BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0420.0020.p
         (491 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BS_yvjB [M] COG0793 Periplasmic protease                              189   7e-48
all3420 [M] COG0793 Periplasmic protease                              180   4e-45
BS_ctpA [M] COG0793 Periplasmic protease                              180   5e-45
XF2704 [M] COG0793 Periplasmic protease                               178   2e-44
PA5134 [M] COG0793 Periplasmic protease                               176   7e-44

>BS_yvjB [M] COG0793 Periplasmic protease
          Length = 480

 Score =  189 bits (481), Expect = 7e-48,   Method: Compositional matrix adjust.
 Identities = 120/342 (35%), Positives = 188/342 (54%), Gaps = 18/342 (5%)

Query: 38  VPGTDQAQAA--ASTDRINEIMQYLEQYNVEGIDQDTLIRGAIDGMVNTLNDPYSQYFDK 95
           VP T QA +    + D+I +  + +    VE +D++ L+ GAI GM++TLNDPYS Y DK
Sbjct: 38  VPATAQADSERDKAMDKIEKAYELISNEYVEKVDREKLLEGAIQGMLSTLNDPYSVYMDK 97

Query: 96  DEAAAFSHAVDLEYVGIGIRMVYTAKELYIEEVVAGSPAEQAGLKRGDTILKINGVKIQD 155
             A  FS ++D  + GIG  +     ++ I      SPAE+AGLK  D I+ ING   + 
Sbjct: 98  QTAKQFSDSLDSSFEGIGAEVGMEDGKIIIVSPFKKSPAEKAGLKPNDEIISING---ES 154

Query: 156 TKGDELS-------GTAGTKVSLLVSRKGVLK--TFSVKRSEMASTSV---TSKMLGQNI 203
             G +L+       G  G+ VS+ + R G  K  +F +KR+E+   +V     K+ G ++
Sbjct: 155 MAGKDLNHAVLKIRGKKGSSVSMKIQRPGTKKQLSFRIKRAEIPLETVFASEKKVQGHSV 214

Query: 204 AYISIGGFTQNADEEFTAALDKMRAGGMKSLVLDLRDNTGGYMDSAYNIASQFMDKG-IM 262
            YI+I  F+++  E+F  AL ++    ++ LV+D+R N GGY+ S   I   F+ K    
Sbjct: 215 GYIAISTFSEHTAEDFAKALRELEKKEIEGLVIDVRGNPGGYLQSVEEILKHFVTKDQPY 274

Query: 263 MYTSDQSGALTPVTITNGSKIGVPVVVLTNEYTASASEALTGALHDNKLATVVGTRSFGK 322
           +  ++++G       T   K   PV V+T++ +ASASE L GAL +     VVG  SFGK
Sbjct: 275 IQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSASASEILAGALKEAGHYDVVGDTSFGK 334

Query: 323 ARIQSLIPVSDGAELKLTTQKYLTPSKEDFNHIGLSPDIEVQ 364
             +Q  +P+ DG+ +KLT  K+LTP+    +  G+ P I ++
Sbjct: 335 GTVQQAVPMGDGSNIKLTLYKWLTPNGNWIHKKGIEPTIAIK 376


>all3420 [M] COG0793 Periplasmic protease
          Length = 417

 Score =  180 bits (457), Expect = 4e-45,   Method: Compositional matrix adjust.
 Identities = 108/313 (34%), Positives = 171/313 (54%), Gaps = 14/313 (4%)

Query: 76  GAIDGMVNTLNDPYSQYFDKDEAAAFSHAVDLEYVGIGIRMVYTAKELYIEEV--VAGSP 133
           GAI  M+ TL DP++++ D ++  +       E  G+G+++    +   +E V  +AGSP
Sbjct: 81  GAIQNMLKTLGDPFTRFLDPEQYRSLQVNTSGELTGVGLQIALNPQSGKLEVVSPIAGSP 140

Query: 134 AEQAGLKRGDTILKINGVKIQDTKGDE----LSGTAGTKVSLLVSRKGV-LKTFSVKRSE 188
           A+QAG+K  D I+KI G+   D   DE    + G  G+ V+L++ R G   K   + R  
Sbjct: 141 ADQAGIKPRDRIVKIEGISTTDLTLDEAATRMRGPIGSLVTLVIERDGEGEKEIRIVRDR 200

Query: 189 MASTSVTSKML----GQNIAYISIGGFTQNADEEFTAALDKMRAGGMKSLVLDLRDNTGG 244
           +A   V +++     G++  Y+ +  F  NA  E   A+  +   G  + +LDLR+N GG
Sbjct: 201 IALNPVVAELRSSPEGKSFGYLRLTQFNANASMELAHAISSLEKKGAAAYILDLRNNPGG 260

Query: 245 YMDSAYNIASQFMDKGIMMYTSDQSGALTPVTITNGSKIGVPVVVLTNEYTASASEALTG 304
            + +   IA Q++D G ++YT ++ G          +    P+++L N+ TASASE L G
Sbjct: 261 LLQAGIEIARQWLDSGTIVYTVNRQGIQGSFEAFGPALTDDPLIILVNQGTASASEILAG 320

Query: 305 ALHDNKLATVVGTRSFGKARIQSLIPVSDGAELKLTTQKYLTPSKEDFNHIGLSPDIEVQ 364
           AL DN  A +VG  +FGK  IQSL  +SDG+ L +T  KY TP+  D N +G+ P+  V 
Sbjct: 321 ALQDNGRAQLVGETTFGKGLIQSLFELSDGSGLAVTIAKYETPNHRDINKLGIKPNTVV- 379

Query: 365 GKTAQLITALQIA 377
             T Q++T  +IA
Sbjct: 380 --TQQILTRDEIA 390


>BS_ctpA [M] COG0793 Periplasmic protease
          Length = 466

 Score =  180 bits (456), Expect = 5e-45,   Method: Compositional matrix adjust.
 Identities = 113/331 (34%), Positives = 184/331 (55%), Gaps = 11/331 (3%)

Query: 45  QAAAST-----DRINEIMQYLEQYNVEGIDQDTLIRGAIDGMVNTLNDPYSQYFDKDEAA 99
           Q +AST     D++N+  + ++    +  D D L+ GAI GM+ +L+DPYS Y D+++A 
Sbjct: 34  QKSASTGDSKFDKLNKAYEQIKSDYYQKTDDDKLVDGAIKGMIQSLDDPYSTYMDQEQAK 93

Query: 100 AFSHAVDLEYVGIGIRMVYTAKELYIEEVVAGSPAEQAGLKRGDTILKINGVKIQDTKGD 159
           +F   +   + GIG ++     E+ I   + GSPAE+AG+K  D I+K+NG  ++    +
Sbjct: 94  SFDETISASFEGIGAQVEEKDGEILIVSPIKGSPAEKAGIKPRDQIIKVNGKSVKGMNVN 153

Query: 160 E----LSGTAGTKVSLLVSRKGVLKT-FSVKRSEMASTSVTSKMLGQNIAYISIGGFTQN 214
           E    + G  GTKV L ++R GV     S+KR  +   +V S+M   NI  I I  F++ 
Sbjct: 154 EAVALIRGKKGTKVKLELNRAGVGNIDLSIKRDTIPVETVYSEMKDNNIGEIQITSFSET 213

Query: 215 ADEEFTAALDKMRAGGMKSLVLDLRDNTGGYMDSAYNIASQFMDKGI-MMYTSDQSGALT 273
             +E T A+D +   G K  +LDLR N GG M+ A  +++ F+DKG  +M    ++G+  
Sbjct: 214 TAKELTDAIDSLEKKGAKGYILDLRGNPGGLMEQAITMSNLFIDKGKNIMQVEYKNGSKE 273

Query: 274 PVTITNGSKIGVPVVVLTNEYTASASEALTGALHDNKLATVVGTRSFGKARIQSLIPVSD 333
            +      K+  P VVL N+ TASA+E +  ALH++    ++G  +FGK  +Q+     D
Sbjct: 274 VMKAEKERKVTKPTVVLVNDGTASAAEIMAAALHESSNVPLIGETTFGKGTVQTAKEYDD 333

Query: 334 GAELKLTTQKYLTPSKEDFNHIGLSPDIEVQ 364
           G+ +KLT  K+LT   E  +  G+ P ++ +
Sbjct: 334 GSTVKLTVAKWLTADGEWIHKKGIKPQVKAE 364


>XF2704 [M] COG0793 Periplasmic protease
          Length = 508

 Score =  178 bits (451), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 117/341 (34%), Positives = 189/341 (55%), Gaps = 19/341 (5%)

Query: 39  PGTDQAQAAASTD---RINEIMQYLEQYN------VEGIDQDTLIRGAIDGMVNTLNDPY 89
           P  ++ +   S D    ++EI +++  YN      V+ ++   L+  A+ G+++ L DP+
Sbjct: 55  PPVEEMEMPESNDANVPLDEIRRFVSVYNAIKQAYVDPVNDRKLMHSAVRGLLSDL-DPH 113

Query: 90  SQYFDKDEAAAFSHAVDLEYVGIGIRMVYTAKE-LYIEEVVAGSPAEQAGLKRGDTILKI 148
           S YFDK++A AF    +  Y GIG+ +   +   L +   +  +PA +AGL+ GD I+ I
Sbjct: 114 STYFDKEDADAFDEQTNGVYDGIGVELQEQSDNTLKVIAPIDDTPAARAGLRPGDLIVAI 173

Query: 149 NGVKIQDTKG-DELSGTAGTKVSLLVSRKGVLKTF--SVKRSEMASTSVTSKMLGQNIAY 205
           NG  + +      L G  G++V+L + R    K F  ++KR  +   SV S+ML     Y
Sbjct: 174 NGKPLANVDAMKPLRGAPGSQVTLTIVRDKNGKPFDMTIKRETIHIASVRSRMLEPGYGY 233

Query: 206 ISIGGFTQNADEEFTAALDKMR--AGG-MKSLVLDLRDNTGGYMDSAYNIASQFMDKGIM 262
           I I  F  +   +F   L +++  AGG ++ L+LDLR N GG + +A  +A   +DKG +
Sbjct: 234 IRISVFQADTGNDFHKHLGQLKQQAGGKLRGLLLDLRSNPGGLLTAAVQVADALLDKGNI 293

Query: 263 MYTSDQ-SGALTPVTITNGSKI-GVPVVVLTNEYTASASEALTGALHDNKLATVVGTRSF 320
           + T  + S + T    T G  + G+P+VVL +  +ASASE L GAL DN  A V+G+ +F
Sbjct: 294 VSTRGRISASDTRFDATPGDLLDGLPLVVLVDAGSASASEVLVGALSDNHRARVIGSCTF 353

Query: 321 GKARIQSLIPVSDGAELKLTTQKYLTPSKEDFNHIGLSPDI 361
           GK  +Q+L+P+ +G  +KLTT +Y TPS       G+ PD+
Sbjct: 354 GKGSVQTLLPLDNGDSVKLTTARYYTPSGRSIQARGIVPDL 394


>PA5134 [M] COG0793 Periplasmic protease
          Length = 436

 Score =  176 bits (447), Expect = 7e-44,   Method: Compositional matrix adjust.
 Identities = 116/327 (35%), Positives = 183/327 (55%), Gaps = 27/327 (8%)

Query: 55  EIMQYLEQYNVEGIDQDTLIRGAIDGMVNTLNDPYSQYFDKDEAAAFSHAVDLEYVGIGI 114
           E++  ++   VE +D  TL+  AI GM++ L DP+S Y   ++ A    +   E+ G+GI
Sbjct: 51  EVLDRVKAAYVEPVDDKTLLENAIKGMLSNL-DPHSAYLGPEDFAELQESTSGEFGGLGI 109

Query: 115 RMVYTAKELYIEEVVAGSPAEQAGLKRGDTILKINGVKIQDTKG-------DELSGTAGT 167
            +      + +   +  +PA +AG++ GD I++I+G   + TKG       D + G AG+
Sbjct: 110 EVGSEDGFIKVVSPIDDTPAARAGIQPGDLIVQIDG---KPTKGQSMTEAVDSMRGKAGS 166

Query: 168 KVSLLVSRKGVLKTFSV--KRSEMASTSVTSKMLGQNIAYISIGGFTQNADEEFTAALDK 225
            ++L + R G  + F V  KR+ +   SV S++L    AY+ I  F  N  EE   AL++
Sbjct: 167 PITLTIVRDGG-RPFDVELKRAIIKVKSVKSQVLEPGYAYLRITQFQVNTGEEVVKALNQ 225

Query: 226 MRA---GGMKSLVLDLRDNTGGYMDSAYNIASQFMDKGIMMYT------SDQSGALTPVT 276
           +R    G +K LVLDLR+N GG + SA  +A  F+ KG+++YT      S+   +  P  
Sbjct: 226 LRKDNKGRLKGLVLDLRNNPGGVLQSAVEVADAFLTKGLIVYTKGRIANSELRFSADPAD 285

Query: 277 ITNGSKIGVPVVVLTNEYTASASEALTGALHDNKLATVVGTRSFGKARIQSLIPVSDGAE 336
            ++     VP+VVL N  +ASA+E + GAL D K A ++GT SFGK  +Q+++P+++   
Sbjct: 286 PSDK----VPLVVLINGGSASAAEIVAGALQDQKRAILMGTDSFGKGSVQTVLPLNNDRA 341

Query: 337 LKLTTQKYLTPSKEDFNHIGLSPDIEV 363
           LKLTT  Y TP+       G+ PDIEV
Sbjct: 342 LKLTTALYYTPNGRSIQAQGIVPDIEV 368


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.313    0.129    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 32,708,623
Number of extensions: 1335093
Number of successful extensions: 3342
Number of sequences better than 1.0e-05: 21
Number of HSP's gapped: 3304
Number of HSP's successfully gapped: 21
Length of query: 491
Length of database: 38,378,431
Length adjustment: 110
Effective length of query: 381
Effective length of database: 25,691,691
Effective search space: 9788534271
Effective search space used: 9788534271
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 118 (50.1 bits)