BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0040.p (70 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC3381 [O] COG0330 Membrane protease subunits, stomatin/prohibi... 55 3e-08 >CAC3381 [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs Length = 365 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 23/41 (56%), Positives = 34/41 (82%) Query: 22 VQRQEEDVATFILSRIQEKEEEFGVRFLGAGVKDVILPGEM 62 + Q+E++ FILSR++EKE E+ V F+GAG+KD+ILPGE+ Sbjct: 243 ILNQKEEIGGFILSRLKEKEREYYVEFIGAGIKDIILPGEV 283 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.140 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 4,991,808 Number of extensions: 196615 Number of successful extensions: 301 Number of sequences better than 1.0e-05: 1 Number of HSP's gapped: 301 Number of HSP's successfully gapped: 1 Length of query: 70 Length of database: 38,378,431 Length adjustment: 42 Effective length of query: 28 Effective length of database: 33,534,403 Effective search space: 938963284 Effective search space used: 938963284 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 109 (46.6 bits)