BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0435.0014.p
         (139 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MA0416 [S] COG1917 Uncharacterized conserved protein, contains d...   136   8e-33
MA0402 [S] COG1917 Uncharacterized conserved protein, contains d...   130   5e-31
TM1010 [S] COG1917 Uncharacterized conserved protein, contains d...    92   2e-19
Cgl2167 [S] COG1917 Uncharacterized conserved protein, contains ...    84   9e-17
SMc01911 [S] COG1917 Uncharacterized conserved protein, contains...    72   2e-13

>MA0416 [S] COG1917 Uncharacterized conserved protein, contains
           double-stranded beta-helix domain
          Length = 141

 Score =  136 bits (343), Expect = 8e-33,   Method: Compositional matrix adjust.
 Identities = 71/130 (54%), Positives = 90/130 (69%), Gaps = 7/130 (5%)

Query: 3   KHDEVKNGIIFPVGEK-NEAFAQYFVGQSYLSTLVA-DPNVNVGVGNVTFEPGCRNNWHI 60
           K + +   +IFP GE+  E F++YF G+++LS LV  D   N  +GNVTFEPGCRNNWH 
Sbjct: 3   KSNNLSESVIFPKGEELPEMFSKYFSGKAWLSMLVPRDNEFNCPIGNVTFEPGCRNNWHK 62

Query: 61  HRNGFQLLMVTGGEGWYQEEGKPAQFLKAGDVVVTQDGVKHWHGASKDSWFEHIA----I 116
           H  G Q+L+VTGG G+YQEEGK AQ L  GD+V     VKHWHGA+ DSWF H++    +
Sbjct: 63  HPGG-QILLVTGGRGYYQEEGKLAQELNPGDIVKIHPNVKHWHGAAHDSWFVHLSVETNV 121

Query: 117 TAGRPEWLEP 126
           +AG  EWLEP
Sbjct: 122 SAGTAEWLEP 131


>MA0402 [S] COG1917 Uncharacterized conserved protein, contains
           double-stranded beta-helix domain
          Length = 141

 Score =  130 bits (328), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 68/132 (51%), Positives = 89/132 (67%), Gaps = 7/132 (5%)

Query: 1   VAKHDEVKNGIIFPVGEK-NEAFAQYFVGQSYLSTLVA-DPNVNVGVGNVTFEPGCRNNW 58
           ++  + +   +IFP GE+  E  ++YF G+ ++S LV  D   N  +GNVTFEPGC NNW
Sbjct: 1   MSDSNNLSESVIFPKGEELPEFLSKYFSGKVWVSMLVGRDNEFNCPIGNVTFEPGCINNW 60

Query: 59  HIHRNGFQLLMVTGGEGWYQEEGKPAQFLKAGDVVVTQDGVKHWHGASKDSWFEHIAI-- 116
           H H  G Q+L+VTGG G+YQEEGKPA+ LK GD+V     VKHWHGA+ DSWF H+++  
Sbjct: 61  HKHPGG-QILLVTGGRGYYQEEGKPARELKPGDIVTIAPDVKHWHGAAHDSWFVHLSVET 119

Query: 117 --TAGRPEWLEP 126
              AG  EWLEP
Sbjct: 120 NANAGPAEWLEP 131


>TM1010 [S] COG1917 Uncharacterized conserved protein, contains
           double-stranded beta-helix domain
          Length = 135

 Score = 92.4 bits (228), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 55/119 (46%), Positives = 68/119 (57%), Gaps = 9/119 (7%)

Query: 12  IFPVGEKNEAFAQYFVGQSYLSTLVADPN--VNVGVGNVTFEPGCRNNWHIHRNGFQLLM 69
           IF  G K  +   +F G  ++  LV D N   N  V +V FEPG R +WH H  G Q+L+
Sbjct: 5   IFERGSKGSS--DFFTGNVWVKMLVTDENGVFNTQVYDVVFEPGARTHWHSHPGG-QILI 61

Query: 70  VTGGEGWYQEEGKPAQFLKAGDVVVTQDGVKHWHGASKDSWFEHIAITA----GRPEWL 124
           VT G+G+YQE GKPA+ LK GDVV     V HWHGA+ D    HI I+     G  EWL
Sbjct: 62  VTRGKGFYQERGKPARILKKGDVVEIPPNVVHWHGAAPDEELVHIGISTQVHLGPAEWL 120


>Cgl2167 [S] COG1917 Uncharacterized conserved protein, contains
           double-stranded beta-helix domain
          Length = 133

 Score = 83.6 bits (205), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 47/106 (44%), Positives = 65/106 (61%), Gaps = 5/106 (4%)

Query: 11  IIFPVGEKNEAFAQYFVGQSYLSTLVADPNVNVGVGNVTFEPGCRNNWHIHRNGFQLLMV 70
           I FP+G  N A AQ+F G+ +++ L  D NV +   NV+FE G R NWH H  G Q ++V
Sbjct: 3   IEFPLG--NPAPAQWFSGEVHMAKL--DDNVQIETVNVSFEAGGRTNWHTHPVG-QNIIV 57

Query: 71  TGGEGWYQEEGKPAQFLKAGDVVVTQDGVKHWHGASKDSWFEHIAI 116
             G G Y+ EG+PA+ L+ GDVV    GV+HWHGA   +   H+ +
Sbjct: 58  LSGLGIYEAEGEPARLLEPGDVVFAAAGVRHWHGAVSGAPMFHVVV 103


>SMc01911 [S] COG1917 Uncharacterized conserved protein, contains
           double-stranded beta-helix domain
          Length = 132

 Score = 72.4 bits (176), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 45/108 (41%), Positives = 56/108 (51%), Gaps = 4/108 (3%)

Query: 12  IFPVGEKNEAF--AQYFVGQSYLSTLVADPN-VNVGVGNVTFEPGCRNNWHIHRNGFQLL 68
           IF  G +  A   A+YF G   +      P+   V    VTFEPG R  WH H  G Q L
Sbjct: 3   IFECGSRPSARGPAEYFTGSVRVDPAFEAPSPARVRGATVTFEPGARTAWHTHPLG-QTL 61

Query: 69  MVTGGEGWYQEEGKPAQFLKAGDVVVTQDGVKHWHGASKDSWFEHIAI 116
           +VT G G  Q  G   + ++AGDVV    G KHWHGA+ ++   HIAI
Sbjct: 62  IVTAGRGLAQSWGGELREIRAGDVVWFPPGEKHWHGAASETGMTHIAI 109


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.317    0.137    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 11,416,737
Number of extensions: 486243
Number of successful extensions: 1660
Number of sequences better than 1.0e-05: 7
Number of HSP's gapped: 1656
Number of HSP's successfully gapped: 7
Length of query: 139
Length of database: 38,378,431
Length adjustment: 95
Effective length of query: 44
Effective length of database: 27,421,701
Effective search space: 1206554844
Effective search space used: 1206554844
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 110 (47.0 bits)