BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0412.0019.p (203 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0431 [S] COG1284 Uncharacterized conserved protein 88 9e-18 BH1678 [S] COG1284 Uncharacterized conserved protein 86 3e-17 BH2916 [S] COG1284 Uncharacterized conserved protein 77 1e-14 CAC1325 [S] COG1284 Uncharacterized conserved protein 76 4e-14 lin2023 [S] COG1284 Uncharacterized conserved protein 72 5e-13 >CAC0431 [S] COG1284 Uncharacterized conserved protein Length = 291 Score = 87.8 bits (216), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 60/182 (32%), Positives = 92/182 (50%), Gaps = 3/182 (1%) Query: 5 NIMISFIGCFIMGLGVNLGYVPVHLFSTGFPGIGVLALYVLDWNTGIVVFALNVPLFLLA 64 NI + IGCF +G+NL + HL S G GI ++ Y+ GI +N+PLFLL+ Sbjct: 16 NIFYTVIGCFTSSIGINLFLIHAHLLSGGVSGISLILQYLFKIPAGISYLIMNLPLFLLS 75 Query: 65 WKSIGRSFVIQTIIVAGVLSVFLDLLYPIRNW--VHPPLWLGIVVGGAFMGLGAGIVFRQ 122 +K IG+ F TI+ SV +L P +N + P+ L V GG GLG GIV Sbjct: 76 YKVIGKKFTAMTILGTLTFSVAFNLTAPFKNLLTIKDPILL-CVYGGVLNGLGMGIVLSN 134 Query: 123 GLTSGGVGLLARLIQLHYPKLKMGTIHIGFDFFVLILGAVVMDITTAFYTFLASIIMGRT 182 + GG+ ++A I+ + + T + + ++ LGA+ + +A YT + I Sbjct: 135 YGSLGGLDIVAAAIKKKHENFQFSTTSLIINILIITLGAIFFGLPSALYTLFSIYISYSV 194 Query: 183 MD 184 MD Sbjct: 195 MD 196 >BH1678 [S] COG1284 Uncharacterized conserved protein Length = 290 Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 62/196 (31%), Positives = 96/196 (48%), Gaps = 10/196 (5%) Query: 1 LKLNNIMISFIGCFIMGLGVNLGYVPVHLFSTGFPGIGVLALYVLDWNTGIVVFALNVPL 60 LK NI+ +G I G+ + +L GF GI ++ ++ N + LN+P+ Sbjct: 5 LKWKNIVFILLGSAIFSFGLVYFNMENNLAEGGFTGITLILYFMFQINPAVTNLVLNIPI 64 Query: 61 FLLAWKSIGRSFVIQTIIVAGVLSVFLDLLYPIRNW------VHPPLWLGIVVGGAFMGL 114 L+ WK +GR +I TII +SVFL++ + W +H + L + G F+G Sbjct: 65 LLIGWKILGRVTLIYTIIGTVSVSVFLEMF---QRWKFMDIPLHDDMTLAALFAGVFVGT 121 Query: 115 GAGIVFRQGLTSGGVGLLARLIQLHYPKLKMGTIHIGFDFFVLILGAVVMDITTAFYTFL 174 G GIVFR G T+GGV ++A+L Y MG FD V+ + ++ A YT L Sbjct: 122 GLGIVFRFGGTTGGVDIIAKL-GFRYLGWSMGKTMFMFDAVVIASSLIYLNYREAMYTLL 180 Query: 175 ASIIMGRTMDFTKSVP 190 A I + +DF + Sbjct: 181 AVFIAAKVIDFIQQTA 196 >BH2916 [S] COG1284 Uncharacterized conserved protein Length = 293 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 48/188 (25%), Positives = 99/188 (52%), Gaps = 13/188 (6%) Query: 2 KLNNIMISFIGCFIMGLGVNLGYVPVHLFSTGFPGIGVLALYVLDWNTGIVVFALNVPLF 61 +L I++ IG + +N +P +F++GF G+ + +L +TGI++ LN+P+ Sbjct: 24 ELKKIVVVVIGAVFLAASLNFFLIPADVFASGFTGVAQILATLLPLSTGILLLLLNIPVA 83 Query: 62 LLAWKSIGRSFVIQTIIVAGVLSVFLDLLYPIRNWVHPPLWLGIVVGGAFMGLGAGIVFR 121 ++ W +G++F + + + + ++FL+ ++P++ + P + L V GG +GAGI + Sbjct: 84 IIGWLKLGKAFTVYSFLSVALTTLFLE-VFPVQAF-SPDILLNAVFGGVVAAIGAGITLK 141 Query: 122 QGLTSGGVGLLARLIQLHYPKLKMGTIHIGFDFFVL-----ILGAVVMDITTAFYTFLAS 176 G +SGG+ ++A L+ ++ +G FF+L + + D A YT + Sbjct: 142 VGASSGGLDIIALLLS------RVSDRPVGIYFFLLNGLIVVASGFLFDAEKALYTLVTL 195 Query: 177 IIMGRTMD 184 + R +D Sbjct: 196 YVTSRIID 203 >CAC1325 [S] COG1284 Uncharacterized conserved protein Length = 285 Score = 75.9 bits (185), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 51/184 (27%), Positives = 96/184 (52%), Gaps = 2/184 (1%) Query: 3 LNNIMISFIGCFIMGLGVNLGYVPVHLFSTGFPGIGVLALYVLDWNTGIVVFALNVPLFL 62 +N I++ +G I +G+ + +P ++ G GI ++A + ++ GI +F LN+P + Sbjct: 12 INKILLMVLGSVIASVGLEIFLIPNNIIDGGITGISIIANHFINLPLGIFIFLLNLPFLI 71 Query: 63 LAWKSIGRSFVIQTIIVAGVLSVFLDLLYPIRNWVHPPLWLGIVVGGAFMGLGAGIVFRQ 122 + +K IG++F T+ LS+ + +L+PI H L L + GG +G G G++ R Sbjct: 72 VGYKQIGKTFAFSTLFSVICLSIGVSVLHPIPGITHDIL-LATIFGGIILGAGVGLIIRN 130 Query: 123 GLTSGGVGLLARLIQLHYPKLKMGTIHIGFDFFVLILGAVVMDITTAFYTFLASIIMGRT 182 G + G ++A ++ +G I + F+ F+L +V A Y+ +A I +T Sbjct: 131 GGSLDGTEIVAIILDKRIG-FSIGEIVMFFNLFILGASGIVFGWDRAMYSLIAYFIAFKT 189 Query: 183 MDFT 186 +D T Sbjct: 190 IDIT 193 >lin2023 [S] COG1284 Uncharacterized conserved protein Length = 288 Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 56/190 (29%), Positives = 88/190 (46%), Gaps = 3/190 (1%) Query: 1 LKLNNIMISFIGCFIMGLGVNLGYVPVHLFSTGFPGIGVLALYVLDWNTGIVVFALNVPL 60 L+ NI +G I G+ + +L G G+ + L+ + LN+PL Sbjct: 5 LRTKNICFIMLGTAIYAFGLVNFNIANNLGEGGLAGVTLFLLHFFQIDPAYSNLVLNIPL 64 Query: 61 FLLAWKSIGRSFVIQTIIVAGVLSVFLDLLY--PIRNWVHPPLWLGIVVGGAFMGLGAGI 118 F++ W+ +G +I T I LS+FL + P +H L L + G F G+G G+ Sbjct: 65 FIIGWRVLGSRSLIYTGIGTVSLSLFLWIFQRIPYTLDLHSDLLLVALFAGGFSGIGLGL 124 Query: 119 VFRQGLTSGGVGLLARLIQLHYPKLKMGTIHIGFDFFVLILGAVVMDITTAFYTFLASII 178 VFR G T+GG ++A+L+ H + MG D VL +D+ YT +A I Sbjct: 125 VFRYGGTTGGSDIIAKLLN-HTKGISMGRTLFAIDAIVLAASLSYLDVRQVMYTLVAVFI 183 Query: 179 MGRTMDFTKS 188 R +DF + Sbjct: 184 GSRVIDFVQE 193 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.332 0.149 0.471 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,495,808 Number of extensions: 699118 Number of successful extensions: 2196 Number of sequences better than 1.0e-05: 35 Number of HSP's gapped: 2142 Number of HSP's successfully gapped: 35 Length of query: 203 Length of database: 38,378,431 Length adjustment: 101 Effective length of query: 102 Effective length of database: 26,729,697 Effective search space: 2726429094 Effective search space used: 2726429094 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 113 (48.1 bits)