BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0030.p (177 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin1898 [R] COG2249 Putative NADPH-quinone reductase (modulator ... 173 1e-43 BS_ywrO [R] COG2249 Putative NADPH-quinone reductase (modulator ... 159 2e-39 BS_ydeQ [R] COG2249 Putative NADPH-quinone reductase (modulator ... 157 9e-39 BS_yrkL [R] COG2249 Putative NADPH-quinone reductase (modulator ... 155 3e-38 CC0205 [R] COG2249 Putative NADPH-quinone reductase (modulator o... 103 1e-22 >lin1898 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 173 bits (439), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 11/174 (6%), Positives = 34/174 (19%) Query: 1 MKTLIILAHPNLEASRVNQRWKEELRQYPNDITVHELYKEYPDGNIDVPREQNLLEGYHH 60 M+ I ++ + D Y N+ E + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 61 IILQFPLYWYSYPPLLKKWFDEVWTYGWAYXXXXXXXXXXXXXXAISIGDKQENYQPEGS 120 Y ++ + + ++ + Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 121 VSFTVDEVIAPFKASAGHVGAVALPYFAVFGASFQASDEDINHSAKEYINYILK 174 + ++ L Y A + + ++ A+ ++ Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIR 174 >BS_ywrO [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 159 bits (402), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 9/172 (5%), Positives = 28/172 (16%), Gaps = 2/172 (1%) Query: 1 MKTLIILAHPNLEASRVNQRWKEELRQYPNDITVHELYKEYPDGNIDVPREQNLLEGYHH 60 M+ I ++ + +L G + + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEA-DAHAQLDYAVAQGINLIDVAEMYPVPPRP 59 Query: 61 IILQFPLYWYSYPPLLKKWFDEVWTYGWAYXXXXXXXXXXXXXXAISIGDKQENYQPEGS 120 + +++ A+ + +E Sbjct: 60 ETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLK 119 Query: 121 VSFTVDEVIAPFKASAGHVGAVALPYFAVFGASFQASDEDINHSAKEYINYI 172 T + ++ ++ S A Sbjct: 120 RLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVS-LLDTLDALAEYQRA 170 >BS_ydeQ [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 157 bits (397), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 5/172 (2%), Positives = 28/172 (16%), Gaps = 2/172 (1%) Query: 1 MKTLIILAHPNLEASRVNQRWKEELRQYPNDITVHELYKEYPDGNIDVPREQNLLEGYHH 60 + + ++ + + + Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADA-HAQLDYAVAQGINLIDVAEMYPVPPRPETQ 62 Query: 61 IILQFPLYWYSYPPLLKKWFDEVWTYGWAYXXXXXXXXXXXXXXAISIGDKQENYQPEGS 120 + + + + ++ +I + + Sbjct: 63 GLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQ 122 Query: 121 VSFTVDEVIAPFKASAGHVGAVALPYFAVFGASFQASDEDINHSAKEYINYI 172 + + + G + + A D + + I Sbjct: 123 TDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAV-SLLDTLDALAEYQRAGKI 173 >BS_yrkL [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 155 bits (392), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 10/172 (5%), Positives = 27/172 (15%), Gaps = 2/172 (1%) Query: 1 MKTLIILAHPNLEASRVNQRWKEELRQYPNDITVHELYKEYPDGNIDVPREQNLLEGYHH 60 M+ I ++ + +L G + + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQN-SEADAHAQLDYAVAQGINLIDVAEMYPVPPRP 59 Query: 61 IILQFPLYWYSYPPLLKKWFDEVWTYGWAYXXXXXXXXXXXXXXAISIGDKQENYQPEGS 120 + +++ A+ + +E Sbjct: 60 ETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLK 119 Query: 121 VSFTVDEVIAPFKASAGHVGAVALPYFAVFGASFQASDEDINHSAKEYINYI 172 T + ++ S A A Sbjct: 120 RLQTDYLDLYQVHWPQRPTNCFGKLGYSWTD-SAPAVSLLDTLDALAEYQRA 170 >CC0205 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 5/166 (3%), Positives = 23/166 (13%), Gaps = 2/166 (1%) Query: 3 TLIILAHPNLEASRVNQRWKEELRQYPNDITVHELYKEYPDGNIDVPREQNLLEGYHHII 62 + + E + + ++ E Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAH-AQLDYAVAQGINLIDVAEMYPVPPRPETQGLTE 66 Query: 63 LQFPLYWYSYPPLLKKWFDEVWTYGWAYXXXXXXXXXXXXXXAISIGDKQENYQPEGSVS 122 + + K + I + + Sbjct: 67 TYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYL 126 Query: 123 FTVDEVIAPFKASAGHVGAVALPYFAVFGASFQASDEDINHSAKEY 168 + + A + + + + + Sbjct: 127 DLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLD-TLDALAEYQRAG 171 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 13,140,950 Number of extensions: 487106 Number of successful extensions: 1479 Number of sequences better than 1.0e-05: 25 Number of HSP's gapped: 1462 Number of HSP's successfully gapped: 25 Length of query: 177 Length of database: 38,378,431 Length adjustment: 99 Effective length of query: 78 Effective length of database: 26,960,365 Effective search space: 2102908470 Effective search space used: 2102908470 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 112 (47.8 bits)