BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0438.0006.p (497 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3372 [R] COG0613 Predicted metal-dependent phosphoesterases (P... 197 4e-50 BH2283 [R] COG0613 Predicted metal-dependent phosphoesterases (P... 184 2e-46 BH1498 [J] COG1670 Acetyltransferases, including N-acetylases of... 120 6e-27 SP1237 [J] COG1670 Acetyltransferases, including N-acetylases of... 113 6e-25 DR0798 [J] COG1670 Acetyltransferases, including N-acetylases of... 103 5e-22 >BH3372 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) Length = 266 Score = 197 bits (500), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 107/252 (42%), Positives = 153/252 (60%), Gaps = 12/252 (4%) Query: 216 AGRADLHTHTLASDGMQSPAENVRLAHEKGLAAVAITDHDTVAGVAEALEAGRKYGITVV 275 AG DLH HT ASDG SP V+ A E GL +AITDHDT+ G+ EA+ AG+++GI V+ Sbjct: 9 AGAFDLHIHTTASDGEYSPTAIVKKAKEIGLRTIAITDHDTLDGIEEAVIAGKRHGINVI 68 Query: 276 PGVEISTRAGGKEIHVLGYYMDTQQEL--FLSRLAEQRDTRAQRNEAIIAKLQALGIAIT 333 P +E++T+ G + +LGY + ++L L +L + R+ RA + II K +G IT Sbjct: 69 PAIELTTKYKGTNVDILGYNVKASEKLQAILVQLKKHREGRAMQ---IIEKFNDIGFTIT 125 Query: 334 MDQVTAGIGRELKPDESVGRPHIADELVRLGAAVDMRDAFDKYLAEGAAAFVSPPRITPE 393 +D+V ++ D + RPHIA +V+ G +D + FD+YLA+G + +TPE Sbjct: 126 LDEV-----KQFSEDGVIARPHIAKAIVKKGYVLDYQTVFDEYLADGKPCAIDKMILTPE 180 Query: 394 LACEWIAEAGGAAVLAHPGIYGDDELVRSIIERSALRGIEAYHSDHSPADAERYLALAEE 453 + I EAGG A+LAHP +Y +D LVR ++ GIE +H +H D E+Y LA E Sbjct: 181 EGIKLIHEAGGKAILAHP-VYLEDTLVRELLALD-FDGIEVWHRNHDETDQEKYKMLATE 238 Query: 454 FGLLVTGGSDFH 465 F L+ TGGSDFH Sbjct: 239 FALIKTGGSDFH 250 >BH2283 [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) Length = 290 Score = 184 bits (468), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 106/275 (38%), Positives = 149/275 (54%), Gaps = 20/275 (7%) Query: 219 ADLHTHTLASDGMQSPAENVRLAHEKGLAAVAITDHDTVAGVAEALEAGRKYGITVVPGV 278 +DLH H+ ASDG SP E + H+ L VA+TDHDTV G+ EA + + G ++PG+ Sbjct: 7 SDLHMHSTASDGGYSPTELMEKCHQANLKFVALTDHDTVNGIEEAKQTAHRLGFILIPGI 66 Query: 279 EISTRAGGKEIHVLGYYMDTQQELFLSRLAEQRDTRAQRNEAIIAKLQALGIAITMDQVT 338 E+ST+A G+ +H+LGY +D + + RL Q+D R QR E I+ KL+A G+ + D V Sbjct: 67 ELSTKASGQSVHMLGYGIDWKNDTLKRRLDRQQDIRKQRLEQILLKLKAAGVPLEQDAVL 126 Query: 339 AGIGRELKPDESVGRPHIADELVRLGAAVDMRDAFDKYLAEGAAAFVSPPR-ITPELACE 397 ++GRPH+A L+ G +++AF+ YLAEG +V I+ E A Sbjct: 127 -----RYADGGAIGRPHVAKALMDKGYVRSVQEAFEHYLAEGRPCYVKRQEYISVEQAIA 181 Query: 398 WIAEAGGAAVLAHPGIYGDDELVRSIIERSALRGIEAYHSDHSPADAERYLALAEEF--- 454 WI +AGG A++AHPG Y D+ + + L GIE YH DHS Y L + Sbjct: 182 WIHQAGGVAIVAHPGYYDLDDQLIGWVREYGLDGIEVYHRDHSREVVAHYEQLCKRMEAE 241 Query: 455 ---GLLVTGGSDFHGARQGVVFHGEIGSVSVPVGV 486 LL TGGSDFH H G + P+G Sbjct: 242 TGRRLLRTGGSDFH--------HESYGRTAAPLGT 268 >BH1498 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins Length = 176 Score = 120 bits (300), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 78/180 (43%), Positives = 108/180 (60%), Gaps = 8/180 (4%) Query: 8 EKVTLRDL-TEEDIRTLYYYEFEAEDREHLLWNGPYGTQEWESYETFAPKFAEILALTYT 66 +V LR E D + L+ + A D++ +NGPY E E+YETF + A Sbjct: 2 NRVRLRTAEAEADYKRLFELMYVAADQQWREYNGPYFPFEEETYETFYESKKKAFA---- 57 Query: 67 GEPRSRLVVEIDGQLKGTVGRYWVSKVTNWFEIGIVLFDSRDWSGGYGTEAFRMWMGYLF 126 E R +L+ ++ G + GTV YW + T W E GIV++DS W+GGYGTEAF+ W+ LF Sbjct: 58 -EGRLKLI-DVKGAIIGTVNYYWEYQPTRWLESGIVIYDSTFWNGGYGTEAFKQWITELF 115 Query: 127 -DSLDTVRLGIGTWSGNVRMMGLAAKCGMIEEARVRKARIVRGEYYDAIKMGILREEWEA 185 + + R+G TWSGN MM + K GM+ EAR+RK R RG YYD I+ G+LREEW++ Sbjct: 116 ANDPEIARVGFTTWSGNPGMMKIGEKLGMMLEARLRKVRYHRGTYYDQIRYGVLREEWKS 175 >SP1237 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins Length = 187 Score = 113 bits (283), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 67/177 (37%), Positives = 101/177 (57%), Gaps = 6/177 (3%) Query: 10 VTLRDLTEEDIRTLYYYEFEAEDREHLLWNGPYGTQEWESYETFAP-KFAEILALTYTGE 68 + LR L +ED+ +L+ + + ++ PY ++ Y+ F+ K E+ Sbjct: 2 IYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPY----YDDYQYFSNFKEFELQKSESILS 57 Query: 69 PRSRLVVEIDGQLKGTVGRYWVSKVTNWFEIGIVLFDSRDWSGGYGTEAFRMWMGYLF-D 127 +RL + +D +L GTV RYWV K T W E+GI ++D + W+ G G A W+ F D Sbjct: 58 NSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGIGKVAMLQWIDRTFQD 117 Query: 128 SLDTVRLGIGTWSGNVRMMGLAAKCGMIEEARVRKARIVRGEYYDAIKMGILREEWE 184 L+ LG+ TWSGN+ MM LA K M +EA + K R +G+Y+D+IK GILRE+WE Sbjct: 118 YLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKYFDSIKYGILREDWE 174 >DR0798 [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins Length = 207 Score = 103 bits (258), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 59/187 (31%), Positives = 97/187 (51%), Gaps = 10/187 (5%) Query: 2 AVLLKGEKVTLRDLTEEDIRTLYYYEFEAEDREHLLWNGPYGTQEWESYETFAPK---FA 58 A L ++TLR+ ED+ +++E E LW+ PY +E P A Sbjct: 8 ASLTMMPELTLRERRPEDLPIQWHWEHEQPRPAWKLWDAPY------FHEPSQPSTLGLA 61 Query: 59 EILALTYTGEPRSRLVVEIDGQLKGTVGRYW-VSKVTNWFEIGIVLFDSRDWSGGYGTEA 117 E A ++ +D + G + R+ + + W+EIG++++D W GG+G +A Sbjct: 62 EYCAKMNEQGSEGLRIIALDDRCIGEISRFQEKPRDSGWWEIGVLIYDPAHWGGGFGRQA 121 Query: 118 FRMWMGYLFDSLDTVRLGIGTWSGNVRMMGLAAKCGMIEEARVRKARIVRGEYYDAIKMG 177 R+W F D + + TWSGN RM+ A + G E AR+ +AR+ +G+ +D++K+G Sbjct: 122 LRLWTDATFAETDAHLITLTTWSGNERMVRAAQRAGYRECARIPEARLWQGQRWDSVKLG 181 Query: 178 ILREEWE 184 ILR EWE Sbjct: 182 ILRREWE 188 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 39,277,331 Number of extensions: 1833930 Number of successful extensions: 3446 Number of sequences better than 1.0e-05: 16 Number of HSP's gapped: 3438 Number of HSP's successfully gapped: 16 Length of query: 497 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 386 Effective length of database: 25,576,357 Effective search space: 9872473802 Effective search space used: 9872473802 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)