BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0386.0014.p (201 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2079 [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 189 3e-48 BH1524 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 176 3e-44 BS_yqkG [LR] COG0494 NTP pyrophosphohydrolases including oxidati... 174 1e-43 SA1330 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 150 1e-36 SP0989 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ... 143 2e-34 >lin2079 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 189 bits (479), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 13/175 (7%), Positives = 39/175 (22%), Gaps = 3/175 (1%) Query: 22 ALDEETLSTKPIFVGKIISLQVDTVKLPDGNTATREVVKHPGAVAVLALN-QGKMLVVEQ 80 + + + + ++ + K +++ G A + Sbjct: 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAARE 62 Query: 81 YRQPMHRTEVEIPAGKLDPGEDPLAAAGRELQEETGFHSGELKLLKSFYTSPGFADEIIH 140 ++ + +T A L +E L E+ Sbjct: 63 MKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTE 122 Query: 141 LYVTDNAQPGD--MALDEDEFLEVSELTLEEAYQYIADGRIADAKTMMAVYAWHL 193 + D+ ++ + ++ + A RI + Sbjct: 123 GLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKA 177 >BH1524 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 176 bits (445), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 12/178 (6%), Positives = 30/178 (16%), Gaps = 1/178 (0%) Query: 20 NPALDEETLSTKPIFVGKIISLQVDTVKLPDGNTATREVVKHPGAVAVLALNQ-GKMLVV 78 ++ +++ N + +A Sbjct: 2 RLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAR 61 Query: 79 EQYRQPMHRTEVEIPAGKLDPGEDPLAAAGRELQEETGFHSGELKLLKSFYTSPGFADEI 138 E + + G + L + + L + Sbjct: 62 EMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELT 121 Query: 139 IHLYVTDNAQPGDMALDEDEFLEVSELTLEEAYQYIADGRIADAKTMMAVYAWHLFTL 196 L D + + + + A I + A A Sbjct: 122 EGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACN 179 >BS_yqkG [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 174 bits (440), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 13/175 (7%), Positives = 38/175 (21%), Gaps = 3/175 (1%) Query: 22 ALDEETLSTKPIFVGKIISLQVDTVKLPDGNTATREVVKHPGAVAVLAL-NQGKMLVVEQ 80 + + + + ++ + K +++ G A + Sbjct: 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAARE 62 Query: 81 YRQPMHRTEVEIPAGKLDPGEDPLAAAGRELQEETGFHSGELKLLKSFYTSPGFADEIIH 140 ++ + +T A L +E L E+ Sbjct: 63 MKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTE 122 Query: 141 LYVTD--NAQPGDMALDEDEFLEVSELTLEEAYQYIADGRIADAKTMMAVYAWHL 193 + D ++ + ++ + A RI + Sbjct: 123 GLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKA 177 >SA1330 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 150 bits (379), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 10/167 (5%), Positives = 29/167 (17%), Gaps = 1/167 (0%) Query: 23 LDEETLSTKPIFVGKIISLQVDTVKLPDGNTATREVVKHPGAVAVLALNQGK-MLVVEQY 81 L+ G + L T + + + Sbjct: 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAARE 62 Query: 82 RQPMHRTEVEIPAGKLDPGEDPLAAAGRELQEETGFHSGELKLLKSFYTSPGFADEIIHL 141 + + + ++ E + T + + Sbjct: 63 MKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTE 122 Query: 142 YVTDNAQPGDMALDEDEFLEVSELTLEEAYQYIADGRIADAKTMMAV 188 + ++ + L ++L A G Sbjct: 123 GLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYG 169 >SP0989 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes Length = 673 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 13/181 (7%), Positives = 30/181 (16%), Gaps = 15/181 (8%) Query: 23 LDEETLSTKPIFVGKIISLQVDTVKLPDGN-TATREVVKHPGAVAVLAL-NQGKMLVVEQ 80 L+ G + L +++ G A + Sbjct: 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAARE 62 Query: 81 YRQPMHRTEVEIPAGKLDPGED--PLAAAGRELQEETGFHSGELKLLKSFYTSPGFADEI 138 ++ + +T A L + G L + Sbjct: 63 MKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGM-KANFSLFDDTDQLALLKELT 121 Query: 139 IHLYV------TDNAQPGDMALDEDEFLEVSELTLEEAYQYIADGRIADAKTMMAVYAWH 192 L + + + D A + + Sbjct: 122 EGLIEDDKVLLQQLISTIS----NWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKA 177 Query: 193 L 193 Sbjct: 178 C 178 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.315 0.133 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,297,481 Number of extensions: 645036 Number of successful extensions: 1132 Number of sequences better than 1.0e-05: 42 Number of HSP's gapped: 1091 Number of HSP's successfully gapped: 42 Length of query: 201 Length of database: 38,378,431 Length adjustment: 101 Effective length of query: 100 Effective length of database: 26,729,697 Effective search space: 2672969700 Effective search space used: 2672969700 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 113 (48.1 bits)