BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0391.0012.p (364 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yqiT [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 583 e-166 BH2765 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 540 e-153 all0426 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 342 5e-94 PA3418 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 303 3e-82 BH0218 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 299 5e-81 >BS_yqiT [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 583 bits (1504), Expect = e-166, Method: Compositional matrix adjust. Identities = 0/364 (0%), Positives = 0/364 (0%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 M + + + + + G + Sbjct: 1 MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITG 60 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 + + +Q L Y + + Sbjct: 61 IDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLL 120 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 ++ + + A A + S G V + Sbjct: 121 NPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWR 180 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 + + + + L Sbjct: 181 TTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLA 240 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNG 300 Sbjct: 241 300 Query: 301 YNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERISLLKNSRSTFLRDGHHV 360 Sbjct: 301 360 Query: 361 LSRR 364 Sbjct: 361 364 >BH2765 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 540 bits (1390), Expect = e-153, Method: Compositional matrix adjust. Identities = 0/364 (0%), Positives = 0/364 (0%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 M + + + + + G + Sbjct: 1 MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITG 60 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 + + +Q L Y + + Sbjct: 61 IDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLL 120 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 ++ + + A A + S G V + Sbjct: 121 NPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWR 180 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 + + + + L Sbjct: 181 TTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLA 240 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNG 300 Sbjct: 241 300 Query: 301 YNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERISLLKNSRSTFLRDGHHV 360 Sbjct: 301 360 Query: 361 LSRR 364 Sbjct: 361 364 >all0426 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 342 bits (878), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 0/344 (0%), Positives = 0/344 (0%), Gaps = 5/344 (1%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 M + + + + + G + Sbjct: 1 MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITG 60 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 + +A+ F + + Sbjct: 61 IDSSPAMIAEARSALPDCQFVEADIRNW-QPVQALDLIFANASLQWLPDHYELFPHLVSL 119 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 + + + + Y A + + Sbjct: 120 LNPQGVLAVQMPDNWLEP---THVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEV 176 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALG 240 + + + VT + + ++ Sbjct: 177 DIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQ 236 Query: 241 ATINDDSLPLLQAKVIAGAANNQLKEPR-HGDALHKMGIVYAPDYVINSGGVINVADELN 299 Sbjct: 237 296 Query: 300 GYNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERI 343 Sbjct: 297 340 >PA3418 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 303 bits (776), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 0/342 (0%), Positives = 0/342 (0%), Gaps = 13/342 (3%) Query: 3 LFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALRLS 62 + A L A + + + LG + A + A Sbjct: 1 MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITG 60 Query: 63 KGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTEAD 122 + + + D + + Sbjct: 61 IDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLL 120 Query: 123 MDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQGVG 182 + + G + Sbjct: 121 NPQGVLAVQMPDNWL----EPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEV 176 Query: 183 NVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYGATAVDPADIISVKSDIYAPCALGAT 242 ++ T + +I + + + P Sbjct: 177 DIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQ 236 Query: 243 INDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINVADELNGYN 302 Sbjct: 237 296 Query: 303 KDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLAQERIS 344 Sbjct: 297 --------- 329 >BH0218 [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase Length = 252 Score = 299 bits (766), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 0/345 (0%), Positives = 0/345 (0%), Gaps = 9/345 (2%) Query: 1 MELFAAMERDDYEELLFCQDKASGLKAIIAIHDTTLGPALGGTRMWTYASEEDAIVDALR 60 + E L + A + L + D+ + Sbjct: 12 FSAERSRP--AVELLARVPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIA 69 Query: 61 LSKGMTYKNAVAGLNLGGGKTVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 120 ++ ++ + V D + + + + V + Sbjct: 70 EARSALPDCQFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQ 129 Query: 121 ADMDIIHQETDYVTGISATYGSSGNPSPATAFGVYQGMKAAAKAAFGSDSLEGRRVAVQG 180 + + + ++ A + + Sbjct: 130 MPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPS 189 Query: 181 VGNVSFTLCKYLHEEGAQLIVTDINKDAVKRAVEAYG------ATAVDPADIISVKSDIY 234 + + Q + + + + Sbjct: 190 HQAIIDWVTATGLRPWLQDLTESE-QQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVA 248 Query: 235 APCALGATINDDSLPLLQAKVIAGAANNQLKEPRHGDALHKMGIVYAPDYVINSGGVINV 294 Sbjct: 249 308 Query: 295 ADELNGYNKDRAYKQIAKIYDSITRILEISATSGIPAYAAADHLA 339 Sbjct: 309 353 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.133 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 26,413,291 Number of extensions: 1135640 Number of successful extensions: 2599 Number of sequences better than 1.0e-05: 35 Number of HSP's gapped: 2532 Number of HSP's successfully gapped: 35 Length of query: 364 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 256 Effective length of database: 25,922,359 Effective search space: 6636123904 Effective search space used: 6636123904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 116 (49.3 bits)