BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0397.0038.p (608 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0550 [R] COG0488 ATPase components of ABC transporters with du... 303 5e-82 SP1114 [R] COG0488 ATPase components of ABC transporters with du... 300 6e-81 FN2102 [R] COG0488 ATPase components of ABC transporters with du... 300 7e-81 BS_ydiF [R] COG0488 ATPase components of ABC transporters with d... 293 6e-79 AGl1953 [R] COG0488 ATPase components of ABC transporters with d... 289 8e-78 >BH0550 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 642 Score = 303 bits (776), Expect = 5e-82, Method: Compositional matrix adjust. Identities = 198/572 (34%), Positives = 312/572 (54%), Gaps = 49/572 (8%) Query: 1 MTLIKVKNIRKEWNGIPLFANVSFEIAEGERALLFGRNGIGKTTLLQGLLGRHPFDEGSV 60 M +++ NI K + + +N+ E+ G+R L GRNG GK+TLL+ + + +D G + Sbjct: 1 MIVLQCVNITKSFGAETILSNIKLEVKTGDRVALVGRNGAGKSTLLKIIADKLSYDSGDL 60 Query: 61 YYGLPPE--EWGVLDQQLELQSDMSALDYVLSGSPELDDLKCKIERLGR------LLQEA 112 + P+ E G L+Q L+SD++ D +LS L ++ ++ ++ LL A Sbjct: 61 ---IIPKGVEIGYLEQHTGLESDLTIWDEMLSVFEPLQQMERRLRKMEEQMANPALLNNA 117 Query: 113 DGGDEALVAEYGEVYERYLQLDGYGWEAKAEKCLSQLMLDAAVWNLPYRQ-----LSGGQ 167 E L+ EY + + GY +EA L+ L + PY + LSGGQ Sbjct: 118 SSY-EKLLEEYDSLQVEFKDRGGYQYEADIRNVLAGLQF----ADFPYHETKIATLSGGQ 172 Query: 168 KTRVQLAALLARQPKLLVLDEPTNHLDEETMAWLEEWVRDYPGTVFYVSHDRTFIERTAT 227 KTR+ L LL +P LL+LDEPTNHLD +T++WLE+++ YPG + VSHDR F+++ T Sbjct: 173 KTRLALGKLLLTKPDLLILDEPTNHLDIDTLSWLEQYLSAYPGAILIVSHDRYFLDKLVT 232 Query: 228 AVLELGPQGCRRYPGAYTKYREQKEIEARTLAVQYRXXXXXXXXXXXSIRRYAEWFQQAH 287 V E+ +Y G Y+ Y ++K A++Y + E+ +Q Sbjct: 233 QVYEISRTKSTKYVGNYSHYLDEK-------ALRYE-------------QELKEFEKQQK 272 Query: 288 RAAGQNDF--RRAKAKKNVSRLHAKEASLERLELNRVERPQAAPQ-LSMKLEGEVFRGDA 344 A DF R R ++ +LER+ +++RP + + S + E G+ Sbjct: 273 EVAKLEDFIQRNIARASTTKRAQSRRKALERM--TKLDRPNSDEKSASFFFDIERQSGND 330 Query: 345 LLDMSGVRYAYGGGAALLENFNLTLRRGDRLAVLGPNGAGKSTLLKLIAGLLAPDRGEIR 404 +L + + ++Y G L +L L RG+ +A++GPNGAGKSTLLKL+ L D+G I Sbjct: 331 VLRVRDLTFSYDGDP-LFSRLDLDLNRGESVALIGPNGAGKSTLLKLLTKKLQADQGTIE 389 Query: 405 RHPRTRVGYFAQELDNLPLSSTILDSLLE-LPGMTQTEARTILGCFMFRREDVFKRIGDL 463 ++GY+ QE NL + +L L + P + + + RT+LG F+F EDV K + DL Sbjct: 390 YGSHVKIGYYDQEQANLHSNKQVLYELWDDYPLLPERDIRTVLGNFLFSGEDVLKVVSDL 449 Query: 464 SLGEKCRVAFLRLYFGRANLLVLDEPTNYLDIDTRERVEEALAAYPGGLVIVSHDRYLHA 523 S GEK R+A +L +ANLL++DEPTN+LD+D++E +E AL YPG L+ VSHDRY Sbjct: 450 SGGEKARLALAKLMMEKANLLIMDEPTNHLDLDSKEVLENALIDYPGTLLFVSHDRYFLN 509 Query: 524 AVANRLLLLERGSRPRLFPGTYEEYAAKERSL 555 +A R++ L+ G +P +F G Y+ Y K++ + Sbjct: 510 RMATRIIELD-GGQPSVFLGDYDYYLEKKQEI 540 >SP1114 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 633 Score = 300 bits (767), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 192/569 (33%), Positives = 297/569 (52%), Gaps = 32/569 (5%) Query: 1 MTLIKVKNIRKEWNGIPLFANVSFEIAEGERALLFGRNGIGKTTLLQGLLGRHPFDEGSV 60 M +++ I + + G LF N++ ++ E +R L G+NG GK+TLL+ L+G G + Sbjct: 1 MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKSTLLKILVGEEEPTSGEI 60 Query: 61 YYGLPPEEWGVLDQQLELQSDMSALDYVLSGSPELDDLKCKIERLGRLLQEADGGD-EAL 119 L Q +S+ + D +L +L + ++ ++ + E G D + L Sbjct: 61 NKK-KDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLRQMELEMGEKSGEDLDKL 119 Query: 120 VAEYGEVYERYLQLDGYGWEAKAEKCLSQLMLDAAVWNLPYRQLSGGQKTRVQLAALLAR 179 +++Y + E + Q G+ +EA L+ D ++W + +LSGGQ TR+ LA +L Sbjct: 120 MSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKIAELSGGQNTRLALAKMLLE 179 Query: 180 QPKLLVLDEPTNHLDEETMAWLEEWVRDYPGTVFYVSHDRTFIERTATAVLELGPQGCRR 239 +P LLVLDEPTNHLD ET+AWLE ++ +Y G + VSHDR F+++ AT L+L R Sbjct: 180 KPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHDRYFLDKVATITLDLTKHSLDR 239 Query: 240 YPGAYTKYREQKEIEARTLAVQYRXXXXXXXXXXXSIRRYAEWFQQAHRAAGQNDF--RR 297 Y G Y+++ E KE + T A Y +Q A DF R Sbjct: 240 YVGNYSRFVELKEQKLVTEAKNYE--------------------KQQKEIAALEDFVNRN 279 Query: 298 AKAKKNVSRLHAKEASLERLELNRVERPQAAPQ-LSMKLEGEVFRGDALLDMSGVRYAYG 356 R ++ LE++E R+++P+A + +M + E G+ +L + Y Sbjct: 280 LVRASTTKRAQSRRKQLEKME--RLDKPEAGKKSANMTFQSEKTSGNVVLTVENAAVGY- 336 Query: 357 GGAALLENFNLTLRRGDRLAVLGPNGAGKSTLLKLIAGLLAPDRGEIRRHPRTRVGYFAQ 416 G L + NL LR+ + +A++GPNG GKST +K I + +GE R VGY+ Q Sbjct: 337 DGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVGYYDQ 396 Query: 417 ELDNLPLSSTILDSLLELPGMT-QTEARTILGCFMFRREDVFKRIGDLSLGEKCRVAFLR 475 L S+T+LD L +T + E R LG F+F +DV K +G LS GEK R+ + Sbjct: 397 TQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKARLLLAK 456 Query: 476 LYFGRANLLVLDEPTNYLDIDTRERVEEALAAYPGGLVIVSHDRYLHAAVANRLL-LLER 534 L N L+LDEPTN+LDID++E +E AL + G L+ VSHDRY VA +L L E Sbjct: 457 LSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVATHVLELSEN 516 Query: 535 GSRPRLFPGTYEEYAAKERSLMLTPDEQS 563 GS L+ G Y+ Y K+ + ++ E++ Sbjct: 517 GS--TLYLGDYDYYVEKKATAEMSQTEEA 543 >FN2102 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 631 Score = 300 bits (767), Expect = 7e-81, Method: Compositional matrix adjust. Identities = 183/568 (32%), Positives = 295/568 (51%), Gaps = 30/568 (5%) Query: 1 MTLIKVKNIRKEWNGIPLFANVSFEIAEGERALLFGRNGIGKTTLLQGLLGRH------P 54 M +++V +I ++G LF +SF + E ++ + G NG GKTTL++ LLG Sbjct: 1 MAILQVNDIYMGFSGETLFKEISFSVDEKDKIGIIGVNGAGKTTLIKLLLGLENSEINPA 60 Query: 55 FDEGSVYYGLPPEEWGVLDQQLELQSDMSALDYVLSGSPELDDLKCKIERLGRLLQEADG 114 +E + G L Q +L + + + +++ L + +++ + LL Sbjct: 61 TNERGTISKKSNLKVGYLAQNTQLNKENTVFNELMTVFNNLLEDYNRMQEINFLLTLDLD 120 Query: 115 GDEALVAEYGEVYERYLQLDGYGWEAKAEKCLSQLMLDAAVWNLPYRQLSGGQKTRVQLA 174 + L+ E GE+ ERY + +GY E K ++ L+ L + +W + LSGGQ +RV LA Sbjct: 121 NFDKLMEELGEISERYERHEGYSIEYKIKQILNGLNIPENLWTMKIGNLSGGQNSRVALA 180 Query: 175 ALLARQPKLLVLDEPTNHLDEETMAWLEEWVRDYPGTVFYVSHDRTFIERTATAVLELGP 234 +L +P LLVLDEPTNHLD ++ WLE+ ++DY ++ +SHD F++ V E+ Sbjct: 181 KILLEEPDLLVLDEPTNHLDLTSIEWLEKILKDYNKSIILISHDVYFLDNVVNRVFEIEG 240 Query: 235 QGCRRYPGAYTKYREQKEIEARTLAVQYRXXXXXXXXXXXSIRRYAEWFQQAHRAAGQND 294 + + Y G YT + QKE Y IRRY Sbjct: 241 KRLKDYKGNYTDFLIQKEAYLSGEVKAYEKEQEKIKKMEEFIRRY--------------- 285 Query: 295 FRRAKAKKNVSRLHAKEASLERLELNRVERPQAAPQ-LSMKLEGEVFRGDALLDMSGVRY 353 +A K +R +E L R+E ++E P Q + +K + + D +LD+ + Sbjct: 286 --KAGVKSKQAR--GREKILNRME--KMENPVVTTQKIKLKFDIKAQSVDLVLDIKNLSK 339 Query: 354 AYGGGAALLENFNLTLRRGDRLAVLGPNGAGKSTLLKLIAGLLAPDRGEIRRHPRTRVGY 413 + L ++ NL + RG+R+ ++G NG GKSTLLK+I L GE + R +GY Sbjct: 340 TFED-KLLFKDLNLKVYRGERIGLIGKNGTGKSTLLKIINNLEKASSGEFKIGERVSIGY 398 Query: 414 FAQELDNLPLSSTILDSLLELPGMTQTEARTILGCFMFRREDVFKRIGDLSLGEKCRVAF 473 + Q L L++ I++ L+ +++ EAR I G F+FR +D++K+I LS GEK RVAF Sbjct: 399 YDQNHQGLGLNNNIIEELMYYFTLSEEEARNICGAFLFREDDIYKKISSLSGGEKARVAF 458 Query: 474 LRLYFGRANLLVLDEPTNYLDIDTRERVEEALAAYPGGLVIVSHDRYLHAAVANRLLLLE 533 ++L + N L+LDEPTN+LDI +RE + +AL YPG +++VSHDR V N++ L Sbjct: 459 MKLMLEKPNFLILDEPTNHLDIYSREILMDALEDYPGTILVVSHDRNFLDTVVNKIYEL- 517 Query: 534 RGSRPRLFPGTYEEYAAKERSLMLTPDE 561 + F G YE Y + ++ + +E Sbjct: 518 KTDGVETFDGDYEAYKQERDNIKVKNEE 545 >BS_ydiF [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 531 Score = 293 bits (750), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 0/559 (0%), Positives = 0/559 (0%), Gaps = 33/559 (5%) Query: 1 MTLIKVKNIRKEWNGIPLFANVSFEIAEGERALLFGRNGIGKTTLLQGLLGRHPFDEGSV 60 M +K I + V++ E +L GI + T L L + Sbjct: 1 MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEATTLITALADKYKQTQTP 60 Query: 61 YYGLPPEE--WGVLDQQLELQSDMSALDYVLSGSPELDDLKCKIERLGRLLQEADGGD-E 117 L + + A + ++ + + + + Sbjct: 61 ---RNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRISELAEQNKIIAYNYP 117 Query: 118 ALVAEYGEVYERYLQLDGYGWEAKAEKCLSQLMLDAAVWNLPYRQLSGGQKTRVQLAALL 177 V Q + + + + Sbjct: 118 QGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKEDLIKLVEFDNKEYLYYK 177 Query: 178 ARQPKLLVLDEPTNHLDEETMAWLEEWVRDYPGTVFYVSHDRTFIERTATAVLELGPQGC 237 A P + + T + E D V ++ + +++ Sbjct: 178 AIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNNGGIVMMQVQKMVKKATLHP 237 Query: 238 RRYPGAYTKYREQKEIEARTLAVQYRXXXXXXXXXXXSIRRYAEWFQQAHRAAGQNDFRR 297 + + + A + Sbjct: 238 KSVRIPGYLVDIVV-------VDPDQT----------QLYGGAP--VNRFISGDFTLDDS 278 Query: 298 AKAKKNVS-RLHAKEASLERLELNRVERPQAAPQLSMKLEGEVFR--GDALLDMSGVRYA 354 K ++ R +L + G V R G A + V Sbjct: 279 TKLSLPLNQRKLVARRALFEMRK--GAVG-NVGVGIADGIGLVAREEGCADDFILTVETG 335 Query: 355 YGGGAALLENFNLTLRRGDRLAVLGPNGAGKSTLLKLIAGLLAPDRGEIRRHPRTRVGYF 414 GG + + + L + + + Sbjct: 336 PIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKFNGK 395 Query: 415 AQELDNLPLSSTILDSLL-ELPGMTQTEARTILGCFMFRREDVFKRIGDLSLGEKCRVAF 473 S ++ + I + ++ + L E Sbjct: 396 IMGTGGFIDISATSKKIIFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEITFSGK 455 Query: 474 LRLYFGRANLLVLDEPTNYLDIDTRERVEEALAAYPGGLVIVSHDRYLHAAVANRLLLLE 533 + L G + + L D +E A ++ D + +L+ Sbjct: 456 IALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPELKLMDE- 514 Query: 534 RGSRPRLFPGTYEEYAAKE 552 Sbjct: 515 533 >AGl1953 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 134 Score = 289 bits (740), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 0/553 (0%), Positives = 0/553 (0%), Gaps = 31/553 (5%) Query: 2 TLIKVKNIRKEWNGIPLFANVSFEIAEGERALLFGRNGIGKTTLLQGLLGRHPFDEGSVY 61 T+ V + + A ++ + L + + Sbjct: 27 TVSGVPMVTAVSYKSFQELPKAKAPAVLQKLAQAVAAEGFSGIQINKALSSIDAHQETSG 86 Query: 62 Y--GLPPEEWGVLDQQLELQSDMSALDYVLSGSPELDDLKCKIERLGRLLQEADGGDE-- 117 Sbjct: 87 SGRIQT--- 143 Query: 118 ALVAEYGEVYERYLQLDGYGWEAKAEKCLSQLMLDAAVWNLPYRQLSGGQKTRVQLAALL 177 Sbjct: 144 203 Query: 178 ARQPKLLVLDEPTNHLDEETMAWLEEWVRDYPGTVFYVSHDRTFIERTATAVLELGPQGC 237 Sbjct: 204 263 Query: 238 RRYPGAYTKYREQKEIEARTLAVQYRXXXXXXXXXXXSIRRYAEWFQQAHRAAGQNDFRR 297 Sbjct: 264 ----------------- 306 Query: 298 AKAKKNVSRLHAKEASLERLELNRVERPQAAPQLSMKLEGEVFRGDALLDMSGVRYAYGG 357 Sbjct: 307 ---- 362 Query: 358 GAALLENFNLTLRRGDRLAVLGPNGAGKSTLLKLIAGLLAPDRGEIRRHPRTRVGYFAQE 417 Sbjct: 363 422 Query: 418 -LDNLPLSSTILDSLLE-LPGMTQTEARTILGCFMFRREDVFKRIGDLSLGEKCRVAFLR 475 Sbjct: 423 482 Query: 476 LYFGRANLLVLDEPTNYLDIDTRERVEEALAAYPGGLVIVSHDRYLHAAVANRLLLLERG 535 Sbjct: 483 542 Query: 536 SRPRLFPGTYEEY 548 Sbjct: 543 - 554 Score = 105 bits (263), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 0/256 (0%), Positives = 0/256 (0%), Gaps = 41/256 (16%) Query: 3 LIKVKNIRKEWNGIPLFANVSFEIAEGERALLFGRNGIGKTTLLQGLLGRHPFDEGSVYY 62 Sbjct: 351 410 Query: 63 GLPPEEWGVLDQQLELQSDMSALDYVLSGSPELDDLKCKIERLGRLLQEADGGDEALVAE 122 Sbjct: 411 ---------------- 454 Query: 123 YGEVYERYLQLDGYGWEAKAEKCLSQLMLDAAVWNLPYRQLSGGQKTRVQLAALLARQPK 182 Sbjct: 455 ------------------------- 489 Query: 183 LLVLDEPTNHLDEETMAWLEEWVRDYPGTVFYVSHDRTFIERTATAVLELGPQGCRRYPG 242 Sbjct: 490 549 Query: 243 AYTKYREQKEIEARTL 258 Sbjct: 550 565 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.138 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 43,283,249 Number of extensions: 1969675 Number of successful extensions: 36065 Number of sequences better than 1.0e-05: 1400 Number of HSP's gapped: 34072 Number of HSP's successfully gapped: 1708 Length of query: 608 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 496 Effective length of database: 25,461,023 Effective search space: 12628667408 Effective search space used: 12628667408 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 119 (50.4 bits)