BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0389.0010.p (457 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4165 [KE] COG1167 Transcriptional regulators containing a DNA-... 154 2e-37 RSc3119 [KE] COG1167 Transcriptional regulators containing a DNA... 148 1e-35 BH1940 [KE] COG1167 Transcriptional regulators containing a DNA-... 137 3e-32 mlr6174 [KE] COG1167 Transcriptional regulators containing a DNA... 134 3e-31 YPO2845 [KE] COG1167 Transcriptional regulators containing a DNA... 134 3e-31 >PA4165 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 496 Score = 154 bits (390), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 91/212 (42%), Positives = 120/212 (56%), Gaps = 13/212 (6%) Query: 244 FPYAEW----RSALKYAGGKSGGLLEGYCPPQGEEGLRRAIAAHLRVTRGIRAEAEHIVL 299 FP A W R LK G ++ L G PQG E LR+AIA ++ + RG RA A+ +++ Sbjct: 144 FPLATWERLQRQVLKEYGARA--LTHG--DPQGAEPLRQAIADYVNLERGARATADRVLV 199 Query: 300 FSGSMQGIVLLAQLLLEPGSPAVVEDPGFHGIRRAVEISGGELLLGRVDESGLVP----- 354 + S Q + L A +LL+ G VEDP ++G R+A E +G E L VDE GL P Sbjct: 200 LTSSQQALGLCASVLLDAGERIFVEDPAYYGARKAFEAAGLECLPVPVDEQGLRPEPILA 259 Query: 355 QDWAARLLFVTPSRQFPTGAVLPXXXXXXXXXXXXXXXXXIVEDDYDSEFRWGGRPIEPL 414 Q AAR L +TPS +PTG L I+EDDYDSEF + GRP + Sbjct: 260 QPQAARALCLTPSHHYPTGVTLSLERRLALIEWAQRQQAWIIEDDYDSEFHYAGRPTACV 319 Query: 415 KALDHEERVIYIGSFSNSMFSGLRLGYAVLPP 446 + LD ER +YIG+F+ S+F GLR+GY VLPP Sbjct: 320 QGLDAHERTLYIGTFTKSLFPGLRIGYMVLPP 351 >RSc3119 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 488 Score = 148 bits (374), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 83/218 (38%), Positives = 119/218 (54%), Gaps = 5/218 (2%) Query: 244 FPYAEWRSALKYAGGKSGGLLEGYCPPQGEEGLRRAIAAHLRVTRGIRAEAEHIVLFSGS 303 FP A+WR ++ A G GY P +G LR+AIA +LRV+RG+R EA + + G+ Sbjct: 135 FPLAQWRRCVERAWRSIGPAQLGYMPVEGNAALRQAIAEYLRVSRGVRCEARQVFITDGT 194 Query: 304 MQGIVLLAQLLLEPGSPAVVEDPGFHGIRRAVEISGGELLLGRVDESGLV--PQDW---A 358 + L A+ L + A +E+PG+ G R A + + L VD GL P+DW Sbjct: 195 QNSLDLCARTLADADDTAWIENPGYSGARHAFQAANLRLAPIPVDADGLAPRPEDWRDRP 254 Query: 359 ARLLFVTPSRQFPTGAVLPXXXXXXXXXXXXXXXXXIVEDDYDSEFRWGGRPIEPLKALD 418 RL+++TPS Q+P GAV+ I+EDDYDSEFR G P+ ++ L Sbjct: 255 PRLIYITPSHQYPLGAVMSLERRLALLAQARAAGAWIIEDDYDSEFRHQGAPLSAVQGLT 314 Query: 419 HEERVIYIGSFSNSMFSGLRLGYAVLPPXXXXTRRQSA 456 + VIY+G+FS MF LRLG+ V+PP R++A Sbjct: 315 EDAPVIYLGTFSKVMFPALRLGFMVVPPALAPVLRRTA 352 >BH1940 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 400 Score = 137 bits (345), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 83/224 (37%), Positives = 116/224 (51%), Gaps = 5/224 (2%) Query: 227 ADGAFVSFRSRGMLMEHFPYAEWRSALKYAGGKSGGLLEGYCPPQGEEGLRRAIAAHLRV 286 ++ + + FRS ++ FP W + + Y PQG LR A++ +++ Sbjct: 102 SEPSIIQFRSGIPALDLFPRRIWGKLTQSICYEVEASAFNYDVPQGRPELREALSKYVKN 161 Query: 287 TRGIRAEAEHIVLFSGSMQGIVLLAQLLLEPGSPAVVEDPGFHGIRRAVEISGGELLLGR 346 RGI E IV+ +G+ Q L ++LL+ PG V+EDP I+ G +L+ Sbjct: 162 ARGIECHPEQIVITTGATQAFTLASKLLVSPGDELVIEDPITSDIQVIFTNHGAKLIPVP 221 Query: 347 VDESG----LVPQDWAARLLFVTPSRQFPTGAVLPXXXXXXXXXXXXXXXXXIVEDDYDS 402 VD+SG L+PQD +FVTPS QFP G VL IVEDDYDS Sbjct: 222 VDDSGIQTCLLPQDTKPAFVFVTPSHQFPLGGVLSIQRRVELIQYARKRNSYIVEDDYDS 281 Query: 403 EFRWGGRPIEPLKALDHEERVIYIGSFSNSMFSGLRLGYAVLPP 446 EFR+ G PI L+ L +RV+Y+GSFS + LRLGY +LPP Sbjct: 282 EFRYEGAPIPSLQGL-APDRVLYVGSFSKLLSPSLRLGYLILPP 324 >mlr6174 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 301 Score = 134 bits (338), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 0/243 (0%), Positives = 0/243 (0%), Gaps = 6/243 (2%) Query: 207 IPLSSWGNRLMHR-HVSIYEPADGAFVSFRSRGMLMEHFPYAEWRSALKYAGGKSGGLLE 265 L + S + + Sbjct: 100 RWTPDDEMVLNKLREGKAPVI-LAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAE- 157 Query: 266 GYCPPQGEEGLRRAIAAHLRVTRGIRAEAEHIVLFSGSMQGIVLLAQLLLEPGSPAVVED 325 + R + F S L + L +V + Sbjct: 158 TGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVE 217 Query: 326 PGFHGIRRAVEISGGELLLGRVDESGLVPQDW---AARLLFVTPSRQFPTGAVLPXXXXX 382 L+L + + + + + + P Sbjct: 218 IERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLEL 277 Query: 383 XXXXXXXXXXXXIVEDDYDSEFRWGGRPIEPLKALDHEERVIYIGSFSNSMFSGLRLGYA 442 Sbjct: 278 337 Query: 443 VLP 445 Sbjct: 338 340 >YPO2845 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 501 Score = 134 bits (337), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 73/207 (35%), Positives = 114/207 (55%), Gaps = 5/207 (2%) Query: 244 FPYAEWRSALKYAGGKSGGLLEGYCPPQGEEGLRRAIAAHLRVTRGIRAEAEHIVLFSGS 303 FP+ WR Y G L++A+A +LR+ R + + I++ +G+ Sbjct: 146 FPHEVWRKLQTRLSRHLNPENLTYSVHGGCPQLQQALADYLRIARSVSCTPDQILITAGT 205 Query: 304 MQGIVLLAQLLLEPGSPAVVEDPGFHGIRRAVEISGGELLLGRVDESGLVPQDW-----A 358 Q + LLA++L +PG A +E+P + GIR + I+G E++ VDE+G+ P D + Sbjct: 206 HQALDLLAKMLCDPGDHAWIEEPSYWGIRNVLTINGIEVIPVSVDENGMDPLDLPFESRS 265 Query: 359 ARLLFVTPSRQFPTGAVLPXXXXXXXXXXXXXXXXXIVEDDYDSEFRWGGRPIEPLKALD 418 RL+ VTPS Q+P G+V+ +VEDDYDSEFR+ G PI L+ L Sbjct: 266 PRLICVTPSHQYPLGSVMSLTRRQRILALAQQHNCWVVEDDYDSEFRFSGSPIPALQGLI 325 Query: 419 HEERVIYIGSFSNSMFSGLRLGYAVLP 445 + VIY+G+FS +++ G+R+ Y VLP Sbjct: 326 PDAPVIYLGTFSKTLYPGMRISYMVLP 352 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 32,255,666 Number of extensions: 1318757 Number of successful extensions: 7451 Number of sequences better than 1.0e-05: 83 Number of HSP's gapped: 7384 Number of HSP's successfully gapped: 84 Length of query: 457 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 347 Effective length of database: 25,691,691 Effective search space: 8915016777 Effective search space used: 8915016777 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 117 (49.7 bits)