BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0437.0013.p (150 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value L170990 [KR] COG0454 Histone acetyltransferase HPA2 and related ... 124 5e-29 PA1428 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 103 1e-22 PA0249 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 82 3e-16 STM3643 [KR] COG0454 Histone acetyltransferase HPA2 and related ... 55 5e-08 yiaC [KR] COG0454 Histone acetyltransferase HPA2 and related ace... 54 9e-08 >L170990 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 147 Score = 124 bits (311), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 59/139 (42%), Positives = 93/139 (66%), Gaps = 1/139 (0%) Query: 13 RNEEVSHQLLYIWETAVRATHLFLTEQNIAALSPLVIQGIRQIPHLLA-YTDSDHYLGFI 71 RN+E+ +L+ +WE +V+ TH FL+ + I + V Q ++ I HL+ + D++ + F+ Sbjct: 9 RNKELIEELISLWENSVKETHSFLSVKEIEDIKQYVPQALKAIEHLIVEFDDNEKPIAFM 68 Query: 72 GVQDTKIEMLFVNPAVRGRGIGKQLVTYAIQTLNVLYVDVNEQNPQAIGFYEHLGFRVFD 131 G+ K+EMLF++P +G+G++L+ AI+ +V + VNEQNPQA GFYEHLGF+V+ Sbjct: 69 GIVGEKLEMLFISPNRMKKGLGRKLLEEAIKNYSVNELVVNEQNPQAKGFYEHLGFKVYK 128 Query: 132 RSERDEQGQPFPILHMKLS 150 R+ DEQG +PIL M L Sbjct: 129 RNPIDEQGNQYPILFMHLG 147 >PA1428 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 143 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 67/141 (47%), Positives = 84/141 (59%), Gaps = 1/141 (0%) Query: 10 ITDRNEEVSHQLLYIWETAVRATHLFLTEQNIAALSPLVIQGIRQIPHLLAYTDSDHYL- 68 I R + + L+ +WE +VRATH FL+E +I L P V + D D Sbjct: 3 IRKRVDADNTALVDLWERSVRATHDFLSEADIVELYPQVRDLYLPAVEVWVLVDDDGVAQ 62 Query: 69 GFIGVQDTKIEMLFVNPAVRGRGIGKQLVTYAIQTLNVLYVDVNEQNPQAIGFYEHLGFR 128 GFIG+ +EMLFV P +RGRGIG++L+ +A T L VDVNEQNPQA GFY H GFR Sbjct: 63 GFIGLNQAHVEMLFVEPGLRGRGIGRRLLDHARATWPRLSVDVNEQNPQACGFYRHYGFR 122 Query: 129 VFDRSERDEQGQPFPILHMKL 149 RS D G+PFP+LHM L Sbjct: 123 QTGRSATDSAGRPFPLLHMSL 143 >PA0249 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 148 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 48/127 (37%), Positives = 61/127 (48%) Query: 22 LYIWETAVRATHLFLTEQNIAALSPLVIQGIRQIPHLLAYTDSDHYLGFIGVQDTKIEML 81 L IW A R H FL E + LV D D LGFIG+ D I L Sbjct: 19 LAIWLEASRVGHGFLGEAELQKQKALVRDHYLDASETWLALDGDTPLGFIGLLDAFIGGL 78 Query: 82 FVNPAVRGRGIGKQLVTYAIQTLNVLYVDVNEQNPQAIGFYEHLGFRVFDRSERDEQGQP 141 FV P GRGIG+QLV +A L V+V N +A+GFY GF R RD++G+ Sbjct: 79 FVAPTAHGRGIGRQLVEHAATLKGALEVEVYAANREALGFYARCGFVESGRRPRDDEGRA 138 Query: 142 FPILHMK 148 I+ ++ Sbjct: 139 LEIVQLR 145 >STM3643 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 146 Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 35/140 (25%), Positives = 62/140 (44%), Gaps = 1/140 (0%) Query: 10 ITDRNEEVSHQLLYIWETAVRATHLFLTEQNIAALSPLVIQGIRQIPHLLAYTDSDHYLG 69 I E +L +W + H F+ E+ +V + ++ G Sbjct: 2 IRKSQSEDMASILALWMKSTIYAHPFIEERYWHESEAIVRDVYLPAAQTWVWEENGQLKG 61 Query: 70 FIGVQDTK-IEMLFVNPAVRGRGIGKQLVTYAIQTLNVLYVDVNEQNPQAIGFYEHLGFR 128 F+ V + + + LFV P GIGK L+ Y Q +L ++V ++N A+ FY LGFR Sbjct: 62 FVSVLEARFVGALFVAPDALRHGIGKALLEYVQQRFPLLSLEVYQKNQSAVNFYHALGFR 121 Query: 129 VFDRSERDEQGQPFPILHMK 148 + D + +++ P I+ + Sbjct: 122 IEDSAWQEDTAHPTWIMSWQ 141 >yiaC [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 146 Score = 53.9 bits (128), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 35/126 (27%), Positives = 57/126 (45%), Gaps = 1/126 (0%) Query: 21 LLYIWETAVRATHLFLTEQNIAALSPLVIQGIRQIPHLLAYTDSDHYLGFIGVQDTK-IE 79 +L +W + H F+ PLV + + LGF+ + + + + Sbjct: 13 ILELWLESTTWGHPFIKANYWRDCIPLVRDAYLANAQNWVWEEDGKLLGFVSIMEGRFLA 72 Query: 80 MLFVNPAVRGRGIGKQLVTYAIQTLNVLYVDVNEQNPQAIGFYEHLGFRVFDRSERDEQG 139 +FV P RGIGK L+ Y Q L ++V ++N AI FY+ GF + D + +DE Sbjct: 73 AMFVAPKAVRRGIGKALMQYVQQRHPHLMLEVYQKNQPAINFYQAQGFHIVDCAWQDETQ 132 Query: 140 QPFPIL 145 P I+ Sbjct: 133 LPTWIM 138 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.140 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 11,194,011 Number of extensions: 441587 Number of successful extensions: 806 Number of sequences better than 1.0e-05: 7 Number of HSP's gapped: 825 Number of HSP's successfully gapped: 7 Length of query: 150 Length of database: 38,378,431 Length adjustment: 97 Effective length of query: 53 Effective length of database: 27,191,033 Effective search space: 1441124749 Effective search space used: 1441124749 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 111 (47.4 bits)