BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0417.0011.p (518 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 367 e-101 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 159 1e-38 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 105 1e-22 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 99 2e-20 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 97 4e-20 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 367 bits (942), Expect = e-101, Method: Compositional matrix adjust. Identities = 196/527 (37%), Positives = 307/527 (58%), Gaps = 15/527 (2%) Query: 1 VFKVLLVDDEVFVRKGLLELIPWESLKLSIVGEANNGAEALDMITQLEPDLVITDIRMPI 60 ++KVLL DDE FVR GL LI WE + EA+NG +A ++ +++PDLVITDIRMP+ Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 LDGLDLIRSVNEHAGLDLIFIIISGFHDFKYAQQALRYGVHDYILKPIDEEEMTAALRKL 120 DGL LI+ VNE + FIIISG++DF YAQ+A+R+G D++LKPID++E+ AAL KL Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 121 SYAMGRKRIAALTNEDLTTSAIMEALVQENLQAEDAEPYAAALGLEGKSGFLYAVTEIHA 180 + + +++ E + I + EN + + +AA L + + + Y + E++ Sbjct: 121 AATLDQEKATNSDQEKVLLDQIFIHSLGENKKENEVRRWAAKLNINNRHFYYYLLLEVNN 180 Query: 181 GRRDKPATVKQFQEALHSL-----------EEGGAGIPVFEQQPGTFGMLLCTDGITGGH 229 DK +Q++E + + EE A ++EQ +G+L+ ++ + + Sbjct: 181 LSLDKGFINEQYKEPIRKVIRETVARQAATEEYTA---IYEQLDHAYGLLITSEHLKKFN 237 Query: 230 GGLMXXXXXXXXXXXXXXDTGLSLYAGDPVDTLDHVHRSYAEANEAARHKYAENTGVIMY 289 G + + L++Y G D L + +SY AN +KY N + Sbjct: 238 GQIEPLAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANSLRNYKYIFNEKNVFI 297 Query: 290 SDIKDKPLYVFD-MSPVLANQLIMQLEEGNKKDYLETVNRMFRLFHEQRFTPQAVAGSLS 348 + + +D ++ L L+ Q+EE N + ++++F F ++F P AV S++ Sbjct: 298 HEQTESVDTTYDELNNHLFVTLMEQMEENNSDRIVNIIDKIFSEFQTKKFVPSAVKTSVN 357 Query: 349 RCMTGIIGVMKEMDGNDEEILRLKELAERGHGPWNLQMLQEHFLRAIQEAAEYIARLRKE 408 RC+ ++ ++ M+G+ +I+ + + L++ F + + EAA I LRKE Sbjct: 358 RCVHKVMQTVQAMEGDTGKIISAQAMTNWESYNLTFDQLKQVFTKFVLEAAVIIQELRKE 417 Query: 409 YCLGGIKLVKRYIDTRYRENISLKSIAAEFYMNAVYLGRLFRKTYGVYFNDYLLELRIQE 468 I VK YI+ Y ENISLKSIA+ FYMN VY+G+LF+KT+GVYF +YLL+LR+ E Sbjct: 418 NMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNE 477 Query: 469 AKKLLRQSDLRMYEIAGRVGFQNADYFVTQFEKLEQITPSEYRNMLM 515 AKKLLRQ+D+R+YE+A RVGF + DYFVTQFEK+ ++TP+EYRN L+ Sbjct: 478 AKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYRNKLL 524 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 159 bits (401), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 141/521 (27%), Positives = 235/521 (45%), Gaps = 36/521 (6%) Query: 1 VFKVLLVDDEVFVRKGLLELIPWESLKLSIVGEANNGAEALDMITQLEPDLVITDIRMPI 60 ++ V++VDDE VR+GL LI WE ++ A NG E QL PDL+I DIRMP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 61 LDGLDLIRSVNEHAGLDLIFIIISGFHDFKYAQQALRYGVHDYILKPIDEEEMTAALRKL 120 +DGL LI S+ + FII+SG DF YA++AL DY+LKP+DE+E+ +L+K+ Sbjct: 61 VDGLSLIESIRAEDSA-IHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKV 119 Query: 121 SYAMGRKRIAALTNEDLTTSAIMEALVQENLQAEDAEPYAAALGLEGKSGFLYAVTEIHA 180 + R E + + E ++ E L+ + + + + F ++ Sbjct: 120 YGRITRHHQVHELVERVQEKQV-EMVLTELLEGTP----LSEIPIGKEHNFFATDYQVAL 174 Query: 181 GRRDKPATVKQFQEALHSLEEGGAGIPVFEQQPGTFGMLLCTDGITGGHGGLMXXXXXXX 240 + KQ + + EEG IP E + +++C + G Sbjct: 175 VENRQDRLTKQLKRLIEEQEEGYV-IPFPE-----YIVIVCKNRFLQKRG----KDHRYH 224 Query: 241 XXXXXXXDTGLSLYAGDPVDTLDHVHRSYAEANEAARHKYAENTGVIMYSDI---KDKPL 297 + L AG V L ++ SY A K+ G + +D + KP Sbjct: 225 LFAKWLEEEELHACAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQLVDRSKPE 284 Query: 298 YVFDMSPVLANQLIMQLEEGNKKDYL----ETVNRMFRLFHEQRFTPQAVAGSLSRCMTG 353 A++L ++ GN + + E N + E++ A+ S + Sbjct: 285 APEFSLESYADRLYYSIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVALFQLYSNILHQ 344 Query: 354 IIGVMKEMDGNDEE-ILRLKELAERGHGPWNLQMLQEHFLRAIQ--EAAEYIARLRKEYC 410 ++ M+G E ++ ++ + H P + L + I + + LRK Sbjct: 345 LVRSHPNMEGVLEPLVMNAGDIYQFEHLPGIMAFLTKQLKYVIDCMDNGQPDLLLRKMIA 404 Query: 411 LGGIKLVKRYIDTRYRENISLKSIAAEFYMNAVYLGRLFRKTYGVYFNDYLLELRIQEAK 470 L I Y +N+ L+++A+ F N YLG+LF+ G YFN YL ++RI+ K Sbjct: 405 L---------IHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGK 455 Query: 471 KLLRQSDLRMYEIAGRVGFQNADYFVTQFEKLEQITPSEYR 511 +LL Q ++YE+A ++G+ N DYF +F+K ++PS +R Sbjct: 456 RLL-QKGYKVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFR 495 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 105 bits (263), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 54/140 (38%), Positives = 88/140 (62%), Gaps = 7/140 (5%) Query: 4 VLLVDDEVFVRKGLLELIPWESLKLSIVGEANNGAEALDMITQLEPDLVITDIRMPILDG 63 VL+VDDE +R+G++ WE IVGEA NG +AL++I++ EP +V+TDI MP++DG Sbjct: 4 VLIVDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPVMDG 63 Query: 64 LDLIRSVNEHAGLDLIFIIISGFHDFKYAQQALRYGVHDYILKP-IDEEEMTAALRKLSY 122 +DL++ V ++ I++S F +F+Y + GV DYILKP ++E+++ L ++ Sbjct: 64 IDLVKRVKRDFP-EVEIIVLSSFEEFEYVRSTFHSGVADYILKPRLNEKDLLKTLSEV-- 120 Query: 123 AMGRKRIAALTNEDLTTSAI 142 R +I AL D + A+ Sbjct: 121 ---RGKIPALAKVDSPSRAV 137 Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 33/92 (35%), Positives = 54/92 (58%) Query: 420 YIDTRYRENISLKSIAAEFYMNAVYLGRLFRKTYGVYFNDYLLELRIQEAKKLLRQSDLR 479 YI+ + E +SL +A F+ N YL FR+ + F++YL ++RI++AK+ L+ S + Sbjct: 408 YIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYLNKVRIRKAKEWLKSSTIP 467 Query: 480 MYEIAGRVGFQNADYFVTQFEKLEQITPSEYR 511 + EI VG+ + YF F+K + PS YR Sbjct: 468 ISEIYALVGYSDHSYFCKVFKKRTGMPPSRYR 499 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 99.0 bits (245), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 68/223 (30%), Positives = 124/223 (55%), Gaps = 17/223 (7%) Query: 1 VFKVLLVDDEVFVRKGLLELIPWESLKLSIVGEANNGAEALDMITQLEPDLVITDIRMPI 60 ++KV+++DDE V +GL ++I W++L VGEA NG LD++ + P +V+TDI MPI Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 LDGLDLIRSVNEHAGLDLIFIIISGFHDFKYAQQALRYGVHDYILKPIDEEEMTAALRKL 120 + GLD+I+ + E G D +I+SG+ +F++A++A++ + DY+ KP + + L+++ Sbjct: 61 MYGLDMIQILRED-GFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRV 119 Query: 121 SYAMGRKR-----IAALTN-----EDLTTSAIMEALVQENLQ-AEDAEPYAAALGLEGKS 169 + K+ + LTN E L + M++L+ L+ E E + A + + K Sbjct: 120 INKLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNGEIPEEFLAKIT-KWKD 178 Query: 170 GFLYAVTEIHAGRRD---KPATVKQFQEALHSL-EEGGAGIPV 208 A + + G ++ KPA F+ ++H + E G P+ Sbjct: 179 QQHIACSLTYDGPQNKELKPADWYLFRYSVHKMIREVLNGYPI 221 Score = 79.3 bits (194), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 37/96 (38%), Positives = 63/96 (65%) Query: 414 IKLVKRYIDTRYRENISLKSIAAEFYMNAVYLGRLFRKTYGVYFNDYLLELRIQEAKKLL 473 I+ V YI+ ENI+L+ IA E Y++ YLG++F+K G F +Y+ LR+++AKK++ Sbjct: 426 IEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRMEKAKKMI 485 Query: 474 RQSDLRMYEIAGRVGFQNADYFVTQFEKLEQITPSE 509 ++ + +YE++ +VG+ N YF T F+K TP + Sbjct: 486 QEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTPRD 521 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 97.4 bits (241), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 1/117 (0%) Query: 1 VFKVLLVDDEVFVRKGLLELIPWESLKLSIVGEANNGAEALDMITQLEPDLVITDIRMPI 60 + +V+LVDDE + +GL LI W L IV A NG EAL++ + DL+ITDI+MP Sbjct: 1 MIRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPE 60 Query: 61 LDGLDLIRSVNEHAGLDLIFIIISGFHDFKYAQQALRYGVHDYILKPIDEEEMTAAL 117 GL+LI ++NE + I++SGF +F + +Q L G+ +Y+LKPI+E+E+ + L Sbjct: 61 KTGLELIAALNEREK-TIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTL 116 Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 41/100 (41%), Positives = 66/100 (66%) Query: 414 IKLVKRYIDTRYRENISLKSIAAEFYMNAVYLGRLFRKTYGVYFNDYLLELRIQEAKKLL 473 I+ V ++I + +++SLK++ F++N +YLG+LF++ G F YL +LRI AKKLL Sbjct: 405 IQTVLQHIHQHFSQDLSLKTLGHSFHINPIYLGQLFQREVGCSFTKYLNQLRIDRAKKLL 464 Query: 474 RQSDLRMYEIAGRVGFQNADYFVTQFEKLEQITPSEYRNM 513 S R +I +VG+ +A YF QF+K E +TP+E+R + Sbjct: 465 LNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWRKV 504 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 36,967,015 Number of extensions: 1467285 Number of successful extensions: 5342 Number of sequences better than 1.0e-05: 346 Number of HSP's gapped: 5329 Number of HSP's successfully gapped: 356 Length of query: 518 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 407 Effective length of database: 25,576,357 Effective search space: 10409577299 Effective search space used: 10409577299 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)