BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0391.0037.p (339 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_qoxA [C] COG1622 Heme/copper-type cytochrome/quinol oxidases,... 221 9e-58 BH2064 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, ... 195 1e-49 PA1317 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, ... 137 2e-32 AGc230 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, ... 134 2e-31 AGc2304 [GER] COG0697 Permeases of the drug/metabolite transport... 134 2e-31 >BS_qoxA [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 Length = 321 Score = 221 bits (564), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 115/246 (46%), Positives = 160/246 (65%), Gaps = 3/246 (1%) Query: 25 TVLNPKGPSARTLSDTIILSILVMLGVLAVVYILYIFVLVKYRAKK--SNEGYIPEHEEG 82 +VL+PKGP A SD I+LSI ML ++ VV++L+ +LVKYR +K N Y PE G Sbjct: 30 SVLDPKGPVAEQQSDLILLSIGFMLFIVGVVFVLFTIILVKYRDRKGKDNGSYNPEIH-G 88 Query: 83 NKVLETXXXXXXXXXXAFLSVVTVKTTNAVENQAVEYKDQTPLVIYAASSNWKWHFSYPE 142 N LE LSV TV+T ++E KD+ PLV+YA S +WKW FSYPE Sbjct: 89 NTFLEVVWTVIPILIVIALSVPTVQTIYSLEKAPEATKDKEPLVVYATSVDWKWVFSYPE 148 Query: 143 EGIETVNYVNMPVHRAVEFRMYSFGSITSLWIPQLAGQKYAMSDMLTTLHLSADTEGSYM 202 + IETVNY+N+PV R + ++ S S+ SLWIPQL GQKYAM+ ML +L AD G+Y Sbjct: 149 QDIETVNYLNIPVDRPILCKISSADSMASLWIPQLGGQKYAMAGMLMDQYLQADKVGTYE 208 Query: 203 GRNANFSGKGFAHMEFEALVMSSKDYDDWVKEVKETAPKLTEKEFKGLLATDYLGRKTYS 262 GRNANF+G+ FA EF+ ++ KD++ WVK+ + APKLT++++ L+ + + T+S Sbjct: 209 GRNANFTGEHFADQEFDVNAVTEKDFNSWVKKTQNEAPKLTKEKYDELMLPENVDELTFS 268 Query: 263 STHLEF 268 STHL++ Sbjct: 269 STHLKY 274 >BH2064 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 Length = 329 Score = 195 bits (495), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 113/251 (45%), Positives = 158/251 (62%), Gaps = 9/251 (3%) Query: 25 TVLNPKGPSARTLSDTIILSILVMLGVLAVVYILYIFVLVKYRAKKSNEGYIPEHEEGNK 84 TVL+P+GP A SD I+LSI M+ ++ VV++L +LVKYR + +N+ Y P E G+ Sbjct: 27 TVLDPQGPVAEQQSDLIMLSIWFMIFIVLVVFVLLTVMLVKYRDRGNNDNYDPSIE-GSH 85 Query: 85 VLETXXXXXXXXXXAFLSVVTVKTTNAVENQAVEYKDQT-------PLVIYAASSNWKWH 137 LE LS+ TV T ++E +A E + PLVI+A S NWKW Sbjct: 86 KLEIIWTIVPIIIVTILSIPTVTTIYSLE-EAPEVSEVNAGNIQVEPLVIHATSVNWKWI 144 Query: 138 FSYPEEGIETVNYVNMPVHRAVEFRMYSFGSITSLWIPQLAGQKYAMSDMLTTLHLSADT 197 FSYPEE IETVNYVN+PV R V F++ S S+ S W+P L GQKY+M+ M T L+L + Sbjct: 145 FSYPEENIETVNYVNIPVDRPVLFKLTSADSMASFWVPHLGGQKYSMAGMETELYLMSHN 204 Query: 198 EGSYMGRNANFSGKGFAHMEFEALVMSSKDYDDWVKEVKETAPKLTEKEFKGLLATDYLG 257 G++ GRN+NF+G+GFA F ++++DYD WV+EV+ AP L+E+E+ L+ + Sbjct: 205 TGTFNGRNSNFTGEGFAEHRFVVNALTARDYDAWVEEVQTEAPPLSEEEYAHLMVPGHAE 264 Query: 258 RKTYSSTHLEF 268 T+SSTHLEF Sbjct: 265 EMTFSSTHLEF 275 >PA1317 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 Length = 331 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 77/219 (35%), Positives = 117/219 (53%), Gaps = 1/219 (0%) Query: 25 TVLNPKGPSARTLSDTIILSILVMLGVLAVVYILYIFVLVKYRAKKSNEGYIPEHEEGNK 84 T+ NPKG II + L+ML V+ V ++ + KYRA + Y P+ N+ Sbjct: 27 TLFNPKGQVGMDERTLIITATLLMLIVVIPVIVMTLAFAWKYRASNTQAEYKPDWHHSNR 86 Query: 85 VLETXXXXXXXXXXAFLSVVTVKTTNAVENQAVEYKDQTPLVIYAASSNWKWHFSYPEEG 144 + E A L +T ++T+ ++ + P+ I A S +WKW F YPE+G Sbjct: 87 I-EAVVWLVPCVIIAILGWITWESTHKLDPYRPLDSEVKPVTIQAVSLDWKWLFIYPEQG 145 Query: 145 IETVNYVNMPVHRAVEFRMYSFGSITSLWIPQLAGQKYAMSDMLTTLHLSADTEGSYMGR 204 I TVN + P V F++ S + S +IPQL Q Y+M+ M+T LHL A+ EG + G Sbjct: 146 IATVNEIAFPKDTPVNFQITSDSVMNSFFIPQLGSQIYSMAGMMTKLHLIANEEGVFDGI 205 Query: 205 NANFSGKGFAHMEFEALVMSSKDYDDWVKEVKETAPKLT 243 +AN+SG GF+ M F+A+ S + + DWV +VK L+ Sbjct: 206 SANYSGGGFSGMRFKAIATSEQGFQDWVAKVKAAPASLS 244 >AGc230 [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 Length = 218 Score = 134 bits (337), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 0/233 (0%), Positives = 0/233 (0%), Gaps = 12/233 (5%) Query: 25 TVLNPKGPSARTLSDTIILSILVMLGVLAVVYILYIFVLVKYRAKKSNEGYIPEHEEGNK 84 P R L + + V + + + G G + Sbjct: 44 FSAIPADIDERALDEQLERDGASPEEVALELARAKALAVSALHPEALVLGCDQTMALGTR 103 Query: 85 VLETXXXXXXXXXXAFLSVVTVKTTNAV----------ENQAVEYKDQTPLVIYAASSNW 134 + LS+ Q V + + +A Sbjct: 104 -VYHKPKNMAEAATHLLSLSGKVHRLNSAAVLVHNGKVVWQTVS-SAELAVRTLSAEFVS 161 Query: 135 KWHFSYPEEGIETVNYVNMPVHRAVEFRMYSFGSITSLWIPQLAGQKYAMSDMLTTLHLS 194 Sbjct: 162 221 Query: 195 ADTEGSYMGRNANFSGKGFAHMEFEALVMSSKDYDDWVKEVKETAPKLTEKEF 247 Sbjct: 222 274 >AGc2304 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Length = 218 Score = 134 bits (337), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 0/233 (0%), Positives = 0/233 (0%), Gaps = 12/233 (5%) Query: 25 TVLNPKGPSARTLSDTIILSILVMLGVLAVVYILYIFVLVKYRAKKSNEGYIPEHEEGNK 84 P R L + + V + + + G G + Sbjct: 44 FSAIPADIDERALDEQLERDGASPEEVALELARAKALAVSALHPEALVLGCDQTMALGTR 103 Query: 85 VLETXXXXXXXXXXAFLSVVTVKTTNAV----------ENQAVEYKDQTPLVIYAASSNW 134 + LS+ Q V + + +A Sbjct: 104 -VYHKPKNMAEAATHLLSLSGKVHRLNSAAVLVHNGKVVWQTVS-SAELAVRTLSAEFVS 161 Query: 135 KWHFSYPEEGIETVNYVNMPVHRAVEFRMYSFGSITSLWIPQLAGQKYAMSDMLTTLHLS 194 Sbjct: 162 221 Query: 195 ADTEGSYMGRNANFSGKGFAHMEFEALVMSSKDYDDWVKEVKETAPKLTEKEF 247 Sbjct: 222 274 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.311 0.129 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,904,531 Number of extensions: 982742 Number of successful extensions: 1310 Number of sequences better than 1.0e-05: 19 Number of HSP's gapped: 1297 Number of HSP's successfully gapped: 19 Length of query: 339 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 232 Effective length of database: 26,037,693 Effective search space: 6040744776 Effective search space used: 6040744776 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 116 (49.3 bits)