BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0440.0012.p (391 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0764 [K] COG1609 Transcriptional regulators 175 9e-44 SPy1602 [K] COG1609 Transcriptional regulators 118 2e-26 L0146 [K] COG1609 Transcriptional regulators 114 4e-25 BH1875 [K] COG1609 Transcriptional regulators 90 6e-18 BS_araR [K] COG1609 Transcriptional regulators 82 1e-15 >lin0764 [K] COG1609 Transcriptional regulators Length = 372 Score = 175 bits (444), Expect = 9e-44, Method: Compositional matrix adjust. Identities = 123/351 (35%), Positives = 183/351 (52%), Gaps = 17/351 (4%) Query: 10 KKPLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRV 69 K LYQ +Y +K IQ GK G ++PTE EL +DVS +T K A+ LL ++G+I R Sbjct: 2 KTLLYQKVYDQLKLSIQEGKIPVGSKMPTENELMAQFDVSSITLKKALELLKKDGYISRR 61 Query: 70 SGKGSFVSELAVEQANRSEQRQAR-----LIGLILAGFSDSYGTELLRTMIHELTRRGYH 124 G+FV + + SEQ + R L G I+ F D++GT LL M+ E + H Sbjct: 62 PRVGTFV----INDSPNSEQIETRKFDKPLFGCIMTNFDDTFGTILLSGML-EHSDSKAH 116 Query: 125 AILKISNESQEMETQYLNELIALGVQGILILPVQAEFHNVALLKVTLSNFPIVLVDRRLS 184 I+K S E E + L E I + V GILILP ++F + LL++ FP+V++DR L Sbjct: 117 IIVKKSLGDTEREEEILQEFIEMNVAGILILPASSKFVSPTLLELASQKFPLVVIDRTLE 176 Query: 185 GVSVPYVGSNNKEIAHQLTMKLLNSGHNKISVISHENLNNSSLNDRMDGIRDAYMEKQVX 244 G+ + + S+N E +T KL GH I +I+ + S+L+ R++G + Sbjct: 177 GLPISSISSDNTEAGRIITEKLFELGHKHIGMITSTS-PVSTLDSRVNGFIRGHASFHTA 235 Query: 245 XXXXXXXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFALDYLSGQILWYALHQ 304 E+ N T ++ D KI + L+ PEIT A +Y ++ A ++ Sbjct: 236 FHSDYVFREIESVMPN--STVSIQTDIDKIARFLETHPEITALVATEYNIALLIKQACNK 293 Query: 305 IGKSIPEDYSLLSFDGPLQNFLSPS---FTRIIQNQPEIGLHAVGLLLQMI 352 +GKSIP + S++ FD P NF S FT I Q Q EIG+ AV +LL + Sbjct: 294 LGKSIPTNLSVVCFDHP-DNFFDTSAFQFTHIKQAQYEIGVKAVDMLLNQV 343 >SPy1602 [K] COG1609 Transcriptional regulators Length = 346 Score = 118 bits (296), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 103/352 (29%), Positives = 173/352 (49%), Gaps = 31/352 (8%) Query: 11 KPLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRVS 70 K LY+ IY IKE I SG+ GD++PTEKEL++ + VSR+T+K A+ L +EG I R Sbjct: 3 KLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRITSKRALVELEQEGLITRSR 62 Query: 71 GKGSFVSELAVEQANRSEQRQARLIGLILAGFSDSYGTELLRTMIHELTRRGYHAILKIS 130 GKGSFV++ +Q E + L LIL SD + + ++ + GY +++++ Sbjct: 63 GKGSFVAK---KQVTSPEANKDLL--LILPFASDYELGDYAKGIMTSIAETGYRLMVQLA 117 Query: 131 NESQEMETQYLNELIALGVQGILILPVQAEFHNVALLKVTLSNFPIVLVDRRLSGVSVPY 190 + T L+ L GI+ P L + P+VL+D+ L P Sbjct: 118 S------TVRLDTLSDYA--GIIYYPEDVNHSIDFLFYCDHHHIPLVLLDKSLDLFQFPS 169 Query: 191 VGSNNKEIAHQLTMKLLNSGHNKISVISHENLNN-SSLNDRMDGIRDAYMEKQVXXXXXX 249 V ++NK A QLT L+ G ++IS ++ + SS+ DR G A E + Sbjct: 170 VVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAMAESSL------ 223 Query: 250 XXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFAL--DYLSGQILWYALHQIGK 307 ++ Y+ ++T+ + ++ + L E + D+L+ Q++ + Q+G Sbjct: 224 -----KSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQ-KITQVGL 277 Query: 308 SIPEDYSLLSFDGP-LQNFLSPSFTRIIQNQPEIGLHAVGLLLQMIESGQPD 358 SIP+ +++ FD LSP + Q+ ++G A +LLQ+I +PD Sbjct: 278 SIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIH--EPD 327 >L0146 [K] COG1609 Transcriptional regulators Length = 345 Score = 114 bits (284), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 103/352 (29%), Positives = 165/352 (46%), Gaps = 38/352 (10%) Query: 12 PLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRVSG 71 PLYQ I +K+ I + + GDQ+PTEKEL++ Y VSR+TAK A+ L + G + R G Sbjct: 4 PLYQQISDDLKQKIVTKTFKSGDQLPTEKELSETYSVSRITAKRALTELEQLGLVSRTRG 63 Query: 72 KGSFVSELAVEQANRSEQRQARLIGLILAGFSDSYGTELLRTMIHELTRRGYHAILKISN 131 KG+FV EL N++ + + + I+ S+G + T +G LK+ N Sbjct: 64 KGTFVQEL-----NKNHTKLLKRVLFIIPFEGMSFG---------DFT-QGLVPALKVEN 108 Query: 132 ESQEMETQ-YLNELIALGVQ----GILILPVQAEFHNVALLKVTLSNFPIVLVDRRLSGV 186 + + + YL E A ++ G++ P+ E + LL+++L NFP+VL+D+++ + Sbjct: 109 TTVFITYESYLKENTADDIKENFDGLIYYPMYTEDYLDILLELSLQNFPVVLLDKQIYDL 168 Query: 187 SVPYVGSNNKEIAHQLTMKLLNSGHNKIS-VISHENLNNSSLNDRMDGIRDAYMEKQVXX 245 P V S+N Q LLN GH +I+ V S++ + + +R G E+ + Sbjct: 169 GFPCVSSDNFNGGEQAAQALLNLGHKRIAFVASNDTHHPQTTRNRYLGYVKVLKEQGIKF 228 Query: 246 XXXXXXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPEITCFFALDYLSGQILWYALHQI 305 + L D+ E +L ++T + L L Sbjct: 229 ------------HTTLDDSLYTESSV----LELIHNEKVTGLICENDLVALQTMKTLQDS 272 Query: 306 GKSIPEDYSLLSFDGPLQNFLS-PSFTRIIQNQPEIGLHAVGLLLQMIESGQ 356 S+P D S++ FD LS P T I Q+ +G A LLL I+SGQ Sbjct: 273 HFSVPNDISIIGFDDIQAASLSNPPLTTIAQDFIGMGRIAGELLLDWIKSGQ 324 >BH1875 [K] COG1609 Transcriptional regulators Length = 375 Score = 90.1 bits (222), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 83/354 (23%), Positives = 164/354 (46%), Gaps = 24/354 (6%) Query: 14 YQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRVSGKG 73 Y + Q IK I G P ++ +E EL Y+VSR T + A++ L EGW++R G G Sbjct: 5 YNFVKQQIKSKILEGIVLPHGKIGSENELMKEYNVSRHTVRKAIDELVNEGWVYRKQGAG 64 Query: 74 SFVSELAVEQANRSEQRQARLIGLILAGFSDSYGTELLRTMIHELTRRGYHAILKISNES 133 +F ++ +Q N + Q + I LI S+ ++R L+ GY + +N + Sbjct: 65 TFCAD-RTDQKNPIGKAQRKNIALITTYLSEYIFPSIIRGAESILSEHGYQVTIFSTNNN 123 Query: 134 QEMETQYLNELIALGVQGILILPVQAEFHNVAL---LKVTLSNFPIVLVDRRLSGVSVPY 190 E E + L +++ G+++ P ++ N + L + P V+++ + + Sbjct: 124 HEQEKRALEAVLSQRFDGLIVEPTKSSIPNPNINYYLNLERQGIPYVMINAYYEELEPYF 183 Query: 191 VGSNNKEIAHQLTMKLLNSGHNKI-SVISHENLNNSSLNDRMDGIRDAYMEKQVXXXXXX 249 +G ++ + + T LL+ GH +I + +++L + R+ G A+ E+ + Sbjct: 184 LGMDDVKGGYTQTKHLLDLGHEQIVGLFKNDDLQGAK---RLKGFIKAHRERGIALNPQH 240 Query: 250 XXXXXETSYWNLSDTQLLERDFQKIYQKLQEKPE-ITCFFALDYLSGQILWYALHQIGKS 308 T + + LE + +I++ +P I C+ D L+ ++L + + Sbjct: 241 II----TYTTEQKNAKPLE-ELHRIFKDRSHRPTGIVCYN--DELALKLLD-VIREFDIR 292 Query: 309 IPEDYSLLSFDGPLQNFLSPS----FTRIIQNQPEIGLHAVGLLLQMIESGQPD 358 +PE+ S++ +D +FLS + T I + E+G+ A L++ IE + D Sbjct: 293 VPEELSVVGYD---DSFLSVASEVKLTTIQHPKVEMGIDAAKLIISCIEQERKD 343 >BS_araR [K] COG1609 Transcriptional regulators Length = 384 Score = 82.4 bits (202), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 77/369 (20%), Positives = 164/369 (44%), Gaps = 18/369 (4%) Query: 12 PLYQTIYQSIKEGIQSGKYAPGDQVPTEKELTDMYDVSRLTAKNAMNLLAEEGWIHRVSG 71 P Y + + I I GK P ++PTE EL + VSR T + A+ L +G ++ V G Sbjct: 25 PKYAQVKEEISSWINQGKILPDQKIPTENELMQQFGVSRHTIRKAIGDLVSQGLLYSVQG 84 Query: 72 KGSFVSELAVEQANRSEQRQARLIGLILAGFSDSYGTELLRTMIHELTRRGYHAILKISN 131 G+FV+ + + A S + IG++ SD ++R + L+ +GY +L +N Sbjct: 85 GGTFVASRSAKSALHSN----KTIGVLTTYISDYIFPSIIRGIESYLSEQGYSMLLTSTN 140 Query: 132 ESQEMETQYLNELIALGVQGILILPVQAEFHNVAL---LKVTLSNFPIVLVDRRLSGVSV 188 + + E + L L++ + G+++ P ++ + L + + P +++ + ++ Sbjct: 141 NNPDNERRGLENLLSQHIDGLIVEPTKSALQTPNIGYYLNLEKNGIPFAMINASYAELAA 200 Query: 189 PYVGSNNKEIAHQLTMKLLNSGHNKISVISHENLNNSSLNDRMDGIRDAYMEKQVXXXXX 248 P ++ + LL+ GH + I +++ RM+G A+ E+++ Sbjct: 201 PSFTLDDVKGGMMAAEHLLSLGHTHMMGIF--KADDTQGVKRMNGFIQAHRERELFPSPD 258 Query: 249 XXXXXXETSYWNLSDTQLLERDFQKIYQKLQEKP-EITCFFALDYLSGQILWYALHQIGK 307 T +++LLE+ + + + P I C+ D ++ +++ L ++ Sbjct: 259 MIV----TFTTEEKESKLLEKVKATLEKNSKHMPTAILCYN--DEIALKVID-MLREMDL 311 Query: 308 SIPEDYSLLSFDGP-LQNFLSPSFTRIIQNQPEIGLHAVGLLLQMIESGQPDYKEVIVKT 366 +PED S++ +D T + + +G A ++ +E +P ++VI + Sbjct: 312 KVPEDMSIVGYDDSHFAQISEVKLTSVKHPKSVLGKAAAKYVIDCLEHKKPKQEDVIFEP 371 Query: 367 RFLDNDSIR 375 + S R Sbjct: 372 ELIIRQSAR 380 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.134 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 27,591,922 Number of extensions: 1173422 Number of successful extensions: 12235 Number of sequences better than 1.0e-05: 139 Number of HSP's gapped: 12238 Number of HSP's successfully gapped: 139 Length of query: 391 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 283 Effective length of database: 25,922,359 Effective search space: 7336027597 Effective search space used: 7336027597 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 117 (49.7 bits)