BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0435.0004.p (182 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ywrO [R] COG2249 Putative NADPH-quinone reductase (modulator ... 204 6e-53 BS_yrkL [R] COG2249 Putative NADPH-quinone reductase (modulator ... 191 4e-49 BS_ydeQ [R] COG2249 Putative NADPH-quinone reductase (modulator ... 170 1e-42 lin1898 [R] COG2249 Putative NADPH-quinone reductase (modulator ... 161 5e-40 CC0205 [R] COG2249 Putative NADPH-quinone reductase (modulator o... 142 2e-34 >BS_ywrO [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 204 bits (519), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 11/174 (6%), Positives = 29/174 (16%), Gaps = 1/174 (0%) Query: 1 MKTLVLVFHPDLIASRVNRRLTDEMEKQDGVTVHRVYEVYPDEKIDVSAEHRLLEQHDRI 60 M+ + +++ +T + + ++ + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 61 VLQFPFYWYSTPSLLKKWEDAVLTYGWAYGSKGNKLHGKELLIAVSTGAAQENYRPDGNF 120 + + ++ G N G A+ +E Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 121 KYTVPELLRPFQATSNLIGTRYLEPFIVYGVMQHLSDEELEQSAKEYVAYALNP 174 T L + A A Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDS-APAVSLLDTLDALAEYQRAGKI 173 >BS_yrkL [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 191 bits (486), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 10/170 (5%), Positives = 28/170 (16%), Gaps = 1/170 (0%) Query: 1 MKTLVLVFHPDLIASRVNRRLTDEMEKQDGVTVHRVYEVYPDEKIDVSAEHRLLEQHDRI 60 M+ + +++ +T + + ++ + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 61 VLQFPFYWYSTPSLLKKWEDAVLTYGWAYGSKGNKLHGKELLIAVSTGAAQENYRPDGNF 120 + + ++ G N G A+ +E Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 121 KYTVPELLRPFQATSNLIGTRYLEPFIVYGVMQHLSDEELEQSAKEYVAY 170 T L + A Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSA-PAVSLLDTLDALAEYQR 169 >BS_ydeQ [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 170 bits (431), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 9/176 (5%), Positives = 29/176 (16%), Gaps = 1/176 (0%) Query: 1 MKTLVLVFHPDLIASRVNRRLTDEMEKQDGVTVHRVYEVYPDEKIDVSAEHRLLEQHDRI 60 + + E + + + Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 61 VLQFPFYWYSTPSLLKKWEDAVLTYGWAYGSKGNKLHGKELLIAVSTGAAQENYRPDGNF 120 + + + ++ + + + L + A + Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQT 123 Query: 121 KYTVPELLRPFQATSNLIGTRYLEPFIVYGVMQHLSDEELEQSAKEYVAYALNPEL 176 Y + Q +N G L D + + + Sbjct: 124 DYLDLYQVHWPQRPTNCFGKLGYSWTDSAPA-VSLLDTLDALAEYQRAGKIRYIGV 178 >lin1898 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 161 bits (407), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 14/168 (8%), Positives = 38/168 (22%), Gaps = 1/168 (0%) Query: 1 MKTLVLVFHPDLIASRVNRRLTDEMEKQ-DGVTVHRVYEVYPDEKIDVSAEHRLLEQHDR 59 M+ + +++ +T + Y V + AE + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 60 IVLQFPFYWYSTPSLLKKWEDAVLTYGWAYGSKGNKLHGKELLIAVSTGAAQENYRPDGN 119 Y + + E ++ + S+ N + + + Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 120 FKYTVPELLRPFQATSNLIGTRYLEPFIVYGVMQHLSDEELEQSAKEY 167 + +L + L + L+ A+ Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQ 168 >CC0205 [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B) Length = 346 Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 9/167 (5%), Positives = 30/167 (17%), Gaps = 1/167 (0%) Query: 3 TLVLVFHPDLIASRVNRRLTDEMEKQDGVTVHRVYEVYPDEKIDVSAEHRLLEQHDRIVL 62 L + + E + + + + ++ E Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 63 QFPFYWYSTPSLLKKWEDAVLTYGWAYGSKGNKLHGKELLIAVSTGAAQENYRPDGNFKY 122 + S K + ++ KG + + R ++ Sbjct: 68 YVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD 127 Query: 123 TVPELLRPFQATSNLIGTRYLEPFIVYGVMQHLSDEELEQSAKEYVA 169 + + + L + + Sbjct: 128 LYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLD-TLDALAEYQRAGKI 173 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,304,009 Number of extensions: 583199 Number of successful extensions: 963 Number of sequences better than 1.0e-05: 27 Number of HSP's gapped: 960 Number of HSP's successfully gapped: 27 Length of query: 182 Length of database: 38,378,431 Length adjustment: 100 Effective length of query: 82 Effective length of database: 26,845,031 Effective search space: 2201292542 Effective search space used: 2201292542 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 112 (47.8 bits)