BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0412.0006.p (313 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0622 [CR] COG0604 NADPH:quinone reductase and related Zn-depe... 81 2e-15 mll2594 [CR] COG0604 NADPH:quinone reductase and related Zn-depe... 79 9e-15 DR1061 [CR] COG0604 NADPH:quinone reductase and related Zn-depen... 74 3e-13 Cgl2908 [CR] COG0604 NADPH:quinone reductase and related Zn-depe... 71 2e-12 CC0096 [CR] COG0604 NADPH:quinone reductase and related Zn-depen... 67 3e-11 >lin0622 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases Length = 346 Score = 80.9 bits (198), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 14/304 (4%), Positives = 40/304 (13%), Gaps = 29/304 (9%) Query: 1 MIRAIVSDPNSPSNLTIQEVAPPQAQPWESIVEVHAISLN-------RGEIKDAVNQRTS 53 M + + + Q E+ V R Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 54 SRLGWDFAGVVAKSAEMGNGPKAGARVVG---LLPMGAWGERIAVPSSALAEIPDNVRFA 110 ++ + + A V A+ + E + Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 111 EAATLPVAGLTALNAXXXXXXXXX-XXVLITGSTGGVGLFAHQLAKLSGAFNVGIASTEE 169 + + LA+ A + Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSN 180 Query: 170 KAELVLEAGANEVLVGASVPSHVSQFGPYDLIIDSVGGDTXXXXXXXXXX-XGSCIA-VG 227 + + + + +++ + Sbjct: 181 E-TAFGVMRYLHLADKHDL-PRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGF 238 Query: 228 FSSSPSSTLDMSNFITNGGRTLYGFFLGEELTRHPAASDLAILTNLVSTGCLKPKIAVEA 287 + + + IA Sbjct: 239 GTLTGKYL--NGAKPAGA------------RNTLFSRFTRYSGEQTQKAVAAYVDIARRH 284 Query: 288 PWTE 291 Sbjct: 285 GLDP 288 >mll2594 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases Length = 326 Score = 79.0 bits (193), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 92/317 (29%), Positives = 134/317 (42%), Gaps = 22/317 (6%) Query: 12 PSNLTIQEVAPPQAQPWESIVEVHAISLNRGEI-----KDAVNQRTSSRLGWDFAGVVAK 66 P L I E+ P Q E +V VHA +N E+ + AV + G + AG+V Sbjct: 12 PEVLEIVELPAPVPQAGEVLVRVHAAGINFFEVLMRADRYAVTPQLPMFPGVEVAGIVEA 71 Query: 67 SAEMGNGPKAGARVVGLL-----PMGAWGERIAVPSSALAEIPDNVRFAEAATLPVAGLT 121 E + G RV L P G + E++ + + +PD+V F A L V GLT Sbjct: 72 VGEGVDAAFLGRRVAAPLFASQRPYGGYAEQVTISADLTVPLPDDVSFEAATALMVQGLT 131 Query: 122 ALNAXXXXXXXXXXXVLITGSTGGVGLFAHQLAKLSGAFNV-GIASTEEKAELVLEAGAN 180 AL+ VL+ + GGVG QLAK GA V A K EL L GA+ Sbjct: 132 ALH-LLRQSPPEGRTVLVPAAAGGVGSLLVQLAKAKGAAKVIAAAGGAGKIELALSLGAD 190 Query: 181 EVL--VGASVPSHVSQFG---PYDLIIDSVGGDTXXXXXXXXXXXGSCIAVGFSSSPSST 235 + +G+ P+ V D+I D+VGG G + F++ Sbjct: 191 AAVDYIGSDWPARVRALTGGEGADIIYDTVGGALTALSLQALAPGGELV---FAALGRYG 247 Query: 236 LDMSNFITNGGR--TLYGFFLGEELTRHPAASDLAILTNLVSTGCLKPKIAVEAPWTEIS 293 L+ S+ GR +L GF L L+ + L+ L L ++G L+ I P + Sbjct: 248 LEPSDLEAMIGRNQSLRGFALLPLLSPQVLRASLSELFQLAASGRLRVAIGGRFPLGQAG 307 Query: 294 SVAQQLLDRNISGKAVL 310 + L +R +GK VL Sbjct: 308 EAHRLLDERRSTGKVVL 324 >DR1061 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases Length = 346 Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 0/323 (0%), Positives = 0/323 (0%), Gaps = 21/323 (6%) Query: 5 IVSDPNSPSNLTIQEVAPPQAQPWESIVEVHAISLNRGEIKDAVNQR-TSSRL----GWD 59 V + + + + + + + K+ S + D Sbjct: 68 YVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD 127 Query: 60 FAGVVAKSAEMGNGPKAGARVVGLLPMGAWGERIAVPSSALAEIPDNVRFAEAATLPVAG 119 V K G P + + + + T Sbjct: 128 LYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVM 187 Query: 120 LTALNAXXXXXXXXXXX-VLITGSTGGVGLFAHQLAKLSGAFNVGIASTEEKAELVLEAG 178 A + + ++++ G + + Sbjct: 188 RYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLN 247 Query: 179 ANEVLVGASVPSHVSQFGP------YDLIIDSVGGDTXXXXXXXXXXXGSCIAVGFSSSP 232 GA + +S+ Sbjct: 248 GA-KPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTL 306 Query: 233 SSTLD----MSNFITNGGRTLYGFFLGEELTRHPAASDLAILTNLVSTGCLKPKIAVEAP 288 +N + E Sbjct: 307 LGATTMDQLKTNIESLHLELSEDVLAEIEAV--HQVYT-- 362 Query: 289 WTEISSVAQQLLDRNISGKAVLH 311 Sbjct: 363 385 >Cgl2908 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases Length = 346 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 25/322 (7%), Positives = 51/322 (15%), Gaps = 31/322 (9%) Query: 1 MIRAIVSDP-NSPSNLTIQEVAPPQAQPWESIVEVHAISLNRGEIKDAVNQRTSSR---- 55 M + S L + + + ++ +G V + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 56 -LGWDFAGVVAKSAEMGNGPKAGARVVGLLP--MGAWGERIAVPSSALAEIPDNVRFAEA 112 G V A+ G+ K P G R + Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 113 ATLPVAGLTALNAXXXXXXXXXXXVLITGSTGGVGLFAHQLAKLSGAFNVGIASTEEKAE 172 L ++ + L L+ + Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALA-EYQRAGKIRYIGVS 179 Query: 173 LVLEAGANEVLVGASVPSHVSQFGP--YDLIIDSVGGDTXXXXXXXXXXXGSCIAVGFSS 230 G L A +++ + Sbjct: 180 NETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLA------------EVSQYEG 227 Query: 231 SPSSTLDMSNFITNGGRTLYGFFLGEELTRHPAASDLAILTNLVSTGCLKPKIAVEAPWT 290 F T A + + + + AV A Sbjct: 228 VELLAYSCLGFGT------LTGKYLNGAKPAGAR--NTLFSRFTRYSGEQTQKAVAAYVD 279 Query: 291 EISSVAQQLLDRNISGKAVLHL 312 ++ Sbjct: 280 IARRHGLDPAQMALAFVRRQPF 301 >CC0096 [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases Length = 346 Score = 67.4 bits (163), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 18/338 (5%), Positives = 46/338 (13%), Gaps = 38/338 (11%) Query: 2 IRAIVS-DPNSPSNLTIQEVAPPQAQPWESIVEVHAISLNRGE---IKDAVNQRTSSRL- 56 ++ + + Q E+ I A R Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 57 -GWDFAGVVAKSAEMGNGPKAGARVVGLLPMGAWGERIAVPSSALAEIPDNVRFAEAATL 115 V + + ++ P AL ++ Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120 Query: 116 PVAGLTALNAXXXXXXXXXXXVLITGST-------GGVGLFAHQLAKLSGAFNVGIASTE 168 L + + A Sbjct: 121 LQTDYLDLYQVHWPQ------RPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIR 174 Query: 169 EKAELVLEAGANEVLVGASVPSHVS-----------QFGP--YDLIIDSVGGDTXXXXXX 215 A + + + L S Sbjct: 175 YIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYS 234 Query: 216 XXXXXGSCIAVGFSSS-PSSTLDMSNFITNGGRTLYGFFLGEELTRHPA--ASDLAILTN 272 + + + + T L Sbjct: 235 CLGFGTLTGKYLNGAKPAGARNTLFSRFTR---YSGEQTQKAVAAYVDIARRHGLDPAQM 291 Query: 273 LVSTGCLKPKIAVEAPWTEISSVAQQLLDRNISGKAVL 310 ++ +P +A + ++ + Sbjct: 292 ALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSED 329 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.314 0.131 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,831,745 Number of extensions: 789982 Number of successful extensions: 1561 Number of sequences better than 1.0e-05: 118 Number of HSP's gapped: 1476 Number of HSP's successfully gapped: 118 Length of query: 313 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 207 Effective length of database: 26,153,027 Effective search space: 5413676589 Effective search space used: 5413676589 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 116 (49.3 bits)