BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0416.0003.p (155 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0578 [KE] COG1167 Transcriptional regulators containing a DNA-... 72 4e-13 FN1462 [KE] COG1167 Transcriptional regulators containing a DNA-... 71 6e-13 YPO2845 [KE] COG1167 Transcriptional regulators containing a DNA... 70 1e-12 BS_ydeL [KE] COG1167 Transcriptional regulators containing a DNA... 67 1e-11 BS_yhdI [KE] COG1167 Transcriptional regulators containing a DNA... 66 2e-11 >BH0578 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 469 Score = 71.6 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 5/152 (3%) Query: 4 LLGIRISAIVGPAEAIAQLANVQAFTYRHLPFLEQMALAHFIEHGYFMRHMRRAKNIYRR 63 L IR+S +V P E + A + L Q AL FI+ G F RH+RR K +Y+ Sbjct: 317 LPSIRVSYMVLPGELVPLYQQKLANYNQAASQLIQRALYTFIKDGDFQRHIRRMKKVYQS 376 Query: 64 RHEVMQKAITASGLGNKFTLRGIETGLHVLLEADESFDEETMTFRALQGGVRVHQLHSYC 123 +H + K++ + LG++ T+ G ++GLHVLL D E + +A+ GV+V+ ++ Sbjct: 377 KHHTLLKSVK-TYLGDRVTVIGEKSGLHVLLNVPGREDHELIE-KAMACGVKVYSTKTFW 434 Query: 124 LESRRKG---WVLGFAKVDERFIEEGMYRLAE 152 + + +LGF K+ E I++G+ RL + Sbjct: 435 YNPKNQCSSFIMLGFGKLSEEAIKKGIRRLQQ 466 >FN1462 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 469 Score = 71.2 bits (173), Expect = 6e-13, Method: Composition-based stats. Identities = 37/147 (25%), Positives = 80/147 (54%), Gaps = 6/147 (4%) Query: 6 GIRISAIVGPAEAIAQLANVQAFTYRHLPFLEQMALAHFIEHGYFMRHMRRAKNIYRRRH 65 IR+S +V P E + + +P L Q L FI+ GYF++H+ + + +Y+++ Sbjct: 310 AIRVSYLVLPKELLNIYQKKLPYFICPVPTLNQKILYRFIKDGYFVKHINKMRTLYKKKR 369 Query: 66 EVMQKAI---TASGLGNKFTLRGIETGLHVLLEADESFDEETMTFRALQGGVRVHQLHSY 122 E + I ++ LG + +++G + GLH++++ ++ +E+ L+ ++++ L Y Sbjct: 370 EYLVNTIKMYSSEILGKEISIQGADAGLHLVIKLNKKINEKMFLKECLENSLQLYSLEEY 429 Query: 123 CLE---SRRKGWVLGFAKVDERFIEEG 146 LE + ++LG+A + + I+EG Sbjct: 430 YLEKIYNETSSFLLGYANLANKEIDEG 456 >YPO2845 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 501 Score = 69.7 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 47/140 (33%), Positives = 68/140 (48%), Gaps = 2/140 (1%) Query: 6 GIRISAIVGPAEAIAQLANVQAFTYRHLPFLEQMALAHFIEHGYFMRHMRRAKNIYRRRH 65 G+RIS +V P Q + YR + Q+ LA FI G++ H+RR + IY +R Sbjct: 343 GMRISYMVLPRPLAQQFKVAHSELYRGGNGMMQLTLAEFIREGHYASHIRRMRLIYGKRR 402 Query: 66 EVMQKAITASGLGNKFTLRGIETGLHVLLEADESFDEETMTFRALQGGVRVHQLHSYCLE 125 + I LG F GLH++L ES D+ ++ Q GV V L Y L+ Sbjct: 403 AALVGMIKQQ-LGGSFLAEYGNAGLHLILALPESIDDVALSAELEQKGVLVRALSGYYLK 461 Query: 126 S-RRKGWVLGFAKVDERFIE 144 S R+G +LG+ V E +E Sbjct: 462 SPPRRGLLLGYGCVPEEAME 481 >BS_ydeL [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 463 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 42/148 (28%), Positives = 80/148 (54%), Gaps = 2/148 (1%) Query: 4 LLGIRISAIVGPAEAIAQLANVQAFTYRHLPFLEQMALAHFIEHGYFMRHMRRAKNIYRR 63 L +RIS ++ P+ + + + + + + Q+ LA FI++G + +H+ R + +YR+ Sbjct: 311 LPSLRISYMILPSPLLKKGHEITSLYKQTVSCHSQLTLAEFIKNGEWQKHINRMRKLYRK 370 Query: 64 RHEVMQKAITASGLGNKFTLRGIETGLHVLLEADESFDEETMTFRALQGGVRVHQLH-SY 122 + ++ +A+ LG +RG +GL +LL+ F E+ + +A + GV+++ + SY Sbjct: 371 KRAIVLEAVQRE-LGEHVRIRGENSGLRILLDVYLPFGEKELIEKAKKHGVKIYPVSLSY 429 Query: 123 CLESRRKGWVLGFAKVDERFIEEGMYRL 150 K LGFA V E I EG+ +L Sbjct: 430 QHHPPTKTVSLGFAGVSESDIREGIKKL 457 >BS_yhdI [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 469 Score = 65.9 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 44/148 (29%), Positives = 77/148 (52%), Gaps = 2/148 (1%) Query: 4 LLGIRISAIVGPAEAIAQLANVQAFTYRHLPFLEQMALAHFIEHGYFMRHMRRAKNIYRR 63 L +R+S ++ P E + + N + + Q+ALA FIE G + +H+ R +++YR+ Sbjct: 312 LPSLRLSFMIVPPELMEPIQNNVQLMKQTVSAHSQLALADFIETGEWQKHINRMRSLYRK 371 Query: 64 RHEVMQKAITASGLGNKFTLRGIETGLHVLLEADESFDEETMTFRALQGGVRVHQLH-SY 122 +H V+ +AI S LGN + G +GLH+LL EE A GV ++ + SY Sbjct: 372 KHAVLLEAIR-SELGNTVEILGKNSGLHILLRLLFPASEEEAIQAAADHGVTLYPVSPSY 430 Query: 123 CLESRRKGWVLGFAKVDERFIEEGMYRL 150 ++ ++G+ + E I G+ +L Sbjct: 431 IEQTPFTSVLIGYGGLSEEDIRLGIQKL 458 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.327 0.140 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 11,291,011 Number of extensions: 380083 Number of successful extensions: 897 Number of sequences better than 1.0e-05: 15 Number of HSP's gapped: 897 Number of HSP's successfully gapped: 15 Length of query: 155 Length of database: 38,378,431 Length adjustment: 97 Effective length of query: 58 Effective length of database: 27,191,033 Effective search space: 1577079914 Effective search space used: 1577079914 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 111 (47.4 bits)