BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0389.0012.p (436 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA1749 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 376 e-104 YLR027c [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase 58 2e-08 sll0402 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 58 3e-08 Ta0765 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 54 4e-07 SP0035 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 54 5e-07 >SA1749 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 428 Score = 376 bits (965), Expect = e-104, Method: Compositional matrix adjust. Identities = 191/432 (44%), Positives = 271/432 (62%), Gaps = 7/432 (1%) Query: 4 MNPLAGQLNDSIKAGNEHVYDMLSNLGKALYYPKEGILSQSXXXXXXXXXXXXTIGIATE 63 MNPLA LN+ ++ N + MLS+LG+ ++YPK GILSQS TIG+AT Sbjct: 1 MNPLAQSLNEQLQQSNATAFTMLSDLGQNMFYPK-GILSQSAEAKSTTYNA--TIGMATN 57 Query: 64 HGVPMHLGVIQDKLSAYSPKDLYGYAPPAGKPELRTLWREKMLRETPSLEGKSFGNPIAT 123 M + + +P +++ YAPP G ELR LW++KMLR+ P L + PI T Sbjct: 58 KDGKMFASSLDAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSLPIVT 117 Query: 124 NALTHGLSIVADLFADQGDAVIYPDKNWENYELTFGVRRLSDTVNYPLFTEDMSFNSEGL 183 NALTHGLS+V DLF +QGD ++ P+ NW NY+L F R ++ YP+F +D + ++ L Sbjct: 118 NALTHGLSLVGDLFVNQGDTILLPEHNWGNYKLVFNTRNGANLQTYPIFDKDGHYTTDSL 177 Query: 184 LDALLAQKERGKAIVLLNFPNNPTGYTPGIKEGEAIVAAILRAAEEGINVVVVSDDAYFG 243 ++AL + + K I++LN+PNNPTGYTP KE IV AI A++G V+ V DDAY+G Sbjct: 178 VEALQSYN-KDKVIMILNYPNNPTGYTPTHKEVTTIVDAIKALADKGTKVIAVVDDAYYG 236 Query: 244 LFFEDSLKESLFGRLANLHPR-VLAVKIDGATKEEFVWGFRVGFITYASDSKEVLAALEQ 302 LF+ED +SLF L+NL+ +L V++DGATKE F WGFRVGF+T+ + + LE Sbjct: 237 LFYEDVYTQSLFTALSNLNSNAILPVRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEA 296 Query: 303 KTMGIIRATISSGPHPSQTFVLDALK-SPEFAEQKEEKFQIMKGRANKVKALLDSGKYGD 361 K G+IR+ ISSGP P+Q+ V LK + +F ++ E+ Q +K R K ++ + +Y Sbjct: 297 KVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHS 356 Query: 362 EVWTYYPFNSGYFMCLKLHTVPADALRLHLIHNYGLGTIALGETDLRVAFSCIEEDQLED 421 W Y FNSGYFM +K+H V + LR HLI Y +G IAL TD+R+AFSC+E++ + Sbjct: 357 H-WQAYDFNSGYFMAIKVHDVDPEELRKHLIEKYSIGVIALNATDIRIAFSCVEKEDIPH 415 Query: 422 LFDMVYAGIRDL 433 +FD + I DL Sbjct: 416 VFDSIAKAIDDL 427 >YLR027c [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase Length = 432 Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 66/242 (27%), Positives = 98/242 (40%), Gaps = 26/242 (10%) Query: 127 THGLSIVADLFADQGDAVIYPDK-------NWENYELTFGVRRLSDTVNYPLF-TEDMSF 178 T L I A F+ +PDK W N+ F + L T YP + E S Sbjct: 123 TGALHISAKFFSK-----FFPDKLVYLSKPTWANHMAIFENQGLK-TATYPYWANETKSL 176 Query: 179 NSEGLLDALLAQKERGKAIVLLNFPNNPTGYTPGIKEGEAIVAAILRAAEEGINVVVVSD 238 + G L+A+ E G VL + +NPTG P ++ IV AI N + + D Sbjct: 177 DLNGFLNAIQKAPE-GSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASK-----NHIALFD 230 Query: 239 DAYFGLFFEDSLKESLFGRLA--NLHPRVLAVKIDGATKEEFVWGFRVGF----ITYASD 292 AY G D K++ RL L K ++G RVG +T + Sbjct: 231 TAYQGFATGDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQ 290 Query: 293 SKEVLAALEQKTMGIIRATISSGPHPSQTFVLDALKSPEFAEQKEEKFQIMKGRANKVKA 352 +K + A+ + IIR+ +S+ P V L++PE EQ + M R K++ Sbjct: 291 NKTIKPAVTSQLAKIIRSEVSNPPAYGAKIVAKLLETPELTEQWHKDMVTMSSRITKMRH 350 Query: 353 LL 354 L Sbjct: 351 AL 352 >sll0402 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 389 Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 58/202 (28%), Positives = 93/202 (46%), Gaps = 16/202 (7%) Query: 88 YAPPAGKPELRTLWREKMLRETPSLEGKSFGNPIATNALTHGLSIVADLFADQGDAVIYP 147 Y P AG+P LR +K LRE +L ++ N + TN H L + +QGD VI P Sbjct: 63 YGPAAGEPALRQAIAKK-LREKNNLPYEA-ANILVTNGGKHSLFNLMLAMIEQGDEVIIP 120 Query: 148 DKNWENYELTFGVRRLSDTVNYPLFTEDMSFNSEGLLDALLAQKERGKAIVLLNFPNNPT 207 W +Y + + + D E L A+ ++ + + +LN P+NPT Sbjct: 121 APYWLSYPEMVRLAEGTPVIVNTTAATDYKITPEQLRQAITSKSK----LFVLNSPSNPT 176 Query: 208 G--YTPGIKEGEAIVAAILRAAEEGINVVVVSDDAYFGLFFEDSLKESLFGRLANLHPRV 265 G YTP E A+ A IL E ++ VVSD+ Y + ++ + S+ + R Sbjct: 177 GAVYTPA--EIRALAAVIL----EYEDLYVVSDEIYERILYDGTEHLSIGAVNDEIFQRT 230 Query: 266 LAVKIDGATKEEFVWGFRVGFI 287 + +G K + G+RVG++ Sbjct: 231 IIS--NGFAKSYSMTGWRVGYL 250 >Ta0765 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 385 Score = 54.3 bits (129), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 72/271 (26%), Positives = 120/271 (44%), Gaps = 40/271 (14%) Query: 66 VPMHLGV-IQDKLSAYSPKDLYGYAPPAGKPELRTLWREKMLRETPSLEGKSFGNPIATN 124 +P H+ + I+D L K+ Y G PELR EK++++ + + N + +N Sbjct: 48 IPEHVRLAIEDALK----KNRTHYTDSTGIPELRKAIAEKLVKKN-GIRSATPENVLVSN 102 Query: 125 ALTHGLSIVADLFADQGDAVIYPDKNWENYELTFGVRRLSD--TVNYPL--FTEDMSFNS 180 + L I G+ VI PD W + +L+D + P+ + E+M Sbjct: 103 GGMNALYITFRSLIAPGEKVIIPDPMWTEIA---EIIKLADGIPIRIPVERYVEEMR--- 156 Query: 181 EGLLDALLAQKERGKAIVLLNFPNNPTGYTPGIKEGEAIVAAILRAAEEGINVVVVSDDA 240 +R +A V +N P+NPTGY G K+ ++ I+ AE + +VSD+A Sbjct: 157 ------KYENDDRVRA-VFINSPHNPTGYVFGEKQ----ISDIIDFAESK-GIFIVSDEA 204 Query: 241 YFGLFFEDSLKESLFGRLANLHPRVLAVKIDGATKEEFVWGFRVGFITYASDSKEVLAAL 300 Y + F D LK G L + + + +K + G R+G YA S E+L Sbjct: 205 YEDVIF-DGLKHLSPGSLYD-----DTISLFSMSKSYAMSGLRIG---YAHTSNEILYDR 255 Query: 301 EQKTMGIIRATISSGPHPSQTFVLDALKSPE 331 +K ++R TI+ +Q + AL P+ Sbjct: 256 MKK---LLRCTINGVNSATQYGAVAALTGPQ 283 >SP0035 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 389 Score = 53.9 bits (128), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 53/172 (30%), Positives = 80/172 (46%), Gaps = 22/172 (12%) Query: 121 IATNALTHGLSIVADLFADQGDAVIYPDKNWENYELTFG-----VRRLSDTVNYPLFTED 175 + T T LS ++GD V+ P + YE + + T N + T + Sbjct: 95 LVTIGATEALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPE 154 Query: 176 MSFNSEGLLDALLAQKERGKAIVLLNFPNNPTGYTPGIKEGEAIVAAILRAAEEGINVVV 235 M L A+L Q ++ KA V+LN+P NPTG T ++ EA+ AA+LR E + V Sbjct: 155 M------LEKAILEQGDKLKA-VILNYPANPTGITYSREQLEAL-AAVLRKYE----IFV 202 Query: 236 VSDDAYFGLFFEDSLKESLFGRLANLHPRVLAVKIDGATKEEFVWGFRVGFI 287 V D+ Y L + SL L R A+ I+G +K + G+R+G I Sbjct: 203 VCDEVYSELTYTGEAHVSLGTML-----RDQAIIINGLSKSHAMTGWRLGLI 249 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.137 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 32,887,343 Number of extensions: 1334547 Number of successful extensions: 2568 Number of sequences better than 1.0e-05: 18 Number of HSP's gapped: 2587 Number of HSP's successfully gapped: 18 Length of query: 436 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 327 Effective length of database: 25,807,025 Effective search space: 8438897175 Effective search space used: 8438897175 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 117 (49.7 bits)