BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0397.0002.p
         (418 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sll1200 [GEPR] COG0477 Permeases of the major facilitator superf...    53   1e-06
NMA2100 [GEPR] COG0477 Permeases of the major facilitator superf...    50   5e-06
NMB0388 [GEPR] COG0477 Permeases of the major facilitator superf...    50   7e-06

>sll1200 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 391

 Score = 52.8 bits (125), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 41/197 (20%), Positives = 83/197 (42%), Gaps = 9/197 (4%)

Query: 2   KKVWLLGFGFFSISITWSLYNAFVPFFLEKYVHSVALISFMMTIDNYFALFLQPWIGNRS 61
           ++VW +     S+++ W  Y  ++   L+ +  S   +  ++T +    + ++P  G  S
Sbjct: 10  RRVWGIALVQGSVTLMWITYRLYLGDLLKGWGFSPEFVVGLLTFEMVLGVVMEPLFGALS 69

Query: 62  DRTATRFGRRMPYLMIGMPLAAVLTMLIPF-------HSGXXXXXXXXXXXXXXXXXYRS 114
           DR     G R P + +G+ LAA   +LIP        +                   +RS
Sbjct: 70  DRQQQNLGTRFPLISLGVILAAGFFLLIPLVFFLPIANVARFLLPSLAIAWAIAMTLFRS 129

Query: 115 PTVALMPDITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAAGLITLLCL 174
           PT+ L+    P +Q   A G+++ +GG  +      G +L     +  F+   ++ L   
Sbjct: 130 PTMVLIGQCAPTNQLPLAMGVLSLVGGIVATFRQPMGKWLLSLGSLPAFLLGSVVLLGAS 189

Query: 175 FIVSRFIK--EGRDGVN 189
             +SR +   E ++ ++
Sbjct: 190 LFLSRVLPPIEKKEAIS 206


>NMA2100 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 74

 Score = 50.4 bits (119), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 0/175 (0%), Positives = 0/175 (0%), Gaps = 23/175 (13%)

Query: 4   VWLLGFGFFSISITWSLYNAFVPFFLEKYVHSVALISFMMTIDNYFALFLQPWIGNRSDR 63
                                                                       
Sbjct: 21                                                               80

Query: 64  T-ATRFG-RRMPYLMIGMPLAAVLTMLIP----FHSGXXXXXXXXXXXXXXXXXYRSPTV 117
                                                                       
Sbjct: 81                                                               140

Query: 118 ALMP------DITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAA 166
                                                                  
Sbjct: 141 -----------                                             184


>NMB0388 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 451

 Score = 50.1 bits (118), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 42/175 (24%), Positives = 76/175 (43%), Gaps = 23/175 (13%)

Query: 4   VWLLGFGFFSISITWSLYNAFVPFFLEKYVHSVALISFMMTIDNYFALFLQPWIGNRSDR 63
           +W+L FGF  +   ++L ++ +    +        + +   +     + +QP +G+ SDR
Sbjct: 21  IWMLSFGFLGVQTAFTLQSSQMSRIFQTLGADPHNLGWFFILPPLAGMLVQPIVGHYSDR 80

Query: 64  T-ATRFG-RRMPYLMIGMPLAAVLTMLIP----FHSGXXXXXXXXXXXXXXXXXYRSPTV 117
           T   R G RR+PYL+ G  +A ++ +L+P    F  G                   S  +
Sbjct: 81  TWKPRLGGRRLPYLLYGTLIAVIVMILMPNSGSFGFGYASLAALSFGALMIALLDVSSNM 140

Query: 118 ALMP------DITPEHQRTKANGLINFMGGAGSILAFGAGSYLYDSSPVLPFVAA 166
           A+ P      D+  E Q+  A G+ +F+   G+++A            +LPFV A
Sbjct: 141 AMQPFKMMVGDMVNEEQKGYAYGIQSFLANTGAVVA-----------AILPFVFA 184


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.328    0.142    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 26,076,654
Number of extensions: 914211
Number of successful extensions: 3215
Number of sequences better than 1.0e-05: 6
Number of HSP's gapped: 3217
Number of HSP's successfully gapped: 6
Length of query: 418
Length of database: 38,378,431
Length adjustment: 109
Effective length of query: 309
Effective length of database: 25,807,025
Effective search space: 7974370725
Effective search space used: 7974370725
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 117 (49.7 bits)