BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0386.0018.p (155 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1527 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 225 2e-59 SA1329 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 220 6e-58 BS_fur [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 214 4e-56 lin2070 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 203 7e-53 CAC1682 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 149 2e-36 >BH1527 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 150 Score = 225 bits (574), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 105/144 (72%), Positives = 128/144 (88%) Query: 1 MEARIDKIKQQLQSQGYKLTPQREATLRVLLENEEDHLSAEDVFMLVKEKAPEIGLATVY 60 ME R+D+IK+QL SQ YKLTPQREAT++VLLE+EEDHLSAEDV++LVKEKAPEIGLATVY Sbjct: 1 MEKRLDRIKKQLHSQSYKLTPQREATVKVLLEHEEDHLSAEDVYLLVKEKAPEIGLATVY 60 Query: 61 RTLELLSELHVVEKINFGDGVARYDLRTDTAKHHHHHLICVQCGTMDEIREDWLGPLEER 120 RTLELL+EL VV+KINFGDGV+RYDLR + A H HHHL+C++CG +DEI+ED LG +EE Sbjct: 61 RTLELLTELKVVDKINFGDGVSRYDLRQEGADHFHHHLVCIECGAVDEIQEDLLGDVEEI 120 Query: 121 LEKEFNFTVLDHRLDFHGICYRCK 144 +E E+NF + DHRL FHGIC+RC+ Sbjct: 121 VESEWNFKIKDHRLTFHGICHRCQ 144 >SA1329 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 149 Score = 220 bits (561), Expect = 6e-58, Method: Compositional matrix adjust. Identities = 102/147 (69%), Positives = 125/147 (85%) Query: 1 MEARIDKIKQQLQSQGYKLTPQREATLRVLLENEEDHLSAEDVFMLVKEKAPEIGLATVY 60 ME R++++KQQLQ YKLTPQREAT+RVL+ENE+DHLSAEDV++ VK+KAPEIGLATVY Sbjct: 1 MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVYLKVKDKAPEIGLATVY 60 Query: 61 RTLELLSELHVVEKINFGDGVARYDLRTDTAKHHHHHLICVQCGTMDEIREDWLGPLEER 120 RTLELL+EL VV+KINFGDGVAR+DLR + AKH HHHL+C++CG +DEI ED L +E R Sbjct: 61 RTLELLAELKVVDKINFGDGVARFDLRKEGAKHFHHHLVCMECGRVDEIDEDLLPEVENR 120 Query: 121 LEKEFNFTVLDHRLDFHGICYRCKDKN 147 +E EFNF +LDHRL FHG+C C+ K Sbjct: 121 VENEFNFKILDHRLTFHGVCETCQAKG 147 >BS_fur [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 149 Score = 214 bits (545), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 102/146 (69%), Positives = 123/146 (84%) Query: 1 MEARIDKIKQQLQSQGYKLTPQREATLRVLLENEEDHLSAEDVFMLVKEKAPEIGLATVY 60 ME RID+IK+QL S YKLTPQREAT+RVLLENEEDHLSAEDV++LVKEK+PEIGLATVY Sbjct: 1 MENRIDRIKKQLHSSSYKLTPQREATVRVLLENEEDHLSAEDVYLLVKEKSPEIGLATVY 60 Query: 61 RTLELLSELHVVEKINFGDGVARYDLRTDTAKHHHHHLICVQCGTMDEIREDWLGPLEER 120 RTLELL+EL VV+KINFGDGV+RYDLR + A H HHHL+C++ G +DEI D L +EE Sbjct: 61 RTLELLTELKVVDKINFGDGVSRYDLRKEGAAHFHHHLVCMEFGAVDEIEGDLLEDVEEI 120 Query: 121 LEKEFNFTVLDHRLDFHGICYRCKDK 146 +E+++ F + DHRL FHGIC+RC K Sbjct: 121 IERDWKFKIKDHRLTFHGICHRCNGK 146 >lin2070 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 152 Score = 203 bits (517), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 96/152 (63%), Positives = 124/152 (81%) Query: 1 MEARIDKIKQQLQSQGYKLTPQREATLRVLLENEEDHLSAEDVFMLVKEKAPEIGLATVY 60 ME RI +IK QL YKLTPQREAT+RVLLENE+DHLSAE+VF+ VK+ AP+ GLATVY Sbjct: 1 MEGRIGRIKAQLHDASYKLTPQREATVRVLLENEKDHLSAEEVFLRVKDIAPDTGLATVY 60 Query: 61 RTLELLSELHVVEKINFGDGVARYDLRTDTAKHHHHHLICVQCGTMDEIREDWLGPLEER 120 RTLELL+EL VV+KINFGDGV+RYDLR + AKH HHHL+C++CG+++EI+ED L +E+ Sbjct: 61 RTLELLTELRVVDKINFGDGVSRYDLRQEGAKHFHHHLVCLECGSVEEIQEDLLEDVEKI 120 Query: 121 LEKEFNFTVLDHRLDFHGICYRCKDKNNTDSN 152 +E ++NF V DHRL F GIC C+ K+ +++ Sbjct: 121 VESKWNFLVKDHRLTFQGICADCRQKSKKNNS 152 >CAC1682 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 151 Score = 149 bits (376), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 67/142 (47%), Positives = 102/142 (71%) Query: 5 IDKIKQQLQSQGYKLTPQREATLRVLLENEEDHLSAEDVFMLVKEKAPEIGLATVYRTLE 64 I+K+K L+ +GYKLTPQR A L ++++NE HL+ E+++ LVK + PEIGLATVYRT++ Sbjct: 9 IEKLKNNLKDKGYKLTPQRRAVLDIIIDNEGQHLTVEELYDLVKLECPEIGLATVYRTVQ 68 Query: 65 LLSELHVVEKINFGDGVARYDLRTDTAKHHHHHLICVQCGTMDEIREDWLGPLEERLEKE 124 LL EL V+ K++ DG++RY+L + H HHHLIC CG + E++ D L LE+ +E + Sbjct: 69 LLDELGVISKLDLNDGLSRYELVHENEPHQHHHLICTACGKVTEVQGDLLDELEDCIENK 128 Query: 125 FNFTVLDHRLDFHGICYRCKDK 146 ++F + +H + F+GIC C+ K Sbjct: 129 YHFLIKNHSVKFYGICSECRKK 150 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 11,667,801 Number of extensions: 454105 Number of successful extensions: 2514 Number of sequences better than 1.0e-05: 387 Number of HSP's gapped: 2136 Number of HSP's successfully gapped: 387 Length of query: 155 Length of database: 38,378,431 Length adjustment: 97 Effective length of query: 58 Effective length of database: 27,191,033 Effective search space: 1577079914 Effective search space used: 1577079914 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 111 (47.4 bits)