BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0442.0008.p (501 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SSO0632 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidot... 298 1e-80 PAE0226 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidot... 221 2e-57 SSO0633 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidot... 218 2e-56 PAE0218 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidot... 109 1e-23 mlr6774 [M] COG0449 Glucosamine 6-phosphate synthetase, contains... 96 1e-19 >SSO0632 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase Length = 252 Score = 298 bits (764), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 0/468 (0%), Positives = 0/468 (0%), Gaps = 29/468 (6%) Query: 32 FDTLKEECGVFGVFGHPEA-ASMSYYGLHALQHRGEESAGICVADGRDFHYHRGMGLVKE 90 + + + + Sbjct: 1 MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITG 60 Query: 91 VFDKDKIASLVGNMSIGHVRYSTSGDSRLTNAQPLVFKYRDGDLAIATNGNIVNEPLIRK 150 + S D R D A A+ + + Sbjct: 61 ID-SSPAMIAEAR-SALPDCQFVEADIRNWQPVQA----LDLIFANASLQWLPD------ 108 Query: 151 QLEQSGSIFQTTSDTEVLAHLIARSQ--KEFVEATKDALQQLVGGFAFLLMTNDK-LIVA 207 + ++A + + A Sbjct: 109 -HYELFPH---LVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHA 164 Query: 208 SDTHGLRPLVMGRVGEAYVFASESCALEVIGAQFVRDIEPGELLVLDQNGFREDRFAXXX 267 + + +I + P + + + Sbjct: 165 YYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQM 224 Query: 268 XPQRKALCAMEYIYFARPDSDLNGSNLHAARKRMGSRMALEAFVDADIVTGVPDSSISAA 327 Sbjct: 225 -- 282 Query: 328 IGYAEQTGIPYELGLIKNKYTGRTFIQPSQELREQGVKMKLSAVRRVVEGQRVVMIDDSI 387 Sbjct: 283 342 Query: 388 VRGTTSRRIVNLLREAGATEVHVRITSPPFKNPCFYGIDTPDRRELIASYKTVEEICHEI 447 Sbjct: 343 402 Query: 448 NADSLAFLTPAGLIQAIGGYNSGDYKGGLCLSCFDNDYPTQVDFGGEE 495 Sbjct: 403 ------- 443 >PAE0226 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase Length = 252 Score = 221 bits (563), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 0/455 (0%), Positives = 0/455 (0%), Gaps = 50/455 (10%) Query: 39 CGVFGVFGHPEAASMSYYGLHALQHRGEESAGICVADGRDFHYHRGMGLVKEVFDKDKIA 98 ++ L R + + Sbjct: 2 SDWNPSLYL-HFSAERSRPAVELLARVPLENV--------EYVADLGCGPGNSTALLQQR 52 Query: 99 SLVGNMSIGHVRYSTSGDSRLTNAQPLVFKYRDGDLAIATNGNIVNEPLIRKQLEQSGSI 158 + A+ + + + Sbjct: 53 WPA------ARITGIDSSPAM-IAEARSALPDCQFVEADIRNWQPVQ----ALDLIFANA 101 Query: 159 FQTTSDTEVLAHLIARS--QKEFVEATKDALQQLVGGFAFLLMTNDKLIVASDTHGLRPL 216 + H A+Q + ++ + Sbjct: 102 S----LQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGRE 157 Query: 217 VMGRVGEAYVFASESCALEVIGAQFVRDIEPGELLVLDQNGFREDRFAXXXXPQRKA-LC 275 + V Y SE+ + Q Sbjct: 158 PLAGVHAYYDILSEAGCEV--DIW---RTTYYHQMPSHQ------AIIDWVTATGLRPWL 206 Query: 276 AMEYIYFARPDSDLNGSNLHAARKRMGSRMALEAFVDADIVTGVPDSSISAAIGYAEQTG 335 Sbjct: 207 266 Query: 336 IPYELGLIKNKYTGRTFIQPSQELREQGVKMKLSAVRRVVEGQRVVMIDDSIVRGTTSRR 395 Sbjct: 267 --- 323 Query: 396 IVNLLREAGATEVHVRITSPPFKNPCFYGIDTPDRRELIASYKTVEEICHEINADSLAFL 455 Sbjct: 324 383 Query: 456 TPAGLIQAIGGYNSGDYKGGLCLSCFDNDYPTQVD 490 Sbjct: 384 --------- 409 >SSO0633 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase Length = 252 Score = 218 bits (554), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 0/453 (0%), Positives = 0/453 (0%), Gaps = 59/453 (13%) Query: 39 CGVFGVFGHPEAASMS---YYGLHALQHRGEESAGICVADGRDFHYHRGMGLVKEVFDKD 95 + E + + + G + R D Sbjct: 5 NPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITGID-- 62 Query: 96 KIASLVGNMSIGHVRYSTSGDSRLTNAQPLVFKYRDGDLAIATNGNIVNEPLIRKQLEQS 155 + + + + N V + Sbjct: 63 -SSPAMIAEARSA--------LPDCQFVEADIR----------NWQPVQALDL------- 96 Query: 156 GSIFQTTSDTEVLAHLIARSQKEFVEATKDALQQLVGGFAFLLMTND-KLIVASDTHGLR 214 + + LV + + + Sbjct: 97 -------IFANASLQWLPDHY--------ELFPHLVSLLNPQGVLAVQMPDNWLEPTHVL 141 Query: 215 PLVMGRVG-EAYVFASESCALEVIGAQFVRDIEPGELLVLDQNGFREDRFAXXXXPQRKA 273 + + ++ A Sbjct: 142 MREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAI----IDWV 197 Query: 274 LCAMEYIYFARPDSDLNGSNLHAARKRMGSRMALEAFVDADIVTGVPDSSISAAIGYAEQ 333 Sbjct: 198 257 Query: 334 TGIPYELGLIKNKYTGRTFIQPSQELREQGVKMKLSAVRRVVEGQRVVMIDDSIVRGTTS 393 Sbjct: 258 317 Query: 394 RRIVNLLREAGATEVHVRITSPPFKNPCFYGIDTPDRRELIASYKTVEEICHEINADSLA 453 Sbjct: 318 377 Query: 454 FLTPAGLIQAIGGYNSGDYKGGLCLSCFDNDYP 486 Sbjct: 378 ------- 403 >PAE0218 [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase Length = 252 Score = 109 bits (272), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 0/231 (0%), Positives = 0/231 (0%), Gaps = 8/231 (3%) Query: 226 VFASESCALEVIGAQFVRDIEPGELLVLDQNGFREDRFAXXXXPQRKALCAMEYIYFARP 285 + + + E L + Y P Sbjct: 134 WLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYD----ILSEAGCEV-DIWRTTYYHQMP 188 Query: 286 DSDLNGSNLHAARKRMGSRMALEAFVDADIVTGVPDSSISAAIGYAEQTGIPYELGLIKN 345 + A R + E+ + + L Sbjct: 189 SHQAIIDWVTATGLRPWLQDLTESE-QQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIV 247 Query: 346 KYTGRTFIQPSQELREQGVKMKLSAVRRVVEGQRVVMIDDSIVRGTTSRRIVNLLR-EAG 404 Sbjct: 248 - 306 Query: 405 ATEVHVRITSPPFKNPCFYGIDTPDRRELIASYKTVEEICHEINADSLAFL 455 Sbjct: 307 357 >mlr6774 [M] COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Length = 346 Score = 95.9 bits (237), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 10/200 (5%), Positives = 33/200 (16%), Gaps = 9/200 (4%) Query: 39 CGVFGVFGHPEAASMSYYGLHALQHRGEESAGICVADGRDFHYHRGMGLVKEVFDKDKIA 98 E +++ + + E A + + Sbjct: 2 QYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPET 61 Query: 99 SLVGNMSIGHVRYSTSGDSRLTNAQPLVFKYRDGDLAIATNGNIVNEPLIRKQLEQSGSI 158 + +G+ +L A + E Sbjct: 62 QGLTETYVGNWLAKHGSREKLIIASK---VSGPS-RNNDKGIRPDQALDRKNIREALHDS 117 Query: 159 FQTTSDTEVLAHLIARSQK---EFVEATKDALQQLVGGFAFLLM-TNDKLIVASDTHGLR 214 + + + + Q+ F + + + A Sbjct: 118 LKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRY-I 176 Query: 215 PLVMGRVGEAYVFASESCAL 234 + + + Sbjct: 177 GVSNETAFGVMRYLHLADKH 196 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,632,160 Number of extensions: 1560467 Number of successful extensions: 3206 Number of sequences better than 1.0e-05: 37 Number of HSP's gapped: 3172 Number of HSP's successfully gapped: 37 Length of query: 501 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 390 Effective length of database: 25,576,357 Effective search space: 9974779230 Effective search space used: 9974779230 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)