BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0434.0008.p
         (71 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SA0992 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins         88   3e-18
SPy1835 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins        87   9e-18
BS_trxA [OC] COG0526 Thiol-disulfide isomerase and thioredoxins        86   1e-17
L0195 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins          82   3e-16
DR0944 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins         81   3e-16

>SA0992 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
          Length = 104

 Score = 88.2 bits (217), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 41/70 (58%), Positives = 53/70 (75%)

Query: 1   MLAPILEELSTELGDDVKIAKLNVDENPETASRFGVMSIPTLIFFKDGQPVDKVVGLNSK 60
           M+AP+LEEL+ +      I KL+VDENP TA+++ VMSIPTLI FKDGQPVDKVVG   K
Sbjct: 34  MIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPK 93

Query: 61  DSLKNIVAKH 70
           ++L  ++ KH
Sbjct: 94  ENLAEVLDKH 103


>SPy1835 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
          Length = 104

 Score = 86.7 bits (213), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 42/70 (60%), Positives = 58/70 (82%), Gaps = 1/70 (1%)

Query: 1   MLAPILEELSTELGDD-VKIAKLNVDENPETASRFGVMSIPTLIFFKDGQPVDKVVGLNS 59
           M APILE+LS E+ +D +KI K++VDENPETA +FG+MSIPTL+F KDG+ V +V G+++
Sbjct: 33  MQAPILEQLSQEIDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHT 92

Query: 60  KDSLKNIVAK 69
           KD LK I+A+
Sbjct: 93  KDQLKAIIAE 102


>BS_trxA [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
          Length = 127

 Score = 86.3 bits (212), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 2/70 (2%), Positives = 11/70 (15%)

Query: 1   MLAPILEELSTELGDDVKIAKLNVDENPETASRFGVMSIPTLIFFKDGQPVDKVVGLNSK 60
            +      +  +   +       +    +  +      +       D  P          
Sbjct: 34  DVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRG 93

Query: 61  DSLKNIVAKH 70
                +    
Sbjct: 94  IPTLLLFKNG 103


>L0195 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
          Length = 104

 Score = 81.6 bits (200), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 39/70 (55%), Positives = 55/70 (78%), Gaps = 1/70 (1%)

Query: 1   MLAPILEELSTELGD-DVKIAKLNVDENPETASRFGVMSIPTLIFFKDGQPVDKVVGLNS 59
           M APILE+LS EL + ++KI K++VDENP TA  FG+MSIPTL+F KDG+ V ++VG+ +
Sbjct: 33  MQAPILEQLSEELDESELKICKMDVDENPATAQGFGIMSIPTLMFKKDGEEVKRIVGVQT 92

Query: 60  KDSLKNIVAK 69
           K  LK ++A+
Sbjct: 93  KAQLKAVIAE 102


>DR0944 [OC] COG0526 Thiol-disulfide isomerase and thioredoxins
          Length = 141

 Score = 81.3 bits (199), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 35/70 (50%), Positives = 54/70 (77%)

Query: 1   MLAPILEELSTELGDDVKIAKLNVDENPETASRFGVMSIPTLIFFKDGQPVDKVVGLNSK 60
           ++AP++EEL+ +    VK+AK+NVD+NP T+ +F VMSIPT+I FKDGQPV+ +VG   K
Sbjct: 66  IIAPVIEELAGQYEGRVKVAKVNVDDNPATSGQFRVMSIPTMILFKDGQPVEGMVGAQPK 125

Query: 61  DSLKNIVAKH 70
            + ++++ KH
Sbjct: 126 RAFESVLDKH 135


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.314    0.134    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 5,137,317
Number of extensions: 153635
Number of successful extensions: 397
Number of sequences better than 1.0e-05: 88
Number of HSP's gapped: 395
Number of HSP's successfully gapped: 88
Length of query: 71
Length of database: 38,378,431
Length adjustment: 42
Effective length of query: 29
Effective length of database: 33,534,403
Effective search space: 972497687
Effective search space used: 972497687
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 109 (46.6 bits)