BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0386.0035.p
         (219 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AGc3262 [Q] COG2761 Predicted dithiol-disulfide isomerase involv...   108   6e-24
BH1902 [Q] COG2761 Predicted dithiol-disulfide isomerase involve...    62   8e-10
BS_ywbO [Q] COG2761 Predicted dithiol-disulfide isomerase involv...    59   8e-09

>AGc3262 [Q] COG2761 Predicted dithiol-disulfide isomerase involved in
           polyketide biosynthesis
          Length = 452

 Score =  108 bits (270), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 11/195 (5%), Positives = 29/195 (14%), Gaps = 7/195 (3%)

Query: 2   IGKRKFENALGMFTMKDKVDVVYRSYQLDPNAENRTLSNEQLAQEKGMNVEQLKAKQAHV 61
                                ++            T  +                     
Sbjct: 39  ERAIDVLEKGMAIPRSVYALDIWGRDVHAAGLAEGTG-DPDGFCFPVPGTLSRV--TWLG 95

Query: 62  ANM-IKKEAGFDVSYDQVVI-ANTFDGHRLVHFADKAGKGAE--LTERLFRAYLSQRMNI 117
                   A  +                 L  +             E      +   ++ 
Sbjct: 96  RPTAQVLLAMKNADGTGFYGDPRHVLSQVLNAYKKAGLTPVVATELEFYLIDPVRSALDP 155

Query: 118 ADHNVLVALGSEAGLNEQYVAEMLKSDAYKDSVKADIAEARNLNISSLPTFVFNNKYVIS 177
                        G  +      L+         A    A+ +   +        +Y I+
Sbjct: 156 VRPPHSREGRWHTGQTQVLSISELQDFEDVFHDIATACRAQGVLADTTLRENGPGQYEIN 215

Query: 178 GAQSEEVFLNALNSI 192
                +    A  ++
Sbjct: 216 LNHVPDALQAADFAV 230


>BH1902 [Q] COG2761 Predicted dithiol-disulfide isomerase involved in
           polyketide biosynthesis
          Length = 95

 Score = 62.0 bits (149), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 36/93 (38%), Positives = 57/93 (61%), Gaps = 10/93 (10%)

Query: 131 GLNEQYVAEMLKSDAYKDSVKADIAEARNLNISSLPTFVFNNKYVISGAQSEEVFLNALN 190
           GL+      +LKS+A+ D V+++ A+A++L +  +P FV N+KY +SGAQ  +VF+ AL 
Sbjct: 2   GLDTSETHVVLKSEAFSDQVRSEEAKAQSLQVRGVPYFVINDKYALSGAQPTDVFVRALK 61

Query: 191 SIWEKEKVLQELEKTEQSSGEDG-------CEV 216
            + ++EK  QEL K   + GE G       CE+
Sbjct: 62  QVLDEEK--QEL-KPLANEGEQGAACSDGSCEI 91


>BS_ywbO [Q] COG2761 Predicted dithiol-disulfide isomerase involved in
           polyketide biosynthesis
          Length = 200

 Score = 58.5 bits (140), Expect = 8e-09,   Method: Compositional matrix adjust.
 Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)

Query: 91  HFADKAGKGAELTERLFRAYLSQRMNIADHNVLVALGSEAGLNEQYVAEMLKSDAYKDSV 150
           HFA +  KG E   R+F+A+  +  NI D ++L  L  E GL+       L++  Y+D  
Sbjct: 95  HFAKEYNKGHEYNTRVFQAFFQEDQNIGDIDILTKLAEEVGLDGASFKSALETRTYQDVQ 154

Query: 151 KADIAEA-RNLNISSLPTFVFNNKYVISGAQSEEVFLNALN 190
           +  +  A    +I+++PTF+  +  VI GA  ++VF  A++
Sbjct: 155 RQALKHAYEEADITAVPTFIIGDT-VIPGAAGKDVFEKAIS 194


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.313    0.129    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 14,988,664
Number of extensions: 549783
Number of successful extensions: 996
Number of sequences better than 1.0e-05: 3
Number of HSP's gapped: 997
Number of HSP's successfully gapped: 3
Length of query: 219
Length of database: 38,378,431
Length adjustment: 102
Effective length of query: 117
Effective length of database: 26,614,363
Effective search space: 3113880471
Effective search space used: 3113880471
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 114 (48.5 bits)