BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0416.0001.p
         (200 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

FN0217 [T] COG0664 cAMP-binding proteins - catabolite gene activ...    61   1e-09
PM1157 [T] COG0664 cAMP-binding proteins - catabolite gene activ...    49   7e-06

>FN0217 [T] COG0664 cAMP-binding proteins - catabolite gene activator and
           regulatory subunit of cAMP-dependent protein kinases
          Length = 217

 Score = 60.8 bits (146), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 51/194 (26%), Positives = 85/194 (43%), Gaps = 18/194 (9%)

Query: 6   RTVSPSTSLSIREGHIFQHA------VFVLCGTVRIFKGNEQGREITLY-----RVQDGQ 54
           + +  S  LS++E  IF ++      +F+  G +R F  +   RE+ LY      V+  +
Sbjct: 27  KIILSSRVLSLKENSIFFNSHELDGLLFLKSGKLRFFLSSLDARELPLYYLNNMEVEFFE 86

Query: 55  NCVLMMASILGDTPYXXXXXXXXXXXXXXXPIPLFKKWIEICQPLKQFIFGQMVERITSV 114
           N      S + D  +                + LF+    I +   +F+     E+ +  
Sbjct: 87  NFTDKTISTILDIAFIVEKNSEILLIPYSV-LNLFRNKYSIME---KFLHNLTREKFSKS 142

Query: 115 MTLLDNVAFRPINYRIAQFLLGRTDENHATLRITHEQAAIELGTAREVVSRALKVLTDNR 174
           +  L N+   P+  R+  FL G    N   + +THE+ A  LG++REV+SR LKVL    
Sbjct: 143 LLSLQNILLIPLKDRLLNFLYGL---NRTEISLTHEEIAKNLGSSREVISRNLKVLEKEN 199

Query: 175 LISQGRGYIEVLDR 188
            +   R  I +LDR
Sbjct: 200 FLKINRKKIIILDR 213


>PM1157 [T] COG0664 cAMP-binding proteins - catabolite gene activator and
           regulatory subunit of cAMP-dependent protein kinases
          Length = 209

 Score = 48.5 bits (114), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 44/190 (23%), Positives = 76/190 (40%), Gaps = 23/190 (12%)

Query: 2   QCEIRTVSPSTSLSIREGHIFQHAVFVLCGTVRIFKGNEQGREITLYRVQDGQNCVLMMA 61
            C I    PS S  I  G   +   +++ G+V +   +E G+E+ L  +  G        
Sbjct: 17  HCHIHKY-PSKSTLIHAGEKAETLYYLIKGSVAVLVKDEDGKEMILTYLSQG-------- 67

Query: 62  SILGDTPYXXXXXXXXXXXXXXXPIPL-------FKKWIEICQPLKQFIFGQMVERITSV 114
              G+                  P  +       F++ I++   +   +  Q+  R+ + 
Sbjct: 68  DFFGEAGLFEEGQLRSAWIKAKSPCEIAEISYKKFRQLIQVNPDILMHLSAQLARRLQNT 127

Query: 115 MTLLDNVAFRPINYRIAQFLL-------GRTDENHATLRITHEQAAIELGTAREVVSRAL 167
              + N+AF  +  RIAQ LL         T  +   ++IT ++    +G +RE V R L
Sbjct: 128 SRQVSNLAFLDVTGRIAQTLLNLAKMPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIL 187

Query: 168 KVLTDNRLIS 177
           K+L D  LIS
Sbjct: 188 KMLEDQHLIS 197


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.326    0.140    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 11,866,175
Number of extensions: 421207
Number of successful extensions: 1216
Number of sequences better than 1.0e-05: 2
Number of HSP's gapped: 1227
Number of HSP's successfully gapped: 2
Length of query: 200
Length of database: 38,378,431
Length adjustment: 101
Effective length of query: 99
Effective length of database: 26,729,697
Effective search space: 2646240003
Effective search space used: 2646240003
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 113 (48.1 bits)