLEQLEATTNEVVHLVLYDQGEMVYIDKLEGTKTLR 121

Query: 127 RVAQIGARLPLSVGASSKVLAAYAPQEVQTRLLADPNWP-----EAVDKGAYLGQLQEII 181
             ++IG R P+   +  KV+ AY P++VQ  L+     P        DK  ++ +L++I 
Sbjct: 122 THSKIGRRAPIHCTSVGKVIMAYLPEKVQISLIERYGLPPHTERTITDKETFMKELEKIR 181

Query: 182 RRGYATSFEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLED 230
             GY    EE EP               + AA+S+SGP  RLS+E L +
Sbjct: 182 LEGYGYEMEENEPGITCIAAPIFDYQGAITAAVSISGPSIRLSKERLHE 230


>Rv2989 [K] COG1414 Transcriptional regulator
          Length = 233

 Score =  100 bits (249), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 70/206 (33%), Positives = 104/206 (50%), Gaps = 19/206 (9%)

Query: 24  ENDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEATEKYRLGIRIWELSTHLPTLDE 83
           E+   L E+  +  L ++T +RL   LE    L R +    +RLG  I EL+TH+   D+
Sbjct: 22  ESPCGLAELCDRTDLPRATAYRLAAALEVHRLLGRGQ-DGHWRLGPAITELATHV---DD 77

Query: 84  P----AALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQSRQAIRRVAQIGARLPLSV 139
           P     A +LP   +LRD  GE+  +Y R+   RV + A++    +R    +GARLP++ 
Sbjct: 78  PLLVACAAVLP---QLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVPVGARLPMTA 134

Query: 140 GASSKVLAAYAPQEVQTRLLADPNWPEAVDKGAYLGQLQEIIRRGYATSFEEREPXXXXX 199
           G+ +KVL A+     Q  +L     P+AV        L E+ RRG+A S  EREP     
Sbjct: 135 GSGAKVLLAHTDAATQAAVL-----PKAVFSAR---ALAEVCRRGWAQSVAEREPGVASV 186

Query: 200 XXXXXXXXXTVAAALSLSGPVSRLSR 225
                     V AA+S+SGP+ R+ R
Sbjct: 187 SAPVRDGRGVVIAAISVSGPIDRMGR 212


>MT3067 [K] COG1414 Transcriptional regulator
          Length = 267

 Score = 99.8 bits (247), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 70/206 (33%), Positives = 104/206 (50%), Gaps = 19/206 (9%)

Query: 24  ENDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEATEKYRLGIRIWELSTHLPTLDE 83
           E+   L E+  +  L ++T +RL   LE    L R +    +RLG  I EL+TH+   D+
Sbjct: 56  ESPCGLAELCDRTDLPRATAYRLAAALEVHRLLGRGQ-DGHWRLGPAITELATHV---DD 111

Query: 84  P----AALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQSRQAIRRVAQIGARLPLSV 139
           P     A +LP   +LRD  GE+  +Y R+   RV + A++    +R    +GARLP++ 
Sbjct: 112 PLLVACAAVLP---QLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVPVGARLPMTA 168

Query: 140 GASSKVLAAYAPQEVQTRLLADPNWPEAVDKGAYLGQLQEIIRRGYATSFEEREPXXXXX 199
           G+ +KVL A+     Q  +L     P+AV        L E+ RRG+A S  EREP     
Sbjct: 169 GSGAKVLLAHTDAATQAAVL-----PKAVFSAR---ALAEVCRRGWAQSVAEREPGVASV 220

Query: 200 XXXXXXXXXTVAAALSLSGPVSRLSR 225
                     V AA+S+SGP+ R+ R
Sbjct: 221 SAPVRDGRGVVIAAISVSGPIDRMGR 246


>BH3725 [K] COG1414 Transcriptional regulator
          Length = 251

 Score = 90.9 bits (224), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 71/247 (28%), Positives = 122/247 (49%), Gaps = 7/247 (2%)

Query: 8   VRAVERALDILLCFTQE-NDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEATEKYR 66
           V++V+RAL IL    Q    L +TE+A ++++ KST HRL++TLE   ++ ++  T +Y 
Sbjct: 2   VQSVDRALMILDILKQHPKGLGITELAHELNVAKSTAHRLVSTLETYDYVTQDRETSRYS 61

Query: 67  LGIRIWELSTHLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQSR-QAI 125
           LG++  E+   +    +  A+  P +E L +  GE + L +RD  + V I  V+S    I
Sbjct: 62  LGLKFLEMQQVVMENMDIVAVAHPILEALTEECGEISHLVMRDHFDVVYIDKVESAVSTI 121

Query: 126 RRVAQIGARLPLSVGASSKVLAAYAP----QEVQTRLLADPNWPEAVDKG-AYLGQLQEI 180
           R  ++ G R P+   A  K +AA+      QE   +    P     + +  A+   LQ++
Sbjct: 122 RIYSRTGKRAPIYCTAVGKAIAAHFDEPLLQEYVEQAAFQPLTRHTISEPEAFKAALQKV 181

Query: 181 IRRGYATSFEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLEDYAVVLAENAA 240
           +  GYA   EE E                V  A+S++GP++R++   L+     L + AA
Sbjct: 182 LTDGYAEDNEEHEEGIRCIGAPIFNHLGQVPYAISITGPLARMTDARLQTLIPRLKQAAA 241

Query: 241 EMGLMMG 247
            +   +G
Sbjct: 242 AISRNIG 248


>BH1819 [K] COG1414 Transcriptional regulator
          Length = 252

 Score = 87.8 bits (216), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 66/247 (26%), Positives = 114/247 (46%), Gaps = 12/247 (4%)

Query: 9   RAVERALDILLCFTQENDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEATEKYRLG 68
           + V +++++L  F     L+L E+  +  + K++VHR++ +LEE GFL +      Y LG
Sbjct: 6   KTVIKSMNLLNLFRTYPTLTLQEMVKQSGMPKTSVHRMINSLEEMGFLQKRHDG-AYELG 64

Query: 69  IRIWELSTHLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQSRQAIRRV 128
           +   EL   +    +   +  P ME LR+++ E   L +RD  E + I+ + +   +R  
Sbjct: 65  VVFLELGQLVSDRLDLRQVAFPIMEALRNQVEEAVHLTVRDGDEAIYIEKLDTLHPVRLF 124

Query: 129 AQIGARLPLSVGASSKVLAAYAPQEVQTRL--------LADPNWPEAVDKGAYLGQLQEI 180
            ++G R PL  GA  +V+ ++ P++ QT          LAD       DK     ++ E 
Sbjct: 125 TKVGRRAPLYAGACQRVILSFLPEQEQTAYLERVELIPLADGT---ITDKLLLKERISET 181

Query: 181 IRRGYATSFEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLEDYAVVLAENAA 240
            + G A S  E E               T+ A +S++GP  R++ E L    V L   A 
Sbjct: 182 QQTGVAISHSELENNTTAIAAPIYDHSGTIVAGISIAGPDIRVTEERLSTLKVTLKNAAK 241

Query: 241 EMGLMMG 247
            +   +G
Sbjct: 242 SISKQLG 248


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.318    0.132    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 14,912,088
Number of extensions: 526693
Number of successful extensions: 1668
Number of sequences better than 1.0e-05: 66
Number of HSP's gapped: 1627
Number of HSP's successfully gapped: 66
Length of query: 247
Length of database: 38,378,431
Length adjustment: 104
Effective length of query: 143
Effective length of database: 26,383,695
Effective search space: 3772868385
Effective search space used: 3772868385
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 114 (48.5 bits)