BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0391.0004.p (597 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_kinB [T] COG0642 Signal transduction histidine kinase 175 2e-43 BS_kinA_3 [T] COG0642 Signal transduction histidine kinase 141 3e-33 BS_kinC_2 [T] COG0642 Signal transduction histidine kinase 120 5e-27 atoS_3 [T] COG0642 Signal transduction histidine kinase 120 8e-27 BB0764_2 [T] COG0642 Signal transduction histidine kinase 100 7e-21 >BS_kinB [T] COG0642 Signal transduction histidine kinase Length = 429 Score = 175 bits (444), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 110/235 (46%), Positives = 141/235 (60%), Gaps = 16/235 (6%) Query: 368 NELQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLL------SEKSSGDERKYLSMALS 421 ++L SEKM I+SELAASVAHEVRNPL V RGF+QLL KSS D +K + LS Sbjct: 202 SQLIHSEKMTIVSELAASVAHEVRNPLTVVRGFVQLLFNDETLQNKSSADYKK---LVLS 258 Query: 422 ELDRASNIITDFLTFAKPEF--EKISQLSVLDECKHIESIMLPLCHLNGGKMVLEVTGDL 479 ELDRA IIT++L AK + +++ LS L K S+M+ + + E DL Sbjct: 259 ELDRAQGIITNYLDMAKQQLYEKEVFDLSAL--IKETSSLMVSYANYKSVTVEAETEPDL 316 Query: 480 WVKGNSSKFKQAFINMIKNSIESLGE-DGSIHIKAYAKGDKVFIHIKDNGAGMDPAVLSR 538 + G+++K KQA IN++KNSIE++ G IHI A G + I+I DNG GM + + Sbjct: 317 LIYGDATKLKQAVINLMKNSIEAVPHGKGMIHISAKRNGHTIMINITDNGVGMTDHQMQK 376 Query: 539 LGEPYFSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILPLAEAPE 593 LGEPY+S KT GTGLGL VTF IIE G + F SS GT LP A+ P Sbjct: 377 LGEPYYSL-KTNGTGLGLTVTFSIIEHHHGTISFNSSFQKGTTVTIKLP-ADLPH 429 >BS_kinA_3 [T] COG0642 Signal transduction histidine kinase Length = 236 Score = 141 bits (356), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 79/211 (37%), Positives = 124/211 (58%), Gaps = 4/211 (1%) Query: 372 RSEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKSSGDERKYLSMALSELDRASNIIT 431 +SEK+ I +LAA +AHE+RNPL +GFLQL+ G+E Y + SEL R I++ Sbjct: 19 KSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGNEH-YFDIVFSELSRIELILS 77 Query: 432 DFLTFAKPEFEKISQ-LSVLDECKHIESIMLPLCHLNGGKMVLEVTGD-LWVKGNSSKFK 489 + L AKP+ + + L++ + +++ +LNG + D +++ G+ ++ K Sbjct: 78 ELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQANLNGIFIRTSYEKDSIYINGDQNQLK 137 Query: 490 QAFINMIKNSIESLGEDGSIHIKAYAKGDKVFIHIKDNGAGMDPAVLSRLGEPYFSSNKT 549 Q FIN+IKN++ES+ + G++ I V + +KD G G+ VL+R+GEP+ ++ K Sbjct: 138 QVFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIPEKVLNRIGEPFLTT-KE 196 Query: 550 KGTGLGLMVTFRIIEAMGGEVRFISSKGAGT 580 KGTGLGLMVTF IIE G + S GT Sbjct: 197 KGTGLGLMVTFNIIENHQGVIHVDSHPEKGT 227 >BS_kinC_2 [T] COG0642 Signal transduction histidine kinase Length = 248 Score = 120 bits (302), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 84/232 (36%), Positives = 127/232 (54%), Gaps = 9/232 (3%) Query: 362 ELELFNNELQR-SEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKSSGDERKYLSMAL 420 EL N L R S+K+ I SELAA +AHEVRNPL GFLQ++ + D + Y + Sbjct: 17 ELIEINERLARESQKLSITSELAAGIAHEVRNPLTSVSGFLQIMKTQYP-DRKDYFDIIF 75 Query: 421 SELDRASNIITDFLTFAKPE---FEKISQLS-VLDECKHIESIMLPLCHLNGGKMVLEVT 476 SE+ R ++++ L AKP+ F K QL+ +L + + L ++ K E Sbjct: 76 SEIKRIDLVLSELLLLAKPQAITF-KTHQLNEILKQVTTLLDTNAILSNIVIEKNFKETD 134 Query: 477 GDLWVKGNSSKFKQAFINMIKNSIESLGEDGSIHIKAYAKGDKVFIHIKDNGAGMDPAVL 536 G + G+ ++ KQ FIN+IKN IE++ + G + I I +KD G GM L Sbjct: 135 G-CMINGDENQLKQVFINIIKNGIEAMPKGGVVTISTAKTASHAVISVKDEGNGMPQEKL 193 Query: 537 SRLGEPYFSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILPL 588 ++G+P++S+ K KGTGLGL + RI++ GE++ S G G+ +LPL Sbjct: 194 KQIGKPFYST-KEKGTGLGLPICLRILKEHDGELKIESEAGKGSVFQVVLPL 244 >atoS_3 [T] COG0642 Signal transduction histidine kinase Length = 278 Score = 120 bits (300), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 72/233 (30%), Positives = 130/233 (55%), Gaps = 14/233 (6%) Query: 370 LQRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEKSSGD-ERKYLSMALSELDRASN 428 + ++E++ + EL A VAHEVRNPL RG++Q+L +++S ++YLS+ L E+D + Sbjct: 50 MAQAERLATLGELMAGVAHEVRNPLTAIRGYVQILRQQTSDPIHQEYLSVVLKEIDSINK 109 Query: 429 IITDFLTFAKPEFEKISQLSVLDECKHIESIMLPLCHLNGGKMVLEVTGDL-----WVKG 483 +I L F++P + Q+S+ + L L G + ++ +L + Sbjct: 110 VIQQLLEFSRPRHSQWQQVSL----NALVEETLVLVQTAGVQARVDFISELDNELSPINA 165 Query: 484 NSSKFKQAFINMIKNSIESLGEDGSIHIKAYAKGD-KVFIHIKDNGAGMDPAVLSRLGEP 542 + KQ +N++ N+++++ G I I+ + D + I I+DNG G+D ++ ++ +P Sbjct: 166 DRELLKQVLLNILINAVQAISARGKIRIQTWQYSDSQQAISIEDNGCGIDLSLQKKIFDP 225 Query: 543 YFSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILPLAEAPEGS 595 +F++ K GTGLGL ++ RII A G++R S G G ILP+ P+G+ Sbjct: 226 FFTT-KASGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPI--NPQGN 275 >BB0764_2 [T] COG0642 Signal transduction histidine kinase Length = 282 Score = 100 bits (249), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 71/234 (30%), Positives = 121/234 (51%), Gaps = 25/234 (10%) Query: 371 QRSEKMEIISELAASVAHEVRNPLQVTRGFLQLLSEK------SSGDERKYLSMALSELD 424 +R E + + A ++AHE++NPL LQLL ++ +G Y + E++ Sbjct: 45 RRVEALASFTRHARNIAHEIKNPLGAIDINLQLLKKEIEKQKMKNGKAENYFKVIKEEIN 104 Query: 425 RASNIITDFLTFAKPEFEKISQLSVLDECKHIESIMLPLCHL-NGG------KMVLEVTG 477 R I+T+FL +P + + + K I+ ++ +C L N G K++L + Sbjct: 105 RVDKIVTEFLLTVRP-------IKINLQEKDIKQVIGSVCELLNPGLENKHIKLLLNLNK 157 Query: 478 DLWVKGNSSKFKQAFINMIKNSIESL----GEDGSIHIKAYAKGDKVFIHIKDNGAGMDP 533 + + KQ IN++KN+ E+L E I I + K +K+ I+IKDNG G+ Sbjct: 158 ISNILIDEKLLKQVIINIVKNAEEALLETKKEIKKIEIFLFEKDNKIHINIKDNGNGIKD 217 Query: 534 AVLSRLGEPYFSSNKTKGTGLGLMVTFRIIEAMGGEVRFISSKGAGTESITILP 587 V + +P FS+ K KG+G+GL ++++II+ +GGE+ S +G GT LP Sbjct: 218 GVKEEIFKPQFST-KEKGSGIGLTISYKIIKELGGEIFVESKEGKGTIFTITLP 270 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 40,879,848 Number of extensions: 1603648 Number of successful extensions: 4027 Number of sequences better than 1.0e-05: 204 Number of HSP's gapped: 3828 Number of HSP's successfully gapped: 204 Length of query: 597 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 485 Effective length of database: 25,461,023 Effective search space: 12348596155 Effective search space used: 12348596155 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 119 (50.4 bits)