BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0420.0038.p (339 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1721 [K] COG1609 Transcriptional regulators 164 2e-40 PA1949 [K] COG1609 Transcriptional regulators 159 4e-39 RSc1014 [K] COG1609 Transcriptional regulators 158 2e-38 CAC0856 [K] COG1609 Transcriptional regulators 155 1e-37 TM1200 [K] COG1609 Transcriptional regulators 151 2e-36 >VC1721 [K] COG1609 Transcriptional regulators Length = 336 Score = 164 bits (414), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 95/315 (30%), Positives = 175/315 (55%), Gaps = 10/315 (3%) Query: 4 TITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSSSNI 63 TI D+A AGV+ +TVS V+N + +++ T++KV E +KQ+NY PS++A L ++ I Sbjct: 3 TIKDVARLAGVSTTTVSHVINKTRFVAETTQEKVMEAVKQLNYAPSAVARSLKCNTTRTI 62 Query: 64 GLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSKRVD 123 G+L+ S N FF +I G+ES Y L + N + R++ KRVD Sbjct: 63 GMLVTQST-----NLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKRVD 117 Query: 124 GLIANTSVLTEELCTRLN-HLEFPYVSLG---EVAASGCWVDFDNEAGGRMLTRHLLEEG 179 G++ S LT+EL L+ H + P V + E + + +D ++E GG + T++L + G Sbjct: 118 GILVMCSDLTQELQDMLDAHKDIPKVVMDWGPETSHADKIID-NSEEGGYLATKYLTDRG 176 Query: 180 YSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLLSE 239 ++ +A + G+ R++G R+ + +A + ++WI+ G E AA +++ + Sbjct: 177 HTEIACLSGHFVKAACQERIQGFRRAMAEAKLTVNEDWILEGNFECDTAVLAADKIIAMD 236 Query: 240 TPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTFHL 299 P +V C ++ A G++ ++ G+++P + + +D+ L+ Y SPPLT+++ + Sbjct: 237 KRPTAVFCFNDTMALGLMSRLQQKGIRIPEDMSVIGYDNIELAEYFSPPLTTVHQPKRRV 296 Query: 300 GVSAGKLLMERIGGK 314 G +A ++L+ERI K Sbjct: 297 GKNAFEILLERIKDK 311 >PA1949 [K] COG1609 Transcriptional regulators Length = 337 Score = 159 bits (403), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 107/333 (32%), Positives = 171/333 (51%), Gaps = 8/333 (2%) Query: 4 TITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSSSNI 63 T+ D+A AGV+ +TVS V+N + +S ++KV + + Q++Y PS++A L +++S I Sbjct: 3 TMKDVAAMAGVSFTTVSHVVNRTRPVSDAVRKKVEDAIAQLHYVPSAVARSLKVRTTSII 62 Query: 64 GLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSKRVD 123 GLL+ S N +F + GIE Y + + N + N R+++ KR+D Sbjct: 63 GLLVPNST-----NPYFAELSRGIEDCCERNGYCVILCNSDDNPQKQANYLRVLQEKRID 117 Query: 124 GLIANTSVLTEELCTRLNHLEFPYVSLG-EV-AASGCWVDFDNEAGGRMLTRHLLEEGYS 181 GL+ ++ L L ++ P V + EV V D+E G + TRHLLE G+ Sbjct: 118 GLVLASAGGDGALAKGLANMRTPTVIVDREVEGVEADRVQIDHEMGAYLATRHLLELGHR 177 Query: 182 AVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLLSE-T 240 +A IGG + R+EG R+ + +AG +R +W++ E GY AA LL E Sbjct: 178 DIACIGGPLSTKVSTLRVEGYRRAMAKAGLEVRPQWLLESEFSSPGGYHAALGLLGGEGE 237 Query: 241 PPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTFHLG 300 P +++ ++ GVL AA EL ++VP +L + FDD LSR+ P LT++ LG Sbjct: 238 RPTAIVAGNDMIGIGVLRAAAELNIRVPHELSVIGFDDIELSRFVFPALTTVGQSIRLLG 297 Query: 301 VSAGKLLMERIGGKNXXXXXXXXXXXXXXRESS 333 A +LL++RI + RES+ Sbjct: 298 EIAAQLLLQRIAEREEPMQRRVVAPALVLREST 330 >RSc1014 [K] COG1609 Transcriptional regulators Length = 347 Score = 158 bits (399), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 98/311 (31%), Positives = 158/311 (50%), Gaps = 9/311 (2%) Query: 4 TITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSSSNI 63 TI D+A AGV+ +TVS V+N++ ++ ET+++V E ++ Y PS++A L +++ I Sbjct: 3 TIKDVAALAGVSFTTVSHVINNTRPVNSETRKRVEEAIRATRYVPSAVARSLKHRTTRTI 62 Query: 64 GLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSKRVD 123 G+L+ + N +F + GIE V + Y + + N + + R++ KRVD Sbjct: 63 GVLVPTAT-----NPYFAELARGIEDVCAAAGYSVILCNSDDDPRKQRDYLRVLMEKRVD 117 Query: 124 GLIANTSVLTEELCTRLNHLEFPYVSLGEVAASGCWVD---FDNEAGGRMLTRHLLEEGY 180 GLI +++ L L P V + + G D D+E G + TRHLLE G+ Sbjct: 118 GLIVSSAGPDNALLDALGESALPVVMV-DRPTEGILADQVQIDHEEGAYLATRHLLELGH 176 Query: 181 SAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLLSET 240 +A I G + RL G + L +AG P + G+ GY+AA++LL + Sbjct: 177 RRIACISGPSTLSVTAGRLAGFHRALREAGVPEHAARVAEGDFTSPGGYRAARELLTTGE 236 Query: 241 PPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTFHLG 300 P ++ ++ G L AA ELG+ VP +L I FDD LSRY P L+++ LG Sbjct: 237 TPTAIFASNDLMGIGALRAAAELGIAVPKELSIIGFDDIELSRYVYPALSTVGQSIRQLG 296 Query: 301 VSAGKLLMERI 311 + L+E + Sbjct: 297 ETTASTLLEHL 307 >CAC0856 [K] COG1609 Transcriptional regulators Length = 346 Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 102/315 (32%), Positives = 168/315 (53%), Gaps = 7/315 (2%) Query: 1 MKVTITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSS 60 M TI D+A A V+ STVS+VLNDS KIS ETK++V + +K+++Y ++IA LA S+ Sbjct: 12 MAATIRDVAKLANVSPSTVSRVLNDSNKISCETKERVIKAIKKLDYHANAIARSLANNST 71 Query: 61 SNIGLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSK 120 +GL++ + F N FF + GI +Y + + + + V+SK Sbjct: 72 KILGLIVPNEAKNLFRNPFFIKAMRGISLCAHENEYYIMYDFGSSEKEEVSLIKKYVQSK 131 Query: 121 RVDGLIANTSVLTEELCTRLNHLEFPYVSLG--EVAASGCWVDFDNEAGGRMLTRHLLEE 178 VDG+I T ++ L L++P+V +G E + WVD DN L L++ Sbjct: 132 LVDGIILLTVRKNDKCIDFLKRLKYPFVVIGRPEESKGVMWVDNDNFKAMYDLVDGLIKR 191 Query: 179 GYSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEA-EEAFGYQAAKQLLL 237 G ++AFIG + + RL+G ++ L G+ + +E I+ ++ E GY A K++L Sbjct: 192 GAESIAFIGAAKEMNMSRDRLDGYKRALLAHGREVDEEIIVEQKSFTEEEGYTAMKKILE 251 Query: 238 SETPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTF 297 +TP V+ + A+GVL RE+G + + F++ PL Y +PPL S++++ Sbjct: 252 VKTPS-LVVTTDDLLAFGVLKLLREIG---EESISVVGFNNIPLGEYQNPPLASVDINAE 307 Query: 298 HLGVSAGKLLMERIG 312 LG A KLL++ + Sbjct: 308 KLGYHAAKLLIDSVN 322 >TM1200 [K] COG1609 Transcriptional regulators Length = 333 Score = 151 bits (381), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 88/311 (28%), Positives = 164/311 (52%), Gaps = 11/311 (3%) Query: 3 VTITDIAIAAGVAKSTVSKVLNDSPKISQETKQKVREIMKQMNYTPSSIATGLARQSSSN 62 VTI DIA AGV+ +TVS+ LN+ P IS+ET++K+ +I +++ Y ++ A+ L + ++ Sbjct: 6 VTIRDIAEKAGVSINTVSRALNNKPDISEETRRKILKIAQELGYVKNATASSLRSKQTNI 65 Query: 63 IGLLIDMSKSSEFLNQFFYNIIGGIESVIGSLKYELTIANVEHNHPDGHFLHRLVRSKRV 122 +G++I ++ N F+ ++ GIE+ Y++ + N E + + ++ +RV Sbjct: 66 VGVII-----ADSANPFYAEVLKGIEAASRKYGYQIMLMNTERIYENEEKAIEVLLQRRV 120 Query: 123 DGLIANTSVLTEELCTRLNHLEFPYVSLG----EVAASGCWVDFDNEAGGRMLTRHLLEE 178 DGL+ + L + P+V +G E+ + D GG + TRHL+E Sbjct: 121 DGLLITPVQDRSDDIKTLIERKVPFVIVGRHFEELEVD--EIHSDEVKGGYLATRHLIER 178 Query: 179 GYSAVAFIGGYEGDPLFIRRLEGCRQVLGQAGKPLRKEWIINGEAEEAFGYQAAKQLLLS 238 G + I GY RLEG R+ L + G P ++ II + + GY+A ++ + Sbjct: 179 GRKNIIMISGYLFKSAAYMRLEGYRKALKEYGIPFSEKMIIETDIDIESGYRAMREAIEK 238 Query: 239 ETPPDSVICMSNFAAYGVLLAARELGVKVPTQLGIATFDDYPLSRYTSPPLTSLNLDTFH 298 ++V C ++ A+GV+ A +E G ++P + + +DD S + P LT++ + F Sbjct: 239 GLEFEAVFCYNDLLAFGVIKALKECGYRIPEDVAVVGYDDIVYSSFICPSLTTVRIKKFE 298 Query: 299 LGVSAGKLLME 309 +G A ++L++ Sbjct: 299 MGFEAFRMLLQ 309 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,602,829 Number of extensions: 946832 Number of successful extensions: 2614 Number of sequences better than 1.0e-05: 170 Number of HSP's gapped: 2335 Number of HSP's successfully gapped: 171 Length of query: 339 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 232 Effective length of database: 26,037,693 Effective search space: 6040744776 Effective search space used: 6040744776 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)