BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0391.0026.p (871 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2845 [T] COG0639 Diadenosine tetraphosphatase and related seri... 167 5e-41 DR2249_2 [T] COG0639 Diadenosine tetraphosphatase and related se... 158 5e-38 alr3731_2 [T] COG0639 Diadenosine tetraphosphatase and related s... 157 5e-38 alr3731_1 [R] COG4639 Predicted kinase 94 1e-18 DR2249_1 [R] COG4639 Predicted kinase 60 2e-08 >BH2845 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 167 bits (424), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 18/239 (7%), Positives = 43/239 (17%), Gaps = 9/239 (3%) Query: 208 DVIGDIHGCYDEMLELLGQLGYAPDDAGLYRHPGGRTLVSVGDVMSRGPKSLDTLRFWKK 267 I + G + + +++ R + Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQ-NSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQ 62 Query: 268 HCDAGTARMIDSNHGWKIARYLSGRQVTLSHGDEHIXXXXXXXXXXXXXXXXXXXXXXXK 327 + HG + ++ + S ++ Sbjct: 63 GLTETYVGNWLAKHGSREKLIIASKVSGPSRNND----KGIRPDQALDRKNIREALHDSL 118 Query: 328 QFLLSAPSHLVLCREGVRRVVVAHAGIRDEYIGKQSKRIQDFCRYGDTDG-MDATGAPVR 386 + L + L + + Y S D G Sbjct: 119 KRLQTDYLDLYQVHW---PQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRY 175 Query: 387 KEWYVEHESGELIVWGHDPRPFPTVVKNTVNIDQGAVFGGSLTAYRYPEQKFVSVKAYQ 445 E G + + + N + + + V + AY Sbjct: 176 IGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYS 234 >DR2249_2 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 158 bits (399), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 15/249 (6%), Positives = 37/249 (14%), Gaps = 14/249 (5%) Query: 208 DVIGDIHGCYDEMLELLGQLGYAPDDAGLYRHPGGRTLVSVGDVMSRGPKSLDTLRFWKK 267 I + G +A + + +++ R + Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLD-YAVAQGINLIDVAEMYPVPPRPETQ 62 Query: 268 HCDAGTARMIDSNHGWKIARYLSGRQVTLSHGDEHIXXXXXXXXXXXXXXXXXXXXXXXK 327 + HG + ++ + S ++ Sbjct: 63 GLTETYVGNWLAKHGSREKLIIASKVSGPSRNND--------KGIRPDQALDRKNIREAL 114 Query: 328 QFLLSAPSHLVLCREGVRRVVVAHAGIRDEYIGKQSKRIQDFCRYGDTDG-MDATGAPVR 386 L L +V S A Sbjct: 115 HDSLKRLQTDYLDLY---QVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAG 171 Query: 387 KEWYVEHESGELIVWGHDPRPFPTVVKNTVNIDQGAVFGGSLTAYRYPEQKFVSVKAYQD 446 K Y+ + + Q + + + Sbjct: 172 KIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELL 231 Query: 447 YARDPDSPL 455 Sbjct: 232 AYS-CLGFG 239 >alr3731_2 [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Length = 346 Score = 157 bits (398), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 14/250 (5%), Positives = 36/250 (14%), Gaps = 16/250 (6%) Query: 208 DVIGDIHGCYDEMLELLGQLGYAPD--------DAGLYRHPGGRTLVSVGDVMSRGPKSL 259 I + G D + + + + V R Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 260 DTLRFWKKHCDAGTARMIDSNHGWKIARYLSGRQVTLSHGDEHIXXXXXXXXXXXXXXXX 319 T + +R + + Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALD----RKNIREALHDSLK 119 Query: 320 XXXXXXXKQFLLSAPSHLVLCREGVRRVVVAHAGIRDEYIGKQSKRIQDFCRYGDTDG-M 378 + + P G ++ + + + + Sbjct: 120 RLQTDYLDLYQVHWPQRPTN-CFG--KLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYI 176 Query: 379 DATGAPVRKEWYVEHESGELIVWGHDPRPFPTVVKNTVNIDQGAVFGGSLTAYRYPEQKF 438 + H + + + P + N A Sbjct: 177 GVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCL 236 Query: 439 VSVKAYQDYA 448 Y Sbjct: 237 GFGTLTGKYL 246 >alr3731_1 [R] COG4639 Predicted kinase Length = 179 Score = 94.0 bits (232), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 61/181 (33%), Positives = 91/181 (50%), Gaps = 23/181 (12%) Query: 11 IPFPHGGIVVLVGPSNSGKTTLLRRLVQEGVLLQTEIVSSDDYRTLVGDVEYIDWKGRPR 70 I P +VVL+G S +GK+T R+ Q E++SSD R LV + E Sbjct: 3 ITIPELSLVVLIGASGAGKSTFARKHFQP-----FEVISSDFCRGLVSNDE--------- 48 Query: 71 EEADILYSDYQLLSNLAFEAMNTVVSMRCRLGKLTVVDATHLQPEYRRKYIDLAAGHDLP 130 + Q S AF+ ++ + + R GKLTV+DAT++QPE R+ + +A + Sbjct: 49 --------NSQSASRDAFDVLHYITTKRLAAGKLTVIDATNVQPEDRKTLLQMAKQYHCF 100 Query: 131 CAAWILDLPEQTLLERDTSR-DQPRGRQRVKQQFVQFKRSLRGLRDEGFDFTYMLKETES 189 A + DLPE+ ER+ R D+ G V++ +RSLR L EGF + Y LK E Sbjct: 101 TVAIVFDLPEELCHERNQQRSDRQFGSHVVRRHTQMLRRSLRSLEKEGFRYVYTLKSPEE 160 Query: 190 V 190 + Sbjct: 161 I 161 >DR2249_1 [R] COG4639 Predicted kinase Length = 186 Score = 59.7 bits (143), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 48/181 (26%), Positives = 76/181 (41%), Gaps = 34/181 (18%) Query: 11 IPFPHGGIVVLVGPSNSGKTTLLRRLVQEGVLLQTEIVSSDDYRTLVGDVEYIDWKGRPR 70 I P +V LVG S SGK+T R Q +L+ E Sbjct: 19 IDLPALALVALVGASASGKSTFAARQFQPDEVLRVE------------------------ 54 Query: 71 EEADILYSDYQLL--SNLAFEAMNTVVSMRCRLGKLTVVDATHLQPEYRRKYIDLAAGHD 128 D+Q ++ A + + T + R GKLTV++A ++P RR+ ++LA HD Sbjct: 55 --------DFQRAGEADAALDNLYTAAAQRLAQGKLTVIEANLVRPADRRRLVELARAHD 106 Query: 129 LPCAAWILDLPEQTLLERDTSRDQPRGRQRVKQQFVQFKRSLRGLRDEGFDFTYMLKETE 188 + A + DL L R +R+ + Q + +R+ RGL EGF + L + Sbjct: 107 VAPVAIVFDLARSLLEARLAARECCPELLDLTSQVAELRRTRRGLPQEGFRQVWTLDSPQ 166 Query: 189 S 189 + Sbjct: 167 A 167 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 66,045,748 Number of extensions: 2864927 Number of successful extensions: 34453 Number of sequences better than 1.0e-05: 11 Number of HSP's gapped: 34462 Number of HSP's successfully gapped: 11 Length of query: 871 Length of database: 38,378,431 Length adjustment: 115 Effective length of query: 756 Effective length of database: 25,115,021 Effective search space: 18986955876 Effective search space used: 18986955876 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 120 (50.8 bits)