BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0391.0018.p
         (340 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

TM0587_3 [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase     159   4e-39
TM0587_1 [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase      57   4e-08
MJ1633_2 [R] COG0618 Exopolyphosphatase-related proteins               52   1e-06
MA1171_2 [R] COG0618 Exopolyphosphatase-related proteins               50   7e-06

>TM0587_3 [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase
          Length = 346

 Score =  159 bits (403), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 17/242 (7%), Positives = 39/242 (16%), Gaps = 2/242 (0%)

Query: 99  KQVILVDHNERQQSANDIDQVRVVEVIDHHRIANFETAHPLYYRAEPVGCTATILNKLYK 158
            Q   + H+  + S   +  +   E                             +    +
Sbjct: 1   MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60

Query: 159 ENGVAIPKDIAGLMLSAIISDSLLFKSPTCTEQDVAAARELAGIAGVDADSYGLAMLKAG 218
             G+        L         ++    +   ++                   L      
Sbjct: 61  TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKR 120

Query: 219 ADL-SDKTIAQLISLDAKEFKMGEYKVEIAQVNAVDVNDVLSKQAELETALTAIIDDKGL 277
                                            AV + D L   AE + A          
Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSN 180

Query: 278 DLFLFVVTDILNNDSVGLALGRVAGAVEQAYNVKLDDNKALLKGVVSRKSQIVPVLTETI 337
           +    V+  +   D        V      +   +  +              +        
Sbjct: 181 ETAFGVMRYLHLADKH-DLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFG 239

Query: 338 AK 339
             
Sbjct: 240 TL 241


>TM0587_1 [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase
          Length = 346

 Score = 57.0 bits (136), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 2/57 (3%), Positives = 8/57 (14%), Gaps = 2/57 (3%)

Query: 31 MEKTLIFGHKNPDTDTICSAIAYAALKK--ELGWDAEPVRLGEISGETQYALDHFGV 85
            +       +   D   +                    +    +    +   H   
Sbjct: 23 FGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSR 79


>MJ1633_2 [R] COG0618 Exopolyphosphatase-related proteins
          Length = 346

 Score = 52.0 bits (123), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 8/164 (4%), Positives = 27/164 (16%), Gaps = 7/164 (4%)

Query: 35  LIFGHKNPDTDTICSAIAYAALKKELGWDAEPVRLGEIS-GETQYALDHFGVKAPRLVEN 93
           +        T  + +        +          + +         +     +       
Sbjct: 6   IPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPET-QGL 64

Query: 94  VASEAKQVI-LVDHNERQQSANDIDQVRVVEVIDHHRIANFETAHPLYYRAEPVGCTATI 152
             +     +      E+   A+ +         D     +         R   +  +   
Sbjct: 65  TETYVGNWLAKHGSREKLIIASKVSGPSR--NNDKGIRPDQ-ALDRKNIREA-LHDSLKR 120

Query: 153 LNKLYKENGVAIPKDIAGLMLSAIISDSLLFKSPTCTEQDVAAA 196
           L   Y +                +                + A 
Sbjct: 121 LQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDAL 164


>MA1171_2 [R] COG0618 Exopolyphosphatase-related proteins
          Length = 346

 Score = 49.7 bits (117), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 10/163 (6%), Positives = 24/163 (14%), Gaps = 4/163 (2%)

Query: 39  HKNPDTDTICSAIAYAALKKELGWDAEPVRLGEISGETQYAL-DHFGVKAPRLVENVASE 97
           H+ P +    S +    +                    Q           P         
Sbjct: 4   HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63

Query: 98  AKQVILVDHNERQQSANDIDQVRVVEVIDHHRIANFETAHPLYYRAEP-VGCTATILNKL 156
             +  + +   +  S   +     V     +             R         ++    
Sbjct: 64  LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQA-LDRKNIREALHDSLKRLQ 122

Query: 157 YKENGVAIPKDIAGLMLSAIISDSLLFKSPTCTEQDVAAAREL 199
                +                      S       +     L
Sbjct: 123 TDYLDLYQVHWPQRPTNCFGKLGYSWTDSAP-AVSLLDTLDAL 164


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.317    0.133    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 23,098,658
Number of extensions: 887374
Number of successful extensions: 3274
Number of sequences better than 1.0e-05: 7
Number of HSP's gapped: 3279
Number of HSP's successfully gapped: 7
Length of query: 340
Length of database: 38,378,431
Length adjustment: 107
Effective length of query: 233
Effective length of database: 26,037,693
Effective search space: 6066782469
Effective search space used: 6066782469
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 116 (49.3 bits)